Relationship between sympathetic activity and arterial pressure in conscious spinal rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 272, Issue 2 41-2, 1997, Pages

  Maiorov, Dmitri N ^a   Weaver, Lynne C ^a   Krassioukov, Andrei V ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

autonomic dysreflexia; cardiovascular regulation; spinal cord injury

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; HYPERTENSION; NONHUMAN; PATHOPHYSIOLOGY; PRESSORECEPTOR; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SPINAL ANIMAL; SPINAL CORD INJURY; SPINAL CORD TRANSSECTION; SPINAL REFLEX; SYMPATHETIC TONE;

EID: 33750862630     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1997.272.2.h625     Document Type: Article

References (33)

1. Ardell, J. L., S. M. Barman, and G. L. Gebber. Sympathetic nerve discharge in chronic spinal cat. Am. J. Physiol. 243 (Heart Circ. Physiol. 12): H463-H470, 1982.
2. Arnold, J. M. O., G. A. Delaney, Q. P. Feng, and R. W. Teasell. Alpha adrenoreceptor hyper-responsivness in quadriplegic patients with autonomic dysreflexia. Clin. Auton. Res. 5: 267-270, 1995.
3. Calaresu, F. R., and C. P. Yardley. Medullary basal sympathetic tone. Annu. Rev. Physiol. 50: 511-524, 1988.
4. Chiou-Tan, F. Y., M. L. Lenz, C. S. Robertson, and M. Grabois. Pharmacologic treatment of autonomic dysreflexia in the rat. Am. J. Phys. Med. Rehab. 73: 251-255, 1994.
5. Coote, J. H., C. B. B. Downman, and W. V. Weber. Reflex discharges into thoracic white rami elicited by somatic and visceral afferent excitation. J. Physiol. Lond. 202: 147-159, 1969.
6. Dembowsky, K. Integrative properties of sympathetic preganglionic neurones within the thoracic spinal cord. Clin. Exp. Hypertens. 17: 313-321, 1995.
7. Dembowsky, K., J. Czachurski, K. Amendt, and H. Seller. Tonic descending inhibition of the spinal somato-sympathetic reflex from the lower brain stem. J. Auton. Nerv. Sys. 2: 157-182, 1980.
8. Donald, D. E. Splanchnic circulation. In: Handbook of Physiology. The Cardiovascular System. Peripheral Circulation and Organ Blood Flow. Bethesda, MD: Am. Physiol. Soc., 1983, sect. 2, vol. III, pt. 1, chapt. 7, p. 219-240.
9. Erickson, R. P. Autonomic hyperreflexia: pathophysiology and medical management. Arch. Physiol. Med. Rehab. 61: 431-440, 1980.
10. Gootman, P. M., and M. I. Cohen. Sympathetic rhythms in spinal cats. J. Auton. Nerv. Sys. 3: 379-387, 1981.
11. Hayes, K., C. P. Yardley, and L. C. Weaver. Evidence for descending tonic inhibition specifically affecting sympathetic pathways to the kidney in rats. J. Physiol. Lond. 434: 295-306, 1991.
12. Koizumi, K., and C. M. Brooks. The integration of autonomic system reactions: a discussion of autonomic reflexes, their control and their association with somatic reflexes. In: Reviews of Physiology: Biochemistry and Experimental Pharmacology, edited by R. H. Adrian, E. Helmrich, H. Holzer, R. Jung, K. Kramer, O. Krayer, F. Lynen, P. A. Miescher, H. Rasmussen, A. E. Renold, M. Trendelenberg, K. Ulrich, W. Vogt, and A. Weber. Berlin: Springer-Verlag, 1972, p. 1-68.
13. Krassioukov, A. V., A. W. Gelb, and L. C. Weaver. Action of propofol on central sympathetic mechanisms controlling blood pressure. Can. J. Anaesth. 40: 761-769, 1993.
14. Krassioukov, A. V., and L. C. Weaver. Episodic hypertension due to autonomic dysreflexia in acute and chronic spinal cord-injured rats. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H2077-H2083, 1995.
15. Krassioukov, A. V., and L. C. Weaver. Morphological changes in sympathetic preganglionic neurons after spinal cord injury in rats. Neuroscience 70: 211-226, 1996.
16. Lindan, R., E. Joiner, A. A. Freehafer, and C. Hazel. Incidence and clinical features of autonomic dysreflexia in patients with spinal cord injury. Paraplegia 18: 285-292, 1980.
17. Llewellyn-Smith, I. J., A. K. Cassam, N. R. Krenz, A. V. Krassioukov, J. B. Minson, P. M. Pilowsky, F. Arnolda, J. P. Chalmers, and L. C. Weaver. Autonomic dysreflexia: is reorganization of synapses on sympathetic preganglionic neurons to blame? In: Frontiers of Spinal Cord Research. Melbourne: Australian Spinal Cord Research Trust, 1996.
18. Mathias, C. J., and H. L. Frankel. The cardiovascular system in tetraplegia and paraplegia. In: Handbook of Clinical Neurology, edited by H. L. Frankel. Amsterdam: Elsevier Science Publishers, 1992, p. 435-456.
19. McKenna, K. E., and L. P. Schramm. Sympathetic preganglionic neurons in the isolated spinal cord of the neonatal rat. Brain Res. 269: 201-210, 1983.
20. Meckler, R. L., and L. C. Weaver. Splenic, renal, and cardiac nerves have unequal dependence upon tonic supraspinal inputs. Brain Res. 338: 123-135, 1985.
21. Muller, U. W., K. Dembowsky, J. Czachurski, and H. Seller. Tonic descending inhibition of the spinal cardio-sympathetic reflex in the cat. J. Auton. Nerv. Sys. 23: 111-123, 1988.
22. Naftchi, N. E. Mechanism of autonomic dysreflexia: contributions of catecholamine and peptide neurotransmitters. Ann. New York Acad. Sci. 579: 133-148, 1990.
23. Osborn, J. W., R. F. Taylor, and L. P. Schramm. Determinants of arterial pressure after chronic spinal transection in rats. Am. J. Physiol. 256 (Regulatory Integrative Comp. Physiol. 25): R666-R673, 1989.
24. Osborn, J. W., R. F. Taylor, and L. P. Schramm. Chronic cervical spinal cord injury and autonomic hyperreflexia in rats. Am. J. Physiol. 258 (Regulatory Integrative Comp. Physiol. 27): R169-R174, 1990.
25. Qu, L., R. Sherebrin, and L. C. Weaver. Blockade of spinal pathways decreases pre- and postganglionic discharge differentially. Am. J. Physiol. 255 (Regulatory Integrative Comp. Physiol. 24): R946-R951, 1988.
26. Sokol, R. R., and F. J. Rohlf. Biometry: The Principles and Practice of Statistics in Biological Research. San Francisco, CA: Freeman, 1981.
27. Stjernberg, L., H. Blumberg, and B. G. Wallin. Sympathetic activity in man after spinal cord injury. Outflow to muscle below the lesion. Brain 109: 695-715, 1986.
28. Taylor, R. B., and L. C. Weaver. Dorsal root afferent influences on tonic firing of renal and mesenteric sympathetic nerves in rats. Am. J. Physiol. 264 (Regulatory Integrative Comp. Physiol. 33): R1193-R1199, 1993.
29. Taylor, R. F., and L. P. Schramm. Differential effects of spinal transection on sympathetic nerve activities in rats. Am. J. Physiol. 253 (Regulatory Integrative Comp. Physiol. 22): R611-R618, 1987.
30. Trostel, K. A., and J. W. Osborn. Does the spinal cord generate functionally significant sympathetic activity in the awake rat? Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R1102-R1110, 1994.
31. Wallin, B. G., and L. Stjernberg. Sympathetic activity in man after spinal cord injury. Brain 107: 183-198, 1984.
32. Weaver, L. C., and R. D. Stein. Effects of spinal cord transection on sympathetic discharge in decerebrate-unanesthetized cats. Am. J. Physiol. 257 (Regulatory Integrative Comp. Physiol. 26): R1506-R1511, 1989.
33. Yoshimura, M., C. Polosa, and S. Nishi. Noradrenaline induces rhythmic bursting in sympathetic preganglionic neurons. Brain Res. 420: 147-151, 1987.