-
1
-
-
0025912301
-
Tolerance to organic nitrates: evidence, mechanisms, clinical relevance, and strategies for prevention
-
Elkayam U. Tolerance to organic nitrates: evidence, mechanisms, clinical relevance, and strategies for prevention. Ann. Intern. Med. 114 (1991) 667-677
-
(1991)
Ann. Intern. Med.
, vol.114
, pp. 667-677
-
-
Elkayam, U.1
-
2
-
-
0023857352
-
A reappraisal of nitrate therapy
-
Abrams J. A reappraisal of nitrate therapy. J. Am. Med. Assoc. 259 (1988) 396-401
-
(1988)
J. Am. Med. Assoc.
, vol.259
, pp. 396-401
-
-
Abrams, J.1
-
3
-
-
0025316693
-
Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells
-
Chung S.J., and Fung H.L. Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells. J. Pharmacol. Exp. Ther. 253 2 (1990) 614-619
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.253
, Issue.2
, pp. 614-619
-
-
Chung, S.J.1
Fung, H.L.2
-
4
-
-
0025114810
-
Tolerance to intravenous nitroglycerin in patients with congestive heart failure: role of increased intravascular volume, neurohumoral activation and lack of prevention with N-acetylcysteine
-
Dupuis J., Lalonde G., Lemieux R., and Rouleau J.L. Tolerance to intravenous nitroglycerin in patients with congestive heart failure: role of increased intravascular volume, neurohumoral activation and lack of prevention with N-acetylcysteine. J. Am. Coll. Cardiol. 16 4 (1990) 923-931
-
(1990)
J. Am. Coll. Cardiol.
, vol.16
, Issue.4
, pp. 923-931
-
-
Dupuis, J.1
Lalonde, G.2
Lemieux, R.3
Rouleau, J.L.4
-
5
-
-
0023240541
-
Prevention and reversal of nitrate tolerance in patients with congestive heart failure
-
Packer M., Lee W.H., Kessler P.D., Gottlieb S.S., Medina N., and Yushak M. Prevention and reversal of nitrate tolerance in patients with congestive heart failure. N. Engl. J. Med. 317 13 (1987) 799-804
-
(1987)
N. Engl. J. Med.
, vol.317
, Issue.13
, pp. 799-804
-
-
Packer, M.1
Lee, W.H.2
Kessler, P.D.3
Gottlieb, S.S.4
Medina, N.5
Yushak, M.6
-
6
-
-
0025747926
-
Counter-regulatory responses to continuous and intermittent therapy with nitroglycerin
-
Parker J.D., Farrell B., Fenton T., Cohanim M., and Parker J.O. Counter-regulatory responses to continuous and intermittent therapy with nitroglycerin. Circulation 84 6 (1991) 2336-2345
-
(1991)
Circulation
, vol.84
, Issue.6
, pp. 2336-2345
-
-
Parker, J.D.1
Farrell, B.2
Fenton, T.3
Cohanim, M.4
Parker, J.O.5
-
7
-
-
0023525972
-
Effect of in vivo nitroglycerin therapy on endothelium-dependent and independent vascular relaxation and cyclic GMP accumulation in rat aorta
-
Molina C.R., Andresen J.W., Rapoport R.M., Waldman S., and Murad F. Effect of in vivo nitroglycerin therapy on endothelium-dependent and independent vascular relaxation and cyclic GMP accumulation in rat aorta. J. Cardiovasc. Pharm. 10 4 (1987) 371-378
-
(1987)
J. Cardiovasc. Pharm.
, vol.10
, Issue.4
, pp. 371-378
-
-
Molina, C.R.1
Andresen, J.W.2
Rapoport, R.M.3
Waldman, S.4
Murad, F.5
-
8
-
-
0020614041
-
Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover
-
Axelsson K.L., and Andersson R.G. Tolerance towards nitroglycerin, induced in vivo, is correlated to a reduced cGMP response and an alteration in cGMP turnover. Eur. J. Pharmacol. 88 1 (1983) 71-79
-
(1983)
Eur. J. Pharmacol.
, vol.88
, Issue.1
, pp. 71-79
-
-
Axelsson, K.L.1
Andersson, R.G.2
-
9
-
-
0024211427
-
Desensitization of guanylate cyclase in nitrate tolerance does not impair endothelium-dependent responses
-
Mulsch A., Busse R., and Bassenge E. Desensitization of guanylate cyclase in nitrate tolerance does not impair endothelium-dependent responses. Eur. J. Pharmacol. 158 3 (1988) 191-198
-
(1988)
Eur. J. Pharmacol.
, vol.158
, Issue.3
, pp. 191-198
-
-
Mulsch, A.1
Busse, R.2
Bassenge, E.3
-
10
-
-
26244465889
-
Explaining the phenomenon of nitrate tolerance
-
Munzel T., Daiber A., and Mulsch A. Explaining the phenomenon of nitrate tolerance. Circ. Res. 97 7 (2005) 618-628
-
(2005)
Circ. Res.
, vol.97
, Issue.7
, pp. 618-628
-
-
Munzel, T.1
Daiber, A.2
Mulsch, A.3
-
11
-
-
0028799761
-
Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance
-
Munzel T., Sayegh H., Freeman B.A., Tarpey M.M., and Harrison D.G. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. J. Clin. Invest. 95 1 (1995) 187-194
-
(1995)
J. Clin. Invest.
, vol.95
, Issue.1
, pp. 187-194
-
-
Munzel, T.1
Sayegh, H.2
Freeman, B.A.3
Tarpey, M.M.4
Harrison, D.G.5
-
12
-
-
0027242030
-
Hypercholesterolemia increases endothelial superoxide anion production
-
Ohara Y., Peterson T.E., and Harrison D.G. Hypercholesterolemia increases endothelial superoxide anion production. J. Clin. Invest. 91 6 (1993) 2546-2551
-
(1993)
J. Clin. Invest.
, vol.91
, Issue.6
, pp. 2546-2551
-
-
Ohara, Y.1
Peterson, T.E.2
Harrison, D.G.3
-
13
-
-
0034614284
-
Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability
-
Munzel T., Li H., Mollnau H., Hink U., Matheis E., Hartmann M., Oelze M., Skatchkov M., Warnholtz A., Duncker L., Meinertz T., and Forstermann U. Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability. Circ. Res. 86 1 (2000) E7-E12
-
(2000)
Circ. Res.
, vol.86
, Issue.1
-
-
Munzel, T.1
Li, H.2
Mollnau, H.3
Hink, U.4
Matheis, E.5
Hartmann, M.6
Oelze, M.7
Skatchkov, M.8
Warnholtz, A.9
Duncker, L.10
Meinertz, T.11
Forstermann, U.12
-
14
-
-
0028078872
-
Superoxide and peroxynitrite in atherosclerosis
-
White C.R., Brock T.A., Chang L.Y., Crapo J., Briscoe P., Ku D., Bradley W.A., Gianturco S.H., Gore J., Freeman B.A., and Tarpey M.M. Superoxide and peroxynitrite in atherosclerosis. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 1044-1048
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 1044-1048
-
-
White, C.R.1
Brock, T.A.2
Chang, L.Y.3
Crapo, J.4
Briscoe, P.5
Ku, D.6
Bradley, W.A.7
Gianturco, S.H.8
Gore, J.9
Freeman, B.A.10
Tarpey, M.M.11
-
15
-
-
0022353721
-
Erythrocyte aldehyde dehydrogenase and disulfiram-like side effects of hypoglycemics and antianginals
-
Towell J., Garthwaite T., and Wang R. Erythrocyte aldehyde dehydrogenase and disulfiram-like side effects of hypoglycemics and antianginals. Alcohol. Clin. Exp. Res. 9 5 (1985) 438-442
-
(1985)
Alcohol. Clin. Exp. Res.
, vol.9
, Issue.5
, pp. 438-442
-
-
Towell, J.1
Garthwaite, T.2
Wang, R.3
-
16
-
-
0037062518
-
Identification of the enzymatic mechanism of nitroglycerin bioactivation
-
Chen Z., Zhang J., and Stamler J.S. Identification of the enzymatic mechanism of nitroglycerin bioactivation. Proc. Natl. Acad. Sci. U.S.A. 99 12 (2002) 8306-8311
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, Issue.12
, pp. 8306-8311
-
-
Chen, Z.1
Zhang, J.2
Stamler, J.S.3
-
17
-
-
24744461677
-
An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation
-
Chen Z., Foster M.W., Zhang J., Mao L., Rockman H.A., Kawamoto T., Kitagawa K., Nakayama K.I., Hess D.T., and Stamler J.S. An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. Proc. Natl. Acad. Sci. U.S.A. 102 34 (2005) 12159-12164
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, Issue.34
, pp. 12159-12164
-
-
Chen, Z.1
Foster, M.W.2
Zhang, J.3
Mao, L.4
Rockman, H.A.5
Kawamoto, T.6
Kitagawa, K.7
Nakayama, K.I.8
Hess, D.T.9
Stamler, J.S.10
-
18
-
-
33847152178
-
Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice
-
Wenzel P., Hink U., Oelze M., Seeling A., Isse T., Bruns K., Steinhoff L., Brandt M., Kleschyov A.L., Schulz E., Lange K., Weiner H., Lehmann J., Lackner K.J., Kawamoto T., Munzel T., and Daiber A. Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice. Br. J. Pharmacol. 150 (2007) 526-533
-
(2007)
Br. J. Pharmacol.
, vol.150
, pp. 526-533
-
-
Wenzel, P.1
Hink, U.2
Oelze, M.3
Seeling, A.4
Isse, T.5
Bruns, K.6
Steinhoff, L.7
Brandt, M.8
Kleschyov, A.L.9
Schulz, E.10
Lange, K.11
Weiner, H.12
Lehmann, J.13
Lackner, K.J.14
Kawamoto, T.15
Munzel, T.16
Daiber, A.17
-
19
-
-
11144354818
-
Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance
-
Sydow K., Daiber A., Oelze M., Chen Z., August M., Wendt M., Ullrich V., Mulsch A., Schulz E., Keaney Jr. J.F., Stamler J.S., and Munzel T. Central role of mitochondrial aldehyde dehydrogenase and reactive oxygen species in nitroglycerin tolerance and cross-tolerance. J. Clin. Invest. 113 3 (2004) 482-489
-
(2004)
J. Clin. Invest.
, vol.113
, Issue.3
, pp. 482-489
-
-
Sydow, K.1
Daiber, A.2
Oelze, M.3
Chen, Z.4
August, M.5
Wendt, M.6
Ullrich, V.7
Mulsch, A.8
Schulz, E.9
Keaney Jr., J.F.10
Stamler, J.S.11
Munzel, T.12
-
20
-
-
33846969562
-
Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity: implications for mitochondrial oxidative stress and nitrate tolerance
-
Wenzel P., Hink U., Oelze M., Schuppan S., Schaeuble K., Schildknecht S., Ho K.K., Weiner H., Bachschmid M., Munzel T., and Daiber A. Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity: implications for mitochondrial oxidative stress and nitrate tolerance. J. Biol. Chem. 282 1 (2007) 792-799
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.1
, pp. 792-799
-
-
Wenzel, P.1
Hink, U.2
Oelze, M.3
Schuppan, S.4
Schaeuble, K.5
Schildknecht, S.6
Ho, K.K.7
Weiner, H.8
Bachschmid, M.9
Munzel, T.10
Daiber, A.11
-
21
-
-
33750024221
-
Bioactivation of nitroglycerin by the mitochondrial aldehyde dehydrogenase
-
Chen Z., and Stamler J.S. Bioactivation of nitroglycerin by the mitochondrial aldehyde dehydrogenase. Trends Cardiovasc. Med. 16 8 (2006) 259-265
-
(2006)
Trends Cardiovasc. Med.
, vol.16
, Issue.8
, pp. 259-265
-
-
Chen, Z.1
Stamler, J.S.2
-
22
-
-
9444221430
-
Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates
-
Daiber A., Oelze M., Coldewey M., Bachschmid M., Wenzel P., Sydow K., Wendt M., Kleschyov A.L., Stalleicken D., Ullrich V., Mulsch A., and Munzel T. Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates. Mol. Pharmacol. 66 6 (2004) 1372-1382
-
(2004)
Mol. Pharmacol.
, vol.66
, Issue.6
, pp. 1372-1382
-
-
Daiber, A.1
Oelze, M.2
Coldewey, M.3
Bachschmid, M.4
Wenzel, P.5
Sydow, K.6
Wendt, M.7
Kleschyov, A.L.8
Stalleicken, D.9
Ullrich, V.10
Mulsch, A.11
Munzel, T.12
-
23
-
-
33846969562
-
Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity. Implications for mitochondrial oxidative stress and nitrate tolerance
-
Wenzel P., Hink U., Oelze M., Schuppan S., Schaeuble K., Schildknecht S., Ho K.K., Weiner H., Bachschmid M., Munzel T., and Daiber A. Role of reduced lipoic acid in the redox regulation of mitochondrial aldehyde dehydrogenase (ALDH-2) activity. Implications for mitochondrial oxidative stress and nitrate tolerance. J. Biol. Chem. 282 1 (2007) 792-799
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.1
, pp. 792-799
-
-
Wenzel, P.1
Hink, U.2
Oelze, M.3
Schuppan, S.4
Schaeuble, K.5
Schildknecht, S.6
Ho, K.K.7
Weiner, H.8
Bachschmid, M.9
Munzel, T.10
Daiber, A.11
-
24
-
-
49649123367
-
Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases
-
Beretta M., Gruber K., Kollau A., Russwurm M., Koesling D., Goessler W., Keung W.M., Schmidt K., and Mayer B. Bioactivation of nitroglycerin by purified mitochondrial and cytosolic aldehyde dehydrogenases. J. Biol. Chem. 283 26 (2008) 17873-17880
-
(2008)
J. Biol. Chem.
, vol.283
, Issue.26
, pp. 17873-17880
-
-
Beretta, M.1
Gruber, K.2
Kollau, A.3
Russwurm, M.4
Koesling, D.5
Goessler, W.6
Keung, W.M.7
Schmidt, K.8
Mayer, B.9
-
25
-
-
48749090964
-
The role of lipoic acid in prevention of nitroglycerin tolerance
-
Dudek M., Bednarski M., Bilska A., Iciek M., Sokolowska-Jezewicz M., Filipek B., and Wlodek L. The role of lipoic acid in prevention of nitroglycerin tolerance. Eur. J. Pharmacol. 591 1-3 (2008) 203-210
-
(2008)
Eur. J. Pharmacol.
, vol.591
, Issue.1-3
, pp. 203-210
-
-
Dudek, M.1
Bednarski, M.2
Bilska, A.3
Iciek, M.4
Sokolowska-Jezewicz, M.5
Filipek, B.6
Wlodek, L.7
-
26
-
-
34248639600
-
Enzyme inhibition by peroxynitrite-mediated tyrosine nitration and thiol oxidation
-
Daiber A., and Bachschmid M. Enzyme inhibition by peroxynitrite-mediated tyrosine nitration and thiol oxidation. Curr. Enzyme Inhib. 3 (2007) 103-117
-
(2007)
Curr. Enzyme Inhib.
, vol.3
, pp. 103-117
-
-
Daiber, A.1
Bachschmid, M.2
-
27
-
-
0013887461
-
Effects of organic nitrates on mitochondrial respiration and swelling: possible correlations with the mechanism of pharmacologic action
-
Needleman P., and Hunter Jr. F.E. Effects of organic nitrates on mitochondrial respiration and swelling: possible correlations with the mechanism of pharmacologic action. Mol. Pharmacol. 2 2 (1966) 134-143
-
(1966)
Mol. Pharmacol.
, vol.2
, Issue.2
, pp. 134-143
-
-
Needleman, P.1
Hunter Jr., F.E.2
-
28
-
-
0015828822
-
Sulfhydryl reactivity of organic nitrates: biochemical basis for inhibition of glyceraldehyde-P dehydrogenase and monoamine oxidase
-
Jakschik B., and Needleman P. Sulfhydryl reactivity of organic nitrates: biochemical basis for inhibition of glyceraldehyde-P dehydrogenase and monoamine oxidase. Biochem. Biophys. Res. Commun. 53 2 (1973) 539-544
-
(1973)
Biochem. Biophys. Res. Commun.
, vol.53
, Issue.2
, pp. 539-544
-
-
Jakschik, B.1
Needleman, P.2
-
29
-
-
0015713177
-
Sulfhydryl requirement for relaxation of vascular smooth muscle
-
Needleman P., Jakschik B., and Johnson Jr. E.M. Sulfhydryl requirement for relaxation of vascular smooth muscle. J. Pharmacol. Exp. Ther. 187 2 (1973) 324-331
-
(1973)
J. Pharmacol. Exp. Ther.
, vol.187
, Issue.2
, pp. 324-331
-
-
Needleman, P.1
Jakschik, B.2
Johnson Jr., E.M.3
-
30
-
-
27844580204
-
Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure
-
Daiber A., Oelze M., Coldewey M., Kaiser K., Huth C., Schildknecht S., Bachschmid M., Nazirisadeh Y., Ullrich V., Mulsch A., Munzel T., and Tsilimingas N. Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation for its beneficial effects on prognosis in patients with congestive heart failure. Biochem. Biophys. Res. Commun. 338 4 (2005) 1865-1874
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, Issue.4
, pp. 1865-1874
-
-
Daiber, A.1
Oelze, M.2
Coldewey, M.3
Kaiser, K.4
Huth, C.5
Schildknecht, S.6
Bachschmid, M.7
Nazirisadeh, Y.8
Ullrich, V.9
Mulsch, A.10
Munzel, T.11
Tsilimingas, N.12
-
31
-
-
36448970474
-
Oxidative inhibition of the mitochondrial aldehyde dehydrogenase promotes nitroglycerin tolerance in human blood vessels
-
Hink U., Daiber A., Kayhan N., Trischler J., Kraatz C., Oelze M., Mollnau H., Wenzel P., Vahl C.F., Ho K.K., Weiner H., and Munzel T. Oxidative inhibition of the mitochondrial aldehyde dehydrogenase promotes nitroglycerin tolerance in human blood vessels. J. Am. Coll. Cardiol. 50 23 (2007) 2226-2232
-
(2007)
J. Am. Coll. Cardiol.
, vol.50
, Issue.23
, pp. 2226-2232
-
-
Hink, U.1
Daiber, A.2
Kayhan, N.3
Trischler, J.4
Kraatz, C.5
Oelze, M.6
Mollnau, H.7
Wenzel, P.8
Vahl, C.F.9
Ho, K.K.10
Weiner, H.11
Munzel, T.12
-
32
-
-
34547636112
-
Heme oxygenase-1: a novel key player in the development of tolerance in response to organic nitrates
-
Wenzel P., Oelze M., Coldewey M., Hortmann M., Seeling A., Hink U., Mollnau H., Stalleicken D., Weiner H., Lehmann J., Li H., Forstermann U., Munzel T., and Daiber A. Heme oxygenase-1: a novel key player in the development of tolerance in response to organic nitrates. Arterioscler. Thromb. Vasc. Biol. 27 8 (2007) 1729-1735
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, Issue.8
, pp. 1729-1735
-
-
Wenzel, P.1
Oelze, M.2
Coldewey, M.3
Hortmann, M.4
Seeling, A.5
Hink, U.6
Mollnau, H.7
Stalleicken, D.8
Weiner, H.9
Lehmann, J.10
Li, H.11
Forstermann, U.12
Munzel, T.13
Daiber, A.14
-
33
-
-
23944518097
-
Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD +/-): a novel approach to assess the role of oxidative stress for the development of nitrate tolerance
-
Daiber A., Oelze M., Sulyok S., Coldewey M., Schulz E., Treiber N., Hink U., Mulsch A., Scharffetter-Kochanek K., and Munzel T. Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD +/-): a novel approach to assess the role of oxidative stress for the development of nitrate tolerance. Mol. Pharmacol. 68 3 (2005) 579-588
-
(2005)
Mol. Pharmacol.
, vol.68
, Issue.3
, pp. 579-588
-
-
Daiber, A.1
Oelze, M.2
Sulyok, S.3
Coldewey, M.4
Schulz, E.5
Treiber, N.6
Hink, U.7
Mulsch, A.8
Scharffetter-Kochanek, K.9
Munzel, T.10
-
34
-
-
44049088536
-
First evidence for a crosstalk between mitochondrial and NADPH oxidase-derived reactive oxygen species in nitroglycerin-triggered vascular dysfunction
-
Wenzel P., Mollnau H., Oelze M., Schulz E., Wickramanayake J.M., Muller J., Schuhmacher S., Hortmann M., Baldus S., Gori T., Brandes R.P., Munzel T., and Daiber A. First evidence for a crosstalk between mitochondrial and NADPH oxidase-derived reactive oxygen species in nitroglycerin-triggered vascular dysfunction. Antioxid Redox Signal 10 8 (2008) 1435-1447
-
(2008)
Antioxid Redox Signal
, vol.10
, Issue.8
, pp. 1435-1447
-
-
Wenzel, P.1
Mollnau, H.2
Oelze, M.3
Schulz, E.4
Wickramanayake, J.M.5
Muller, J.6
Schuhmacher, S.7
Hortmann, M.8
Baldus, S.9
Gori, T.10
Brandes, R.P.11
Munzel, T.12
Daiber, A.13
-
35
-
-
41949104144
-
Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction
-
Doughan A.K., Harrison D.G., and Dikalov S.I. Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction. Circ. Res. 102 4 (2008) 488-496
-
(2008)
Circ. Res.
, vol.102
, Issue.4
, pp. 488-496
-
-
Doughan, A.K.1
Harrison, D.G.2
Dikalov, S.I.3
-
36
-
-
54149096363
-
MnSOD ALDH-2 deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction
-
10.1093/cvr/cvn182
-
Wenzel P., Schuhmacher S., Kienhofer J., Muller J., Hortmann M., Oelze M., Schulz E., Treiber N., Kawamoto T., Scharffetter-Kochanek K., Munzel T., Burkle A., Bachschmid M.M., and Daiber A. MnSOD ALDH-2 deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. Cardiovasc. Res. (2008) 10.1093/cvr/cvn182
-
(2008)
Cardiovasc. Res.
-
-
Wenzel, P.1
Schuhmacher, S.2
Kienhofer, J.3
Muller, J.4
Hortmann, M.5
Oelze, M.6
Schulz, E.7
Treiber, N.8
Kawamoto, T.9
Scharffetter-Kochanek, K.10
Munzel, T.11
Burkle, A.12
Bachschmid, M.M.13
Daiber, A.14
-
37
-
-
38049088299
-
ALDH-2 deficiency increases cardiovascular oxidative stress-Evidence for indirect antioxidative properties
-
Wenzel P., Muller J., Zurmeyer S., Schuhmacher S., Schulz E., Oelze M., Pautz A., Kawamoto T., Wojnowski L., Kleinert H., Munzel T., and Daiber A. ALDH-2 deficiency increases cardiovascular oxidative stress-Evidence for indirect antioxidative properties. Biochem. Biophys. Res. Commun. 367 1 (2008) 137-143
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.367
, Issue.1
, pp. 137-143
-
-
Wenzel, P.1
Muller, J.2
Zurmeyer, S.3
Schuhmacher, S.4
Schulz, E.5
Oelze, M.6
Pautz, A.7
Kawamoto, T.8
Wojnowski, L.9
Kleinert, H.10
Munzel, T.11
Daiber, A.12
-
38
-
-
34249746904
-
Increased superoxide production in nitrate tolerance is associated with NAD(P)H oxidase and aldehyde dehydrogenase 2 downregulation
-
Szocs K., Lassegue B., Wenzel P., Wendt M., Daiber A., Oelze M., Meinertz T., Munzel T., and Baldus S. Increased superoxide production in nitrate tolerance is associated with NAD(P)H oxidase and aldehyde dehydrogenase 2 downregulation. J. Mol. Cell. Cardiol. 42 6 (2007) 1111-1118
-
(2007)
J. Mol. Cell. Cardiol.
, vol.42
, Issue.6
, pp. 1111-1118
-
-
Szocs, K.1
Lassegue, B.2
Wenzel, P.3
Wendt, M.4
Daiber, A.5
Oelze, M.6
Meinertz, T.7
Munzel, T.8
Baldus, S.9
-
39
-
-
0032861874
-
Long-term nitrate use may be deleterious in ischemic heart disease: a study using the databases from two large-scale postinfarction studies. Multicenter Myocardial Ischemia Research Group
-
Nakamura Y., Moss A.J., Brown M.W., Kinoshita M., and Kawai C. Long-term nitrate use may be deleterious in ischemic heart disease: a study using the databases from two large-scale postinfarction studies. Multicenter Myocardial Ischemia Research Group. Am. Heart J. 138 3 Pt 1 (1999) 577-585
-
(1999)
Am. Heart J.
, vol.138
, Issue.3 PART 1
, pp. 577-585
-
-
Nakamura, Y.1
Moss, A.J.2
Brown, M.W.3
Kinoshita, M.4
Kawai, C.5
-
40
-
-
33947501974
-
Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: evidence of a free radical mediated mechanism
-
Thomas G.R., DiFabio J.M., Tommaso T., and Parker J.D. Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: evidence of a free radical mediated mechanism. J. Am. Coll. Cardiol. 49 12 (2007) 1289-1295
-
(2007)
J. Am. Coll. Cardiol.
, vol.49
, Issue.12
, pp. 1289-1295
-
-
Thomas, G.R.1
DiFabio, J.M.2
Tommaso, T.3
Parker, J.D.4
-
41
-
-
0037066021
-
Functional biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatment
-
Schulz E., Tsilimingas N., Rinze R., Reiter B., Wendt M., Oelze M., Woelken-Weckmuller S., Walter U., Reichenspurner H., Meinertz T., and Munzel T. Functional biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatment. Circulation 105 10 (2002) 1170-1175
-
(2002)
Circulation
, vol.105
, Issue.10
, pp. 1170-1175
-
-
Schulz, E.1
Tsilimingas, N.2
Rinze, R.3
Reiter, B.4
Wendt, M.5
Oelze, M.6
Woelken-Weckmuller, S.7
Walter, U.8
Reichenspurner, H.9
Meinertz, T.10
Munzel, T.11
-
42
-
-
24144454139
-
Aldehyde dehydrogenase 2 plays a role in the bioactivation of nitroglycerin in humans
-
Mackenzie I.S., Maki-Petaja K.M., McEniery C.M., Bao Y.P., Wallace S.M., Cheriyan J., Monteith S., Brown M.J., and Wilkinson I.B. Aldehyde dehydrogenase 2 plays a role in the bioactivation of nitroglycerin in humans. Arterioscler. Thromb. Vasc. Biol. 25 9 (2005) 1891-1895
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, Issue.9
, pp. 1891-1895
-
-
Mackenzie, I.S.1
Maki-Petaja, K.M.2
McEniery, C.M.3
Bao, Y.P.4
Wallace, S.M.5
Cheriyan, J.6
Monteith, S.7
Brown, M.J.8
Wilkinson, I.B.9
-
43
-
-
32444440593
-
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin
-
Li Y., Zhang D., Jin W., Shao C., Yan P., Xu C., Sheng H., Liu Y., Yu J., Xie Y., Zhao Y., Lu D., Nebert D.W., Harrison D.C., Huang W., and Jin L. Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin. J. Clin. Invest. 116 2 (2006) 506-511
-
(2006)
J. Clin. Invest.
, vol.116
, Issue.2
, pp. 506-511
-
-
Li, Y.1
Zhang, D.2
Jin, W.3
Shao, C.4
Yan, P.5
Xu, C.6
Sheng, H.7
Liu, Y.8
Yu, J.9
Xie, Y.10
Zhao, Y.11
Lu, D.12
Nebert, D.W.13
Harrison, D.C.14
Huang, W.15
Jin, L.16
-
44
-
-
46749093300
-
Inhibition of aldehyde dehydrogenase type 2 attenuates vasodilatory action of nitroglycerin in human veins
-
Huellner M.W., Schrepfer S., Weyand M., Weiner H., Wimplinger I., Eschenhagen T., and Rau T. Inhibition of aldehyde dehydrogenase type 2 attenuates vasodilatory action of nitroglycerin in human veins. FASEB J. 22 7 (2008) 2561-2568
-
(2008)
FASEB J.
, vol.22
, Issue.7
, pp. 2561-2568
-
-
Huellner, M.W.1
Schrepfer, S.2
Weyand, M.3
Weiner, H.4
Wimplinger, I.5
Eschenhagen, T.6
Rau, T.7
-
45
-
-
0024312693
-
Aldehyde dehydrogenase from human erythrocytes: structural relationship to the liver cytosolic isozyme
-
Agarwal D.P., Cohn P., Goedde H.W., and Hempel J. Aldehyde dehydrogenase from human erythrocytes: structural relationship to the liver cytosolic isozyme. Enzyme 42 1 (1989) 47-52
-
(1989)
Enzyme
, vol.42
, Issue.1
, pp. 47-52
-
-
Agarwal, D.P.1
Cohn, P.2
Goedde, H.W.3
Hempel, J.4
-
46
-
-
0347318126
-
Measurement of NAD(P)H oxidase-derived superoxide with the luminol analogue L-012
-
Daiber A., August M., Baldus S., Wendt M., Oelze M., Sydow K., Kleschyov A.L., and Munzel T. Measurement of NAD(P)H oxidase-derived superoxide with the luminol analogue L-012. Free Radic. Biol. Med. 36 1 (2004) 101-111
-
(2004)
Free Radic. Biol. Med.
, vol.36
, Issue.1
, pp. 101-111
-
-
Daiber, A.1
August, M.2
Baldus, S.3
Wendt, M.4
Oelze, M.5
Sydow, K.6
Kleschyov, A.L.7
Munzel, T.8
-
47
-
-
38149029311
-
New insights into bioactivation of organic nitrates, nitrate tolerance and cross-tolerance
-
Daiber A., Wenzel P., Oelze M., and Munzel T. New insights into bioactivation of organic nitrates, nitrate tolerance and cross-tolerance. Clin. Res. Cardiol. 97 1 (2008) 12-20
-
(2008)
Clin. Res. Cardiol.
, vol.97
, Issue.1
, pp. 12-20
-
-
Daiber, A.1
Wenzel, P.2
Oelze, M.3
Munzel, T.4
|