Synthesis and biological evaluation of a 5-6-5 imidazole-phenyl-thiazole based α-helix mimetic

Organic Letters

Volumn 11, Issue 1, 2009, Pages 25-28

  Cummings, Christopher G ^a   Ross, Nathan T ^a   Katt, William P ^a   Hamilton, Andrew D ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETIC MATERIAL; IMIDAZOLE DERIVATIVE; PROTEIN CDC42; THIAZOLE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; MOLECULAR MIMICRY; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

BIOMIMETIC MATERIALS; CDC42 GTP-BINDING PROTEIN; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; IMIDAZOLES; MODELS, MOLECULAR; MOLECULAR MIMICRY; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 59649121289     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol8022962     Document Type: Article

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