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Volumn 16, Issue 2, 2009, Pages 163-171

Generation of immune responses against hepatitis C virus by dendritic cells containing NS5 protein-coated microparticles

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD4 ANTIGEN; CD40 ANTIBODY; FLT3 LIGAND; GAMMA INTERFERON; INTERLEUKIN 2; LIPOPOLYSACCHARIDE; NONSTRUCTURAL PROTEIN 5; UNCLASSIFIED DRUG;

EID: 59649121584     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00287-08     Document Type: Article
Times cited : (17)

References (52)
  • 1
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Albert, M. L., B. Sauter, and N. Bhardwaj. 1998. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392:86-89.
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 2
    • 0035874506 scopus 로고    scopus 로고
    • Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection
    • Auffermann-Gretzinger, S., E. B. Keeffe, and S. Levy. 2001. Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection. Blood 97:3171-3176.
    • (2001) Blood , vol.97 , pp. 3171-3176
    • Auffermann-Gretzinger, S.1    Keeffe, E.B.2    Levy, S.3
  • 3
    • 0035121503 scopus 로고    scopus 로고
    • Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection
    • Bain, C., A. Fatmi, F. Zoulim, J. P. Zarski, C. Trepo, and G. Inchauspe. 2001. Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. Gastroenterology 120:512-524.
    • (2001) Gastroenterology , vol.120 , pp. 512-524
    • Bain, C.1    Fatmi, A.2    Zoulim, F.3    Zarski, J.P.4    Trepo, C.5    Inchauspe, G.6
  • 4
    • 0034985916 scopus 로고    scopus 로고
    • Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection
    • Bassett, S. E., B. Guerra, K. Brasky, E. Miskovsky, M. Houghton, G. R. Klimpel, and R. E. Lanford. 2001. Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection. Hepatology 33:1479-1487.
    • (2001) Hepatology , vol.33 , pp. 1479-1487
    • Bassett, S.E.1    Guerra, B.2    Brasky, K.3    Miskovsky, E.4    Houghton, M.5    Klimpel, G.R.6    Lanford, R.E.7
  • 5
    • 0036162436 scopus 로고    scopus 로고
    • The molecular architecture of the TNF superfamily
    • Bodmer, J. L., P. Schneider, and J. Tschopp. 2002. The molecular architecture of the TNF superfamily. Trends Biochem. Sci. 27:19-26.
    • (2002) Trends Biochem. Sci , vol.27 , pp. 19-26
    • Bodmer, J.L.1    Schneider, P.2    Tschopp, J.3
  • 6
    • 0035192083 scopus 로고    scopus 로고
    • Different hepatitis C virus nonstruc-tural protein 3 (Ns3)-DNA-expressing vaccines induce in HLA-A2.1 transgenic mice stable cytotoxic T lymphocytes that target one major epitope
    • Brinster, C., S. Muguet, Y. C. Lone, D. Boucreux, N. Renard, A. Fournillier, F. Lemonnier, and G. Inchauspe. 2001. Different hepatitis C virus nonstruc-tural protein 3 (Ns3)-DNA-expressing vaccines induce in HLA-A2.1 transgenic mice stable cytotoxic T lymphocytes that target one major epitope. Hepatology 34:1206-1217.
    • (2001) Hepatology , vol.34 , pp. 1206-1217
    • Brinster, C.1    Muguet, S.2    Lone, Y.C.3    Boucreux, D.4    Renard, N.5    Fournillier, A.6    Lemonnier, F.7    Inchauspe, G.8
  • 7
    • 34548605445 scopus 로고    scopus 로고
    • Two modes of ligand recognition by TLRs
    • Brodsky, I., and R. Medzhitov. 2007. Two modes of ligand recognition by TLRs. Cell 130:979-981.
    • (2007) Cell , vol.130 , pp. 979-981
    • Brodsky, I.1    Medzhitov, R.2
  • 8
    • 0029811734 scopus 로고    scopus 로고
    • Progressive loss of CD8 + T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells
    • Cardin, R. D., J. W. Brooks, S. R. Sarawar, and P. C. Doherty. 1996. Progressive loss of CD8 + T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells. J. Exp. Med. 184:863-871.
    • (1996) J. Exp. Med , vol.184 , pp. 863-871
    • Cardin, R.D.1    Brooks, J.W.2    Sarawar, S.R.3    Doherty, P.C.4
  • 9
    • 0029812593 scopus 로고    scopus 로고
    • Ligation of CD40 on dendritic cells triggers production of highlevels ofinterleukin-12and enhances Tcellstimulatorycapacity:T-T help via APC activation
    • Cella, M., D. Scheidegger, K. Palmer-Lehmann, P. Lane, A. Lanzavecchia, and G. Alber. 1996. Ligation of CD40 on dendritic cells triggers production of highlevels ofinterleukin-12and enhances Tcellstimulatorycapacity:T-T help via APC activation. J. Exp. Med. 184:747-752.
    • (1996) J. Exp. Med , vol.184 , pp. 747-752
    • Cella, M.1    Scheidegger, D.2    Palmer-Lehmann, K.3    Lane, P.4    Lanzavecchia, A.5    Alber, G.6
  • 10
    • 23944481107 scopus 로고    scopus 로고
    • Unscrambling hepatitis C virus-host interactions
    • Chisari, F. V. 2005. Unscrambling hepatitis C virus-host interactions. Nature 436:930-932.
    • (2005) Nature , vol.436 , pp. 930-932
    • Chisari, F.V.1
  • 11
    • 11844263890 scopus 로고    scopus 로고
    • Enhancement of T helper type 1 immune responses against hepatitis B virus core antigen by PLGA nanopar-ticle vaccine delivery
    • Chong, C. S., M. Cao, W. W. Wong, K. P. Fischer, W. R. Addison, G. S. Kwon, D. L. Tyrrell, and J. Samuel. 2005. Enhancement of T helper type 1 immune responses against hepatitis B virus core antigen by PLGA nanopar-ticle vaccine delivery. J. Control. Release 102:85-99.
    • (2005) J. Control. Release , vol.102 , pp. 85-99
    • Chong, C.S.1    Cao, M.2    Wong, W.W.3    Fischer, K.P.4    Addison, W.R.5    Kwon, G.S.6    Tyrrell, D.L.7    Samuel, J.8
  • 13
    • 0029151623 scopus 로고
    • Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection
    • Diepolder, H. M., R. Zachoval, R. M. Hoffmann, E. A. Wierenga, T. San-tantonio, M. C. Jung, D. Eichenlaub, and G. R. Pape. 1995. Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet 346:1006-1007.
    • (1995) Lancet , vol.346 , pp. 1006-1007
    • Diepolder, H.M.1    Zachoval, R.2    Hoffmann, R.M.3    Wierenga, E.A.4    San-tantonio, T.5    Jung, M.C.6    Eichenlaub, D.7    Pape, G.R.8
  • 14
    • 0037851770 scopus 로고    scopus 로고
    • Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation
    • Dolganiuc, A., K. Kodys, A. Kopasz, C. Marshall, T. Do, L. Romics, Jr., P. Mandrekar, M. Zapp, and G. Szabo. 2003. Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation. J. Immunol. 170:5615-5624.
    • (2003) J. Immunol , vol.170 , pp. 5615-5624
    • Dolganiuc, A.1    Kodys, K.2    Kopasz, A.3    Marshall, C.4    Do, T.5    Romics Jr., L.6    Mandrekar, P.7    Zapp, M.8    Szabo, G.9
  • 15
    • 0032212215 scopus 로고    scopus 로고
    • Genetic immunization generates cellular and humoral immune responses against the non-structural proteins of the hepatitis C virus in a murine model
    • Encke, J., J. zu Putlitz, M. Geissler, and J. R. Wands. 1998. Genetic immunization generates cellular and humoral immune responses against the non-structural proteins of the hepatitis C virus in a murine model. J. Immunol. 161:4917-4923.
    • (1998) J. Immunol , vol.161 , pp. 4917-4923
    • Encke, J.1    zu Putlitz, J.2    Geissler, M.3    Wands, J.R.4
  • 16
    • 11144246891 scopus 로고    scopus 로고
    • Type 1 interferon augments DNA-based vaccination against hepatitis C virus core protein
    • Gehring, S., S. H. Gregory, N. Kuzushita, and J. R. Wands. 2005. Type 1 interferon augments DNA-based vaccination against hepatitis C virus core protein. J. Med. Virol. 75:249-257.
    • (2005) J. Med. Virol , vol.75 , pp. 249-257
    • Gehring, S.1    Gregory, S.H.2    Kuzushita, N.3    Wands, J.R.4
  • 19
  • 23
    • 0034008431 scopus 로고    scopus 로고
    • Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo
    • He, Y., A. A. Pimenov, J. V. Nayak, J. Plowey, L. D. Falo, Jr., and L. Huang. 2000. Intravenous injection of naked DNA encoding secreted flt3 ligand dramatically increases the number of dendritic cells and natural killer cells in vivo. Hum. Gene Ther. 11:547-554.
    • (2000) Hum. Gene Ther , vol.11 , pp. 547-554
    • He, Y.1    Pimenov, A.A.2    Nayak, J.V.3    Plowey, J.4    Falo Jr., L.D.5    Huang, L.6
  • 24
    • 0032418812 scopus 로고    scopus 로고
    • The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses
    • Kalams, S. A., and B. D. Walker. 1998. The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses. J. Exp. Med. 188:2199-2204.
    • (1998) J. Exp. Med , vol.188 , pp. 2199-2204
    • Kalams, S.A.1    Walker, B.D.2
  • 25
    • 0033136306 scopus 로고    scopus 로고
    • Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals
    • Kanto, T., N. Hayashi, T. Takehara, T. Tatsumi, N. Kuzushita, A. Ito, Y. Sasaki, A. Kasahara, and M. Hori. 1999. Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. J. Immunol. 162:5584-5591.
    • (1999) J. Immunol , vol.162 , pp. 5584-5591
    • Kanto, T.1    Hayashi, N.2    Takehara, T.3    Tatsumi, T.4    Kuzushita, N.5    Ito, A.6    Sasaki, Y.7    Kasahara, A.8    Hori, M.9
  • 27
    • 32044443616 scopus 로고    scopus 로고
    • Vaccination with protein-transduced dendritic cells elicits a sustained response to hepatitis C viral antigens
    • Kuzushita, N., S. H. Gregory, N. A. Monti, R. Carlson, S. Gehring, and J. R. Wands. 2006. Vaccination with protein-transduced dendritic cells elicits a sustained response to hepatitis C viral antigens. Gastroenterology 130:453-464.
    • (2006) Gastroenterology , vol.130 , pp. 453-464
    • Kuzushita, N.1    Gregory, S.H.2    Monti, N.A.3    Carlson, R.4    Gehring, S.5    Wands, J.R.6
  • 28
    • 0037299113 scopus 로고    scopus 로고
    • Current therapy for hepatitis C: Pegylated interferon and ribavirin
    • McHutchison, J. G., and M. W. Fried. 2003. Current therapy for hepatitis C: pegylated interferon and ribavirin. Clin. Liver Dis. 7:149-161.
    • (2003) Clin. Liver Dis , vol.7 , pp. 149-161
    • McHutchison, J.G.1    Fried, M.W.2
  • 31
    • 33748795860 scopus 로고    scopus 로고
    • Microparticle-based technologies for vaccines
    • O'Hagan, D. T., M. Singh, and J. B. Ulmer. 2006. Microparticle-based technologies for vaccines. Methods 40:10-19.
    • (2006) Methods , vol.40 , pp. 10-19
    • O'Hagan, D.T.1    Singh, M.2    Ulmer, J.B.3
  • 32
    • 0036152383 scopus 로고    scopus 로고
    • Co-delivery of GM-CSF gene enhances the immune responses of hepatitis C viral core protein-expressing DNA vaccine: Role of dendritic cells
    • Ou-Yang, P., L. H. Hwang, M. H. Tao, B. L. Chiang, and D. S. Chen. 2002. Co-delivery of GM-CSF gene enhances the immune responses of hepatitis C viral core protein-expressing DNA vaccine: role of dendritic cells. J. Med. Virol. 66:320-328.
    • (2002) J. Med. Virol , vol.66 , pp. 320-328
    • Ou-Yang, P.1    Hwang, L.H.2    Tao, M.H.3    Chiang, B.L.4    Chen, D.S.5
  • 33
    • 4444243196 scopus 로고    scopus 로고
    • Hepatitis C treatment update
    • Pearlman, B. L. 2004. Hepatitis C treatment update. Am. J. Med. 117:344-352.
    • (2004) Am. J. Med , vol.117 , pp. 344-352
    • Pearlman, B.L.1
  • 34
    • 2442672794 scopus 로고    scopus 로고
    • Hepatitis C virus persistence after spontaneous or treatment-induced resolution of hepatitis C
    • Pham, T. N., S. A. MacParland, P. M. Mulrooney, H. Cooksley, N. V. Naoumov, and T. I. Michalak. 2004. Hepatitis C virus persistence after spontaneous or treatment-induced resolution of hepatitis C. J. Virol. 78:5867-5874.
    • (2004) J. Virol , vol.78 , pp. 5867-5874
    • Pham, T.N.1    MacParland, S.A.2    Mulrooney, P.M.3    Cooksley, H.4    Naoumov, N.V.5    Michalak, T.I.6
  • 35
    • 0035340499 scopus 로고    scopus 로고
    • Cutting edge: Intravenous soluble antigen is presented to CD4 T cells by CD8- dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells
    • Pooley, J. L., W. R. Heath, and K. Shortman. 2001. Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8- dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells. J. Immunol. 166:5327-5330.
    • (2001) J. Immunol , vol.166 , pp. 5327-5330
    • Pooley, J.L.1    Heath, W.R.2    Shortman, K.3
  • 36
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann, B., and M. Nascimbeni. 2005. Immunology of hepatitis B virus and hepatitis C virus infection. Nat. Rev. Immunol. 5:215-229.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 38
    • 0141566336 scopus 로고    scopus 로고
    • Hepatitis C virus structural proteins impair dendritic cell maturation and inhibit in vivo induction of cellular immune responses
    • Sarobe, P., J. J. Lasarte, A. Zabaleta, L. Arribillaga, A. Arina, I. Melero, F. Borras-Cuesta, and J. Prieto. 2003. Hepatitis C virus structural proteins impair dendritic cell maturation and inhibit in vivo induction of cellular immune responses. J. Virol. 77:10862-10871.
    • (2003) J. Virol , vol.77 , pp. 10862-10871
    • Sarobe, P.1    Lasarte, J.J.2    Zabaleta, A.3    Arribillaga, L.4    Arina, A.5    Melero, I.6    Borras-Cuesta, F.7    Prieto, J.8
  • 39
    • 9244255343 scopus 로고    scopus 로고
    • Cell-mediated immunity and the outcome of hepatitis C virus infection
    • Shoukry, N. H., A. G. Cawthon, and C. M. Walker. 2004. Cell-mediated immunity and the outcome of hepatitis C virus infection. Annu. Rev. Mi-crobiol. 58:391-424.
    • (2004) Annu. Rev. Mi-crobiol , vol.58 , pp. 391-424
    • Shoukry, N.H.1    Cawthon, A.G.2    Walker, C.M.3
  • 41
    • 33846405268 scopus 로고    scopus 로고
    • Incorporation of CpG oligonucleotide ligand into protein-loaded particle vaccines promotes antigen-specific CD8 T-cell immunity
    • Standley, S. M., I. Mende, S. L. Goh, Y. J. Kwon, T. T. Beaudette, E. G. Engleman, and J. M. Frechet. 2007. Incorporation of CpG oligonucleotide ligand into protein-loaded particle vaccines promotes antigen-specific CD8 T-cell immunity. Bioconjug. Chem. 18:77-83.
    • (2007) Bioconjug. Chem , vol.18 , pp. 77-83
    • Standley, S.M.1    Mende, I.2    Goh, S.L.3    Kwon, Y.J.4    Beaudette, T.T.5    Engleman, E.G.6    Frechet, J.M.7
  • 42
    • 1842479859 scopus 로고    scopus 로고
    • Diagnosis, management, and treatment of hepatitis C
    • Strader, D. B., T. Wright, D. L. Thomas, and L. B. Seeff. 2004. Diagnosis, management, and treatment of hepatitis C. Hepatology 39:1147-1171.
    • (2004) Hepatology , vol.39 , pp. 1147-1171
    • Strader, D.B.1    Wright, T.2    Thomas, D.L.3    Seeff, L.B.4
  • 43
    • 34748886192 scopus 로고    scopus 로고
    • Dendritic-cell immunotherapy: From ex vivo loading to in vivo targeting
    • Tacken, P. J., I. J. de Vries, R. Torensma, and C. G. Figdor. 2007. Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat. Rev. Immunol. 7:790-802.
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 790-802
    • Tacken, P.J.1    de Vries, I.J.2    Torensma, R.3    Figdor, C.G.4
  • 44
    • 0034030136 scopus 로고    scopus 로고
    • Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C
    • Takaki, A., M. Wiese, G. Maertens, E. Depla, U. Seifert, A. Liebetrau, J. L. Miller, M. P. Manns, and B. Rehermann. 2000. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C. Nat. Med. 6:578-582.
    • (2000) Nat. Med , vol.6 , pp. 578-582
    • Takaki, A.1    Wiese, M.2    Maertens, G.3    Depla, E.4    Seifert, U.5    Liebetrau, A.6    Miller, J.L.7    Manns, M.P.8    Rehermann, B.9
  • 45
    • 0035947270 scopus 로고    scopus 로고
    • How hepatitis C virus counteracts the interferon response: The jury is still out on NS5A
    • Tan, S. L., and M. G. Katze. 2001. How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A. Virology 284:1-12.
    • (2001) Virology , vol.284 , pp. 1-12
    • Tan, S.L.1    Katze, M.G.2
  • 47
    • 0035914925 scopus 로고    scopus 로고
    • Determinants of viral clearance and persistence during acute hepatitis C virus infection
    • Thimme, R., D. Oldach, K. M. Chang, C. Steiger, S. C. Ray, and F. V. Chisari. 2001. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J. Exp. Med. 194:1395-1406.
    • (2001) J. Exp. Med , vol.194 , pp. 1395-1406
    • Thimme, R.1    Oldach, D.2    Chang, K.M.3    Steiger, C.4    Ray, S.C.5    Chisari, F.V.6
  • 48
    • 0031026553 scopus 로고    scopus 로고
    • Detection of type 2-like T-helper cells in hepatitis C virus infection: Implications for hepatitis C virus chronicity
    • Tsai, S. L., Y. F. Liaw, M. H. Chen, C. Y. Huang, and G. C. Kuo. 1997. Detection of type 2-like T-helper cells in hepatitis C virus infection: implications for hepatitis C virus chronicity. Hepatology 25:449-458.
    • (1997) Hepatology , vol.25 , pp. 449-458
    • Tsai, S.L.1    Liaw, Y.F.2    Chen, M.H.3    Huang, C.Y.4    Kuo, G.C.5
  • 50
    • 3042523520 scopus 로고    scopus 로고
    • Targeting dendritic cells with antigen-containing liposomes: A highly effective procedure for induction of antitumor immunity and for tumor immunotherapy
    • van Broekhoven, C. L., C. R. Parish, C. Demangel, W. J. Britton, and J. G. Altin. 2004. Targeting dendritic cells with antigen-containing liposomes: a highly effective procedure for induction of antitumor immunity and for tumor immunotherapy. Cancer Res. 64:4357-4365.
    • (2004) Cancer Res , vol.64 , pp. 4357-4365
    • van Broekhoven, C.L.1    Parish, C.R.2    Demangel, C.3    Britton, W.J.4    Altin, J.G.5
  • 51
    • 33745945647 scopus 로고    scopus 로고
    • Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo
    • Warger, T., P. Osterloh, G. Rechtsteiner, M. Fassbender, V. Heib, B. Schmid, E. Schmitt, H. Schild, and M. P. Radsak. 2006. Synergistic activation of dendritic cells by combined Toll-like receptor ligation induces superior CTL responses in vivo. Blood 108:544-550.
    • (2006) Blood , vol.108 , pp. 544-550
    • Warger, T.1    Osterloh, P.2    Rechtsteiner, G.3    Fassbender, M.4    Heib, V.5    Schmid, B.6    Schmitt, E.7    Schild, H.8    Radsak, M.P.9
  • 52
    • 0037369712 scopus 로고    scopus 로고
    • Novel CD4+ and CD8+ T-cell determinants within the NS3 protein in subjects with spontaneously resolved HCV infection
    • Wertheimer, A. M., C. Miner, D. M. Lewinsohn, A. W. Sasaki, E. Kaufman, and H. R. Rosen. 2003. Novel CD4+ and CD8+ T-cell determinants within the NS3 protein in subjects with spontaneously resolved HCV infection. Hepatology 37:577-589.
    • (2003) Hepatology , vol.37 , pp. 577-589
    • Wertheimer, A.M.1    Miner, C.2    Lewinsohn, D.M.3    Sasaki, A.W.4    Kaufman, E.5    Rosen, H.R.6


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