Hepatitis C virus persistence after spontaneous or treatment-induced resolution of hepatitis C

Journal of Virology

Volumn 78, Issue 11, 2004, Pages 5867-5874

  Pham, Tram N Q ^a   MacParland, Sonya A ^a   Mulrooney, Patricia M ^a   Cooksley, Helen ^b   Naoumov, Nikolai V ^b   Michalak, Tomasz I ^a,c  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGENIC AGENT; VIRUS RNA;

5' UNTRANSLATED REGION; ADULT; ARTICLE; CLINICAL ARTICLE; CONVALESCENCE; DENDRITIC CELL; ERADICATION THERAPY; FEMALE; GENE EXPRESSION; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER FUNCTION TEST; LYMPHOID CELL; MALE; MONONUCLEAR CELL; NUCLEIC ACID HYBRIDIZATION; PERIPHERAL LYMPHOCYTE; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; VIRUS CULTURE; VIRUS GENOME; VIRUS REPLICATION;

ADULT; BASE SEQUENCE; DENDRITIC CELLS; FEMALE; HEPACIVIRUS; HEPATITIS C; HUMANS; INTERLEUKIN-2; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PHYTOHEMAGGLUTININS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL;

EID: 2442672794     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.11.5867-5874.2004     Document Type: Article

References (37)

1. Auffermann-Gretzinger, S., E. B. Keeffe, and S. Levy. 2001. Impaired dendritic cell maturation in patients with chronic, but not resolved, hepatitis C virus infection. Blood 97:3171-3176.
2. Bain, C., A. Fatmi, F. Zoulim, J. P. Zarski, C. Trepo, and G. Inchauspe. 2001. Impaired allostimulatory function of dendritic cells in chronic hepatitis infection. Gastroenterology 120:512-524.
3. Coffin, C. S., and T. I. Michalak. 1999. Persistence of infectious hepadnavirus in offspring of woodchuck mothers recovered from viral hepatitis. J. Clin. Investig. 104:203-212.
4. Cohen, J. 1999. The scientific challenge of hepatitis C virus. Science 285:26-30.
5. Cramp, M. E., P. Carucci, S. Rossol, S. Chokshi, G. Maertens, R. Williams, and N. V. Naoumov. 1999. Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients without hepatitis C viraemia. Gut 44:424-429.
6. El-Serag, H. B., H. Hampel, C. Yeh, and L. Rabeneck. 2002. Extrahepatic manifestation of hepatitis C among United States male veterans. Hepatology 36:1439-1445.
7. Goutagny, N., A. Fatmi, V. De Ledinghen, F. Penin, P. Couzigou, G. Inchauspe, and C. Bain. 2003. Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection. J. Infect. Dis. 187:1951-1958.
8. + T cells. J. Exp. Med. 186:801-812.
9. Hoofnagle, H. J. 2002. Course and outcome of hepatitis C. Hepatology 36:S21-S29.
10. Kato, N., M. Hijikata, Y. Ootsuyama, M. Nakagawa, S. Ohkoshi, T. Sugimura, and K. Shimotohno. 1990. Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis. Proc. Natl. Acad. Sci. USA 87:9524-9528.
11. Kato, N., T. Nakazawa, T. Mizutani, and K. Shimotohno. 1995. Susceptibility of human T lymphotropic virus type 1 infected cell line MT-2 to hepatitis C virus infection. Biochem. Biophys. Res. Commun. 206:863-869.
12. Kay, J. E. 1991. Mechanisms of T lymphocyte activation. Immunol. Lett. 29:51-54.
13. Korba, B. E., P. J. Cote, and J. L. Gerin. 1988. Mitogen-induced replication of woodchuck hepatitis virus in cultured peripheral blood lymphocytes. Science 241:1213-1216.
14. Koziel, M. J., D. K. Wong, D. Dudley, M. Houghton, and B. D. Walker. 1997. Hepatitis C virus-specific cytolytic T lymphocyte and T helper cell response in seronegative persons. J. Infect. Dis. 176:859-866.
15. Lanford, R. E., and D. Chavez. 1998. Strand-specific rTth RT-PCR for the analysis of HCV replication, p. 471-481. In J. Y.-N. Lau (ed.), Hepatitis C protocols. Humana Press, Totowa, N. J.
16. + T cells. J. Immunol. 165:1182-1190.
17. Lerat, H., F. Berby, M. A. Traubaud, O. Vidalin, M. Major, C. Trepo, and G. Inchauspe. 1996. Specific detection of hepatitis C virus strand RNA in hematopoietic cells. J. Clin. Investig. 97:845-851.
18. Lew, Y.-Y., and T. I. Michalak. 2001. In vitro and in vivo infectivity and pathogenicity of the lymphoid cell-derived woodchuck hepatitis virus. J. Virol. 75:1770-1782.
19. Michalak, T. I., C. Pasquinelli, S. Guilhot, and F. V. Chisari. 1994. Hepatitis B virus persistence after recovery from acute viral hepatitis. J. Clin. Investig. 93:230-239.
20. Michalak, T. I., I. U. Pardoe, C. S. Coffin, N. D. Churchill, D. S. Freake, P. Smith, and C. L. Trelegan. 1999. Occult lifelong persistence of infectious hepadnavirus and residual liver inflammation in woodchucks convalescent from acute viral hepatitis. Hepatology 29:928-938.
21. Michalak, T. I. 2000. Occult persistence and lymphotropism of hepadnaviral infection: insights from the woodchuck viral hepatitis model. Immunol. Rev. 174:98-111.
22. Michalak, T. I., P. M. Mulrooney, and C. S. Coffin. 2004. Low doses of hepadnavirus induce infection of the lymphatic system that does not engage the liver. J. Virol. 78:1730-1738.
23. +). Blood 94:1138-1139.
24. Musto, P. 2002. Hepatitis C virus infection and B cell non-Hodgkin's lymphomas: more than a simple association. Clin. Lymphoma 3:150-160.
25. Nissen, E., M. Hohne, and H. Schreier. 1994. In vitro replication of hepatitis C virus in a human lymphoid cell line (H9). J. Hepatol. 20:437-442.
26. Okuda, M., K. Hino, M. Korenaga, Y. Yamaguchi, Y. Katoh, and K. Okita. 1999. Differences in hypervariable region 1 quasispecies of hepatitis C virus in human serum, peripheral blood mononuclear cells, and liver. Hepatology 29:217-222.
27. Oldstone, M. B. 1996. Virus-lymphoid cell interactions. Proc. Natl. Acad. Sci. USA 93:12756-12758.
28. Radkowski, M., J. Wilkinson, M. Nowicki, D. Adair, H. Varga, C. Ingui, J. Rakela, and T. Laskus. 2002. Search for Hepatitis C virus negative-strand RNA sequences and analysis of viral sequences in the central nervous system: evidence of replication. J. Virol. 76:600-608.
29. Radowski, M., J. Kubicka, E. Kisiel, A. Cianciara, M. Nowicki, J. Rakela, and T. Laskus. 2000. Detection of active hepatitis C virus and hepatitis G virus/GB virus C replication in bone marrow in human subjects. Blood 95:3986-3990.
30. Rehermann, B., C. Ferrari, C. Pasquinelli, and F. V. Chisari. 1996. The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of cytotoxic T-lymphocyte response. Nat. Med. 2:1104-1108.
31. Rodriguez-Inigo, E., M. Casqueiro, S. Navas, J. Bartolome, M. Pardo, and V. Carreno. 2000. Fluorescent "in situ" hybridization of hepatitis C virus RNA in peripheral blood mononuclear cells from patients with chronic hepatitis C. J. Med. Virol. 60:269-274.
32. Romani, N., S. Grunner, D. Brang, E. Kampen, A. Lenz, B. Trockenbacher, G. Konwalinka, P. O. Fritsch, R. M. Steinman, and G. Schuler. 1994. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180:83-93.
33. Shimizu, Y. K., A. Iwamoto, M. Hijikata, R. H. Purcell, and H. Yoshikura. 1992. Evidence for in vitro replication of hepatitis C virus genome in a human T cell line. Proc. Natl. Acad. Sci. USA 89:5477-5481.
34. Shimizu, Y. K., H. Igarashi, T. Kiyohara, M. Shapiro, D. C. Wong, R. H. Purcell, and H. Yoshikura. 1998. Infection of a chimpanzee with hepatitis C virus grown in cell culture. J. Gen. Virol. 79:1383-1386.
35. Sung, V. M. H., S. Shimodaira, A. L. Doughty, G. R. Picchio, H. Can, B. T. S. Yen, K. L. Lindsay, A. M. Levine, and M. M. C. Lai. 2003. Establishment of B cell lymphoma cell lines persistently infected with hepatitis C virus in vivo and in vitro: the apoptotic effects of virus infection. J. Virol. 77:2134-2146.
36. Takaki, A., M. Wiese, G. Maertens, E. Depla, U. Seifert, A. Liebetrau, J. L. Miller, M. P. Manns, and B. Rehermann. 2000. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single source outbreak of hepatitis C. Nat. Med. 6:578-582.
37. Willems, M., K. Peerlinck, H. Moshage, I. Deleu, C. Van den Eynde, J. Vermylen, and S. H. Yap. 1994. Hepatitis C virus RNAs in plasma and in peripheral blood mononuclear cells of hemophiliacs with chronic hepatitis C: evidence for viral replication in peripheral blood mononuclear cells. J. Med. Virol. 42:272-278.