메뉴 건너뛰기




Volumn 69, Issue 1, 2009, Pages 21-30

Development of newer calcium channel antagonists: Therapeutic potential of efonidipine in preventing electrical remodelling during atrial fibrillation

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; BEPRIDIL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL T TYPE; DILTIAZEM; EFONIDIPINE; ENALAPRIL; MIBEFRADIL; NIFEDIPINE; VERAPAMIL;

EID: 59749083760     PISSN: 00126667     EISSN: 00126667     Source Type: Journal    
DOI: 10.2165/00003495-200969010-00002     Document Type: Review
Times cited : (14)

References (73)
  • 1
    • 0024460849 scopus 로고
    • Calcium channel blockers in acute myocardial infarction and unstable angina: An overview
    • Nov 11;
    • Held PH, Yusuf S, Furberg CD. Calcium channel blockers in acute myocardial infarction and unstable angina: an overview. BMJ 1989 Nov 11; 299 (6709): 1187-92
    • (1989) BMJ , vol.299 , Issue.6709 , pp. 1187-1192
    • Held, P.H.1    Yusuf, S.2    Furberg, C.D.3
  • 2
    • 17744405878 scopus 로고    scopus 로고
    • Short-acting nifedipine and diltiazem do not reduce the incidence of cardiac events in patients with healed myocardial infarction
    • May 20;
    • Ishikawa K, Nakai S, Takenaka T, et al. Short-acting nifedipine and diltiazem do not reduce the incidence of cardiac events in patients with healed myocardial infarction. Circulation 1997 May 20; 95 (10): 2368-73
    • (1997) Circulation , vol.95 , Issue.10 , pp. 2368-2373
    • Ishikawa, K.1    Nakai, S.2    Takenaka, T.3
  • 3
    • 0030807893 scopus 로고    scopus 로고
    • Effect of calcium antagonists on plasma norepinephrine levels, heart rate, and blood pressure
    • Dec 1;
    • Grossman E, Messerli FH. Effect of calcium antagonists on plasma norepinephrine levels, heart rate, and blood pressure. Am J Cardiol 1997 Dec 1; 80 (11): 1453-8
    • (1997) Am J Cardiol , vol.80 , Issue.11 , pp. 1453-1458
    • Grossman, E.1    Messerli, F.H.2
  • 4
    • 0343487983 scopus 로고    scopus 로고
    • Randomized doubleblind comparison of placebo and active treatment for older patients with isolated systolic hypertension
    • Sep 13;
    • Staessen JA, Fagard R, Thijs L, et al. Randomized doubleblind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 1997 Sep 13; 350 (9080): 757-64
    • (1997) Lancet , vol.350 , Issue.9080 , pp. 757-764
    • Staessen, J.A.1    Fagard, R.2    Thijs, L.3
  • 5
    • 4544304433 scopus 로고    scopus 로고
    • Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): Randomised controlled trial
    • Sep 4;
    • Poole-Wilson PA, Lubsen J, Kirwan BA, et al. Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial. Lancet 2004 Sep 4; 364 (9437): 849-57
    • (2004) Lancet , vol.364 , Issue.9437 , pp. 849-857
    • Poole-Wilson, P.A.1    Lubsen, J.2    Kirwan, B.A.3
  • 6
    • 24644443331 scopus 로고    scopus 로고
    • Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): A multicentre randomised controlled trial
    • Sep 10-16;
    • Dahlof B, Sever PS, Poulter NR, et al. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet 2005 Sep 10-16; 366 (9489): 895-906
    • (2005) Lancet , vol.366 , Issue.9489 , pp. 895-906
    • Dahlof, B.1    Sever, P.S.2    Poulter, N.R.3
  • 7
    • 7744231805 scopus 로고    scopus 로고
    • Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure. The CAMELOT study: A randomized controlled trial
    • Nov 10;
    • Nissen SE, Tuzcu EM, Libby P, et al. Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure. The CAMELOT study: a randomized controlled trial. JAMA 2004 Nov 10; 292 (18): 2217-25
    • (2004) JAMA , vol.292 , Issue.18 , pp. 2217-2225
    • Nissen, S.E.1    Tuzcu, E.M.2    Libby, P.3
  • 8
    • 0037207469 scopus 로고    scopus 로고
    • Molecular physiology of low-voltage-activated t-type calcium channels
    • Jan;
    • Perez-Reyes E. Molecular physiology of low-voltage-activated t-type calcium channels. Physiol Rev 2003 Jan; 83 (1): 117-61
    • (2003) Physiol Rev , vol.83 , Issue.1 , pp. 117-161
    • Perez-Reyes, E.1
  • 9
    • 29844438166 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVII: Nomenclature and structure-function relationships of voltage-gated sodium channels
    • Dec;
    • Catterall WA, Goldin AL, Waxman SG. International Union of Pharmacology. XLVII: nomenclature and structure-function relationships of voltage-gated sodium channels. Pharmacol Rev 2005 Dec; 57 (4): 397-409
    • (2005) Pharmacol Rev , vol.57 , Issue.4 , pp. 397-409
    • Catterall, W.A.1    Goldin, A.L.2    Waxman, S.G.3
  • 10
    • 0023874003 scopus 로고
    • 2+ channels in evoked release of norepinephrine from sympathetic neurons
    • Jan 1;
    • 2+ channels in evoked release of norepinephrine from sympathetic neurons. Science 1988 Jan 1; 239 (4835): 57-61
    • (1988) Science , vol.239 , Issue.4835 , pp. 57-61
    • Hirning, L.D.1    Fox, A.P.2    McCleskey, E.W.3
  • 12
    • 0026721456 scopus 로고
    • Antihypertensive mechanism of amlodipine in essential hypertension: Role of pressor reactivity to norepinephrine and angiotensin II
    • Jul;
    • Donati L, Buhler FR, Beretta-Piccoli C, et al. Antihypertensive mechanism of amlodipine in essential hypertension: role of pressor reactivity to norepinephrine and angiotensin II. Clin Pharmacol Ther 1992 Jul; 52 (1): 50-9
    • (1992) Clin Pharmacol Ther , vol.52 , Issue.1 , pp. 50-59
    • Donati, L.1    Buhler, F.R.2    Beretta-Piccoli, C.3
  • 13
    • 0030054726 scopus 로고    scopus 로고
    • Comparison of the effects of amlodipine and diltiazem on 24-hour blood pressure, plasma catecholamines, and left ventricular mass
    • Jul 15;
    • Leenen FH, Fourney A. Comparison of the effects of amlodipine and diltiazem on 24-hour blood pressure, plasma catecholamines, and left ventricular mass. Am J Cardiol 1996 Jul 15; 78 (2): 203-7
    • (1996) Am J Cardiol , vol.78 , Issue.2 , pp. 203-207
    • Leenen, F.H.1    Fourney, A.2
  • 15
    • 7944225393 scopus 로고    scopus 로고
    • 2+ channel blocker cilnidipine assessed in the chronic atrioventricular conduction block dogs
    • Oct;
    • 2+ channel blocker cilnidipine assessed in the chronic atrioventricular conduction block dogs. J Pharmacol Sci 2004 Oct; 96 (2): 219-23
    • (2004) J Pharmacol Sci , vol.96 , Issue.2 , pp. 219-223
    • Takahara, A.1    Sugiyama, A.2    Satoh, Y.3
  • 16
    • 0023874297 scopus 로고
    • Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells
    • Hagiwara N, Irisawa H, Kameyama M. Contribution of two types of calcium currents to the pacemaker potentials of rabbit sino-atrial node cells. J Physiol 1988; 395: 233-53
    • (1988) J Physiol , vol.395 , pp. 233-253
    • Hagiwara, N.1    Irisawa, H.2    Kameyama, M.3
  • 17
    • 0141653536 scopus 로고    scopus 로고
    • 2+ release contributes to automaticity in cat atrial pacemaker cells
    • Apr 15;
    • 2+ release contributes to automaticity in cat atrial pacemaker cells. J Physiol 2000 Apr 15; 524 (Pt 2): 415-22
    • (2000) J Physiol , vol.524 , Issue.PART 2 , pp. 415-422
    • Hüser, J.1    Blatter, L.A.2    Lipsius, S.L.3
  • 18
    • 28044464474 scopus 로고    scopus 로고
    • 2+ channels in cardiac pacemaking
    • Nov;
    • 2+ channels in cardiac pacemaking. J Pharmacol Sci 2005 Nov; 99 (3): 197-204
    • (2005) J Pharmacol Sci , vol.99 , Issue.3 , pp. 197-204
    • Ono, K.1    Iijima, T.2
  • 19
    • 33745403607 scopus 로고    scopus 로고
    • Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/alpha1G T-type calcium channels
    • Jun 9;
    • Mangoni ME, Traboulsie A, Leoni AL, et al. Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/alpha1G T-type calcium channels. Circ Res 2006 Jun 9; 98 (11): 1422-30
    • (2006) Circ Res , vol.98 , Issue.11 , pp. 1422-1430
    • Mangoni, M.E.1    Traboulsie, A.2    Leoni, A.L.3
  • 21
    • 0034879821 scopus 로고    scopus 로고
    • 2+) channels
    • Jul 19;
    • 2+) channels. Neuron 2001 Jul 19; 31 (1): 35-45
    • (2001) Neuron , vol.31 , Issue.1 , pp. 35-45
    • Kim, D.1    Song, I.2    Keum, S.3
  • 22
    • 0141642208 scopus 로고    scopus 로고
    • 2+ channels
    • Oct 3;
    • 2+ channels. Science 2003 Oct 3; 302 (5642): 117-9
    • (2003) Science , vol.302 , Issue.5642 , pp. 117-119
    • Kim, D.1    Park, D.2    Choi, S.3
  • 23
    • 18744383129 scopus 로고    scopus 로고
    • Functional characterization and neuronal modeling of the effects of childhood absence epilepsy variants of CACNA1H, a T-type calcium channel
    • May 11;
    • Vitko I, Chen Y, Arias JM, et al. Functional characterization and neuronal modeling of the effects of childhood absence epilepsy variants of CACNA1H, a T-type calcium channel. J Neurosci 2005 May 11; 25 (19): 4844-55
    • (2005) J Neurosci , vol.25 , Issue.19 , pp. 4844-4855
    • Vitko, I.1    Chen, Y.2    Arias, J.M.3
  • 24
    • 0034700973 scopus 로고    scopus 로고
    • Effect of mibefradil, a T-type calcium channel blocker, on morbidity and mortality in moderate to severe congestive heart failure: The MACH-1 study. Mortality Assessment in Congestive Heart Failure Trial
    • Feb 22;
    • Levine TB, Bernink PJ, Caspi A, et al. Effect of mibefradil, a T-type calcium channel blocker, on morbidity and mortality in moderate to severe congestive heart failure: the MACH-1 study. Mortality Assessment in Congestive Heart Failure Trial. Circulation 2000 Feb 22; 101 (7): 758-64
    • (2000) Circulation , vol.101 , Issue.7 , pp. 758-764
    • Levine, T.B.1    Bernink, P.J.2    Caspi, A.3
  • 25
    • 0035740714 scopus 로고    scopus 로고
    • Torsades de pointes caused by mibefradil
    • Oct;
    • Gläser S, Steinbach M, Opitz C, et al. Torsades de pointes caused by mibefradil. Eur J Heart Fail 2001 Oct; 3 (5): 627-30
    • (2001) Eur J Heart Fail , vol.3 , Issue.5 , pp. 627-630
    • Gläser, S.1    Steinbach, M.2    Opitz, C.3
  • 26
    • 0028569144 scopus 로고
    • Efonidipine hydrochloride: A new calcium antagonist
    • Masuda Y, Tanaka S. Efonidipine hydrochloride: a new calcium antagonist. Cardiovasc Drug Rev 1994; 12 (2): 123-35
    • (1994) Cardiovasc Drug Rev , vol.12 , Issue.2 , pp. 123-135
    • Masuda, Y.1    Tanaka, S.2
  • 27
    • 9544235530 scopus 로고
    • Clinical evaluation of the antihypertensive effect of NZ-105 in patients with essential hypertension
    • in Japanese
    • Yamada K, Ishii M, Mizuno Y, et al. Clinical evaluation of the antihypertensive effect of NZ-105 in patients with essential hypertension [in Japanese]. J Clin Exp Med 1992; 161: 275-92
    • (1992) J Clin Exp Med , vol.161 , pp. 275-292
    • Yamada, K.1    Ishii, M.2    Mizuno, Y.3
  • 28
    • 9244251905 scopus 로고
    • Studies on the metabolic fate of NZ-105: Absorption, distribution, metabolism and excretion after a single administration to rats
    • Shinozaki Y, Himori Y, Sano H, et al. Studies on the metabolic fate of NZ-105: absorption, distribution, metabolism and excretion after a single administration to rats. Xenobio Metabol and Dispors 1991; 6: 919-32
    • (1991) Xenobio Metabol and Dispors , vol.6 , pp. 919-932
    • Shinozaki, Y.1    Himori, Y.2    Sano, H.3
  • 29
    • 0026344868 scopus 로고
    • NZ-105, a new 1,4-dihydropyridine derivative: Correlation between dihydropyridine receptor binding and inhibition of calcium uptake in rabbit aorta
    • Nov;
    • Yamashita T, Masuda Y, Sakai T, et al. NZ-105, a new 1,4-dihydropyridine derivative: correlation between dihydropyridine receptor binding and inhibition of calcium uptake in rabbit aorta. Jpn J Pharmacol 1991 Nov; 57 (3): 337-48
    • (1991) Jpn J Pharmacol , vol.57 , Issue.3 , pp. 337-348
    • Yamashita, T.1    Masuda, Y.2    Sakai, T.3
  • 30
    • 0032557472 scopus 로고    scopus 로고
    • 2+ currents by efonidipine: Possible mechanism for its chronotropic effect
    • May 22;
    • 2+ currents by efonidipine: possible mechanism for its chronotropic effect. Eur J Pharmacol 1998 May 22; 349 (2-3): 351-7
    • (1998) Eur J Pharmacol , vol.349 , Issue.2-3 , pp. 351-357
    • Masumiya, H.1    Shijuku, T.2    Tanaka, H.3
  • 31
    • 0034623794 scopus 로고    scopus 로고
    • 2+ current by efonidipine in cardiomyocytes
    • Dec 8;
    • 2+ current by efonidipine in cardiomyocytes. Life Sci 2000 Dec 8; 68 (3): 345-51
    • (2000) Life Sci , vol.68 , Issue.3 , pp. 345-351
    • Masumiya, H.1    Kase, J.2    Tanaka, Y.3
  • 32
    • 33748673342 scopus 로고    scopus 로고
    • Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms
    • Lee TS, Kaku T, Takebayashi S, et al. Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms. Pharmacology 2006; 78 (1): 11-20
    • (2006) Pharmacology , vol.78 , Issue.1 , pp. 11-20
    • Lee, T.S.1    Kaku, T.2    Takebayashi, S.3
  • 34
    • 12444311717 scopus 로고    scopus 로고
    • The R(-)-enantiomer of efonidipine blocks T-type but not L-type calcium current in guinea pig ventricular myocardium
    • Dec;
    • Tanaka H, Komikado C, Shimada H, et al. The R(-)-enantiomer of efonidipine blocks T-type but not L-type calcium current in guinea pig ventricular myocardium. J Pharmacol Sci 2004 Dec; 96 (4): 499-501
    • (2004) J Pharmacol Sci , vol.96 , Issue.4 , pp. 499-501
    • Tanaka, H.1    Komikado, C.2    Shimada, H.3
  • 35
    • 40849085208 scopus 로고    scopus 로고
    • T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy
    • Apr;
    • Sugano N, Wakino S, Kanda T, et al. T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy. Kidney Int 2008 Apr; 73 (7): 826-34
    • (2008) Kidney Int , vol.73 , Issue.7 , pp. 826-834
    • Sugano, N.1    Wakino, S.2    Kanda, T.3
  • 36
    • 23944468017 scopus 로고    scopus 로고
    • The Japanese Trial to Assess Optimal Systolic Blood Pressure in Elderly Hypertensive Patients (JATOS): Protocol, patient characteristics, and blood pressure during the first 12 months
    • JATOS Study Group, Jun;
    • JATOS Study Group. The Japanese Trial to Assess Optimal Systolic Blood Pressure in Elderly Hypertensive Patients (JATOS): protocol, patient characteristics, and blood pressure during the first 12 months. Hypertens Res 2005 Jun; 28 (6): 513-20
    • (2005) Hypertens Res , vol.28 , Issue.6 , pp. 513-520
  • 37
    • 31744442663 scopus 로고    scopus 로고
    • Beneficial effect of T-type calcium channel blockers on endothelial function in patients with essential hypertension
    • Nov;
    • Oshima T, Ozono R, Yano Y, et al. Beneficial effect of T-type calcium channel blockers on endothelial function in patients with essential hypertension. Hypertens Res 2005 Nov; 28 (11): 889-94
    • (2005) Hypertens Res , vol.28 , Issue.11 , pp. 889-894
    • Oshima, T.1    Ozono, R.2    Yano, Y.3
  • 38
    • 0034544597 scopus 로고    scopus 로고
    • The alpha(1G)-subunit of a voltage-dependent Ca(2+) channel is localized in rat distal nephron and collecting duct
    • Dec;
    • Andreasen D, Jensen BL, Hansen PB, et al. The alpha(1G)-subunit of a voltage-dependent Ca(2+) channel is localized in rat distal nephron and collecting duct. Am J Physiol Renal Physiol 2000 Dec; 279 (6): F997-1005
    • (2000) Am J Physiol Renal Physiol , vol.279 , Issue.6
    • Andreasen, D.1    Jensen, B.L.2    Hansen, P.B.3
  • 39
    • 0035964911 scopus 로고    scopus 로고
    • Differential expression of T- and L-type voltage-dependent calcium channels in renal resistance vessels
    • Sep 28;
    • Hansen PB, Jensen BL, Andreasen D, et al. Differential expression of T- and L-type voltage-dependent calcium channels in renal resistance vessels. Circ Res 2001 Sep 28; 89 (7): 630-8
    • (2001) Circ Res , vol.89 , Issue.7 , pp. 630-638
    • Hansen, P.B.1    Jensen, B.L.2    Andreasen, D.3
  • 40
    • 0029927951 scopus 로고    scopus 로고
    • Disparate effects of calcium antagonists on renal microcirculation
    • Mar 1;
    • Hayashi K, Nagahama T, Oka K, et al. Disparate effects of calcium antagonists on renal microcirculation. Hypertens Res 1996 Mar 1; 19 (1): 31-6
    • (1996) Hypertens Res , vol.19 , Issue.1 , pp. 31-36
    • Hayashi, K.1    Nagahama, T.2    Oka, K.3
  • 41
    • 33847023386 scopus 로고    scopus 로고
    • 2+ channel subtypes and pharmacology in the kidney
    • Feb 16;
    • 2+ channel subtypes and pharmacology in the kidney. Circ Res 2007 Feb 16; 100 (3): 342-53
    • (2007) Circ Res , vol.100 , Issue.3 , pp. 342-353
    • Hayashi, K.1    Wakino, S.2    Sugano, N.3
  • 42
    • 0031922876 scopus 로고    scopus 로고
    • Renal protective effects of efonidipine in partially nephrectomized spontaneously hypertensive rats
    • Apr;
    • Fujiwara K, Kanno Y, Hayashi K, et al. Renal protective effects of efonidipine in partially nephrectomized spontaneously hypertensive rats. Clin Exp Hypertens 1998 Apr; 20 (3): 295-312
    • (1998) Clin Exp Hypertens , vol.20 , Issue.3 , pp. 295-312
    • Fujiwara, K.1    Kanno, Y.2    Hayashi, K.3
  • 43
    • 0037307604 scopus 로고    scopus 로고
    • Effect of efonidipine and ACE inhibitors on proteinuria in human hypertension with renal impairment
    • Feb;
    • Hayashi K, Kumagai H, Saruta T. Effect of efonidipine and ACE inhibitors on proteinuria in human hypertension with renal impairment. Am J Hypertens 2003 Feb; 16 (2): 116-22
    • (2003) Am J Hypertens , vol.16 , Issue.2 , pp. 116-122
    • Hayashi, K.1    Kumagai, H.2    Saruta, T.3
  • 44
    • 0043074746 scopus 로고    scopus 로고
    • Role of actions of calcium antagonists on efferent arterioles: With special references to glomerular hypertension
    • Jul-Aug;
    • Hayashi K, Ozawa Y, Fujiwara K, et al. Role of actions of calcium antagonists on efferent arterioles: with special references to glomerular hypertension. Am J Nephrol 2003 Jul-Aug; 23 (4): 229-44
    • (2003) Am J Nephrol , vol.23 , Issue.4 , pp. 229-244
    • Hayashi, K.1    Ozawa, Y.2    Fujiwara, K.3
  • 45
    • 0028183227 scopus 로고
    • 2+ channels are abnormal in genetically determined cardiomyopathic hamster hearts
    • Jul;
    • 2+ channels are abnormal in genetically determined cardiomyopathic hamster hearts. Circ Res 1994 Jul; 75 (1): 149-55
    • (1994) Circ Res , vol.75 , Issue.1 , pp. 149-155
    • Sen, L.1    Smith, T.W.2
  • 46
    • 0038517877 scopus 로고    scopus 로고
    • 2+) channels in ventricular cells from hypertrophied rat hearts
    • Sep;
    • 2+) channels in ventricular cells from hypertrophied rat hearts. J Mol Cell Cardiol 1999 Sep; 31 (9): 1617-25
    • (1999) J Mol Cell Cardiol , vol.31 , Issue.9 , pp. 1617-1625
    • Martinez, M.L.1    Heredia, M.P.2    Delgado, C.3
  • 47
    • 0027337521 scopus 로고
    • 2+ current is expressed in hypertrophied adult feline left ventricular myocytes
    • Oct;
    • 2+ current is expressed in hypertrophied adult feline left ventricular myocytes. Circ Res 1993 Oct; 73 (4): 777-82
    • (1993) Circ Res , vol.73 , Issue.4 , pp. 777-782
    • Nuss, H.B.1    Houser, S.R.2
  • 48
    • 0034912206 scopus 로고    scopus 로고
    • Effects of mibefradil, a T- and L-type calcium channel blocker, on cardiac remodeling in the UM-X7.1 cardiomyopathic hamster
    • Jan;
    • Villame J, Massicotte J, Jasmin G, et al. Effects of mibefradil, a T- and L-type calcium channel blocker, on cardiac remodeling in the UM-X7.1 cardiomyopathic hamster. Cardiovasc Drugs Ther 2001 Jan; 15 (1): 41-8
    • (2001) Cardiovasc Drugs Ther , vol.15 , Issue.1 , pp. 41-48
    • Villame, J.1    Massicotte, J.2    Jasmin, G.3
  • 49
    • 0031019537 scopus 로고    scopus 로고
    • Increased survival after long-term treatment with mibefradil, a selective T-channel calcium antagonist, in heart failure
    • Feb;
    • Mulder P, Richard V, Compagnon P, et al. Increased survival after long-term treatment with mibefradil, a selective T-channel calcium antagonist, in heart failure. J Am Coll Cardiol 1997 Feb; 29 (2): 416-21
    • (1997) J Am Coll Cardiol , vol.29 , Issue.2 , pp. 416-421
    • Mulder, P.1    Richard, V.2    Compagnon, P.3
  • 50
    • 0027257160 scopus 로고
    • Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin IIinduced hypertrophy in cultured rat cardiomyocytes
    • Jul;
    • Ito H, Hirata Y, Adachi S, et al. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin IIinduced hypertrophy in cultured rat cardiomyocytes. J Clin Invest 1993 Jul; 92 (1): 398-403
    • (1993) J Clin Invest , vol.92 , Issue.1 , pp. 398-403
    • Ito, H.1    Hirata, Y.2    Adachi, S.3
  • 51
    • 0345688039 scopus 로고    scopus 로고
    • Reinduction of T-type calcium channels by endothelin-1 in failing hearts in vivo and in adult rat ventricular myocytes in vitro
    • Nov 18;
    • Izumi T, Kihara Y, Sarai N, et al. Reinduction of T-type calcium channels by endothelin-1 in failing hearts in vivo and in adult rat ventricular myocytes in vitro. Circulation 2003 Nov 18; 108 (20): 2530-5
    • (2003) Circulation , vol.108 , Issue.20 , pp. 2530-2535
    • Izumi, T.1    Kihara, Y.2    Sarai, N.3
  • 52
    • 21744457238 scopus 로고    scopus 로고
    • Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes
    • Aug 1;
    • Lalevee N, Rebsamen MC, Barrere-Lemaire S, et al. Aldosterone increases T-type calcium channel expression and in vitro beating frequency in neonatal rat cardiomyocytes. Cardiovasc Res 2005 Aug 1; 67 (2): 216-24
    • (2005) Cardiovasc Res , vol.67 , Issue.2 , pp. 216-224
    • Lalevee, N.1    Rebsamen, M.C.2    Barrere-Lemaire, S.3
  • 53
    • 0031808487 scopus 로고    scopus 로고
    • A comparison of the effects of mibefradil and atenolol on regression of left ventricular hypertrophy in hypertensive patients
    • May;
    • Hoglund C, Cifkova R, Mimran A, et al. A comparison of the effects of mibefradil and atenolol on regression of left ventricular hypertrophy in hypertensive patients. Cardiology 1998 May; 89 (4): 263-70
    • (1998) Cardiology , vol.89 , Issue.4 , pp. 263-270
    • Hoglund, C.1    Cifkova, R.2    Mimran, A.3
  • 54
    • 0030761387 scopus 로고    scopus 로고
    • Efficacy of mibefradil compared with amlodipine in suppressing exercise-induced and daily silent ischemia: Results of a multicenter, placebo-controlled trial
    • Oct 21;
    • Tzivoni D, Kadr H, Braat S, et al. Efficacy of mibefradil compared with amlodipine in suppressing exercise-induced and daily silent ischemia: results of a multicenter, placebo-controlled trial. Circulation 1997 Oct 21; 96 (8): 2557-64
    • (1997) Circulation , vol.96 , Issue.8 , pp. 2557-2564
    • Tzivoni, D.1    Kadr, H.2    Braat, S.3
  • 55
    • 0033672215 scopus 로고    scopus 로고
    • T-type calcium currents in rat cardiomyocytes during postnatal development: Contribution to hormone secretion
    • Nov;
    • Leuranguer V, Monteil A, Bourinet E, et al. T-type calcium currents in rat cardiomyocytes during postnatal development: contribution to hormone secretion. Am J Physiol Heart Circ Physiol 2000 Nov; 279 (5): H2540-8
    • (2000) Am J Physiol Heart Circ Physiol , vol.279 , Issue.5
    • Leuranguer, V.1    Monteil, A.2    Bourinet, E.3
  • 56
    • 34447250066 scopus 로고    scopus 로고
    • Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart
    • Jul 15;
    • Gaborit N, Le Bouter S, Szuts V, et al. Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart. J Physiol 2007 Jul 15; 582 (Pt 2): 675-93
    • (2007) J Physiol , vol.582 , Issue.PART 2 , pp. 675-693
    • Gaborit, N.1    Le Bouter, S.2    Szuts, V.3
  • 57
    • 0029099346 scopus 로고    scopus 로고
    • Wijffels MC, Kirchhof CJ, Dorland R, et al. Atrial fibrillation begets atrial fibrillation: a study in awake chronically instrumented goats. Circulation 1995 Oct 1; 92 (7): 1954-68
    • Wijffels MC, Kirchhof CJ, Dorland R, et al. Atrial fibrillation begets atrial fibrillation: a study in awake chronically instrumented goats. Circulation 1995 Oct 1; 92 (7): 1954-68
  • 58
    • 0033574615 scopus 로고    scopus 로고
    • Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation
    • Apr 16;
    • Yue L, Melnyk P, Gaspo R, et al. Molecular mechanisms underlying ionic remodeling in a dog model of atrial fibrillation. Circ Res 1999 Apr 16; 84 (7): 776-84
    • (1999) Circ Res , vol.84 , Issue.7 , pp. 776-784
    • Yue, L.1    Melnyk, P.2    Gaspo, R.3
  • 59
    • 0030765569 scopus 로고    scopus 로고
    • Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation
    • Oct;
    • Yue L, Feng J, Gaspo R, et al. Ionic remodeling underlying action potential changes in a canine model of atrial fibrillation. Circ Res 1997 Oct; 81 (4): 512-25
    • (1997) Circ Res , vol.81 , Issue.4 , pp. 512-525
    • Yue, L.1    Feng, J.2    Gaspo, R.3
  • 60
    • 0035110217 scopus 로고    scopus 로고
    • Intracellular calcium changes and tachycardia-induced contractile dysfunction in canine atrial myocytes
    • Mar;
    • Sun H, Chartier D, Leblanc N, et al. Intracellular calcium changes and tachycardia-induced contractile dysfunction in canine atrial myocytes. Cardiovasc Res 2001 Mar; 49 (4): 751-61
    • (2001) Cardiovasc Res , vol.49 , Issue.4 , pp. 751-761
    • Sun, H.1    Chartier, D.2    Leblanc, N.3
  • 61
    • 0030953869 scopus 로고    scopus 로고
    • Tieleman RG, De Langen C, Van Gelder IC, et al. Verapamil reduces tachycardia-induced electrical remodeling of the atria. Circulation 1997 Apr 1; 95 (7): 1945-53
    • Tieleman RG, De Langen C, Van Gelder IC, et al. Verapamil reduces tachycardia-induced electrical remodeling of the atria. Circulation 1997 Apr 1; 95 (7): 1945-53
  • 62
    • 0035312785 scopus 로고    scopus 로고
    • Increased dispersion and shortened refractoriness caused by verapamil in chronic atrial fibrillation
    • Apr;
    • Ramanna H, Elvan A, Wittkampf FH, et al. Increased dispersion and shortened refractoriness caused by verapamil in chronic atrial fibrillation. J Am Coll Cardiol 2001 Apr; 37 (5): 1403-7
    • (2001) J Am Coll Cardiol , vol.37 , Issue.5 , pp. 1403-1407
    • Ramanna, H.1    Elvan, A.2    Wittkampf, F.H.3
  • 63
    • 0033962885 scopus 로고    scopus 로고
    • Effect of verapamil on long-term tachycardia-induced atrial electrical remodeling
    • Jan 18;
    • Lee SH, Yu WC, Cheng JJ, et al. Effect of verapamil on long-term tachycardia-induced atrial electrical remodeling. Circulation 2000 Jan 18; 101 (2): 200-6
    • (2000) Circulation , vol.101 , Issue.2 , pp. 200-206
    • Lee, S.H.1    Yu, W.C.2    Cheng, J.J.3
  • 64
    • 0345440145 scopus 로고    scopus 로고
    • 2+ channel blocker mibefradil prevents the development of a substrate for atrial fibrillation by tachycardia-induced atrial remodeling in dogs. Circulation 1999Nov 23; 100 (21): 2191-7
    • 2+ channel blocker mibefradil prevents the development of a substrate for atrial fibrillation by tachycardia-induced atrial remodeling in dogs. Circulation 1999Nov 23; 100 (21): 2191-7
  • 65
    • 0035113546 scopus 로고    scopus 로고
    • Differential efficacy of L- and T-type calcium channel blockers in preventing tachycardia-induced atrial remodeling in dogs
    • Mar;
    • Fareh S, Benardeau A, Nattel S. Differential efficacy of L- and T-type calcium channel blockers in preventing tachycardia-induced atrial remodeling in dogs. Cardiovasc Res 2001 Mar; 49 (4): 762-70
    • (2001) Cardiovasc Res , vol.49 , Issue.4 , pp. 762-770
    • Fareh, S.1    Benardeau, A.2    Nattel, S.3
  • 66
    • 4344585665 scopus 로고    scopus 로고
    • A comparison between calcium channel blocking drugs with different potencies for T- and L-type channels in preventing atrial electrical remodeling
    • Sep;
    • Ohashi N, Mitamura H, Tanimoto K, et al. A comparison between calcium channel blocking drugs with different potencies for T- and L-type channels in preventing atrial electrical remodeling. J Cardiovasc Pharmacol 2004 Sep; 44 (3): 386-92
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.3 , pp. 386-392
    • Ohashi, N.1    Mitamura, H.2    Tanimoto, K.3
  • 67
    • 2442519246 scopus 로고    scopus 로고
    • T-type calcium current in electrical activity of cardiomyocytes isolated from rabbit pulmonary vein
    • May;
    • Chen YC, Chen SA, Chen YJ, et al. T-type calcium current in electrical activity of cardiomyocytes isolated from rabbit pulmonary vein. J Cardiovasc Electrophysiol 2004 May; 15 (5): 567-71
    • (2004) J Cardiovasc Electrophysiol , vol.15 , Issue.5 , pp. 567-571
    • Chen, Y.C.1    Chen, S.A.2    Chen, Y.J.3
  • 68
    • 33645807633 scopus 로고    scopus 로고
    • Short- and long-term amiodarone treatments regulate Cav3.2 low-voltage-activated T-type Ca2+ channel through distinct mechanisms
    • May;
    • Yamashita N, Kaku T, Uchino T, et al. Short- and long-term amiodarone treatments regulate Cav3.2 low-voltage-activated T-type Ca2+ channel through distinct mechanisms. Mol Pharmacol 2006 May; 69 (5):1684-91
    • (2006) Mol Pharmacol , vol.69 , Issue.5 , pp. 1684-1691
    • Yamashita, N.1    Kaku, T.2    Uchino, T.3
  • 69
    • 0037453022 scopus 로고    scopus 로고
    • Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium: Insights into the mechanism of the superior efficacy of amiodarone
    • Mar 18;
    • Shinagawa K, Shiroshita-Takeshita A, Schram G, et al. Effects of antiarrhythmic drugs on fibrillation in the remodeled atrium: insights into the mechanism of the superior efficacy of amiodarone. Circulation 2003 Mar 18; 107 (10): 1440-6
    • (2003) Circulation , vol.107 , Issue.10 , pp. 1440-1446
    • Shinagawa, K.1    Shiroshita-Takeshita, A.2    Schram, G.3
  • 70
    • 0026706518 scopus 로고
    • Block of T-type Ca channels in guinea pig atrial cells by antiarrhythmic agents and Ca channel antagonists
    • Oct;
    • Cohen CJ, Spires S, Van Skiver D. Block of T-type Ca channels in guinea pig atrial cells by antiarrhythmic agents and Ca channel antagonists. J Gen Physiol 1992 Oct; 100 (4): 703-28
    • (1992) J Gen Physiol , vol.100 , Issue.4 , pp. 703-728
    • Cohen, C.J.1    Spires, S.2    Van Skiver, D.3
  • 71
    • 0042063790 scopus 로고    scopus 로고
    • Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm
    • Aug 15;
    • Fujiki A, Tsuneda T, Sugao M, et al. Usefulness and safety of bepridil in converting persistent atrial fibrillation to sinus rhythm. Am J Cardiol 2003 Aug 15; 92 (4): 472-5
    • (2003) Am J Cardiol , vol.92 , Issue.4 , pp. 472-475
    • Fujiki, A.1    Tsuneda, T.2    Sugao, M.3
  • 72
    • 31644451515 scopus 로고    scopus 로고
    • Bepridil inhibits subacute phase of atrial electrical remodeling in canine rapid atrial stimulation model
    • Feb;
    • Sato D, Niwano S, Imaki R, et al. Bepridil inhibits subacute phase of atrial electrical remodeling in canine rapid atrial stimulation model. Circ J 2006 Feb; 70 (2): 206-13
    • (2006) Circ J , vol.70 , Issue.2 , pp. 206-213
    • Sato, D.1    Niwano, S.2    Imaki, R.3
  • 73
    • 22544482335 scopus 로고    scopus 로고
    • Voltage-dependent and frequency-independent inhibition of recombinant Cav3.2 T-type Ca2+ channel by bepridil
    • Jul;
    • Uchino T, Lee TS, Kaku T, et al. Voltage-dependent and frequency-independent inhibition of recombinant Cav3.2 T-type Ca2+ channel by bepridil. Pharmacology 2005 Jul; 74 (4): 174-81
    • (2005) Pharmacology , vol.74 , Issue.4 , pp. 174-181
    • Uchino, T.1    Lee, T.S.2    Kaku, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.