메뉴 건너뛰기




Volumn 10, Issue 1, 2009, Pages 56-67

Conditional analyses on the T1DGC MHC dataset: Novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; HLA B ANTIGEN; HLA C ANTIGEN; HLA DPB1 ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA G ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 59149093630     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2008.74     Document Type: Article
Times cited : (32)

References (57)
  • 1
    • 34347389454 scopus 로고    scopus 로고
    • Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: A meta-analysis
    • Thomson G, Valdes AM, Noble JA, Kockum I, Grote MN, Najman J et al Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: A meta-analysis. Tissue Antigens 2007; 70: 110-127.
    • (2007) Tissue Antigens , vol.70 , pp. 110-127
    • Thomson, G.1    Valdes, A.M.2    Noble, J.A.3    Kockum, I.4    Grote, M.N.5    Najman, J.6
  • 2
    • 0023252262 scopus 로고
    • HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
    • Todd JA, Bell JI, McDevitt HO. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 1987; 329: 599-604.
    • (1987) Nature , vol.329 , pp. 599-604
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 4
    • 0029953008 scopus 로고    scopus 로고
    • The role of HLA class II genes in insulin-dependent diabetes mellitus: Molecular analysis of 180 Caucasian, multiplex families
    • Noble JA, Valdes AM, Cook M, Klitz W, Thomson G, Erlich HA. The role of HLA class II genes in insulin-dependent diabetes mellitus: Molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet 1996; 59: 1134-1148.
    • (1996) Am J Hum Genet , vol.59 , pp. 1134-1148
    • Noble, J.A.1    Valdes, A.M.2    Cook, M.3    Klitz, W.4    Thomson, G.5    Erlich, H.A.6
  • 8
    • 0033358374 scopus 로고    scopus 로고
    • The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene
    • Lie BA, Todd JA, Pociot F, Nerup J, Akselsen HE, Joner G et al. The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet 1999; 64: 793-800.
    • (1999) Am J Hum Genet , vol.64 , pp. 793-800
    • Lie, B.A.1    Todd, J.A.2    Pociot, F.3    Nerup, J.4    Akselsen, H.E.5    Joner, G.6
  • 9
    • 0033661271 scopus 로고    scopus 로고
    • Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B
    • Nejentsev S, Gombos Z, Laine AP, Veijola R, Knip M, Simell O et al Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B. Diabetes 2000; 49: 2217-2221.
    • (2000) Diabetes , vol.49 , pp. 2217-2221
    • Nejentsev, S.1    Gombos, Z.2    Laine, A.P.3    Veijola, R.4    Knip, M.5    Simell, O.6
  • 10
    • 36849012027 scopus 로고    scopus 로고
    • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
    • Nejentsev S, Howson JM, Walker NM, Szeszko J, Field SF, Stevens HE et al. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 2007; 450: 887-892.
    • (2007) Nature , vol.450 , pp. 887-892
    • Nejentsev, S.1    Howson, J.M.2    Walker, N.M.3    Szeszko, J.4    Field, S.F.5    Stevens, H.E.6
  • 11
    • 0035311823 scopus 로고    scopus 로고
    • Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci
    • Zavattari P, Lampis R, Motzo C, Loddo M, Mulargia A, Whalen M et al Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci. Hum Mol Genet 2001; 10 881-889.
    • (2001) Hum Mol Genet , vol.10 , pp. 881-889
    • Zavattari, P.1    Lampis, R.2    Motzo, C.3    Loddo, M.4    Mulargia, A.5    Whalen, M.6
  • 12
    • 0038643496 scopus 로고    scopus 로고
    • Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLADQB1, -DQA1 and -DRB1
    • Johansson S, Lie BA, Todd JA, Pociot F, Nerup J, Cambon-Thomsen A et al. Evidence of at least two type 1 diabetes susceptibility genes in the HLA complex distinct from HLADQB1, -DQA1 and -DRB1. Genes Immun 2003; 4: 46-53.
    • (2003) Genes Immun , vol.4 , pp. 46-53
    • Johansson, S.1    Lie, B.A.2    Todd, J.A.3    Pociot, F.4    Nerup, J.5    Cambon-Thomsen, A.6
  • 14
    • 20144388362 scopus 로고    scopus 로고
    • A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms
    • Miretti MM, Walsh EC, Ke X, Delgado M, Griffiths M, Hunt S et al. A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet 2005; 76: 634-646.
    • (2005) Am J Hum Genet , vol.76 , pp. 634-646
    • Miretti, M.M.1    Walsh, E.C.2    Ke, X.3    Delgado, M.4    Griffiths, M.5    Hunt, S.6
  • 15
    • 0042165029 scopus 로고    scopus 로고
    • Inheritable variable sizes of DNA stretches in the human MHC: Conserved extended haplotypes and their fragments or blocks
    • Yunis EJ, Larsen CE, Fernandez-Vina M, Awdeh ZL, Romero T, Hansen JA et al. Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocks. Tissue Antigens 2003; 62: 1-20.
    • (2003) Tissue Antigens , vol.62 , pp. 1-20
    • Yunis, E.J.1    Larsen, C.E.2    Fernandez-Vina, M.3    Awdeh, Z.L.4    Romero, T.5    Hansen, J.A.6
  • 18
    • 33745326638 scopus 로고    scopus 로고
    • Multi-SNP analysis of MHC region: Remarkable conservation of HLA-A1-B8-DR3 haplotype
    • Aly TA, Eller E, Ide A, Gowan K, Babu SR, Erlich HA et al. Multi-SNP analysis of MHC region: Remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes 2006; 55: 1265-1269.
    • (2006) Diabetes , vol.55 , pp. 1265-1269
    • Aly, T.A.1    Eller, E.2    Ide, A.3    Gowan, K.4    Babu, S.R.5    Erlich, H.A.6
  • 19
    • 33644761928 scopus 로고    scopus 로고
    • Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB1*03 and DRB1*04 haplotypes
    • Blomhoff A, Olsson M, Johansson S, Akselsen HE, Pociot F, Nerup J et al. Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB1*03 and DRB1*04 haplotypes. Genes Immun 2006; 7: 130-140.
    • (2006) Genes Immun , vol.7 , pp. 130-140
    • Blomhoff, A.1    Olsson, M.2    Johansson, S.3    Akselsen, H.E.4    Pociot, F.5    Nerup, J.6
  • 20
    • 0037444350 scopus 로고    scopus 로고
    • Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC
    • Ahmad T, Neville M, Marshall SE, Armuzzi A, Mulcahy-Hawes K, Crawshaw J et al. Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC. Hum Mol Genet 2003; 12 647-656.
    • (2003) Hum Mol Genet , vol.12 , pp. 647-656
    • Ahmad, T.1    Neville, M.2    Marshall, S.E.3    Armuzzi, A.4    Mulcahy-Hawes, K.5    Crawshaw, J.6
  • 22
    • 33846057724 scopus 로고    scopus 로고
    • NCBI reference sequences (RefSeq): A curated non-redundant sequence database of genomes, transcripts and proteins
    • database issue, D61-D65
    • Pruitt KD, Tatusova T, Maglott DR. NCBI reference sequences (RefSeq): A curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res 2007; 35 (database issue): D61-D65.
    • (2007) Nucleic Acids Res , vol.35
    • Pruitt, K.D.1    Tatusova, T.2    Maglott, D.R.3
  • 23
    • 19944433619 scopus 로고    scopus 로고
    • Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21
    • Nicolae D, Cox NJ, Lester LA, Schneider D, Tan Z, Billstrand C et al Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet 2005; 76: 349-357.
    • (2005) Am J Hum Genet , vol.76 , pp. 349-357
    • Nicolae, D.1    Cox, N.J.2    Lester, L.A.3    Schneider, D.4    Tan, Z.5    Billstrand, C.6
  • 25
    • 33745295348 scopus 로고    scopus 로고
    • The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G
    • Cirulli V, Zalatan J, McMaster M, Prinsen R, Salomon DR, Ricordi C et al. The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G. Diabetes 2006; 55: 1214-1222.
    • (2006) Diabetes , vol.55 , pp. 1214-1222
    • Cirulli, V.1    Zalatan, J.2    McMaster, M.3    Prinsen, R.4    Salomon, D.R.5    Ricordi, C.6
  • 26
  • 27
    • 15444367789 scopus 로고    scopus 로고
    • Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset
    • Valdes AM, Erlich HA, Noble JA. Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset. Hum Immunol 2005; 66: 301-313.
    • (2005) Hum Immunol , vol.66 , pp. 301-313
    • Valdes, A.M.1    Erlich, H.A.2    Noble, J.A.3
  • 28
    • 18544390541 scopus 로고    scopus 로고
    • The association of specific HLA class I and II alleles with type 1 diabetes among Filipinos
    • Bugawan TL, Klitz W, Alejandrino M, Ching J, Panelo A, Solfelix CM et al. The association of specific HLA class I and II alleles with type 1 diabetes among Filipinos. Tissue Antigens 2002; 59: 452-469.
    • (2002) Tissue Antigens , vol.59 , pp. 452-469
    • Bugawan, T.L.1    Klitz, W.2    Alejandrino, M.3    Ching, J.4    Panelo, A.5    Solfelix, C.M.6
  • 29
    • 43649103659 scopus 로고    scopus 로고
    • Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: Association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controls
    • Noble JA, Martin A, Valdes AM, Lane JA, Galgani A, Petrone A et al Type 1 diabetes risk for human leukocyte antigen (HLA)-DR3 haplotypes depends on genotypic context: Association of DPB1 and HLA class I loci among DR3- and DR4-matched Italian patients and controls. Hum Immunol 2008; 69: 291-300.
    • (2008) Hum Immunol , vol.69 , pp. 291-300
    • Noble, J.A.1    Martin, A.2    Valdes, A.M.3    Lane, J.A.4    Galgani, A.5    Petrone, A.6
  • 31
    • 0030587871 scopus 로고    scopus 로고
    • RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice
    • Kay TW, Parker JL, Stephens LA, Thomas HE, Allison J. RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice. J Immunol 1996; 157: 3688-3693.
    • (1996) J Immunol , vol.157 , pp. 3688-3693
    • Kay, T.W.1    Parker, J.L.2    Stephens, L.A.3    Thomas, H.E.4    Allison, J.5
  • 32
    • 0029783716 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived beta-cell cytotoxic CD8+ T-cell clones in vivo
    • Utsugi T, Yoon JW, Park BJ, Imamura M, Averill N, Kawazu S et al. Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived beta-cell cytotoxic CD8+ T-cell clones in vivo. Diabetes 1996; 45: 1121-1131.
    • (1996) Diabetes , vol.45 , pp. 1121-1131
    • Utsugi, T.1    Yoon, J.W.2    Park, B.J.3    Imamura, M.4    Averill, N.5    Kawazu, S.6
  • 33
    • 0028123012 scopus 로고
    • Prevention of insulitis and diabetes in beta 2-microglobulin-deficient non-obese diabetic mice
    • Sumida T, Furukawa M, Sakamoto A, Namekawa T, Maeda T, Zijlstra M et al. Prevention of insulitis and diabetes in beta 2-microglobulin-deficient non-obese diabetic mice. Int Immunol 1994; 6: 1445-1449.
    • (1994) Int Immunol , vol.6 , pp. 1445-1449
    • Sumida, T.1    Furukawa, M.2    Sakamoto, A.3    Namekawa, T.4    Maeda, T.5    Zijlstra, M.6
  • 34
    • 0027979956 scopus 로고
    • Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant
    • Serreze DV, Leiter EH, Christianson GJ, Greiner D, Roopenian DC. Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant. Diabetes 1994; 43: 505-509.
    • (1994) Diabetes , vol.43 , pp. 505-509
    • Serreze, D.V.1    Leiter, E.H.2    Christianson, G.J.3    Greiner, D.4    Roopenian, D.C.5
  • 36
    • 33749010061 scopus 로고    scopus 로고
    • Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in sweden
    • Roach JC, Deutsch K, Li S, Siegel AF, Bekris LM, Einhaus DC et al. Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in sweden. Am J Hum Genet 2006; 79: 614-627.
    • (2006) Am J Hum Genet , vol.79 , pp. 614-627
    • Roach, J.C.1    Deutsch, K.2    Li, S.3    Siegel, A.F.4    Bekris, L.M.5    Einhaus, D.C.6
  • 37
    • 42549143003 scopus 로고    scopus 로고
    • The association between type 1 diabetes and the ITPR3 gene polymorphism due to linkage disequilibrium with HLA class II
    • Qu HQ, Marchand L, Szymborski A, Grabs R, Polychronakos C. The association between type 1 diabetes and the ITPR3 gene polymorphism due to linkage disequilibrium with HLA class II. Genes Immun 2008; 9: 264-266.
    • (2008) Genes Immun , vol.9 , pp. 264-266
    • Qu, H.Q.1    Marchand, L.2    Szymborski, A.3    Grabs, R.4    Polychronakos, C.5
  • 39
    • 3242750623 scopus 로고    scopus 로고
    • DPB1 alleles are associated with type 1 diabetes susceptibility in multiple ethnic groups
    • Cruz TD, Valdes AM, Santiago A, Frazer de Llado T, Raffel LJ, Zeidler A et al. DPB1 alleles are associated with type 1 diabetes susceptibility in multiple ethnic groups. Diabetes 2004; 53: 2158-2163.
    • (2004) Diabetes , vol.53 , pp. 2158-2163
    • Cruz, T.D.1    Valdes, A.M.2    Santiago, A.3    Frazer de Llado, T.4    Raffel, L.J.5    Zeidler, A.6
  • 40
    • 0033985280 scopus 로고    scopus 로고
    • The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes
    • Noble JA, Valdes AM, Thomson G, Erlich HA. The HLA class II locus DPB1 can influence susceptibility to type 1 diabetes. Diabetes 2000; 49: 121-125.
    • (2000) Diabetes , vol.49 , pp. 121-125
    • Noble, J.A.1    Valdes, A.M.2    Thomson, G.3    Erlich, H.A.4
  • 42
    • 0035042697 scopus 로고    scopus 로고
    • The HLA-DPB1 - associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1
    • Cucca F, Dudbridge F, Loddo M, Mulargia AP, Lampis R, Angius E et al The HLA-DPB1 - associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1. Diabetes 2001; 50: 1200-1205.
    • (2001) Diabetes , vol.50 , pp. 1200-1205
    • Cucca, F.1    Dudbridge, F.2    Loddo, M.3    Mulargia, A.P.4    Lampis, R.5    Angius, E.6
  • 43
    • 34548461747 scopus 로고    scopus 로고
    • HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population
    • Baschal EE, Aly TA, Babu SR, Fernando MS, Yu L, Miao D et al. HLA-DPB1*0402 protects against type 1A diabetes autoimmunity in the highest risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY population. Diabetes 2007; 56: 2405-2409.
    • (2007) Diabetes , vol.56 , pp. 2405-2409
    • Baschal, E.E.1    Aly, T.A.2    Babu, S.R.3    Fernando, M.S.4    Yu, L.5    Miao, D.6
  • 44
    • 0030698020 scopus 로고    scopus 로고
    • HLA associations in insulin-dependent diabetes mellitus: No independent association to particular DP genes
    • Lie BA, Akselsen HE, Joner G, Dahl-Jorgensen K, Ronningen KS, Thorsby E et al. HLA associations in insulin-dependent diabetes mellitus: No independent association to particular DP genes. Hum Immunol 1997; 55: 170-175.
    • (1997) Hum Immunol , vol.55 , pp. 170-175
    • Lie, B.A.1    Akselsen, H.E.2    Joner, G.3    Dahl-Jorgensen, K.4    Ronningen, K.S.5    Thorsby, E.6
  • 45
    • 0037515739 scopus 로고    scopus 로고
    • HLA associations in type 1 diabetes: DPB1 alleles may act as markers of other HLA-complex susceptibility genes
    • Johansson S, Lie BA, Pociot F, Nerup J, Cambon-Thomsen A, Kockum I et al. HLA associations in type 1 diabetes: DPB1 alleles may act as markers of other HLA-complex susceptibility genes. Tissue Antigens 2003; 61: 344-351.
    • (2003) Tissue Antigens , vol.61 , pp. 344-351
    • Johansson, S.1    Lie, B.A.2    Pociot, F.3    Nerup, J.4    Cambon-Thomsen, A.5    Kockum, I.6
  • 46
    • 38349100266 scopus 로고    scopus 로고
    • Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project
    • Horton R, Gibson R, Coggill P, Miretti M, Allcock RJ, Almeida J et al Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project. Immunogenetics 2008; 60: 1-18.
    • (2008) Immunogenetics , vol.60 , pp. 1-18
    • Horton, R.1    Gibson, R.2    Coggill, P.3    Miretti, M.4    Allcock, R.J.5    Almeida, J.6
  • 47
    • 1842483890 scopus 로고    scopus 로고
    • Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, genegene and gene-environment interactions, and parent-of-origin effects
    • Cordell HJ, Barratt BJ, Clayton DG. Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, genegene and gene-environment interactions, and parent-of-origin effects. Genet Epidemiol 2004; 26: 167-185.
    • (2004) Genet Epidemiol , vol.26 , pp. 167-185
    • Cordell, H.J.1    Barratt, B.J.2    Clayton, D.G.3
  • 48
    • 3042653185 scopus 로고    scopus 로고
    • Maximum-likelihood estimation of haplotype frequencies in nuclear families
    • Becker T, Knapp M. Maximum-likelihood estimation of haplotype frequencies in nuclear families. Genet Epidemiol 2004; 27: 21-32.
    • (2004) Genet Epidemiol , vol.27 , pp. 21-32
    • Becker, T.1    Knapp, M.2
  • 49
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • The International HapMap Consortium
    • The International HapMap Consortium. The International HapMap Project. Nature 2003; 426: 789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 50
    • 0032231941 scopus 로고    scopus 로고
    • PedCheck: A program for identification of genotype incompatibilities in linkage analysis
    • O'Connell JR, Weeks DE. PedCheck: A program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 1998; 63: 259-266.
    • (1998) Am J Hum Genet , vol.63 , pp. 259-266
    • O'Connell, J.R.1    Weeks, D.E.2
  • 51
    • 0031024575 scopus 로고    scopus 로고
    • HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection
    • Undlien DE, Friede T, Rammensee HG, Joner G, Dahl-Jorgensen K, Sovik O et al. HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection. Diabetes 1997; 46: 143-149.
    • (1997) Diabetes , vol.46 , pp. 143-149
    • Undlien, D.E.1    Friede, T.2    Rammensee, H.G.3    Joner, G.4    Dahl-Jorgensen, K.5    Sovik, O.6
  • 52
    • 24044550689 scopus 로고    scopus 로고
    • PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
    • Wigginton JE, Abecasis GR. PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data. Bioinformatics 2005; 21: 3445-3447.
    • (2005) Bioinformatics , vol.21 , pp. 3445-3447
    • Wigginton, J.E.1    Abecasis, G.R.2
  • 53
  • 54
    • 0041857847 scopus 로고    scopus 로고
    • Pedigree disequilibrium tests for multilocus haplotypes
    • Dudbridge F. Pedigree disequilibrium tests for multilocus haplotypes. Genet Epidemiol 2003; 25: 115-121.
    • (2003) Genet Epidemiol , vol.25 , pp. 115-121
    • Dudbridge, F.1
  • 55
    • 0036137030 scopus 로고    scopus 로고
    • A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: Application to HLA in type 1 diabetes
    • Cordell HJ, Clayton DG. A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: Application to HLA in type 1 diabetes. Am J Hum Genet 2002; 70: 124-141.
    • (2002) Am J Hum Genet , vol.70 , pp. 124-141
    • Cordell, H.J.1    Clayton, D.G.2
  • 56
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 57
    • 0034017850 scopus 로고    scopus 로고
    • GOLD - graphical overview of linkage disequilibrium
    • Abecasis GR, Cookson WO. GOLD - graphical overview of linkage disequilibrium. Bioinformatics 2000; 16: 182-183.
    • (2000) Bioinformatics , vol.16 , pp. 182-183
    • Abecasis, G.R.1    Cookson, W.O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.