Protein kinase Cδ negatively regulates hedgehog signaling by inhibition of Gli1 activity

Journal of Biological Chemistry

Volumn 284, Issue 4, 2009, Pages 2150-2158

  Cai, Qingsong ^a,b   Li, Jing ^a,b   Gao, Tianyan ^a,b   Xie, Jingwu ^a,b   Evers, B Mark ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL GROWTH; GROWTH KINETICS; ONCOLOGY; TUMORS;

CELL LINES; CELL-CYCLE ARRESTS; CONSTITUTIVELY ACTIVES; EXPRESSION LEVELS; HEDGEHOG SIGNALING; HEPATOCELLULAR CARCINOMATA; HUMAN HEPATOMAS; HUMAN MALIGNANCIES; NEGATIVE REGULATORS; PHORBOL 12 MYRISTATE 13 ACETATES; PROTEIN KINASE C; TARGET GENES; TRANSCRIPTIONAL ACTIVITIES; TUMORIGENESIS; WILD TYPES;

SIGNALING;

PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN PATCHED 1; SMALL INTERFERING RNA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; GLI1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADULT; AGED; ANIMAL CELL; ARTICLE; CELL GROWTH; CELL STRAIN 3T3; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE TARGETING; HEPATOMA CELL; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; ACTIVE TRANSPORT; ANIMAL; CELL LINE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; REPORTER GENE; SIGNAL TRANSDUCTION;

ERINACEIDAE;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE; DOWN-REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HEDGEHOG PROTEINS; HUMANS; MICE; PROTEIN KINASE C-DELTA; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 59049104614     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803235200     Document Type: Article

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