The Japanese trial to assess optimal systolic blood pressure in elderly hypertensive patients (JATOS): Protocol, patient characteristics, and blood pressure during the first 12 months

Hypertension Research

Volumn 28, Issue 6, 2005, Pages 513-520

  Goto, Yoshio ^a   Ishii, Masao ^b   Saruta, Takao ^a   Kawakami, Tadashi ^a   Kawabe, Kanemi ^a   Ogihara, Toshio ^a   Kawano, Yuhei ^a   Kikuchi, Kenjiro ^a   Shimamoto, Kazuaki ^a   Sakurai, Masayuki ^a   Sugahara, Makoto ^a   Ito, Sadayoshi ^a   Matsuoka, Hiroaki ^a   Sato, Yoshihiko ^a   Ono, Seishiro ^a   Umemura, Satoshi ^a   Shiota, Yoshiro ^a   Miyagawa, Masaaki ^a   Doniwa, Kenichi ^a   Kimura, Genjiro ^a   Tada, Yutaka ^a   Nakao, Masayoshi ^a   Takami, Takeshi ^a   Arita, Mikio ^a   Okamoto, Mitunori ^a   Hiwada, Kunio ^a   Matsuzaki, Masunori ^a   Takeshita, Akira ^a   Abe, Kozaburo ^a   Honda, Takashi ^a   Minakoe, Shinichi ^a   Fujishima, Masanori ^a   Kitabatake, Akira ^a   Hayashi, Koichi ^a   Yoshikawa, Junichi ^a   Harada, Kazuhiro ^a   Shimizu, Naokata ^a   Hirotsu, Chihiro ^a   Tsubaki, Hiroe ^a   Nagai, Ryozo ^a   Kuwajima, Iwao ^a   Adachi, Machiko ^a   Takeuchi, Keiko ^a   Shibagaki, Hideo ^a   Iwakura, Satoshi ^c   Matsubara, Yoshihiro ^c   Tasaki, Takenobu ^c   Tsuchiya, Yoshihide ^c   Hida, Hideaki ^c   Mori, Kenzo ^c   Yazaki, Yoshio ^a   more..

^a Yokohama Seamen's Insurance Hospital ^*

^b Yokohama Seamen's Insurance Hospital   (Japan)

^c SHIONOGI AND CO LTD   (Japan)

Author keywords

Calcium antagonists; Efonidipine hydrochloride; Essential hypertension; Systolic blood pressure

Indexed keywords

CALCIUM ANTAGONIST; EFONIDIPINE;

AGE DISTRIBUTION; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CARDIOVASCULAR RISK; CAUSE OF DEATH; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; GERIATRIC PATIENT; HEART DISEASE; HEART INFARCTION; HUMAN; HYPERTENSION; JAPAN; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; PATIENT CARE; PERIPHERAL OCCLUSIVE ARTERY DISEASE; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; STROKE; SYSTOLIC BLOOD PRESSURE; VASCULAR DISEASE;

EID: 23944468017     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.28.513     Document Type: Article

References (33)

1. National High Blood Pressure Education Program Working Group: National High Blood Pressure Education Program Working Group report on hypertension in the elderly. Hypertension 1993; 23: 275-285.
2. Fields LE, Burt VL, Cutler JA, Hughes J, Rocella EJ, Sorlie P: The burden of adult hypertension in the United States 1999-2000. A rising tide. Hypertension 2004; 44: 398-404.
3. Burt VL, Whelton P, Roccella EJ, et al: Prevention of hypertension in the US adult population: results from the Third National Health and Nutrition Examination Survey, 1988-1991. Hypertension 1995; 25: 305-313.
4. Franklin SS, Larson MG, Khan SA, et al: Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study. Circulation 2001; 103: 1245-1249.
5. Chobanian AV, Bakris GL, Black HR, et al: The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The JNC 7 report. JAMA 2003; 289: 2560-2572.
6. Guidelines Subcommittee: 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21: 1011-1053.
7. World Health Organization, International Society of Hypertension Writing Group: World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens 2003; 21: 1922-1983.
8. SHEP Cooperative Research Group: Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 1991; 265: 3255-3264.
9. Staessen JA, Fagard R, Thijs L, et al: Randomized double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 1997; 350: 757-764.
10. Izzo JL, Levy D, Black HR: Importance of systolic blood pressure in older Americans. Hypertension 2000; 35: 1021-1024.
11. August P: Initial treatment of hypertension. N Engl J Med 2003; 348: 610-617.
12. Hansson L, Zanchetti A, Carruthers SG, et al: Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet 1998; 351: 1755-1762.
13. Port S, Demer L, Jennrich R, Walter D, Garfinkel A: Systolic blood pressure and mortality. Lancet 2000; 355: 175-180.
14. Ogihara T, Hiwada K, Morimoto S, et al: Guidelines for treatment of hypertension in the elderly - 2002 revised version -. Hypertens Res 2003; 26: 1-36.
15. Hansson L, Hedner T, Dahlöf B: Prospective randomized open blinded end-point (PROBE) study: a novel design for intervention trials. Blood Pressure 1992; 1: 113-119.
16. Sakoda R, Kamikawaji Y, Seto K: Synthesis of 1,4-dihydropyridine-5-phosphonates and their calcium-antagonistic and antihypertensive activities: novel calcium-antagonist 2-[benzyl(phenyl)amino]ethyl 5-(5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinan-2-yl) -1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylate hydrochloride ethanol (NZ-105) and its crystal structure. Chem Pharm Bull 1992; 40: 2362-2369.
17. Yamada K, Ishii M, Mizuno Y, Nakajima M, Ohashi Y: Clinical evaluation of the antihypertensive effect of NZ-105 in patients with essential hypertension: double-blind comparison between NZ-105 and nicardipine hydrochloride retard. J Clin Exp Med (Igaku No Ayumi) 1992; 161: 275-292 (in Japanese).
18. Japan Diabetes Society: Guide for the Treatment of Diabetes Mellitus. Tokyo, Bunkodo, 1999 (in Japanese).
19. Hata Y, Mabuchi H, Saito Y, et al: Report of the Japan Atherosclerosis Society (JAS) guidelines for diagnosis and treatment of hyperlipidemia in Japanese adults. J Atheroscler Thromb 2002; 9: 1-27.
20. Research Division, Nissan Chemical Industries, Ltd: A Summary of Post-Marketing Surveillance Data for Efonidipine Hydrochloride 10 mg Tablets, 20 mg Tablets, and 40 ing Tablets. Tokyo, Nissan Chemical Industries, Ltd, 2000 (in Japanese).
21. Sato T: Sample sizes for survival analysis based on the conditional score test for person-time observation. Jpn J Biometrics 2002; 23: 27-35.
22. Saito K, Kodama Y, Ono S, Fujimura A: Recent changes in quality in Japanese clinical trials. Ann Pharmacother 2004; 38: 151-155.
23. Muratani H, Fukiyama K, Kamiyama T, et al: Current status of antihypertensive therapy for elderly patients in Japan. Hypertens Res 1996; 19: 281-290.
24. Hyman DJ, Pavlik VK: Uncontrolled hypertension as a risk for coronary artery disease: patient characteristics and the role of physician intervention. Curr Atheroscler Res 2003; 5: 131-138.
25. Uemura K, Piša Z: Trends in cardiovascular disease mortality in industrialized countries since 1950. World Health Stat Q 1988; 41: 155-178.
26. Ueda K, Omae T, Hasuo Y, et al: Prognosis and outcome of elderly hypertensives in a Japanese community: results from a long-term prospective study. J Hypertens 1988; 6: 991-997.
27. Kimura Y, Takishita S, Muratani H, et al: Demographic study of first-ever stroke and acute myocardial infarction in Okinawa, Japan. Intern Med 1998; 37: 736-745.
28. National Intervention Cooperative Study in Elderly Hypertensive Study Group: Randomized double-blind comparison of a calcium antagonist and a diuretic in elderly hypertensives. Hypertension 1999; 34: 1129-1133.
29. Liu L, Wang JG, Gong L, Liu G, Staessen JA, for the Systolic Hypertension in China (Syst-China) Collaborative Group: Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension. J Hypertens 1998; 16: 1823-1829.
30. Brown MJ, Palmer CR, Castaigne A, et al: Morbidity and mortality in patients with randomised to double-blind treatment with a long-acting calcium channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). Lancet 2000; 356: 366-372.
31. Hansson L, Hedner T, Lund-Johansen P, et al: Randomised trial of effects of calcium antagonists compared with diuretics and β-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study. Lancet 2000; 356: 359-365.
32. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group: Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. JAMA 2002; 288: 2981-2997.
33. Julius S, Kjeldsen SE, Weber M, et al, for the VALUE Trial Group: Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004; 363: 2022-2031.