메뉴 건너뛰기




Volumn 453, Issue C, 2009, Pages 397-416

Chapter 20 Analyzing Macroautophagy in Hepatocytes and the Liver

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CELL INTERACTION; CELL ISOLATION; ELECTRON MICROSCOPY; IMMUNOBLOTTING; LIVER CELL; LIVER CELL CULTURE; LIVER DISEASE; LIVER HISTOLOGY; LIVER MITOCHONDRION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN METABOLISM; PROTEIN SYNTHESIS; PROTEOMICS; REVIEW; WESTERN BLOTTING; ANIMAL; ARTICLE; CELL CULTURE; LIVER; METABOLISM; MOUSE; PHYSIOLOGY; ULTRASTRUCTURE;

EID: 59649125309     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(08)04020-2     Document Type: Review
Times cited : (7)

References (47)
  • 2
    • 27944504351 scopus 로고    scopus 로고
    • p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy G., Lamark T., Brech A., Outzen H., Perander M., Overvatn A., Stenmark H., and Johansen T. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 171 (2005) 603-614
    • (2005) J. Cell Biol. , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6    Stenmark, H.7    Johansen, T.8
  • 3
    • 0028899789 scopus 로고
    • Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
    • Blommaart E.F., Luiken J.J., Blommaart P.J., van Woerkom G.M., and Meijer A.J. Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270 (1995) 2320-2326
    • (1995) J. Biol. Chem. , vol.270 , pp. 2320-2326
    • Blommaart, E.F.1    Luiken, J.J.2    Blommaart, P.J.3    van Woerkom, G.M.4    Meijer, A.J.5
  • 4
    • 38149098485 scopus 로고    scopus 로고
    • Developmental expression of LC3alpha and beta: Absence of fibronectin or autophagy phenotype in LC3beta knockout mice
    • Cann G.M., Guignabert C., Ying L., Deshpande N., Bekker J.M., Wang L., Zhou B., and Rabinovitch M. Developmental expression of LC3alpha and beta: Absence of fibronectin or autophagy phenotype in LC3beta knockout mice. Dev. Dyn. 237 (2008) 187-195
    • (2008) Dev. Dyn. , vol.237 , pp. 187-195
    • Cann, G.M.1    Guignabert, C.2    Ying, L.3    Deshpande, N.4    Bekker, J.M.5    Wang, L.6    Zhou, B.7    Rabinovitch, M.8
  • 5
    • 0014083718 scopus 로고
    • Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes
    • Deter R.L., and De Duve C. Influence of glucagon, an inducer of cellular autophagy, on some physical properties of rat liver lysosomes. J. Cell Biol. 33 (1967) 437-449
    • (1967) J. Cell Biol. , vol.33 , pp. 437-449
    • Deter, R.L.1    De Duve, C.2
  • 6
    • 4043131033 scopus 로고    scopus 로고
    • Bid-dependent generation of oxygen radicals promotes death receptor activation-induced apoptosis in murine hepatocytes
    • Ding W.X., Ni H.M., DiFrancesca D., Stolz D.B., and Yin X.M. Bid-dependent generation of oxygen radicals promotes death receptor activation-induced apoptosis in murine hepatocytes. Hepatology 40 (2004) 403-413
    • (2004) Hepatology , vol.40 , pp. 403-413
    • Ding, W.X.1    Ni, H.M.2    DiFrancesca, D.3    Stolz, D.B.4    Yin, X.M.5
  • 7
    • 0035487007 scopus 로고    scopus 로고
    • The mitochondrial permeability transition initiates autophagy in rat hepatocytes
    • Elmore S.P., Qian T., Grissom S.F., and Lemasters J.J. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. Faseb J. 15 (2001) 2286-2287
    • (2001) Faseb J. , vol.15 , pp. 2286-2287
    • Elmore, S.P.1    Qian, T.2    Grissom, S.F.3    Lemasters, J.J.4
  • 8
    • 0028856914 scopus 로고
    • Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: Effects of vinblastine and asparagine on vacuole distributions
    • Fengsrud M., Roos N., Berg T., Liou W., Slot J.W., and Seglen P.O. Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: Effects of vinblastine and asparagine on vacuole distributions. Exp. Cell Res. 221 (1995) 504-519
    • (1995) Exp. Cell Res. , vol.221 , pp. 504-519
    • Fengsrud, M.1    Roos, N.2    Berg, T.3    Liou, W.4    Slot, J.W.5    Seglen, P.O.6
  • 11
    • 33646204392 scopus 로고    scopus 로고
    • Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size
    • Hosokawa N., Hara Y., and Mizushima N. Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size. FEBS Lett. 580 (2006) 2623-2629
    • (2006) FEBS Lett. , vol.580 , pp. 2623-2629
    • Hosokawa, N.1    Hara, Y.2    Mizushima, N.3
  • 12
    • 33645905712 scopus 로고    scopus 로고
    • Autophagy, mitochondrial quality control, and oncogenesis
    • Jin S. Autophagy, mitochondrial quality control, and oncogenesis. Autophagy 2 (2006) 80-84
    • (2006) Autophagy , vol.2 , pp. 80-84
    • Jin, S.1
  • 15
    • 1342309013 scopus 로고    scopus 로고
    • Hydrodynamic delivery of DNA
    • Knapp J.E., and Liu D. Hydrodynamic delivery of DNA. Methods Mol. Biol. 245 (2004) 245-250
    • (2004) Methods Mol. Biol. , vol.245 , pp. 245-250
    • Knapp, J.E.1    Liu, D.2
  • 17
    • 0020040519 scopus 로고
    • Accumulation of autophagosomes after inhibition of hepatocytic protein degradation by vinblastine, leupeptin or a lysosomotropic amine
    • Kovacs A.L., Reith A., and Seglen P.O. Accumulation of autophagosomes after inhibition of hepatocytic protein degradation by vinblastine, leupeptin or a lysosomotropic amine. Exp. Cell Res. 137 (1982) 191-201
    • (1982) Exp. Cell Res. , vol.137 , pp. 191-201
    • Kovacs, A.L.1    Reith, A.2    Seglen, P.O.3
  • 18
    • 33645451010 scopus 로고    scopus 로고
    • Mutant fibrinogen cleared from the endoplasmic reticulum via endoplasmic reticulum-associated protein degradation and autophagy: An explanation for liver disease
    • quiz 1404-1405
    • Kruse K.B., Dear A., Kaltenbrun E.R., Crum B.E., George P.M., Brennan S.O., and McCracken A.A. Mutant fibrinogen cleared from the endoplasmic reticulum via endoplasmic reticulum-associated protein degradation and autophagy: An explanation for liver disease. Am. J. Pathol. 168 (2006) 1299-1308 quiz 1404-1405
    • (2006) Am. J. Pathol. , vol.168 , pp. 1299-1308
    • Kruse, K.B.1    Dear, A.2    Kaltenbrun, E.R.3    Crum, B.E.4    George, P.M.5    Brennan, S.O.6    McCracken, A.A.7
  • 19
    • 36348968763 scopus 로고    scopus 로고
    • Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies
    • Ku N.O., Strnad P., Zhong B.H., Tao G.Z., and Omary M.B. Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies. Hepatology 46 (2007) 1639-1649
    • (2007) Hepatology , vol.46 , pp. 1639-1649
    • Ku, N.O.1    Strnad, P.2    Zhong, B.H.3    Tao, G.Z.4    Omary, M.B.5
  • 21
    • 51649124519 scopus 로고    scopus 로고
    • Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation
    • Kundu M., Lindsten T., Yang C.Y., Wu J., Zhao F., Zhang J., Selak M.A., Ney P.A., and Thompson C.B. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood 112 (2008) 1493-1502
    • (2008) Blood , vol.112 , pp. 1493-1502
    • Kundu, M.1    Lindsten, T.2    Yang, C.Y.3    Wu, J.4    Zhao, F.5    Zhang, J.6    Selak, M.A.7    Ney, P.A.8    Thompson, C.B.9
  • 22
    • 34547132328 scopus 로고    scopus 로고
    • Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
    • Marino G., Salvador-Montoliu N., Fueyo A., Knecht E., Mizushima N., and Lopez-Otin C. Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J. Biol. Chem. 282 (2007) 18573-18583
    • (2007) J. Biol. Chem. , vol.282 , pp. 18573-18583
    • Marino, G.1    Salvador-Montoliu, N.2    Fueyo, A.3    Knecht, E.4    Mizushima, N.5    Lopez-Otin, C.6
  • 24
    • 34248593475 scopus 로고    scopus 로고
    • AMP-activated protein kinase and autophagy
    • Meijer A.J., and Codogno P. AMP-activated protein kinase and autophagy. Autophagy 3 (2007) 238-240
    • (2007) Autophagy , vol.3 , pp. 238-240
    • Meijer, A.J.1    Codogno, P.2
  • 25
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N., Yamamoto A., Matsui M., Yoshimori T., and Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol. Biol. Cell 15 (2004) 1101-1111
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 26
    • 0014939582 scopus 로고
    • Inhibition by insulin of valine turnover in liver. Evidence for a general control of proteolysis
    • Mortimore G.E., and Mondon C.E. Inhibition by insulin of valine turnover in liver. Evidence for a general control of proteolysis. J. Biol. Chem. 245 (1970) 2375-2383
    • (1970) J. Biol. Chem. , vol.245 , pp. 2375-2383
    • Mortimore, G.E.1    Mondon, C.E.2
  • 27
    • 0023065242 scopus 로고
    • Intracellular protein catabolism and its control during nutrient deprivation and supply
    • Mortimore G.E., and Poso A.R. Intracellular protein catabolism and its control during nutrient deprivation and supply. Annu. Rev. Nutr. 7 (1987) 539-564
    • (1987) Annu. Rev. Nutr. , vol.7 , pp. 539-564
    • Mortimore, G.E.1    Poso, A.R.2
  • 28
  • 29
    • 0017697151 scopus 로고
    • Induction of autophagy by amino-acid deprivation in perfused rat liver
    • Mortimore G.E., and Schworer C.M. Induction of autophagy by amino-acid deprivation in perfused rat liver. Nature 270 (1977) 174-176
    • (1977) Nature , vol.270 , pp. 174-176
    • Mortimore, G.E.1    Schworer, C.M.2
  • 30
    • 0015500963 scopus 로고
    • Compartmentation of free valine and its relation to protein turnover in perfused rat liver
    • Mortimore G.E., Woodside K.H., and Henry J.E. Compartmentation of free valine and its relation to protein turnover in perfused rat liver. J. Biol. Chem. 247 (1972) 2776-2784
    • (1972) J. Biol. Chem. , vol.247 , pp. 2776-2784
    • Mortimore, G.E.1    Woodside, K.H.2    Henry, J.E.3
  • 31
    • 34250828455 scopus 로고    scopus 로고
    • Proteomic analysis of membrane-associated proteins from rat liver autophagosomes
    • Overbye A., Fengsrud M., and Seglen P.O. Proteomic analysis of membrane-associated proteins from rat liver autophagosomes. Autophagy 3 (2007) 300-322
    • (2007) Autophagy , vol.3 , pp. 300-322
    • Overbye, A.1    Fengsrud, M.2    Seglen, P.O.3
  • 32
    • 33748419472 scopus 로고    scopus 로고
    • The role of autophagy in alpha-1-antitrypsin deficiency: A specific cellular response in genetic diseases associated with aggregation-prone proteins
    • Perlmutter D.H. The role of autophagy in alpha-1-antitrypsin deficiency: A specific cellular response in genetic diseases associated with aggregation-prone proteins. Autophagy 2 (2006) 258-263
    • (2006) Autophagy , vol.2 , pp. 258-263
    • Perlmutter, D.H.1
  • 33
    • 0017816161 scopus 로고
    • Inhibition by insulin of the formation of autophagic vacuoles in rat liver. A morphometric approach to the kinetics of intracellular degradation by autophagy
    • Pfeifer U. Inhibition by insulin of the formation of autophagic vacuoles in rat liver. A morphometric approach to the kinetics of intracellular degradation by autophagy. J. Cell Biol. 78 (1978) 152-167
    • (1978) J. Cell Biol. , vol.78 , pp. 152-167
    • Pfeifer, U.1
  • 37
    • 48249111779 scopus 로고    scopus 로고
    • The role of autophagy in neonatal tissues: Just a response to amino acid starvation?
    • Schiaffino S., Mammucari C., and Sandri M. The role of autophagy in neonatal tissues: Just a response to amino acid starvation?. Autophagy 4 (2008) 727-730
    • (2008) Autophagy , vol.4 , pp. 727-730
    • Schiaffino, S.1    Mammucari, C.2    Sandri, M.3
  • 39
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen P.O. Preparation of isolated rat liver cells. Methods Cell Biol. 13 (1976) 29-83
    • (1976) Methods Cell Biol. , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 40
    • 0005677775 scopus 로고
    • 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • Seglen P.O., and Gordon P.B. 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Natl. Acad. Sci. USA 79 (1982) 1889-1892
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 1889-1892
    • Seglen, P.O.1    Gordon, P.B.2
  • 41
    • 0018763480 scopus 로고
    • Inhibition of the lysosomal pathway of protein degradation in isolated rat hepatocytes by ammonia, methylamine, chloroquine and leupeptin
    • Seglen P.O., Grinde B., and Solheim A.E. Inhibition of the lysosomal pathway of protein degradation in isolated rat hepatocytes by ammonia, methylamine, chloroquine and leupeptin. Eur. J. Biochem. 95 (1979) 215-225
    • (1979) Eur. J. Biochem. , vol.95 , pp. 215-225
    • Seglen, P.O.1    Grinde, B.2    Solheim, A.E.3
  • 42
    • 0032532323 scopus 로고    scopus 로고
    • Purification and characterization of autophagosomes from rat hepatocytes
    • Stromhaug P.E., Berg T.O., Fengsrud M., and Seglen P.O. Purification and characterization of autophagosomes from rat hepatocytes. Biochem. J. 335 Pt 2 (1998) 217-224
    • (1998) Biochem. J. , vol.335 , Issue.PART 2 , pp. 217-224
    • Stromhaug, P.E.1    Berg, T.O.2    Fengsrud, M.3    Seglen, P.O.4
  • 44
    • 0015523795 scopus 로고
    • Suppression of protein turnover by amino acids in the perfused rat liver
    • Woodside K.H., and Mortimore G.E. Suppression of protein turnover by amino acids in the perfused rat liver. J. Biol. Chem. 247 (1972) 6474-6481
    • (1972) J. Biol. Chem. , vol.247 , pp. 6474-6481
    • Woodside, K.H.1    Mortimore, G.E.2
  • 45
    • 43949123866 scopus 로고    scopus 로고
    • Autophagy in the liver
    • Yin X.M., Ding W.X., and Gao W. Autophagy in the liver. Hepatology 47 (2008) 1773-1785
    • (2008) Hepatology , vol.47 , pp. 1773-1785
    • Yin, X.M.1    Ding, W.X.2    Gao, W.3
  • 46
    • 33947372556 scopus 로고    scopus 로고
    • Regulation of neuronal autophagy in axon: Implication of autophagy in axonal function and dysfunction/degeneration
    • Yue Z. Regulation of neuronal autophagy in axon: Implication of autophagy in axonal function and dysfunction/degeneration. Autophagy 3 (2007) 139-141
    • (2007) Autophagy , vol.3 , pp. 139-141
    • Yue, Z.1
  • 47
    • 0042324618 scopus 로고    scopus 로고
    • Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement
    • Zhao Y., Ding W.X., Qian T., Watkins S., Lemasters J.J., and Yin X.M. Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement. Gastroenterology 125 (2003) 854-867
    • (2003) Gastroenterology , vol.125 , pp. 854-867
    • Zhao, Y.1    Ding, W.X.2    Qian, T.3    Watkins, S.4    Lemasters, J.J.5    Yin, X.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.