A method for the quantification of biomarkers of exposure to acrylonitrile and 1,3-butadiene in human urine by column-switching liquid chromatography- tandem mass spectrometry

Analytical and Bioanalytical Chemistry

Volumn 393, Issue 3, 2009, Pages 969-981

  Schettgen, T ^a   Musiol, A ^a   Alt, A ^a   Ochsmann, E ^a   Kraus, T ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Biomarkers of exposure; Carcinogen; Mass spectrometry; Passive smoke

Indexed keywords

BIOMARKERS; BODY FLUIDS; BUTADIENE; CARCINOGENS; CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; INDUSTRIAL CHEMICALS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; METHANOL; SMOKE; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS;

ADDITIONAL SAMPLES; ANALYTES; ANALYTICAL COLUMNS; BIOMARKERS OF EXPOSURE; CARCINOGEN; COLUMN-SWITCHING; ENVIRONMENTAL POLLUTANTS; ENVIRONMENTAL STUDIES; GENERAL POPULATIONS; HIGH PRODUCTION VOLUMES; HUMAN URINES; INTERNAL EXPOSURES; INTERNAL STANDARDS; ISOMERIC MIXTURES; LC/MS/MS; LIMITS OF QUANTIFICATIONS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRIES; MATRIXES; MERCAPTURIC ACIDS; OCCUPATIONAL EXPOSURES; ON-LINE EXTRACTIONS; PASSIVE SMOKE; RESTRICTED ACCESS MATERIALS; SENSITIVE METHODS; SIMULTANEOUS DETERMINATIONS; TANDEM MASS SPECTROMETRIES; URINE SAMPLES;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

1,3 BUTADIENE; 1,3 BUTADIENE DERIVATIVE; 1,3-BUTADIENE; ACRYLONITRILE; BIOLOGICAL MARKER;

ARTICLE; CALIBRATION; CHEMICAL STRUCTURE; HUMAN; LIQUID CHROMATOGRAPHY; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; TIME; URINE;

ACRYLONITRILE; BIOLOGICAL MARKERS; BUTADIENES; CALIBRATION; CHROMATOGRAPHY, LIQUID; HUMANS; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 59549094580     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-008-2510-1     Document Type: Article

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