Identification of a novel 5-HT4 receptor splice variant (r5-HT4c1) and preliminary characterisation of specific 5-HT4a and 5-HT4b receptor antibodies

European Journal of Pharmacology

Volumn 604, Issue 1-3, 2009, Pages 1-11

  Ray, Alison M ^a   Kelsell, Rosemary E ^a   Houp, Jennifer A ^a   Kelly, Fiona M ^a   Medhurst, Andrew D ^a   Cox, Helen M ^b   Calver, Andrew R ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

5 HT4 receptor; Novel splice variant; Selective antibody

Indexed keywords

MESSENGER RNA; PRUCALOPRIDE; RECEPTOR ANTIBODY; RENZAPRIDE; SEROTONIN 4 AGONIST; SEROTONIN 4 RECEPTOR; SEROTONIN 4A RECEPTOR; SEROTONIN 4B RECEPTOR; SEROTONIN 4C1 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN; COLON; DUODENUM; ENDOCRINE CELL; GASTROINTESTINAL TRACT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; JEJUNUM; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SATELLITE CELL; SPINAL GANGLION; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION;

ALTERNATIVE SPLICING; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; BINDING, COMPETITIVE; CELL LINE; CELL MEMBRANE; CLONING, MOLECULAR; CYCLIC AMP; FEMALE; GASTROINTESTINAL TRACT; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR SEQUENCE DATA; PROTEIN ISOFORMS; RABBITS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN, 5-HT4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEROTONIN AGONISTS; TRANSFECTION;

EID: 58949089378     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.11.056     Document Type: Article

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