Endothelial Src kinase regulates membrane recycling from the lateral border recycling compartment duringleukocyte transendothelial migration

European Journal of Immunology

Volumn 38, Issue 12, 2008, Pages 3499-3507

  Dasgupta, Bidisha ^a   Muller, William A ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Lateral border recycling compartment; Leukocyte transendothelial migration; PECAM

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CD31 ANTIGEN; PROTEIN TYROSINE KINASE; CELL ADHESION MOLECULE; PHOSPHOTYROSINE; PROTEIN KINASE INHIBITOR;

ARTICLE; CELL COMPARTMENTALIZATION; CELL INTERACTION; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEUKOCYTE MIGRATION; PRIORITY JOURNAL; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; CELL CULTURE; CELL MOTION; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; IMMUNOLOGY; LEUKOCYTE; METABOLISM; UMBILICAL CORD;

CELL ADHESION MOLECULES; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL CELLS; HUMANS; LEUKOCYTES; PHOSPHOTYROSINE; PROTEIN KINASE INHIBITORS; SRC-FAMILY KINASES; UMBILICAL CORD;

EID: 59749100770     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838605     Document Type: Article

References (31)

1. Muller, W. A., Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol. 2003. 24: 326-333.
2. Muller, W. A., Weigl, S. A., Deng, X. and Phillips, D. M., PECAM-1 is required for transendothelial migration of leukocytes. J. Exp. Med. 1993. 178: 449-460.
3. Liao, F., Huynh, H. K., Eiroa, A., Greene, T., Polizzi, E. and Muller, W. A., Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1. J. Exp. Med. 1995. 182: 1337-1343.
4. Liao, F., Ali, J., Greene, T. and Muller, W. A., Soluble domain 1 of platelet-endothelial cell adhesion molecule (PECAM) is sufficient to block transendothelial migration in vitro and in vivo. J. Exp. Med. 1997. 185: 1349-1357.
5. Liao, F., Schenkel, A. R. and Muller, W. A., Transgenic mice expressing different levels of soluble platelet/endothelial cell adhesion molecule-IgG display distinct inflammatory phenotypes. J. Immunol. 1999. 163: 5640-5648.
6. Schenkel, A. R., Mamdouh, Z., Chen, X., Liebman, R. M. and Muller, W. A., CD99 plays a major role in the migration of monocytes through endothelial junctions. Nat. Immunol. 2002. 3: 143-150.
7. Huang, M. T., Larbi, K. Y., Scheiermann, C., Woodfin, A., Gerwin, N., Haskard, D. O. and Nourshargh, S., ICAM-2 mediates neutrophil transmigration in vivo: Evidence for stimulus specificity and a role in PECAM-1-independent transmigration. Blood 2006. 107: 4721-4727.
8. 2 integrin LFA-1 involved in transendothelial migration of leukocytes. Nat. Immunol. 2002. 3: 151-158.
9. Weber, C., Fraemohs, L. and Dejana, E., The role of junctional adhesion molecules in vascular inflammation. Nat. Rev. Immunol. 2007. 7: 467-477.
10. Reymond, N., Imbert, A. M., Devilard, E., Fabre, S., Chabannon, C., Xerri, L., Farnarier, C. et al., DNAM-1 and PVR regulate monocyte migration through endothelial junctions. J. Exp. Med. 2004. 199: 1331-1341.
11. Mamdouh, Z., Chen, X., Pierini, L. M., Maxfield, F. R. and Muller, W. A., Targeted recycling of PECAM from endothelial cell surface-connected compartments during diapedesis. Nature 2003. 421: 748-753.
12. Mamdouh, Z., Kreitzer, G. E. and Muller, W. A., Leukocyte transmigration requires kinesin-mediated microtubule-dependent membrane trafficking from the lateral border recycling compartment. J. Exp. Med. 2008. 205: 951-966.
13. Yang, L, Kowalski J. R., Zhan, X., Thomas, S. M. and Luscinskas, F. W., Endothelial cell cortactin phosphorylation by Src contributes to polymorphonuclear leukocyte transmigration in vitro. Circ. Res. 2006. 98: 394-402.
14. Muller, W. A., PECAM-1: An adhesion molecule at the junctions of endothelial cells, in: Van Furth, R, Cohn, Z. A. and Gordon, S. (Eds.), Proceedings of the Fifth Leiden Meeting on Mononuclear Phagocytes, Blackwell, London 1992, pp. 138-148.
15. Schenkel, A. R., Mamdouh, Z. and Muller, W. A., Locomotion of monocytes on endothelium is a critical step during extravasation. Nat. Immunol. 2004. 5: 393-400.
16. Bird, I., Taylor, V., Newton, J., Spragg, J., Simmons, D., Salmon, M. and Buckley, C., Homophilic PECAM-1(CD31) interactions prevent endothelial cell apoptosis but do not support cell spreading or migration. J. Cell Sci. 1999. 112: 1989-1997.
17. Lu, T. T., Yan, L. G. and Madri, J. A., Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule Proc. Natl. Acad. Sci. USA 1996. 93: 11808-11813.
18. Kogata, N., Masuda, M., Kamioka, Y., Yamagishi, A., Endo, A., Okada, M. and Mochizuki, N., Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells. Mol. Biol. Cell 2003. 14: 3553-3564.
19. Giorgetti-Peraldi, S., Murdaca, J., Mas, J. C. and Van Obberghen, E., The adapter protein, Grb10, is a positive regulator of vascular endothelial growth factor signaling. Oncogene 2001. 20: 3959-3968.
20. Weber, C., Negrescu, E., Erl, W., Pietsch, A., Frankenberger, M., Ziegler-Heitbrock, H. W., Siess, W. and Weber, P. C., Inhibitors of protein tyrosine kinase suppress TNF-stimulated induction of endothelial cell adhesion molecules. J. Immunol. 1995. 155: 445-451.
21. Cicmil, M., Thomas, J. M., Sage, T., Barry, F. A., Leduc, M., Bon, C. and Gibbins, J. M., Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. J. Biol. Chem. 2000. 275: 27339-27347.
22. Kalra, V. K., Shen, Y., Sultana, C. and Rattan, V., Hypoxia induces PECAM-1 phosphorylation and transendothelial migration of monocytes. Am. J. Physiol. 1996. 271: H2025-H2034.
23. Rattan, V., Shen, Y., Sultana, C., Kumar, D. and Kalra, V. K., Glucose-induced transmigration of monocytes is linked to phosphorylation of PECAM-1 in cultured endothelial cells. Am. J. Physiol. 1996. 271: E711-E717.
24. van Buul, J. D., Allingham, M. J., Samson, T., Meller, J., Boulter, E., Garcia-Mata, R. and Burridge, K., RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration. J. Cell Biol. 2007. 178: 1279-1293.
25. Ilan, N. and Madri, J. A., PECAM-1: Old friend, new partners. Curr. Opin. Cell Biol. 2003. 15: 515-524.
26. Gratzinger, D., Barreuther, M. and Madri, J. A., Platelet-endothelial cell adhesion molecule-1 modulates endothelial migration through its immunoreceptor tyrosine-based inhibitory motif. Biochem. Biophys. Res. Commun. 2003. 301: 243-249.
27. Masuda, M., Osawa, M., Shigematsu, H., Harada, N. and Fujiwara, K., Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells. FEBS Lett. 1997. 408: 331-336.
28. Sagawa, K., Kimura, T., Swieter, M. and Siraganian, R. P., The protein-tyrosine phosphatase SHP-2 associates with tyrosine-phosphorylated adhesion molecule PECAM-1 (CD31). J. Biol. Chem. 1997. 272: 31086-31091.
29. Newton-Nash, D. K. and Newman, P. J., A new role for platelet-endothelial cell adhesion molecule-1 (CD31): Inhibition of TCR-mediated signal transduction. J. Immunol. 1999. 163: 682-688.
30. Muller, W. A., Ratti, C. M., McDonnell, S. L. and Cohn, Z. A., A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J. Exp. Med. 1989. 170: 399-414.
31. Muller, W. A. and Weigl, S., Monocyte-selective transendothelial migration: Dissection of the binding and transmigration phases by an in vitro assay. J. Exp. Med. 1992. 176: 819-828.