Molecular analysis of the Ink4a/Rb1-Arf/Tp53 pathways in radon-induced rat lung tumors

Lung Cancer

Volumn 63, Issue 3, 2009, Pages 348-353

  Bastide, Kristell ^a   Guilly, Marie Noëlle ^a   Bernaudin, Jean François ^b   Joubert, Christophe ^a   Lectard, Bruno ^a   Levalois, Céline ^a   Malfoy, Bernard ^b,c,d   Chevillard, Sylvie ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c INSTITUT CURIE   (France)

^d CNRS   (France)

Author keywords

Arf; Ink4a; Lung cancer; Radon; Rat; Rb1; Tp53 mutation

Indexed keywords

ARF PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; MESSENGER RNA; PROTEIN MDM2; PROTEIN MDMX; PROTEIN P53; RADON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; GENE DELETION; GENE LOCUS; GENE MUTATION; GENETIC CORRELATION; HETEROZYGOSITY LOSS; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; LUNG CARCINOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN METHYLATION; RADIATION CARCINOGENESIS; RAT; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOGENS, ENVIRONMENTAL; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MUTATION; NEOPLASMS, EXPERIMENTAL; POLYMERASE CHAIN REACTION; RADON; RATS; RATS, INBRED F344; RATS, INBRED WF; RATS, SPRAGUE-DAWLEY; RETINOBLASTOMA PROTEIN; RNA, NEOPLASM; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53;

EID: 59449107568     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2008.06.007     Document Type: Article

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