Homeobox gene CDX2 inhibits human pancreatic cancer cell proliferation by down-regulating cyclin D1 transcriptional activity

Pancreas

Volumn 38, Issue 1, 2009, Pages 49-57

  Takahashi, Kenji ^a   Hirano, Fuminori ^a   Matsumoto, Kakuya ^a   Aso, Kazunobu ^a   Haneda, Masakazu ^a  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

CDX2; Cell proliferation; Cyclin D1; NF JB; Pancreatic cancer; Transcriptional activity

Indexed keywords

BETA ACTIN; CYCLIN D1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MESSENGER RNA; TRANSCRIPTION FACTOR CDX1; TRANSCRIPTION FACTOR RELA; CCND1 PROTEIN, HUMAN; CDX1 PROTEIN, HUMAN; CDX2 PROTEIN, HUMAN; CYCLOOXYGENASE 2; HOMEODOMAIN PROTEIN; PTGS2 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CANCER CELL CULTURE; CDX2 GENE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE INDUCTION; GENE REPRESSION; GENETIC TRANSFECTION; HOMEOBOX; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; ADENOSQUAMOUS CARCINOMA; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PANCREAS CARCINOMA; PANCREAS ISLET CELL CARCINOMA; PANCREAS TUMOR; PATHOLOGY; PROMOTER REGION; TIME; TUMOR CELL LINE;

CARCINOMA, ADENOSQUAMOUS; CARCINOMA, ISLET CELL; CARCINOMA, PANCREATIC DUCTAL; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; CYCLOOXYGENASE 2; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; NF-KAPPA B; PANCREATIC NEOPLASMS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 59649111596     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e31817fa2ba     Document Type: Article

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