Redox-sensitive green fluorescent protein: Probes for dynamic intracellular redox responses. A review

Methods in Molecular Biology

Volumn 476, Issue , 2008, Pages 51-65

  Cannon, Mark B ^a   James Remington, S ^b  

^a BRIGHAM YOUNG UNIVERSITY HAWAII   (United States)

^b UNIVERSITY OF OREGON   (United States)

Author keywords

Biosensor; disulfide; GFP; midpoint potential; protein engineering; redox

Indexed keywords

ARABIDOPSIS;

GREEN FLUORESCENT PROTEIN;

ANIMAL; CHEMISTRY; GENETIC PROCEDURES; INTRACELLULAR SPACE; METABOLISM; MOLECULAR PROBE; OXIDATION REDUCTION REACTION; REVIEW;

ANIMALS; GREEN FLUORESCENT PROTEINS; INTRACELLULAR SPACE; MOLECULAR PROBE TECHNIQUES; MOLECULAR PROBES; OXIDATION-REDUCTION;

EID: 59249096240     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-59745-129-1_4     Document Type: Review

References (43)

1. Jacob, C., Knight, I., and Winyard, P. G. (2006) Aspects of the biological redox chemistry of cysteine: from simple redox responses to sophisticated signalling pathways. Biol Chem 387, 1385-1397. (Pubitemid 44691419)
2. Hwang, C., Sinskey, A. J., and Lodish, H. F. (1992) Oxidized redox state of glutathione in the endoplasmic reticulum. Science 257, 1496-1502.
3. Schafer, F. Q. and Buettner, G. R. (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med 30, 1191-1212. (Pubitemid 32463931)
4. Austin, C. D., Wen, X., Gazzard, L., Nelson, C., Scheller, R. H., and Scales, S. J. (2005) Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates. Proc Natl Acad Sci USA 102, 17987-17992. (Pubitemid 41798489)
5. Rhee, S. G., Chang, T. S., Bae, Y. S., Lee, S. R., and Kang, S. W. (2003) Cellular regulation by hydrogen peroxide. J Am Soc Nephrol 14, S211-S215. (Pubitemid 36903927)
6. Rhee, S. G., Bae, Y. S., Lee, S. R., and Kwon, J. (2000) Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci STKE 2000, PE1.
7. Ormo, M., Cubitt, A. B., Kallio, K., Gross, L. A., Tsien, R. Y., and Remington, S. J. (1996) Crystal structure of the Aequorea victoria green fluorescent protein. Science 273, 1392-1395. (Pubitemid 26296528)
8. Yang, F., Moss, L. G., and Phillips, G. N. J. (1996) The molecular structure of green fluorescent protein. Nat Biotechnol 14, 1246-1251. (Pubitemid 26332784)
9. Heim, R., Prasher, D. C., and Tsien, R. Y. (1994) Wavelength mutations and post-translational autoxidation of green fluorescent protein. Proc Natl Acad Sci USA 91, 12501-12504.
10. Baird, G. S., Zacharias, D. A., and Tsien, R. Y. (1999) Circular permutation and receptor insertion within green fluorescent proteins. Proc Natl Acad Sci USA 96, 11241-11246. (Pubitemid 29487365)
11. Tsien, R. Y. (1998) The green fluorescent protein. Annu Rev Biochem 67, 509-544. (Pubitemid 28411137)
12. Chattoraj, M., King, B. A., Bublitz, G. U., and Boxer, S. G. (1996) Ultra-fast excited state dynamics in green fluorescent protein: multiple states and proton transfer. Proc Natl Acad Sci USA 93, 8362-8367. (Pubitemid 26269563)
13. Brejc, K., Sixma, T. K., Kitts, P. A., Kain, S. R., Tsien, R. Y., Ormo, M., and Remington, S. J. (1997) Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein. Proc Natl Acad Sci USA 94, 2306-2311. (Pubitemid 27136870)
14. Palm, G. J., Zdanov, A., Gaitanaris, G. A., Stauber, R., Pavlakis, G. N., and Wlodawer, A. (1997) The structural basis for spectral variations in green fluorescent protein. Nat Struct Biol 4, 361-365.
15. Ward, W. W. and Bokman, S. H. (1982) Reversible denaturation of Aequorea green-fluorescent protein: physical separation and characterization of the renatured protein. Biochemistry 21, 4535-4540.
16. Ward, W. W., Prentice, H. J., Roth, A. F., Cody, C. W., and Reeves, S. C. (1982) Spectral perturbations of the Aequorea green-fluorescent protein. Photochem Photobiol 35, 803-808.
17. Giepmans, B. N., Adams, S. R., Ellisman, M. H., and Tsien, R. Y. (2006) The fluorescent protein toolbox for assessing protein location and function. Science 312, 217-223.
18. Zhang, J., Campbell, R. E., Ying, A. Y., and Tsien, R. Y. (2002) Creating new fluorescent probes for cell biology. Nat Rev Cell Biol 3, 906-918. (Pubitemid 35477369)
19. Grynkiewicz, G., Poenie, M., and Tsien, R.Y. (1985) A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 260, 3440-3450. (Pubitemid 15114340)
20. Hanson, G. T., Aggeler, R., Oglesbee, D., Cannon, M., Capaldi, R. A., Tsien, R. Y., and Remington, S. J. (2004) Investigating mitochondrial redox potential with redox-sensitive green fluorescent protein indicators. J Biol Chem 279, 13044-13053. (Pubitemid 38445882)
21. Rossignol, R., Gilkerson, R., Aggeler, R., Yamagata, K., Remington, S. J., and Capaldi, R. A. (2004) Energy substrate modulates mitochondrial structure and oxi-dative capacity in cancer cells. Cancer Res 64, 985-993. (Pubitemid 38176901)
22. Dooley, C. T., Dore, T. M., Hanson, G. T., Jackson, W. C., Remington, S. J., and Tsien, R. Y. (2004) Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators. J Biol Chem 279, 22284-22293. (Pubitemid 38679425)
23. Ostergaard, H., Henriksen, A., Hansen, F. G., and Winther, J. R. (2001) Shedding light on disulfide bond formation: engineering a redox switch in green fluorescent protein. EMBO J 20, 5853-5862. (Pubitemid 33049261)
24. Bjornberg, O., Ostergaard, H., and Winther, J. R. (2006) Measuring intracellular redox conditions using GFP-based sensors. Antioxid Redox Signal 8, 354-361. (Pubitemid 43741306)
25. Ostergaard, H., Tachibana, C., Winther, J. R. (2004) Monitoring disulfide bond formation in the eukaryotic cytosol. J Cell Biol 166, 337-345. (Pubitemid 39031237)
26. Rhee, S. G., Kang, S. W., Jeong, W., Chang, T. S., Yang, K. S., and Woo, H. A. (2005) Intracellular messenger function of hydrogen peroxide and its regulation by peroxire-doxins. Curr Opin Cell Biol 17, 183-189. (Pubitemid 40380942)
27. Finkel, T. (1998) Oxygen radicals and signaling. Curr Opin Cell Biol 10, 248-253. (Pubitemid 28174767)
28. Tu, B. P., Ho-Schleyer, S., Travers, K. J., and Weissman, J. S. (2000) Biochemical basis of oxidative protein folding in the endoplasmic reticulum. Science 290, 1571-1574.
29. Kim, J. R., Yoon, H.W., Kwon, K. S., Lee, S. R., and Rhee, S.G. (2000) Identification of proteins containing cysteine residues that are sensitive to oxidation by hydrogen peroxide at neutral pH. Ana. Biochem 283, 214-221. (Pubitemid 30626272)
30. Cannon, M. B., Remington, S. J. (2006) Re-engineering redox-sensitive green fluorescent protein for improved response rate. Protein Sci 15, 45-57. (Pubitemid 43004232)
31. Rocchia, W., Alexov, E., and Honig, B. (2001) Extending the applicability of the nonlinear Poisson-Boltzmann equation: multiple dielectric constants and multivalent ions. J Phys Chem B 105, 6507-6514. (Pubitemid 35339019)
32. Rocchia, W., Sridharan, S., Nicholls, A., Alexov, E., Chiabrera, A., and Honig, B. (2002) Rapid grid-based construction of the molecular surface for both molecules and geometric objects: applications to the finite difference Poisson-Boltzmann method. J Comp Chem 23, 128-137. (Pubitemid 34063137)
33. Hansen, R. E., Ostergaard, H., and Winther, J. R. (2005) Increasing the reactivity of an artificial dithiol-disulfide pair through modification of the electrostatic milieu. Biochemistry 44, 5899-5906. (Pubitemid 40525127)
34. Creighton, T. E. (1975) Interactions between cysteine residues as probes of protein conformation: the disulfide bond between Cys-14 and Cys-38 of the pancreatic trypsin inhibitor. J Mol Biol 96, 767-776.
35. Nelson, J. W. and Creighton, T. E. (1994) Reactivity and ionization of the active site cysteine residues of DsbA, a protein required for disulfide bond formation in vivo. Biochemistry 33, 5974-5983. (Pubitemid 24184604)
36. Jiang, K., Schwarzer, C., Lally, E., Zhang, S., Ruzin, S., Machen, T., Remington, S. J., and Feldman, L. (2006) Expression and characterization of a redox-sensing green fluorescent protein (reduction-oxidation-sensitive green fluorescent protein) in Arabidopsis. Plant Physiol 141, 397-403. (Pubitemid 43974534)
37. Joo, J. H., Bae, Y. S., and Lee, J. S. (2001) Role of auxin-induced reactive oxygen species in root gravitropism. Plant Physiol 126, 1055-1060.
38. Vesce, S., Jekabsons, M. B., Johnson-Caldwell, L. I., and Nicholls, D. G. (2005) Acute glutathione depletion restricts mitochondrial ATP export in cer-ebellar granule neurons. J Biol Chem 280, 38720-38728. (Pubitemid 43853775)
39. Calvete, J. A., Newell, D. R., Wright, A. F., and Rose, M. S. (1994) In vitro and in vivo antitumor activity of ZENECA ZD0490, a recombinant ricin A-chain immunotoxin for the treatment of colorectal cancer. Cancer Res 54, 4684-4690. (Pubitemid 24276495)
40. Liu, C., Tadayoni, B. M., Bourret, L. A., Mattocks, K. M., Derr, S. M., Widdison, W. C., Kedersha, N. L., Ariniello, P. D., Goldmacher, V. S., Lambert, J. M., Blattler, W. A., and Chari, R. V. (1996) Eradication of large colon tumor xenografts by targeted delivery of maytansinoids. Proc Natl Acad Sci USA 93, 8618-8623. (Pubitemid 26269609)
41. Austin, C. D., De Maziere, A. M., Pisa-cane, P. I., van Dijk, S. M., Eigenbrot, C., Sliwkowski, M. X., Klumperman, J., and Scheller, R. H. (2004) Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldan-amycin. Mol Biol Cell 15, 5268-5282. (Pubitemid 39564723)
42. Aslund, F. and Beckwith, J. (1999) The thioredoxin superfamily: redundancy, specificity and gray-area genomics. J Bacteriol 181, 1375-1379. (Pubitemid 29110793)
43. DeLano, W. L. (2002) The PyMOL Molecular Graphics System on World Wide Web: http://www.pymol.org.