Esophageal-gastric relaxation reflex in rat: Dual control of peripheral nitrergic and cholinergic transmission

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 290, Issue 6, 2006, Pages

  Hermann, Gerlinda E ^a   Travagli, R Alberto ^a   Rogers, Richard C ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Nonadrenergic, noncholinergic; Receptive relaxation reflex; Vagovagal reflex

Indexed keywords

ATROPINE METHYL NITRATE; N(G) NITROARGININE METHYL ESTER;

ANIMAL EXPERIMENT; ARTICLE; BALLOON DILATATION; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; DRUG MECHANISM; ESOPHAGUS DILATATION; MALE; NITRERGIC NERVE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ATROPINE; BETHANECHOL; CHOLINERGIC FIBERS; DEGLUTITION; ENZYME INHIBITORS; ESOPHAGUS; GANGLIONIC BLOCKERS; GASTRIC FUNDUS; GASTROINTESTINAL MOTILITY; HEXAMETHONIUM; MALE; MUSCARINIC AGONISTS; NG-NITROARGININE METHYL ESTER; NITRERGIC NEURONS; PARASYMPATHOLYTICS; PERIPHERAL NERVOUS SYSTEM; RATS; RATS, LONG-EVANS; REFLEX; STOMACH; VAGUS NERVE;

EID: 33744803438     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00717.2005     Document Type: Article

References (57)

1. Abrahamsson H. Studies on the inhibitory nervous control of gastric motility. Acta Physiol Scand Suppl 390: 1-38, 1973.
2. Altschuler SM, Bao XM, Bieger D, Hopkins DA, and Miselis RR. Viscerotopic representation of the upper alimentary tract in the rat: sensory ganglia and nuclei of the solitary and spinal trigeminal tracts. J Comp Neurol 283: 248-268, 1989.
3. Andrews PL, Grundy D, and Scratcherd T. Reflex excitation of antral motility induced by gastric distension in the ferret. J Physiol 298: 79-84, 1980.
4. Andrews PL, Grundy D, and Scratcherd T. Vagal afferent discharge from mechanoreceptors in different regions of the ferret stomach. J Physiol 298: 513-524, 1980.
5. Behrns KE and Sarr MG. Diagnosis and management of gastric emptying disorders. Adv Surg 27: 233-255, 1994.
6. Berthoud HR. Anatomical demonstration of vagal input to nicotinamide acetamide dinucleotide phosphate diaphorase-positive (nitrergic) neurons in rat fundic stomach. J Comp Neurol 358: 428-439, 1995.
7. Bieger D. The brainstem esophagomotor network pattern generator: a rodent model. Dysphagia 8: 203-208, 1993.
8. Bieger D. Rhombencephalic pathways and neurotransmitters controlling deglutition. Am J Med 111, Suppl 8A: 85S-89S, 2001.
9. Buelke-Sam J, Holson JF, Bazare JJ, and Young JF. Comparative stability of physiological parameters during sustained anesthesia in rats. Lab Anim Sci 28: 157-162, 1978.
10. Cannon WB and Leib CW. The receptive relaxation of the stomach. Am J Physiol 29: 267-273, 1911.
11. Cho CH, Qiu BS, Ballard HJ, and Ogle CW. Adenosine and cholinergic-induced gastric contraction in rats. Digestion 54: 98-104, 1993.
12. Dambrova M, Chlopicki S, Liepinsh E, Kirjanova O, Gorshkova O, Kozlovski VI, Uhlen S, Liepina I, Petrovska R, and Kalvinsh I. The methylester of γ-butyrobetaine, but not γ-butyrobetaine itself, induces muscarinic receptor-dependent vasodilatation. Naunyn Schmiedebergs Arch Pharmacol 369: 533-539, 2004.
13. Desai KM, Sessa WC, and Vane JR. Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid. Nature 351: 477-479, 1991.
14. Dong H, Loomis CW, and Bieger D. Vagal afferent input determines the volume dependence of rat esophageal motility patterns. Am J Physiol Gastrointest Liver Physiol 281: G44-G53, 2001.
15. Ferreira M Jr, Sahibzada N, Shi M, Niedringhaus M, Wester MR, Jones AR, Verbalis JG, and Gillis RA. Hindbrain chemical mediators of reflex-induced inhibition of gastric tone produced by esophageal distension and intravenous nicotine. Am J Physiol Regul Integr Comp Physiol 289: R1482-R1495, 2005.
16. Ferreira M Jr, Sahibzada N, Shi M, Panico W, Niedringhaus M, Wasserman A, Kellar KJ, Verbalis J, and Gillis RA. CNS site of action and brainstem circuitry responsible for the intravenous effects of nicotine on gastric tone. J Neurosci 22: 2764-2779, 2002.
17. Fukuda A, Minami T, Nabekura J, and Oomura Y. The effects of noradrenaline on neurones in the rat dorsal motor nucleus of the vagus, in vitro. J Physiol 393: 213-231, 1987.
18. Gillis RA, Quest JA, Pagani FD, and Norman WP. Control centers in the central nervous system for regulating gastrointestinal motility. In: Handbook of Physiology. The Gastrointestinal System. Motility and Circulation. Bethesda, MD: Am Physiol Soc, 1989, sect. 6, vol. I, p. 621-683.
19. Goyal RK, Padmanabhan R, and Sang Q. Neural circuits in swallowing and abdominal vagal afferent-mediated lower esophageal sphincter relaxation. Am J Med 111: 95S-105S, 2001.
20. Grundy D and Schemann M. Motor control of the stomach. In: Innervation of the Gastrointestinal Tract, edited by Brookes S and Costa M. London: Taylor and Francis, 2002, p. 57-102.
21. Hornby PJ. Receptors and transmission in the brain-gut axis. II. Excitatory amino acid receptors in the brain-gut axis. Am J Physiol Gastrointest Liver Physiol 280: G1055-G1060, 2001.
22. Jansson G. Vago-vagal reflex relaxation of the stomach in the cat. Acta Physiol Scand 75: 245-252, 1969.
23. Jean A. Brain stem control of swallowing: neuronal network and cellular mechanisms. Physiol Rev 81: 929-969, 2001.
24. Krowicki ZK, Nathan NA, and Hornby PJ. Gastric motor and cardiovascular effects of insulin in dorsal vagal complex of the rat. Am J Physiol Gastrointest Liver Physiol 275: G964-G972, 1998.
25. Krowicki ZK, Sharkey KA, Serron SC, Nathan NA, and Hornby PJ. Distribution of nitric oxide synthase in rat dorsal vagal complex and effects of microinjection of nitric oxide compounds upon gastric motor function. J Comp Neurol 377: 49-69, 1997.
26. Lee K and Mack GW. Role of nitric oxide in methacholine-induced sweating and vasodilation in human skin. J Appl Physiol October 20, 2005; doi:10.1152/japplphysiol.00122.2005.
27. G-nitro-L- arginine on non-adrenergic non-cholinergic relaxation in the guinea-pig gastric fundus. Br J Pharmacol 106: 173-179, 1992.
28. Lewis MW, Hermann GE, Rogers RC, and Travagli RA. In vitro and in vivo analysis of the effects of corticotropin releasing factor on rat dorsal vagal complex. J Physiol 543: 135-146, 2002.
29. Lu WY and Bieger D. Vagal afferent transmission in the NTS mediating reflex responses of the rat esophagus. Am J Physiol Regul Integr Comp Physiol 274: R1436-R1445, 1998.
30. Lu WY and Bieger D. Vagovagal reflex motility patterns of the rat esophagus. Am J Physiol Regul Integr Comp Physiol 274: R1425-R1435, 1998.
31. Martinez-Pena y Valenzuela I, Rogers RC, Hermann GE, and Travagli RA. Norepinephrine effects on identified neurons of the rat dorsal motor nucleus of the vagus. Am J Physiol Gastrointest Liver Physiol 286: G333-G339, 2004.
32. Mashimo H, Kjellin A, and Goyal RK. Gastric stasis in neuronal nitric oxide synthase-deficient knockout mice. Gastroenterology 119: 766-773, 2000.
33. McCann MJ and Rogers RC. Impact of antral mechanoreceptor activation on the vago-vagal reflex in the rat: functional zonation of responses. J Physiol 453: 401-411, 1992.
34. Millard P. Anesthetic procedures. In: Clinical Procedures in Veterinary Nursing (2nd ed.), edited by Aspinall V. London: Elsevier, 2003, p. 121-155.
35. Miolan JP and Roman C. Discharge of efferent vagal fibers supplying gastric antrum: indirect study by nerve suture technique. Am J Physiol Endocrinol Metab Gastrointest Physiol 235: E366-E373, 1978.
36. Miolan JP and Roman C. The role of oesophageal and intestinal receptors in the control of gastric motility. J Auton Nerv Syst 10: 235-241, 1984.
37. Rinaman L. Hindbrain noradrenergic lesions attenuate anorexia and alter central cFos expression in rats after gastric viscerosensory stimulation. J Neurosci 23: 10084-10092, 2003.
38. Rogers RC, Hermann GE, and Travagli RA. Brainstem control of gastric function. In: Physiology of the Gastrointestinal Tract (4th ed.), edited by Johnson LR. New York: Elsevier, 2005.
39. Rogers RC, Hermann GE, and Travagli RA. Brainstem pathways responsible for oesophageal control of gastric motility and tone in the rat. J Physiol 514: 369-383, 1999.
40. Rogers RC, Travagli RA, and Hermann GE. Brainstem catecholaminergic neurons are activated during the esophageal-gastric receptive relaxation reflex (Abstract). FASEB J 17: 605.3, 2003.
41. Rogers RC, Travagli RA, and Hermann GE. Noradrenergic neurons in the rat solitary nucleus participate in the esophageal-gastric relaxation reflex. Am J Physiol Regul Integr Comp Physiol 285: R479-R489, 2003.
42. Roman C and Gonella J. Extrinsic control of digestive tract motility. In: Physiology of the Gastrointestinal Tract (2nd ed.), edited by Johnson LR. New York: Raven, 1987, p. 507-553.
43. Sababi M and Nylander O. Comparative study of the effects of nitric oxide synthase and cyclo-oxygenase inhibition on duodenal functions in rats anaesthetized with Inactin, urethane or α-chloralose. Acta Physiol Scand 158: 45-52, 1996.
44. Schemann M and Grundy D. Electrophysiological identification of vagally innervated enteric neurons in guinea pig stomach. Am J Physiol Gastrointest Liver Physiol 263: G709-G718, 1992.
45. Sengupta JN. An overview of esophageal sensory receptors. Am J Med 108, Suppl 4a: 87S-89S, 2000.
46. Sengupta JN, Kauvar D, and Goyal RK. Characteristics of vagal esophageal tension-sensitive afferent fibers in the opossum. J Neurophysiol 61: 1001-1010, 1989.
47. Sengupta JN, Petersen J, Peles S, and Shaker R. Response properties of antral mechanosensitive afferent fibers and effects of ionotropic glutamate receptor antagonists. Neuroscience 125: 711-723, 2004.
48. Silverman J and Muir WW III. A review of laboratory animal anesthesia with chloral hydrate and chloralose. Lab Anim Sci 43: 210-216, 1993.
49. Smith BN, Dou P, Barber WD, and Dudek FE. Vagally evoked synaptic currents in the immature rat nucleus tractus solitarii in an intact in vitro preparation. J Physiol 512: 149-162, 1998.
50. Takahashi T and Owyang C. Characterization of vagal pathways mediating gastric accommodation reflex in rats. J Physiol 504: 479-488, 1997.
51. Takahashi T and Owyang C. Vagal control of nitric oxide and vasoactive intestinal polypeptide release in the regulation of gastric relaxation in rat. J Physiol 484: 481-492, 1995.
52. Travagli RA, Hermann GE, Browning KN, and Rogers RC. Brainstem circuits regulating gastric function. Annu Rev Physiol 68: 279-305, 2005.
53. Travagli RA, Hermann GE, Browning KN, and Rogers RC. Musings on the wanderer: what's new in our understanding of vago-vagal reflexes? III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach. Am J Physiol Gastrointest Liver Physiol 284: G180-G187, 2003.
54. Travagli RA and Rogers RC. Receptors and transmission in the brain-gut axis: potential for novel therapies. V. Fast and slow extrinsic modulation of dorsal vagal complex circuits. Am J Physiol Gastrointest Liver Physiol 281: G595-G601, 2001.
55. Travers JB, Dinardo LA, and Karimnamazi H. Motor and premotor mechanisms of licking. Neurosci Biobehav Rev 21: 631-647, 1997.
56. Travers SP and Norgren R. Organization of orosensory responses in the nucleus of the solitary tract of rat. J Neurophysiol 73: 2144-2162, 1995.
57. Zheng ZL, Rogers RC, and Travagli RA. Selective gastric projections of nitric oxide synthase containing vagal brainstem neurones. Neuroscience 90: 685-694, 1999.