Recruitment of HDAC4 by transcription factor YY1 represses HOXB13 to affect cell growth in AR-negative prostate cancers

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 5, 2009, Pages 1094-1101

  Ren, Guoling ^a   Zhang, Guocui ^a   Dong, Zhixiong ^a   Liu, Zhiwei ^a   Li, Lin ^a   Feng, Yunpeng ^a   Su, Dongmei ^a   Zhang, Yu ^a   Huang, Baiqu ^a   Lu, Jun ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

Cell growth; HDAC4; HOXB13; Prostate cancer; YY1

Indexed keywords

BUTYRIC ACID; HISTONE DEACETYLASE 4; HOMEODOMAIN PROTEIN; HOMEODOMAIN PROTEIN HOXB13; TRANSCRIPTION FACTOR YY1; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL GROWTH; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EPIGENETICS; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; PROMOTER REGION; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ACETYLATION; BINDING SITES; BUTYRATES; CELL DIVISION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; HISTONE DEACETYLASES; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; MALE; PROMOTER REGIONS, GENETIC; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC; TRANSFECTION; YY1 TRANSCRIPTION FACTOR;

EID: 59649121111     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.10.015     Document Type: Article

References (40)

1. Aalfs J.D., and Kingston R.E. What does 'chromatin remodeling' mean?. Trends Biochem Sci 25 (2000) 548-555
2. Affar el B., Gay F., Shi Y., Liu H., Huarte M., Wu S., et al. Essential dosage-dependent functions of the transcription factor yin yang 1 in late embryonic development and cell cycle progression. Mol Cell Biol 26 (2006) 3565-3581
3. Atchison L., Ghias A., Wilkinson F., Bonini N., and Atchison M.L. Transcription factor YY1 functions as a PcG protein in vivo. EMBO J 22 (2003) 1347-1358
4. Baradari V., Huether A., Hopfner M., Schuppan D., and Scherubl H. Antiproliferative and proapoptotic effects of histone deacetylase inhibitors on gastrointestinal neuroendocrine tumor cells. Endocr Relat Cancer 13 (2006) 1237-1250
5. Beuchle D., Struhl G., and Muller J. Polycomb group proteins and heritable silencing of Drosophila Hox genes. Development 128 (2001) 993-1004
6. Brachmann C.B., Sherman J.M., Devine S.E., Cameron E.E., Pillus L., and Boeke J.D. The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability. Genes Dev 9 (1995) 2888-2902
7. Brownell J.E., and Allis C.D. Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr Opin Genet Dev 6 (1996) 176-184
8. Buggy J.J., Sideris M.L., Mak P., Lorimer D.D., McIntosh B., and Clark J.M. Cloning and characterization of a novel human histone deacetylase, HDAC8. Biochem J 350 Pt 1 (2000) 199-205
9. Cross D.S., and Burmester J.K. Functional characterization of the HOXB13 promoter region. Med Oncol (2007)
10. Economides K.D., and Capecchi M.R. Hoxb13 is required for normal differentiation and secretory function of the ventral prostate. Development 130 (2003) 2061-2069
11. Frye R.A. Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 273 (2000) 793-798
12. Gordon S., Akopyan G., Garban H., and Bonavida B. Transcription factor YY1: structure, function, and therapeutic implications in cancer biology. Oncogene 25 (2006) 1125-1142
13. Grozinger C.M., and Schreiber S.L. Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. Chem Biol 9 (2002) 3-16
14. Han S., Lu J., Zhang Y., Cheng C., Han L., Wang X., et al. Recruitment of histone deacetylase 4 by transcription factors represses interleukin-5 transcription. Biochem J 400 (2006) 439-448
15. Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., and Pease L.R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77 (1989) 51-59
16. Hoffmann M.J., Engers R., Florl A.R., Otte A.P., Muller M., and Schulz W.A. Expression changes in EZH2, but not in BMI-1, SIRT1, DNMT1 or DNMT3B are associated with DNA methylation changes in prostate cancer. Cancer Biol Ther 6 (2007) 1403-1412
17. Huang L., Pu Y., Hepps D., Danielpour D., and Prins G.S. Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes. Endocrinology 148 (2007) 1235-1245
18. Imai S., Armstrong C.M., Kaeberlein M., and Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403 (2000) 795-800
19. Jung C., Kim R.S., Lee S.J., Wang C., and Jeng M.H. HOXB13 homeodomain protein suppresses the growth of prostate cancer cells by the negative regulation of T-cell factor 4. Cancer Res 64 (2004) 3046-3051
20. Jung C., Kim R.S., Zhang H.J., Lee S.J., and Jeng M.H. HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signaling. Cancer Res 64 (2004) 9185-9192
21. Jung C., Kim R.S., Zhang H., Lee S.J., Sheng H., Loehrer P.J., et al. HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation. Br J Cancer 92 (2005) 2233-2239
22. Kelly W.K., O'Connor O.A., and Marks P.A. Histone deacetylase inhibitors: from target to clinical trials. Expert Opin Investig Drugs 11 (2002) 1695-1713
23. Krupitza G., Grill S., Harant H., Hulla W., Szekeres T., Huber H., et al. Genes related to growth and invasiveness are repressed by sodium butyrate in ovarian carcinoma cells. Br J Cancer 73 (1996) 433-438
24. Kuzmichev A., Margueron R., Vaquero A., Preissner T.S., Scher M., Kirmizis A., et al. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proc Natl Acad Sci USA 102 (2005) 1859-1864
25. Lewis M.T. Homeobox genes in mammary gland development and neoplasia. Breast Cancer Res 2 (2000) 158-169
26. Lomonte P., Thomas J., Texier P., Caron C., Khochbin S., and Epstein A.L. Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1. J Virol 78 (2004) 6744-6757
27. Lu J., Sun H., Wang X., Liu C., Xu X., Li F., et al. Interleukin-12 p40 promoter activity is regulated by the reversible acetylation mediated by HDAC1 and p300. Cytokine 31 (2005) 46-51
28. Miao J., Wang Z., Provencher H., Muir B., Dahiya S., Carney E., et al. HOXB13 promotes ovarian cancer progression. Proc Natl Acad Sci USA 104 (2007) 17093-17098
29. Okuda H., Toyota M., Ishida W., Furihata M., Tsuchiya M., Kamada M., et al. Epigenetic inactivation of the candidate tumor suppressor gene HOXB13 in human renal cell carcinoma. Oncogene 25 (2006) 1733-1742
30. Seligson D., Horvath S., Huerta-Yepez S., Hanna S., Garban H., Roberts A., et al. Expression of transcription factor Yin Yang 1 in prostate cancer. Int J Oncol 27 (2005) 131-141
31. Shi Y., Lee J.S., and Galvin K.M. Everything you have ever wanted to know about Yin Yang 1. Biochim Biophys Acta 1332 (1997) F49-66
32. Shrivastava A., and Calame K. An analysis of genes regulated by the multi-functional transcriptional regulator Yin Yang-1. Nucleic Acids Res 22 (1994) 5151-5155
33. Sterner D.E., and Berger S.L. Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 64 (2000) 435-459
34. Sui G., Affar el B., Shi Y., Brignone C., Wall N.R., Yin P., et al. Yin Yang 1 is a negative regulator of p53. Cell 117 (2004) 859-872
35. Taunton J., Hassig C.A., and Schreiber S.L. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science 272 (1996) 408-411
36. Terao Y., Nishida J., Horiuchi S., Rong F., Ueoka Y., Matsuda T., et al. Sodium butyrate induces growth arrest and senescence-like phenotypes in gynecologic cancer cells. Int J Cancer 94 (2001) 257-267
37. Thomas M.J., and Seto E. Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key?. Gene 236 (1999) 197-208
38. Verdel A., and Khochbin S. Identification of a new family of higher eukaryotic histone deacetylases. Coordinate expression of differentiation-dependent chromatin modifiers. J Biol Chem 274 (1999) 2440-2445
39. Wang X., Feng Y., Xu L., Chen Y., Zhang Y., Su D., et al. YY1 restrained cell senescence through repressing the transcription of p16. Biochim Biophys Acta (2008)
40. Zhao X., Ito A., Kane C.D., Liao T.S., Bolger T.A., Lemrow S.M., et al. The modular nature of histone deacetylase HDAC4 confers phosphorylation-dependent intracellular trafficking. J Biol Chem 276 (2001) 35042-35048