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Volumn 7, Issue 2, 2009, Pages 339-346

Molecular basis of platelet activation by an αIIbβ3-CHAMPS peptide

Author keywords

IIb 3 integrin; CHAMPS peptide; Platelets; Signal transduction; Tyrosine kinases

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADENOSINE DIPHOSPHATE; FC RECEPTOR; FORMALDEHYDE; INTEGRIN; INTEGRIN ACTIVATORY PEPTIDE; PROTEIN KINASE SYK; THROMBOXANE A2; TYROSINE; UNCLASSIFIED DRUG;

EID: 59049107360     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2008.03228.x     Document Type: Article
Times cited : (4)

References (23)
  • 2
    • 14844346910 scopus 로고    scopus 로고
    • Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering
    • Luo BH, Carman CV, Takagi J, Springer TA. Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering. Proc Natl Acad Sci U S A 2005;102: 3679-84.
    • (2005) Proc Natl Acad Sci U S , vol.102 , pp. 3679-3684
    • Luo, B.H.1    Carman, C.V.2    Takagi, J.3    Springer, T.A.4
  • 3
    • 16644396938 scopus 로고    scopus 로고
    • A specific interface between integrin transmembrane helices and affinity for ligand
    • Luo BH, Springer TA, Takagi J. A specific interface between integrin transmembrane helices and affinity for ligand. PLoS Biol 2004; 2: E153.
    • (2004) PLoS Biol , vol.2
    • Luo, B.H.1    Springer, T.A.2    Takagi, J.3
  • 4
    • 14844323604 scopus 로고    scopus 로고
    • Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state
    • Partridge AW, Liu S, Kim S, Bowie JU, Ginsberg MH. Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state. J Biol Chem 2005; 280: 7294-300.
    • (2005) J Biol Chem , vol.280 , pp. 7294-7300
    • Partridge, A.W.1    Liu, S.2    Kim, S.3    Bowie, J.U.4    Ginsberg, M.H.5
  • 5
    • 34948882323 scopus 로고    scopus 로고
    • Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling
    • Zhu J, Carman CV, Kim M, Shimaoka M, Springer TA, Luo BH. Requirement of alpha and beta subunit transmembrane helix separation for integrin outside-in signaling. Blood 2007; 110: 2475-83.
    • (2007) Blood , vol.110 , pp. 2475-2483
    • Zhu, J.1    Carman, C.V.2    Kim, M.3    Shimaoka, M.4    Springer, T.A.5    Luo, B.H.6
  • 7
    • 37549029679 scopus 로고    scopus 로고
    • Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo
    • Nieswandt B, Moser M, Pleines I, Varga-Szabo D, Monkley S, Critchley D, Fassler R. Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo. J Exp Med 2007; 204: 3113-8.
    • (2007) J Exp Med , vol.204 , pp. 3113-3118
    • Nieswandt, B.1    Moser, M.2    Pleines, I.3    Varga-Szabo, D.4    Monkley, S.5    Critchley, D.6    Fassler, R.7
  • 8
    • 34547654194 scopus 로고    scopus 로고
    • The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation
    • Petrich BG, Fogelstrand P, Partridge AW, Yousefi N, Ablooglu AJ, Shattil SJ, Ginsberg MH. The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation. J Clin Invest 2007; 117: 2250-9.
    • (2007) J Clin Invest , vol.117 , pp. 2250-2259
    • Petrich, B.G.1    Fogelstrand, P.2    Partridge, A.W.3    Yousefi, N.4    Ablooglu, A.J.5    Shattil, S.J.6    Ginsberg, M.H.7
  • 11
    • 40449133970 scopus 로고    scopus 로고
    • Kindlin-3 is essential for integrin activation and platelet aggregation
    • Moser M, Nieswandt B, Ussar S, Pozgajova M, Fassler R. Kindlin-3 is essential for integrin activation and platelet aggregation. Nat Med 2008; 14: 325-30.
    • (2008) Nat Med , vol.14 , pp. 325-330
    • Moser, M.1    Nieswandt, B.2    Ussar, S.3    Pozgajova, M.4    Fassler, R.5
  • 13
    • 11144223241 scopus 로고    scopus 로고
    • Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen
    • Pearce AC, Senis YA, Billadeau DD, Turner M, Watson SP, Vigorito E. Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen. J Biol Chem 2004; 279: 53955-62.
    • (2004) J Biol Chem , vol.279 , pp. 53955-53962
    • Pearce, A.C.1    Senis, Y.A.2    Billadeau, D.D.3    Turner, M.4    Watson, S.P.5    Vigorito, E.6
  • 14
    • 0037092048 scopus 로고    scopus 로고
    • Coordinate interactions of Csk Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton
    • Obergfell A, Eto K, Mocsai A, Buensuceso C, Moores SL, Brugge JS, Lowell CA, Shattil SJ. Coordinate interactions of Csk Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. J Cell Biol 2002; 157: 265-75.
    • (2002) J Cell Biol , vol.157 , pp. 265-275
    • Obergfell, A.1    Eto, K.2    Mocsai, A.3    Buensuceso, C.4    Moores, S.L.5    Brugge, J.S.6    Lowell, C.A.7    Shattil, S.J.8
  • 15
    • 0037294478 scopus 로고    scopus 로고
    • Thrombin-induced conversion of fibrinogen to fibrin results in rapid platelet trapping which is not dependent on platelet activation or GPIb
    • Jarvis GE, Atkinson BT, Frampton J, Watson SP. Thrombin-induced conversion of fibrinogen to fibrin results in rapid platelet trapping which is not dependent on platelet activation or GPIb. Br J Pharmacol 2003; 138: 574-83.
    • (2003) Br J Pharmacol , vol.138 , pp. 574-583
    • Jarvis, G.E.1    Atkinson, B.T.2    Frampton, J.3    Watson, S.P.4
  • 16
    • 0141733167 scopus 로고    scopus 로고
    • A critical role for phospholipase Cgamma2 in alphaIIbbeta3-mediated platelet spreading
    • Wonerow P, Pearce AC, Vaux DJ, Watson SP. A critical role for phospholipase Cgamma2 in alphaIIbbeta3-mediated platelet spreading. J Biol Chem 2003; 278: 37520-9.
    • (2003) J Biol Chem , vol.278 , pp. 37520-37529
    • Wonerow, P.1    Pearce, A.C.2    Vaux, D.J.3    Watson, S.P.4
  • 18
    • 1542284643 scopus 로고    scopus 로고
    • The heptapeptide LSARLAF mediates platelet activation through phospholipase Cgamma2 independently of glycoprotein IIb-IIIa
    • Pearce AC, Wonerow P, Marshall SJ, Frampton J, Gartner TK, Watson SP. The heptapeptide LSARLAF mediates platelet activation through phospholipase Cgamma2 independently of glycoprotein IIb-IIIa. Biochem J 2004; 378: 193-9.
    • (2004) Biochem J , vol.378 , pp. 193-199
    • Pearce, A.C.1    Wonerow, P.2    Marshall, S.J.3    Frampton, J.4    Gartner, T.K.5    Watson, S.P.6
  • 19
    • 0035760288 scopus 로고    scopus 로고
    • C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination
    • Tulasne D, Judd BA, Johansen M, Asazuma N, Best D, Brown EJ, Kahn M, Koretzky GA, Watson SP. C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination. Blood 2001; 98: 3346-52.
    • (2001) Blood , vol.98 , pp. 3346-3352
    • Tulasne, D.1    Judd, B.A.2    Johansen, M.3    Asazuma, N.4    Best, D.5    Brown, E.J.6    Kahn, M.7    Koretzky, G.A.8    Watson, S.P.9
  • 20
    • 0027414023 scopus 로고
    • Identification of a new cell adhesion motif in two homologous peptides from the COOH-terminal cell binding domain of human thrombospondin
    • Kosfeld MD, Frazier WA. Identification of a new cell adhesion motif in two homologous peptides from the COOH-terminal cell binding domain of human thrombospondin. J Biol Chem 1993; 268: 8808-14.
    • (1993) J Biol Chem , vol.268 , pp. 8808-8814
    • Kosfeld, M.D.1    Frazier, W.A.2
  • 21
    • 0029862392 scopus 로고    scopus 로고
    • Thrombospondin modulates alpha v beta 3 function through integrin-associated protein
    • Gao AG, Lindberg FP, Dimitry JM, Brown EJ, Frazier WA. Thrombospondin modulates alpha v beta 3 function through integrin-associated protein. J Cell Biol 1996; 135: 533-44.
    • (1996) J Cell Biol , vol.135 , pp. 533-544
    • Gao, A.G.1    Lindberg, F.P.2    Dimitry, J.M.3    Brown, E.J.4    Frazier, W.A.5
  • 22
    • 0030790357 scopus 로고    scopus 로고
    • The peptide LSARLAF causes platelet secretion and aggregation by directly activating the integrin alphaIIbbeta3
    • Derrick JM, Taylor DB, Loudon RG, Gartner TK. The peptide LSARLAF causes platelet secretion and aggregation by directly activating the integrin alphaIIbbeta3. Biochem J 1997; 325 (Pt 2): 309-13.
    • (1997) Biochem J , vol.325 , Issue.PART 2 , pp. 309-313
    • Derrick, J.M.1    Taylor, D.B.2    Loudon, R.G.3    Gartner, T.K.4
  • 23
    • 0038356580 scopus 로고    scopus 로고
    • The C-terminal peptide of thrombospondin-1 stimulates distinct signaling pathways but induces an activation-independent agglutination of platelets and other cells
    • Voit S, Udelhoven M, Lill G, Aktas B, Nieswandt B, Schror K, Weber AA. The C-terminal peptide of thrombospondin-1 stimulates distinct signaling pathways but induces an activation-independent agglutination of platelets and other cells. FEBS Lett 2003; 544: 240-5.
    • (2003) FEBS Lett , vol.544 , pp. 240-245
    • Voit, S.1    Udelhoven, M.2    Lill, G.3    Aktas, B.4    Nieswandt, B.5    Schror, K.6    Weber, A.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.