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Volumn 29, Issue 2, 2009, Pages 217-224

Edothelial nitric oxide synthase inhibits G 12/13 and Rho-Kinase activated by the angiotensin II type-1 receptor implication in vascular migration

Author keywords

Angiotensin II; G protein; Nitric oxide synthase; Vascular smooth muscle

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN 12; G PROTEIN 13; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GUANINE NUCLEOTIDE BINDING PROTEIN; NITRIC OXIDE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PHOSPHOPROTEIN PHOSPHATASE 1; PPP1R12A PROTEIN, RAT;

EID: 59449099174     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.181024     Document Type: Article
Times cited : (34)

References (57)
  • 1
    • 0033635110 scopus 로고    scopus 로고
    • Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells
    • Touyz RM, Schiffrin EL. Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells. Pharmacol Rev. 2000;52:639-672.
    • (2000) Pharmacol Rev , vol.52 , pp. 639-672
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 2
    • 33846362954 scopus 로고    scopus 로고
    • Angiotensin II cell signaling: Physiological and pathological effects in the cardiovascular system
    • Mehta PK, Griendling KK. Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol. 2007;292:C82-C97.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Mehta, P.K.1    Griendling, K.K.2
  • 3
    • 33644857156 scopus 로고    scopus 로고
    • Angiotensin II regulates vascular and endothelial dysfunction: Recent topics of Angiotensin II type-1 receptor signaling in the vasculature
    • Nakashima H, Suzuki H, Ohtsu H, Chao JY, Utsunomiya H, Frank GD, Eguchi S. Angiotensin II regulates vascular and endothelial dysfunction: recent topics of Angiotensin II type-1 receptor signaling in the vasculature. Curr Vasc Pharmacol. 2006;4:67-78.
    • (2006) Curr Vasc Pharmacol , vol.4 , pp. 67-78
    • Nakashima, H.1    Suzuki, H.2    Ohtsu, H.3    Chao, J.Y.4    Utsunomiya, H.5    Frank, G.D.6    Eguchi, S.7
  • 4
    • 0029111432 scopus 로고
    • Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensinl receptors
    • Dubey RK, Jackson EK, Luscher TF. Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensinl receptors. J Clin Invest. 1995;96:141-149.
    • (1995) J Clin Invest , vol.96 , pp. 141-149
    • Dubey, R.K.1    Jackson, E.K.2    Luscher, T.F.3
  • 5
    • 33750884859 scopus 로고    scopus 로고
    • Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide
    • Ritchie RH, Schiebinger RJ, LaPointe MC, Marsh JD. Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide. Am J Physiol. 1998;275:H1370-H1374.
    • (1998) Am J Physiol , vol.275
    • Ritchie, R.H.1    Schiebinger, R.J.2    LaPointe, M.C.3    Marsh, J.D.4
  • 6
    • 0037234243 scopus 로고    scopus 로고
    • Functional interplay between angiotensin II and nitric oxide: Cyclic GMP as a key mediator
    • Yan C, Kim D, Aizawa T, Berk BC. Functional interplay between angiotensin II and nitric oxide: cyclic GMP as a key mediator. Arterioscler Thromb Vasc Biol. 2003;23:26-36.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 26-36
    • Yan, C.1    Kim, D.2    Aizawa, T.3    Berk, B.C.4
  • 7
    • 0033903230 scopus 로고    scopus 로고
    • Nitric oxide synthase in atherosclerosis and vascular injury: Insights from experimental gene therapy
    • Channon KM, Qian H, George SE. Nitric oxide synthase in atherosclerosis and vascular injury: insights from experimental gene therapy. Arteriosder Thromb Vasc Biol. 2000;20:1873-1881.
    • (2000) Arteriosder Thromb Vasc Biol , vol.20 , pp. 1873-1881
    • Channon, K.M.1    Qian, H.2    George, S.E.3
  • 8
    • 0035810911 scopus 로고    scopus 로고
    • Therapeutic potential of nitric oxide synthase gene manipulation
    • von der Leyen HE, Dzau VJ. Therapeutic potential of nitric oxide synthase gene manipulation. Circulation. 2001;103:2760-2765.
    • (2001) Circulation , vol.103 , pp. 2760-2765
    • von der Leyen, H.E.1    Dzau, V.J.2
  • 12
    • 0032920339 scopus 로고    scopus 로고
    • Central role of the MAPK pathway in ang II-mediated DNA synthesis and migration in rat vascular smooth muscle cells
    • Xi XP, Graf K, Goetze S, Fleck E, Hsueh WA, Law RE. Central role of the MAPK pathway in ang II-mediated DNA synthesis and migration in rat vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 1999;19:73-82.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 73-82
    • Xi, X.P.1    Graf, K.2    Goetze, S.3    Fleck, E.4    Hsueh, W.A.5    Law, R.E.6
  • 13
    • 0036289647 scopus 로고    scopus 로고
    • Metalloprotease inhibitor blocks angiotensin II-induced migration through inhibition of epidermal growth factor receptor transactivation
    • Saito S, Frank GD, Motley ED, Dempsey PJ, Utsunomiya H, Inagami T, Eguchi S. Metalloprotease inhibitor blocks angiotensin II-induced migration through inhibition of epidermal growth factor receptor transactivation. Biochem Biophys Res Commun. 2002;294:1023-1029.
    • (2002) Biochem Biophys Res Commun , vol.294 , pp. 1023-1029
    • Saito, S.1    Frank, G.D.2    Motley, E.D.3    Dempsey, P.J.4    Utsunomiya, H.5    Inagami, T.6    Eguchi, S.7
  • 15
    • 12144289314 scopus 로고    scopus 로고
    • Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cells via extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase activation
    • Kyaw M, Yoshizumi M, Tsuchiya K, Kagami S, Izawa Y, Fujita Y, Ali N, Kanematsu Y, Toida K, Ishimura K, Tamaki T. Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cells via extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase activation. Mol Pharmacol. 2004;65:832-841.
    • (2004) Mol Pharmacol , vol.65 , pp. 832-841
    • Kyaw, M.1    Yoshizumi, M.2    Tsuchiya, K.3    Kagami, S.4    Izawa, Y.5    Fujita, Y.6    Ali, N.7    Kanematsu, Y.8    Toida, K.9    Ishimura, K.10    Tamaki, T.11
  • 19
    • 33750602514 scopus 로고    scopus 로고
    • Angiotensin II signal transduction through small GTP-binding proteins: Mechanism and significance in vascular smooth muscle cells
    • Ohtsu H, Suzuki H, Nakashima H, Dhobale S, Frank GD, Motley ED, Eguchi S. Angiotensin II signal transduction through small GTP-binding proteins: mechanism and significance in vascular smooth muscle cells. Hypertension. 2006;48:534-540.
    • (2006) Hypertension , vol.48 , pp. 534-540
    • Ohtsu, H.1    Suzuki, H.2    Nakashima, H.3    Dhobale, S.4    Frank, G.D.5    Motley, E.D.6    Eguchi, S.7
  • 20
    • 29344452247 scopus 로고    scopus 로고
    • Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II
    • Hunyady L, Catt KJ. Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II. Mol Endocrinol. 2006;20:953-970.
    • (2006) Mol Endocrinol , vol.20 , pp. 953-970
    • Hunyady, L.1    Catt, K.J.2
  • 21
    • 33845693028 scopus 로고    scopus 로고
    • Type 1 angiotensin receptor pharmacology: Signaling beyond G proteins
    • Oro C, Qian H, Thomas WG. Type 1 angiotensin receptor pharmacology: signaling beyond G proteins. Pharmacol Ther. 2007;113:210-226.
    • (2007) Pharmacol Ther , vol.113 , pp. 210-226
    • Oro, C.1    Qian, H.2    Thomas, W.G.3
  • 23
    • 0037020262 scopus 로고    scopus 로고
    • cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions
    • Gudi T, Chen JC, Casteel DE, Seasholtz TM, Boss GR, Pilz RB. cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions. J Biol Chem. 2002;277:37382-37393.
    • (2002) J Biol Chem , vol.277 , pp. 37382-37393
    • Gudi, T.1    Chen, J.C.2    Casteel, D.E.3    Seasholtz, T.M.4    Boss, G.R.5    Pilz, R.B.6
  • 24
    • 0037805583 scopus 로고    scopus 로고
    • Serine phosphorylation negatively regulates RhoA in vivo
    • Ellerbroek SM, Wennerberg K, Burridge K. Serine phosphorylation negatively regulates RhoA in vivo. J Biol Chem. 2003;278:19023-19031.
    • (2003) J Biol Chem , vol.278 , pp. 19023-19031
    • Ellerbroek, S.M.1    Wennerberg, K.2    Burridge, K.3
  • 25
    • 0032484219 scopus 로고    scopus 로고
    • Nitric oxide and N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts
    • Wang D, Yu X, Brecher P. Nitric oxide and N-acetylcysteine inhibit the activation of mitogen-activated protein kinases by angiotensin II in rat cardiac fibroblasts. J Biol Chem. 1998;273:33027-33034.
    • (1998) J Biol Chem , vol.273 , pp. 33027-33034
    • Wang, D.1    Yu, X.2    Brecher, P.3
  • 26
    • 0029891057 scopus 로고    scopus 로고
    • Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensitive tyrosine kinase
    • Eguchi S, Matsumoto T, Motley ED, Utsunomiya H, Inagami T. Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensitive tyrosine kinase. J Biol Chem. 1996;271:14169-14175.
    • (1996) J Biol Chem , vol.271 , pp. 14169-14175
    • Eguchi, S.1    Matsumoto, T.2    Motley, E.D.3    Utsunomiya, H.4    Inagami, T.5
  • 27
    • 0037013179 scopus 로고    scopus 로고
    • Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion
    • Scotland RS, Morales-Ruiz M, Chen Y, Yu J, Rudic RD, Fulton D, Gratton JP, Sessa WC. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circ Res. 2002;90:904-910.
    • (2002) Circ Res , vol.90 , pp. 904-910
    • Scotland, R.S.1    Morales-Ruiz, M.2    Chen, Y.3    Yu, J.4    Rudic, R.D.5    Fulton, D.6    Gratton, J.P.7    Sessa, W.C.8
  • 28
    • 33748938039 scopus 로고    scopus 로고
    • The regulator of G protein signaling domain of axin selectively interacts with Galphall but not Galpha13
    • Stemmle LN, Fields TA, Casey PJ. The regulator of G protein signaling domain of axin selectively interacts with Galphall but not Galpha13. Mol Pharmacol. 2006;70:1461-1468.
    • (2006) Mol Pharmacol , vol.70 , pp. 1461-1468
    • Stemmle, L.N.1    Fields, T.A.2    Casey, P.J.3
  • 29
    • 0033601182 scopus 로고    scopus 로고
    • Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt
    • Eguchi S, Iwasaki H, Ueno H, Frank GD, Motley ED, Eguchi K, Marumo F, Hirata Y, Inagami T. Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt. J Biol Chem. 1999;274:36843-36851.
    • (1999) J Biol Chem , vol.274 , pp. 36843-36851
    • Eguchi, S.1    Iwasaki, H.2    Ueno, H.3    Frank, G.D.4    Motley, E.D.5    Eguchi, K.6    Marumo, F.7    Hirata, Y.8    Inagami, T.9
  • 30
    • 0036846134 scopus 로고    scopus 로고
    • Urotensin-II regulates intracellular calcium in dissociated rat spinal cord neurons
    • Filipeanu CM, Brailoiu E, Le Dun S, Dun NJ. Urotensin-II regulates intracellular calcium in dissociated rat spinal cord neurons. J Neurochem. 2002;83:879-884.
    • (2002) J Neurochem , vol.83 , pp. 879-884
    • Filipeanu, C.M.1    Brailoiu, E.2    Le Dun, S.3    Dun, N.J.4
  • 32
    • 0037031156 scopus 로고    scopus 로고
    • Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity
    • Yamaguchi Y, Katoh H, Mori K, Negishi M. Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity. Curr Biol. 2002;12:1353-1358.
    • (2002) Curr Biol , vol.12 , pp. 1353-1358
    • Yamaguchi, Y.1    Katoh, H.2    Mori, K.3    Negishi, M.4
  • 33
    • 22744444166 scopus 로고    scopus 로고
    • Mitogenic signaling by lysophosphatidic acid (LPA) involves Galphal2
    • Radhika V, Hee Ha J, Jayaraman M, Tsim ST, Dhanasekaran N. Mitogenic signaling by lysophosphatidic acid (LPA) involves Galphal2. Oncogene. 2005;24:4597-4603.
    • (2005) Oncogene , vol.24 , pp. 4597-4603
    • Radhika, V.1    Hee Ha, J.2    Jayaraman, M.3    Tsim, S.T.4    Dhanasekaran, N.5
  • 34
    • 0034462185 scopus 로고    scopus 로고
    • Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1 -phosphate receptor EDG5 but not EDG1 or EDG3
    • Okamoto H, Takuwa N, Yokomizo T, Sugimoto N, Sakurada S, Shigematsu H, Takuwa Y. Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1 -phosphate receptor EDG5 but not EDG1 or EDG3. Mol Cell Biol. 2000;20:9247-9261.
    • (2000) Mol Cell Biol , vol.20 , pp. 9247-9261
    • Okamoto, H.1    Takuwa, N.2    Yokomizo, T.3    Sugimoto, N.4    Sakurada, S.5    Shigematsu, H.6    Takuwa, Y.7
  • 35
    • 0030033842 scopus 로고    scopus 로고
    • Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells
    • Sarkar R, Meinberg EG, Stanley JC, Gordon D, Webb RC. Nitric oxide reversibly inhibits the migration of cultured vascular smooth muscle cells. Circ Res. 1996;78:225-230.
    • (1996) Circ Res , vol.78 , pp. 225-230
    • Sarkar, R.1    Meinberg, E.G.2    Stanley, J.C.3    Gordon, D.4    Webb, R.C.5
  • 38
    • 22144463225 scopus 로고    scopus 로고
    • Okadaic acid induces phosphorylation and translocation of myosin phosphatase target subunit 1 influencing myosin phosphorylation, stress fiber assembly and cell migration in HepG2 cells
    • Lontay B, Kiss A, Gergely P, Hartshorne DJ, Erdodi F. Okadaic acid induces phosphorylation and translocation of myosin phosphatase target subunit 1 influencing myosin phosphorylation, stress fiber assembly and cell migration in HepG2 cells. Cell Signal. 2005;17:1265-1275.
    • (2005) Cell Signal , vol.17 , pp. 1265-1275
    • Lontay, B.1    Kiss, A.2    Gergely, P.3    Hartshorne, D.J.4    Erdodi, F.5
  • 39
    • 0037414792 scopus 로고    scopus 로고
    • Protein kinase A-mediated phosphorylation of the Galpha13 switch I region alters the Galphabetagamma13-G protein-coupled receptor complex and inhibits Rho activation
    • Manganello JM, Huang JS, Kozasa T, Voyno-Yasenetskaya TA, Le Breton GC. Protein kinase A-mediated phosphorylation of the Galpha13 switch I region alters the Galphabetagamma13-G protein-coupled receptor complex and inhibits Rho activation. J Biol Chem. 2003;278:124-130.
    • (2003) J Biol Chem , vol.278 , pp. 124-130
    • Manganello, J.M.1    Huang, J.S.2    Kozasa, T.3    Voyno-Yasenetskaya, T.A.4    Le Breton, G.C.5
  • 40
    • 0034712704 scopus 로고    scopus 로고
    • Nitric oxide modulates expression of cell cycle regulatory proteins: A cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation
    • Tanner FC, Meier P, Greutert H, Champion C, Nabel EG, Luscher TF. Nitric oxide modulates expression of cell cycle regulatory proteins: a cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation. Circulation. 2000;101:1982-1989.
    • (2000) Circulation , vol.101 , pp. 1982-1989
    • Tanner, F.C.1    Meier, P.2    Greutert, H.3    Champion, C.4    Nabel, E.G.5    Luscher, T.F.6
  • 43
    • 0033387969 scopus 로고    scopus 로고
    • eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity
    • Gurjar MV, Sharma RV, Bhalla RC. eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity. Arterioscler Thromb Vasc Biol. 1999;19:2871-2877.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2871-2877
    • Gurjar, M.V.1    Sharma, R.V.2    Bhalla, R.C.3
  • 45
    • 12844256402 scopus 로고    scopus 로고
    • The biology of cyclic GMP-dependent protein kinases
    • Hofmann F. The biology of cyclic GMP-dependent protein kinases. J Biol Chem. 2005;280:1-4.
    • (2005) J Biol Chem , vol.280 , pp. 1-4
    • Hofmann, F.1
  • 46
    • 35748984127 scopus 로고    scopus 로고
    • Regulation of RGS2 and second messenger signaling in vascular smooth muscle cells by cGMP-dependent protein kinase
    • Osei-Owusu P, Sun X, Drenan RM, Steinberg TH, Blumer KJ. Regulation of RGS2 and second messenger signaling in vascular smooth muscle cells by cGMP-dependent protein kinase. J Biol Chem. 2007;282:31656-31665.
    • (2007) J Biol Chem , vol.282 , pp. 31656-31665
    • Osei-Owusu, P.1    Sun, X.2    Drenan, R.M.3    Steinberg, T.H.4    Blumer, K.J.5
  • 48
  • 49
    • 0034862256 scopus 로고    scopus 로고
    • Invited review: CGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression
    • Lincoln TM, Dey N, Sellak H. Invited review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression. J Appl Physiol. 2001;91:1421-1430.
    • (2001) J Appl Physiol , vol.91 , pp. 1421-1430
    • Lincoln, T.M.1    Dey, N.2    Sellak, H.3
  • 50
    • 4544321243 scopus 로고    scopus 로고
    • Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides
    • Wooldridge AA, MacDonald JA, Erdodi F, Ma C, Borman MA, Hartshorne DJ, Haystead TA. Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides. J Biol Chem. 2004;279:34496-34504.
    • (2004) J Biol Chem , vol.279 , pp. 34496-34504
    • Wooldridge, A.A.1    MacDonald, J.A.2    Erdodi, F.3    Ma, C.4    Borman, M.A.5    Hartshorne, D.J.6    Haystead, T.A.7
  • 51
    • 34848854240 scopus 로고    scopus 로고
    • cGMP-dependent relaxation of smooth muscle is coupled with the change in the phosphorylation of myosin phosphatase
    • Nakamura K, Koga Y, Sakai H, Homma K, Ikebe M. cGMP-dependent relaxation of smooth muscle is coupled with the change in the phosphorylation of myosin phosphatase. Circ Res. 2007;101:712-722.
    • (2007) Circ Res , vol.101 , pp. 712-722
    • Nakamura, K.1    Koga, Y.2    Sakai, H.3    Homma, K.4    Ikebe, M.5
  • 52
    • 14644426000 scopus 로고    scopus 로고
    • Receptors coupled to heterotrimeric G proteins of the G12 family
    • Riobo NA, Manning DR. Receptors coupled to heterotrimeric G proteins of the G12 family. Trends Pharmacol Sci. 2005;26:146-154.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 146-154
    • Riobo, N.A.1    Manning, D.R.2
  • 54
    • 0037465793 scopus 로고    scopus 로고
    • Insulin-stimulated cyclic guanosine monophosphate inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulin-dependent protein kinase II
    • Zhang S, Yang Y, Kone BC, Allen JC, Kahn AM. Insulin-stimulated cyclic guanosine monophosphate inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulin-dependent protein kinase II. Circulation. 2003;107:1539-1544.
    • (2003) Circulation , vol.107 , pp. 1539-1544
    • Zhang, S.1    Yang, Y.2    Kone, B.C.3    Allen, J.C.4    Kahn, A.M.5
  • 55
    • 0033612371 scopus 로고    scopus 로고
    • Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration
    • Seasholtz TM, Majumdar M, Kaplan DD, Brown JH. Rho and Rho kinase mediate thrombin-stimulated vascular smooth muscle cell DNA synthesis and migration. Circ Res. 1999;84:1186-1193.
    • (1999) Circ Res , vol.84 , pp. 1186-1193
    • Seasholtz, T.M.1    Majumdar, M.2    Kaplan, D.D.3    Brown, J.H.4
  • 56
    • 33947715935 scopus 로고    scopus 로고
    • Mechanisms of vascular smooth muscle cell migration
    • Gerthoffer WT. Mechanisms of vascular smooth muscle cell migration. Circ Res. 2007;100:607-621.
    • (2007) Circ Res , vol.100 , pp. 607-621
    • Gerthoffer, W.T.1
  • 57
    • 33748652901 scopus 로고    scopus 로고
    • Dhanasekaran DN Transducing the signals: a G protein takes a new identity. Sci STKE. 2006;2006:pe31.
    • Dhanasekaran DN Transducing the signals: a G protein takes a new identity. Sci STKE. 2006;2006:pe31.


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