Gastric dysreflexia after acute experimental spinal cord injury in rats

Neurogastroenterology and Motility

Volumn 21, Issue 2, 2009, Pages 197-206

  Tong, M ^a   Holmes, G M ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Gastric motility; Neurotrauma; Receptive relaxation reflex; Vagovagal reflex

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FOOD INTAKE; GASTROESOPHAGEAL REFLUX; MALE; NONHUMAN; PATHOLOGICAL REFLEX; PRIORITY JOURNAL; RAT; SPINAL CORD INJURY; STOMACH MOTILITY; STOMACH PARESIS; STRAIN GAUGE TRANSDUCER;

ANIMALS; AUTONOMIC DYSREFLEXIA; EATING; GANGLIA, SYMPATHETIC; GASTROINTESTINAL MOTILITY; GASTROPARESIS; HUMANS; MALE; MOTOR ACTIVITY; RANDOM ALLOCATION; RATS; RATS, WISTAR; REFLEX; SPINAL CORD INJURIES; STOMACH;

EID: 58849161413     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2008.01215.x     Document Type: Article

References (66)

1. Travagli RA, Hermann GE, Browning KN, Rogers RC. Brainstem circuits regulating gastric function. Annu Rev Physiol 2006 68 : 279 305.
2. Abrahamsson H. Studies on the inhibitory nervous control of gastric motility. Acta Physiol Scand Suppl 1973 390 : 1 38.
3. Abrahamsson H, Jansson G. Elicitation of reflex vagal relaxation of the stomach from pharynx and esophagus in the cat. Acta Physiol Scand 1969 77 : 172 8.
4. McCann MJ, Rogers RC. Impact of antral mechanoreceptor activation on the vago-vagal reflex in the rat: functional zonation of responses. J Physiol 1992 453 : 401 11.
5. McCann MJ, Rogers RC. Functional and Chemical Anatomy of a Gastric Vago-Vagal Reflex. In : Wingate DL, ed. Innervation of the Gut: Pathophysiological Implications. Boca Raton : CRC Press, 1994 : 81 92.
6. Gillis RA, Quest JA, Pagani FD, Norman WP. Control centers in the central nervous system for regulating gastrointestinal motility. Handbook of Physiology. The Gastrointestinal System. Motility and Circulation. Bethesda : American Physiological Society, 1989 : 621 83.
7. Krowicki ZK, Sivarao DV, Abrahams TP, Hornby PJ. Excitation of dorsal motor vagal neurons evokes non-nicotinic receptor-mediated gastric relaxation. J Auton Nerv Syst 1999 77 : 83 9.
8. Takahashi T, Owyang C. Characterization of vagal pathways mediating gastric accommodation reflex in rats. J Physiol 1997 504 (Pt 2 479 88.
9. Jansson G. Vago-vagal reflex relaxation of the stomach in the cat. Acta Physiol Scand 1969 75 : 245 52.
10. Rogers RC, McTigue DM, Hermann GE. Vagal control of digestion: modulation by central neural and peripheral endocrine factors. Neurosci Biobehav Rev 1996 20 : 57 66.
11. Travagli RA, Browning KN, Gillis RA. Studies of the dorsal motor nucleus of the vagus, a major CNS center for controlling vagal outflow to the upper gastrointestinal tract. In : Quigley EM, Pfeiffer RF, eds. Neurogastroenterology. Philadelphia : Butterworth-Heinemann, 2004.
12. Takahashi T, Owyang C. Vagal control of nitric oxide and vasoactive intestinal polypeptide release in the regulation of gastric relaxation in rat. J Physiol 1995 484 (Pt 2 481 92.
13. Hermann GE, Travagli RA, Rogers RC. Esophageal-gastric relaxation reflex in rat: dual control of peripheral nitrergic and cholinergic transmission. Am J Physiol Regul Integr Comp Physiol 2006 290 : R1570 6.
14. Kirshblum SC, Groah SL, McKinley WO, Gittler MS, Stiens SA. Spinal cord injury medicine. 1. Etiology, classification, and acute medical management. Arch Phys Med Rehabil 2002 3 (Suppl. 1 S50 8.
15. Wolf C, Meiners TH. Dysphagia in patients with acute cervical spinal cord injury. Spinal Cord 2003 41 : 347 53.
16. Dwyer KM, Watts DD, Thurber JS, Benoit RS, Fakhry SM. Percutaneous endoscopic gastrostomy: the preferred method of elective feeding tube placement in trauma patients. J Trauma 2002 52 : 26 32.
17. Oakley PA, Coleman NA, Morrison PJ. Intensive care of the trauma patient. Resuscitation 2001 48 : 37 46.
18. Cosman BC, Stone JM, Perkash I. Gastrointestinal complications of chronic spinal cord injury. J Am Paraplegia Soc 1991 14 : 175 81.
19. Berlly MH, Wilmot CB. Acute abdominal emergencies during the first four weeks after spinal cord injury. Arch Phys Med Rehabil 1984 65 : 687 90.
20. Fealey RD, Szurszewski JH, Merritt JL, DiMagno EP. Effect of traumatic spinal cord transection on human upper gastrointestinal motility and gastric emptying. Gastroenterology 1984 87 : 69 75.
21. Kao CH, Ho YJ, Changlai SP, Ding HJ. Gastric emptying in spinal cord injury patients. Dig Dis Sci 1999 44 : 1512 5.
22. Kewalramani LS. Neurogenic gastroduodenal ulceration and bleeding associated with spinal cord injuries. J Trauma 1979 19 : 259 65.
23. Nino-Murcia M, Friedland GW. Functional abnormalities of the gastrointestinal tract in patients with spinal cord injuries: Evaluation with imaging procedures. Am J Roentgenol 1991 158 : 279 81.
24. Rajendran SK, Reiser JR, Bauman W, Zhang RL, Gordon SK, Korsten MA. Gastrointestinal transit after spinal cord injury: Effect of cisapride. Am J Gastroenterol 1992 87 : 1614 7.
25. Segal JL, Milne N, Brunnemann SR. Gastric emptying is impaired in patients with spinal cord injury. Am J Gastroenterol 1995 90 : 466 70.
26. Stinneford JG, Keshavarzian A, Nemchausky BA, Doria MI, Durkin M. Esophagitis and esophageal motor abnormalities in patients with chronic spinal cord injuries. Paraplegia 1993 31 : 384 92.
27. Primeaux SD, Tong M, Holmes GM. Effects of chronic spinal cord injury on body weight and body composition in rats fed a standard chow diet. Am J Physiol Regul Integr Comp Physiol 2007 293 : R1102 9.
28. Gondim FA, de Alencar HM, Rodrigues M, da Graca L, dos Santos R, Rola FH. Complete cervical or thoracic spinal cord transections delay gastric emptying and gastrointestinal transit of liquid in awake rats. Spinal Cord 1999 37 : 793 9.
29. Kabatas S, Yu D, He XD et al. Neural and anatomical abnormalities of the gastrointestinal system resulting from contusion spinal cord injury. Neuroscience 2008 154 : 1627 38.
30. Krantis A, Mattar K, Glasgow I. Rat gastroduodenal motility in vivo: interaction of GABA and VIP in control of spontaneous relaxations. Am J Physiol Gastrointest Liver Physiol 1998 275 : G897 903.
31. Fukuda H, Tsuchida D, Koda K, Miyazaki M, Pappas TN, Takahashi T. Impaired gastric motor activity after abdominal surgery in rats. Neurogastroenterol Motil 2005 17 : 245 50.
32. Hermann GE, Rogers RC. Tumor necrosis factor-α in the dorsal vagal complex suppresses gastric motility. Neuroimmunomodulation 1995 2 : 74 81.
33. Canon WC, Lieb CW. The receptive relaxation of the stomach. Am J Physiol 1911 29 : 267 73.
34. Rogers RC, Hermann GE, Travagli RA. Brainstem pathways responsible for oesophageal control of gastric motility and tone in the rat. J Physiol 1999 514 (Pt 2 369 83.
35. Rogers RC, Travagli RA, Hermann GE. Noradrenergic neurons in the rat solitary nucleus participate in the esophageal-gastric relaxation reflex. Am J Physiol Regul Integr Comp Physiol 2003 285 : R479 89.
36. Sengupta JN. An overview of esophageal sensory receptors. Am J Med 2000 108 (Suppl. 4a 87S 9S.
37. Lu WY, Bieger D. Vagovagal reflex motility patterns of the rat esophagus. Am J Physiol Regul Integr Comp Physiol 1998 274 (5 Pt 2 R1425 35.
38. Lu WY, Bieger D. Vagal afferent transmission in the NTS mediating reflex responses of the rat esophagus. Am J Physiol Regul Integr Comp Physiol 1998 274 (5 Pt 2 R1436 45.
39. Holmes GM, Van Meter MJ, Bresnahan JC, Beattie MS. Serotonergic fiber sprouting to external anal sphincter motoneurons after spinal cord contusion. Exp Neurol 2005 193 : 29 42.
40. Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 1995 12 : 1 21.
41. Buelke-Sam J, Holson JF, Bazare JJ, Young JF. Comparative stability of physiological parameters during sustained anesthesia in rats. Lab Anim Sci 1978 28 : 157 62.
42. Rabchevsky AG, Fugaccia I, Turner AF, Blades DA, Mattson MP, Scheff SW. Basic fibroblast growth factor (bFGF) enhances functional recovery following severe spinal cord injury to the rat. Exp Neurol 2000 164 : 280 91.
43. Rabchevsky AG, Fugaccia I, Fletcher-Turner A, Blades DA, Mattson MP, Scheff SW. Basic fibroblast growth factor (bFGF) enhances tissue sparing and functional recovery following moderate spinal cord injury. J Neurotrauma 1999 16 : 817 30.
44. Ormsbee HS, Bass P. Gastroduodenal motor gradients in the dog after pyloroplasty. Am J Physiol 1976 230 : 389 97.
45. Bramlett HM, Dietrich WD. Progressive damage after brain and spinal cord injury: pathomechanisms and treatment strategies. Prog Brain Res 2007 161 : 125 41.
46. Zagon A, Smith AD. Monosynaptic projections from the rostral ventrolateral medulla oblongata to identified sympathetic preganglionic neurons. Neuroscience 1993 54 : 729 43.
47. Maiorov DN, Weaver LC, Krassioukov AV. Relationship between sympathetic activity and aterial pressure in conscious spinal rats. Am J Physiol Heart Circ Physiol 1997 272 : H625 31.
48. Roman C, Gonella J. Extrinsic control of digestive tract motility. In : Johnson LR, ed. Physiology of the Gastrointestinal Tract, 2 edn. New York : Raven Press, 1987 : 507 53.
49. Yamada M, Terayama R, Bando Y, Kasai S, Yoshida S. Regeneration of the abdominal postganglionic sympathetic system. Neurosci Res 2006 54 : 261 8.
50. Gondim FA, Rodrigues CL, da Graca JR et al. Neural mechanisms involved in the delay of gastric emptying and gastrointestinal transit of liquid after thoracic spinal cord transection in awake rats. Auton Neurosci 2001 87 : 52 8.
51. Weaver LC, Marsh DR, Gris D, Brown A, Dekaban GA. Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention. Prog Brain Res 2006 152 : 245 63.
52. Rabchevsky AG. Segmental organization of spinal reflexes mediating autonomic dysreflexia after spinal cord injury. Prog Brain Res 2005 152 : 265 74.
53. Laird AS, Carrive P, Waite PM. Cardiovascular and temperature changes in spinal cord injured rats at rest and during autonomic dysreflexia. J Physiol 2006 577 (Pt 2 539 48.
54. Leal PR, Cruz PR, Lopes AC Jr. et al. A new model of autonomic dysreflexia induced by gastric distension in the spinal cord-transected rat. Auton Neurosci 2008 141 : 66 72.
55. Sengupta JN, Kauvar D, Goyal RK. Characteristics of vagal esophageal tension-sensitive afferent fibers in the opossum. J Neurophysiol 1989 61 : 1001 10.
56. Euchner-Wamser I, Sengupta JN, Gebhart GF, Meller ST. Characterization of responses of T2-T4 spinal cord neurons to esophageal distension in the rat. J Neurophysiol 1993 69 : 868 83.
57. Qin C, Chandler MJ, Foreman RD. Afferent pathways and responses of T3-T4 spinal neurons to cervical and thoracic esophageal distensions in rats. Auton Neurosci 2003 109 : 10 20.
58. Leal PR, Lima RC Jr., Lopes AC Jr. et al. Haemodynamic changes after spinal cord transection are anaesthetic agent dependent. Auton Autacoid Pharmacol 2007 27 : 167 71.
59. Powley TL, Phillips RJ. Gastric satiation is volumetric, intestinal satiation is nutritive. Physiol Behav 2004 82 : 69 74.
60. Ozaki N, Gebhart GF. Characterization of mechanosensitive splanchnic nerve afferent fibers innervating the rat stomach. Am J Physiol Gastrointest Liver Physiol 2001 281 : G1449 59.
61. Neuhuber W, Niederle B. Spinal ganglion cells innervating the stomach of the rat as demonstrated by somatopetal transport of horseradish peroxidase (HRP). Anat Embryol (Berl) 1979 155 : 355 62.
62. Renehan WE, Zhang X, Beierwaltes WH, Fogel R. Neurons in the dorsal motor nucleus of the vagus may integrate vagal and spinal information from the GI tract. Am J Physiol Gastrointest Liver Physiol 1995 268 : G780 90.
63. Menetrey D, Basbaum AI. Spinal and trigeminal projections to the nucleus of the solitary tract: a possible substrate for somatovisceral and viscerovisceral reflex activation. J Comp Neurol 1987 255 : 439 50.
64. Menetrey D, de Pommery J. Origins of Spinal Ascending Pathways that Reach Central Areas Involved in Visceroception and Visceronociception in the Rat. Eur J Neurosci 1991 3 : 249 59.
65. Gamboa-Esteves FO, Tavares I, Almeida A, Batten TF, McWilliam PN, Lima D. Projection sites of superficial and deep spinal dorsal horn cells in the nucleus tractus solitarii of the rat. Brain Res 2001 921 : 195 205.
66. Medeiros BA, dos Santos CL, Palheta RC Jr. et al. Spinal cord transection modifies ileal fluid and electrolyte transport in rats. Auton Neurosci 2008 139 : 24 9.