Omega-3 fatty acids exacerbate DSS-induced colitis through decreased adiponectin in colonic subepithelial myofibroblasts

Inflammatory Bowel Diseases

Volumn 14, Issue 10, 2008, Pages 1348-1357

  Matsunaga, Hisayuki ^a   Hokari, Ryota ^a   Kurihara, Chie ^a   Okada, Yoshikiyo ^a   Takebayashi, Koichi ^a   Okudaira, Keisuke ^a   Watanabe, Chikako ^a   Komoto, Syunsuke ^a   Nakamura, Mitsuyasu ^a   Tsuzuki, Yoshikazu ^a   Kawaguchi, Atushi ^a   Nagao, Shigeaki ^a   Itoh, Kazuro ^a   Miura, Soichiro ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Adiponectin; Colon; Inflammation; Mice; Myofibroblast; Omega 3 fatty acids

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR; DEXTRAN SULFATE; MESSENGER RNA; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; SATURATED FATTY ACID; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIINFLAMMATORY AGENT; EDIBLE OIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; COLON MUCOSA; CONTROLLED STUDY; DIETARY INTAKE; EPITHELIUM CELL; FAT INTAKE; LYMPHOCYTE; MALE; MONONUCLEAR CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; UBIQUITINATION; ULCERATIVE COLITIS; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED DISORDER; COLITIS; DISEASE MODEL; GENE EXPRESSION; GENETICS; HUMAN; INTESTINE MUCOSA; METABOLISM; MYOBLAST; PATHOLOGY; RANDOMIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADIPONECTIN; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; COLITIS; DEXTRAN SULFATE; DIETARY FATS; DIETARY FATS, UNSATURATED; DISEASE MODELS, ANIMAL; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; GENE EXPRESSION; HUMANS; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED C57BL; MYOBLASTS; RANDOM ALLOCATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THIAZOLIDINEDIONES;

EID: 59749091374     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.20491     Document Type: Article

References (39)

1. Shoda R, Matsueda K, Yamato S, et al. Epidemiologic analysis of Crohn disease in Japan: increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan. Am J Clin Nutr. 1996;63:741-745.
2. Lorenz-Meyer H, Bauer P, Nicolay C, et al. Omega-3 fatty acids and low carbohydrate diet for maintenance of remission in Crohn's disease. A randomized controlled multicenter trial. Study Group Members (German Crohn's Disease Study Group). Scand J Gastroenterol. 1996;31:778-785.
3. MacLean CH, Mojica WA, Newberry SJ, et al. Systematic review of the effects of n-3 fatty acids in inflammatory bowel disease. Am J Clin Nutr. 2005;82:611-619.
4. Bamba T, Shimoyama T, Sasaki M, et al. Dietary fat attenuates the benefits of an elemental diet in active Crohn's disease: a randomized, controlled trial. Eur J Gastroenterol Hepatol. 2003;15:151-157.
5. Miura S, Tsuzuki Y, Hokari R, et al. Modulation of intestinal immune system by dietary fat intake: relevance to Crohn's disease. J Gastroenterol Hepatol. 1998;13:1183-1190.
6. French MA, Parrott AM, Kielo ES, et al. Polyunsaturated fat in the diet may improve intestinal function in patients with Crohn's disease. Biochim Biophys Acta. 1997;1360:262-270.
7. Alzoghaibi MA, Walsh SW, Willey A, et al. Linoleic acid induces interleukin-8 production by Crohn's human intestinal smooth muscle cells via arachidonic acid metabolites. Am J Physiol Gastrointest Liver Physiol. 2004;286:G528-537.
8. James MJ, Gibson RA, Cleland LG. Dietary polyunsaturated fatty acids and inflammatory mediator production. Am J Clin Nutr. 2000;71:343S-348S.
9. Hara Y, Miura S, Komoto S, et al. Exposure to fatty acids modulates interferon production by intraepithelial lymphocytes. Immunol Lett. 2003;86:139-148.
10. Yoshida H, Miura S, Kishikawa H, et al. Fatty acids enhance GRO/CINC-1 and interleukin-6 production in rat intestinal epithelial cells. J Nutr. 2001;131:2943-2950.
11. Tsuzuki Y, Miura S, Kurose I, et al. Enhanced lymphocyte interaction in postcapillary venules of Peyer's patches during fat absorption in rats. Gastroenterology. 1997;112:813-825.
12. Reif S, Klein I, Lubin F, et al. Pre-illness dietary factors in inflammatory bowel disease. Gut. 1997;40:754-760.
13. Shoda R, Matsueda K, Yamato S, et al. Therapeutic efficacy of N-3 polyunsaturated fatty acid in experimental Crohn's disease. J Gastroenterol. 1995;30(suppl 8):98-101.
14. Whiting CV, Bland PW, Tarlton JF. Dietary n-3 polyunsaturated fatty acids reduce disease and colonic proinflammatory cytokines in a mouse model of colitis. Inflamm Bowel Dis. 2005;11:340-349.
15. Camuesco D, Galvez J, Nieto A, et al. Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n-3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis. J Nutr. 2005;135:687- 694.
16. Sanderson P, MacPherson GG, Jenkins CH, et al. Dietary fish oil diminishes the antigen presentation activity of rat dendritic cells. J Leukoc Biol. 1997;62:771-777.
17. Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors. Endocr Rev. 2005;26:439-451.
18. Xu A, Wang Y, Keshaw H, et al. The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest. 2003;112:91-100.
19. Kaser S, Moschen A, Cayon A, et al. Adiponectin and its receptors in non-alcoholic steatohepatitis. Gut. 2005;54:117-121.
20. Masaki T, Chiba S, Tatsukawa H, et al. Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice. Hepatology. 2004;40:177-184.
21. Nishihara T, Matsuda M, Araki H, et al. Effect of adiponectin on murine colitis induced by dextran sulfate sodium. Gastroenterology. 2006;131: 853-861.
22. Fayad R, Pini M, Sennello JA, et al. Adiponectin deficiency protects mice from chemically induced colonic inflammation. Gastroenterology. 2007;132:601- 614.
23. Yamamoto K, Kiyohara T, Murayama Y, et al. Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. Gut. 2005;54:789-796.
24. Ogunwobi OO, Beales IL. Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regul Pept. 2006;134:105-113.
25. Hokari R, Kato S, Matsuzaki K, et al. Reduced sensitivity of inducible nitric oxide synthase-deficient mice to chronic colitis. Free Radic Biol Med. 2001;31:153-163.
26. Umezawa M, Tatematsu K, Korenaga T, et al. Dietary fat modulation of apoA-II metabolism and prevention of senile amyloidosis in the senescence-accelerated mouse. J Lipid Res. 2003;44:762-769.
27. Maeda N, Takahashi M, Funahashi T, et al. PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes. 2001;50:2094-2099.
28. Kanatani Y, Usui I, Ishizuka K, et al. Effects of pioglitazone on suppressor of cytokine signaling 3 expression: potential mechanisms for its effects on insulin sensitivity and adiponectin expression. Diabetes. 2007; 56:795-803.
29. Jaimes MC, Feng N, Greenberg HB. Characterization of homologous and heterologous rotavirus-specific T-cell responses in infant and adult mice. J Virol. 2005;79:4568-4579.
30. Mahida YR, Beltinger J, Makh S, et al. Adult human colonic subepithelial myofibroblasts express extracellular matrix proteins and cyclooxygenase-1 and -2. Am J Physiol. 1997;273:G1341-1348.
31. Belluzzi A, Brignola C, Campieri M, et al. Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. N Engl J Med. 1996;334:1557-1560.
32. Lorente-Cebrian S, Perez-Matute P, Martinez JA, et al. Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes. J Physiol Biochem. 2006;62:61-69.
33. Ehling A, Schaffler A, Herfarth H, et al. The potential of adiponectin in driving arthritis. J Immunol. 2006;176:4468-4478.
34. Tang CH, Chiu YC, Tan TW, et al. Adiponectin enhances IL-6 production in human synovial fibroblast via an AdipoR1 receptor, MAPK, p38, and NF-kappa B pathway. J Immunol. 2007;179:5483-5492.
35. Barnea M, Shamay A, Stark AH, et al. A high-fat diet has a tissue-specific effect on adiponectin and related enzyme expression. Obesity (Silver Spring). 2006;14:2145-2153.
36. Ouchi N, Kihara S, Arita Y, et al. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation. 2000;102:1296-1301.
37. Kapadia R, Yi JH, Vemuganti R. Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists. Front Biosci. 2008; 13:1813-1826.
38. Takaki K, Mitsuyama K, Tsuruta O, et al. Attenuation of experimental colonic injury by thiazolidinedione agents. Inflamm Res. 2006;55:10-15.
39. Schaefer KL, Denevich S, Ma C, et al. Intestinal antiinflammatory effects of thiazolidenedione peroxisome proliferator-activated receptorgamma ligands on T helper type 1 chemokine regulation include nontranscriptional control mechanisms. Inflamm Bowel Dis. 2005;11:244-252.