The chemistry of pseudomonic acid. 17. Dual-action C-1 oxazole derivatives of pseudomonic acid having an extended spectrum of antibacterial activity

Journal of Medicinal Chemistry

Volumn 39, Issue 18, 1996, Pages 3596-3600

  Broom, Nigel J P ^a   Cassels, Robert ^a   Cheng, Hung Yuan ^c   Elder, John S ^a   Hannan, Peter C T ^a   Masson, Nicki ^a   O'Hanlon, Peter J ^a   Pope, Andrew ^b   Wilson, Jennifer M ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b The Frythe   (United Kingdom)

^c Physical and Structural Chemistry   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIINFECTIVE AGENT; ISOLEUCINE TRANSFER RNA LIGASE; NITROFURANTOIN; OXAZOLE DERIVATIVE; OXIDOREDUCTASE; PSEUDOMONIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SB 205952; UNCLASSIFIED DRUG; VANCOMYCIN;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; AREA UNDER THE CURVE; ARTICLE; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; INFECTION; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; STAPHYLOCOCCUS; SUBCUTANEOUS DRUG ADMINISTRATION;

ANTI-BACTERIAL AGENTS; BACTERIA; MUPIROCIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029820014     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950882q     Document Type: Article

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