Synthesis and preliminary antibacterial evaluation of simplified thiomarinol analogs

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 3, 2009, Pages 1006-1017

  Marion, Olivier ^a   Gao, Xuri ^a   Marcus, Sandra ^a   Hall, Dennis G ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Antibacterial; Cycloaddition allylboration tandem reaction; Mupirocin; Thiomarinol analogs

Indexed keywords

3,4 DIHYDROXY 5 (4 METHYL 5 HYDROXYHEX 2 ENYL)TETRAHYDROPYRAN 2 YL 3 METHYL 4 HYDROXYBUTYLENOYLOXYETHANE; 3,4 O ISOPROPYLIDENE 3,4 DIHYDROXY 5 (4 METHYL 5 TRIISOPROPYLSILYLOXYL HEX 2 ENYL]TETRAHYDROPYRAN 2 YL) 3 METHYL 4 TRIISOPROPYLSILYLOXYBUTYLENOIC ACID BUTYLAMIDE; AMIDE; ESTER DERIVATIVE; PSEUDOMONIC ACID; THIOMARINOL DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG DESIGN; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; NONHUMAN;

AMINO ACYL-TRNA SYNTHETASES; ANTI-BACTERIAL AGENTS; CYCLIZATION; DISK DIFFUSION ANTIMICROBIAL TESTS; MUPIROCIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 58949097887     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.01.001     Document Type: Article

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