NRP/B mutations impair Nrf2-dependent NQO1 induction in human primary brain tumors

Oncogene

Volumn 28, Issue 3, 2009, Pages 378-389

  Seng, S ^a   Avraham, H K ^a   Birrane, G ^a   Jiang, S ^a   Li, H ^a   Katz, G ^a   Bass, C E ^a   Zagozdzon, R ^a   Avraham, S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

NQO1; Nrf2; NRP B mutation; Primary brain tumors

Indexed keywords

ACTIN BINDING PROTEIN; ECTODERMAL NEURAL CORTEX 1 PROTEIN; ECTODERMAL-NEURAL CORTEX 1 PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; HYDROGEN PEROXIDE; KEAP1 PROTEIN, HUMAN; NEUROPEPTIDE; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; NUCLEAR PROTEIN; OXIDIZING AGENT; PHOSPHOPROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SIGNAL PEPTIDE; TRANSCRIPTION FACTOR NRF2;

ANIMAL; ARTICLE; BRAIN TUMOR; CELL NUCLEUS; CYTOPLASM; ENZYME ACTIVATION; GENETICS; HUMAN; IMMUNOLOGY; IMMUNOPRECIPITATION; METABOLISM; MOUSE; MUTATION; OXIDATIVE STRESS; PATHOLOGY; PROMOTER REGION; PROTEIN TRANSPORT;

ANIMALS; BRAIN NEOPLASMS; CELL NUCLEUS; CYTOPLASM; ENZYME ACTIVATION; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROGEN PEROXIDE; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROFILAMENT PROTEINS; MUTATION; NAD(P)H DEHYDROGENASE (QUINONE); NEUROPEPTIDES; NF-E2-RELATED FACTOR 2; NUCLEAR PROTEINS; OXIDANTS; OXIDATIVE STRESS; PHOSPHOPROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN TRANSPORT;

EID: 59649090050     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.396     Document Type: Article

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