Selective blockade of CaMKII-α inhibits NMDA-induced caspase-3-dependent cell death but does not arrest PARP-1 activation or loss of plasma membrane selectivity in rat retinal neurons

Brain Research

Volumn 1256, Issue , 2009, Pages 190-204

  Goebel, Dennis J ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Calcium calmodulin dependent kinase II blockade; Caspase 3 activation; Ethidium bromide staining; PARP activity; TUNEL labeling

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II ALPHA; CASPASE 3; N METHYL DEXTRO ASPARTIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL LOSS; CELL MEMBRANE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MALE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA DISEASE; RETINA GANGLION CELL; RETINA NERVE CELL;

ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CASPASE 3; CELL DEATH; CELL MEMBRANE; CELL SURVIVAL; ENZYME ACTIVATION; MALE; N-METHYLASPARTATE; NECROSIS; PEPTIDES; PHENANTHRENES; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; RETINAL NEURONS; SIGNAL TRANSDUCTION;

RATTUS;

EID: 59649120850     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.12.051     Document Type: Article

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