Identifi cation of channel-lining amino acid residue in the hydrophobic segment of colicin ia

Journal of General Physiology

Volumn 132, Issue 6, 2008, Pages 693-707

  Kienker, Paul K ^a   Jakes, Karen S ^a   Finkelstein, Alan ^a,b  

^a Department of Physiology and Biophysics ^*  (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL PROTEIN; COLICIN 1A; CYSTEINE; GLYCINE; METHANETHIOSULFONATE; REAGENT; THIOL DERIVATIVE; THREONINE; UNCLASSIFIED DRUG; COLICIN; ESCHERICHIA COLI PROTEIN; HELIX LOOP HELIX PROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONFORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG STRUCTURE; HYDROPHOBICITY; ION CONDUCTANCE; LIPID BILAYER; MUTANT; NONHUMAN; PROTEIN DOMAIN; PROTEIN STRUCTURE; TARGET CELL; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CHEMISTRY; GENETICS; ION TRANSPORT; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; COLICINS; ESCHERICHIA COLI PROTEINS; HELIX-LOOP-HELIX MOTIFS; HYDROPHOBICITY; ION CHANNEL GATING; ION TRANSPORT; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 59649092389     PISSN: 00221295     EISSN: 15407748     Source Type: Journal    
DOI: 10.1085/jgp.200810042     Document Type: Article

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