-
1
-
-
58849149001
-
The principles of human experimental technique (1959). Universities Federation for Animal Welfare (UFAW)
-
special edition, 238 p
-
Russel WMS, Burch RL. The principles of human experimental technique (1959). Universities Federation for Animal Welfare (UFAW). Herts, UK : Potters Bar, 1992 (special edition) : 238 p.
-
(1992)
Herts, UK : Potters Bar
-
-
Russel, W.M.S.1
Burch, R.L.2
-
2
-
-
0032619762
-
Knowledge-based expert systems for toxicity and metabolism prediction: DEREK, StAR and METEOR
-
Greene N, Judson PN, Langowski JJ, Marchant CA. Knowledge-based expert systems for toxicity and metabolism prediction: DEREK, StAR and METEOR. SAR QSAR Environ Res 1999 ; 10 : 299-314.
-
(1999)
SAR QSAR Environ Res
, vol.10
, pp. 299-314
-
-
Greene, N.1
Judson, P.N.2
Langowski, J.J.3
Marchant, C.A.4
-
3
-
-
0032609573
-
Development, characterization and application of predictive-toxicology models
-
Rosenkranz HS, Cunningham AR, Zhang YP, et al. Development, characterization and application of predictive-toxicology models. SAR QSAR Environ Res 1999 ; 10 : 277-98.
-
(1999)
SAR QSAR Environ Res
, vol.10
, pp. 277-298
-
-
Rosenkranz, H.S.1
Cunningham, A.R.2
Zhang, Y.P.3
-
4
-
-
28944443966
-
In silico assessment of chemical mutagenesis in comparison with results of Salmonella microsome assay on 909 chemicals
-
Hayashi M, Kamata E, Hirose A, et al. In silico assessment of chemical mutagenesis in comparison with results of Salmonella microsome assay on 909 chemicals. Mutat Res 2005 ; 588 : 129-35.
-
(2005)
Mutat Res
, vol.588
, pp. 129-135
-
-
Hayashi, M.1
Kamata, E.2
Hirose, A.3
-
5
-
-
33947417659
-
Integrating process safety with molecular modelling-based risk assessment of chemicals within REACH regulatory framework: Benefit and future challenges
-
Lewis A, Kazantis N, Fishtik I, et al. Integrating process safety with molecular modelling-based risk assessment of chemicals within REACH regulatory framework: benefit and future challenges. J Hasard Mat 2007 ; 142 : 592-602.
-
(2007)
J Hasard Mat
, vol.142
, pp. 592-602
-
-
Lewis, A.1
Kazantis, N.2
Fishtik, I.3
-
6
-
-
0033771951
-
Concordance of the toxicity of pharmaceuticals in humans and in animals
-
Olson H, Betton G, Robinson D, et al. Concordance of the toxicity of pharmaceuticals in humans and in animals. Regul Toxicol Pharmacol 2000 ; 32 : 56-67.
-
(2000)
Regul Toxicol Pharmacol
, vol.32
, pp. 56-67
-
-
Olson, H.1
Betton, G.2
Robinson, D.3
-
7
-
-
0031832805
-
Liver cell models in in vitro toxicology
-
Guillouzo A. Liver cell models in in vitro toxicology. Environ Health Perspect 1998 ; 106 (suppl 2) : 511-32.
-
(1998)
Environ Health Perspect
, vol.106
, Issue.SUPPL. 2
, pp. 511-532
-
-
Guillouzo, A.1
-
8
-
-
33847018050
-
-
Hewitt NJ, Lechón MJ, Houston JB, et al. Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies. Drug Metab Rev 2007 ; 39 : 159-234.
-
Hewitt NJ, Lechón MJ, Houston JB, et al. Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies. Drug Metab Rev 2007 ; 39 : 159-234.
-
-
-
-
9
-
-
34547162587
-
Concise review: No breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold!
-
Mannello F, Tonti GA. Concise review: no breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold! Stem Cells 2007 ; 25 : 1603-9.
-
(2007)
Stem Cells
, vol.25
, pp. 1603-1609
-
-
Mannello, F.1
Tonti, G.A.2
-
10
-
-
0037180522
-
Infection of a human hepatoma cell line by hepatitis b virus
-
Gripon P, Rumin S, Urban S, et al. Infection of a human hepatoma cell line by hepatitis b virus. Proc Natl Acad Sci USA 2002 ; 99 : 15655-60.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15655-15660
-
-
Gripon, P.1
Rumin, S.2
Urban, S.3
-
11
-
-
34247351508
-
Transdifferentiation of hepatocyte-like cells from the human hepatoma heparg cell line through bipotent progenitor
-
Cerec V, Glaise D, Gamier D, et al. Transdifferentiation of hepatocyte-like cells from the human hepatoma heparg cell line through bipotent progenitor. Hepatology 2007 ; 45 : 957-67.
-
(2007)
Hepatology
, vol.45
, pp. 957-967
-
-
Cerec, V.1
Glaise, D.2
Gamier, D.3
-
12
-
-
29944444269
-
Expression of cytochromes p450, conjugating enzymes and nuclear receptors in human hepatoma heparg cells
-
Aninat C, Piton A, Glaise D, et al. Expression of cytochromes p450, conjugating enzymes and nuclear receptors in human hepatoma heparg cells. Drug Metab Dispos 2006 ; 34 : 75-83.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 75-83
-
-
Aninat, C.1
Piton, A.2
Glaise, D.3
-
13
-
-
44149105179
-
Long-term functional stability of human heparg hepatocytes and use for chronic toxicity and genotoxicity studies
-
Josse R, Aninat C, Glaise D, et al. Long-term functional stability of human heparg hepatocytes and use for chronic toxicity and genotoxicity studies. Drug Metab Dispos 2008 ; 36 : 1111-8.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 1111-1118
-
-
Josse, R.1
Aninat, C.2
Glaise, D.3
-
14
-
-
1542380037
-
Toxicogenomics in predictive toxicology in drug development
-
Suter L, Babiss LE, Wheeldon EB. Toxicogenomics in predictive toxicology in drug development. Chem Biol 2004 ; 11 ; 161-71.
-
(2004)
Chem Biol
, vol.11
, pp. 161-171
-
-
Suter, L.1
Babiss, L.E.2
Wheeldon, E.B.3
-
15
-
-
20544466649
-
-
Robertson DG. Metabonomics in toxicology: a review. Toxicol Sci 2005 ; 85 : 809-22.
-
Robertson DG. Metabonomics in toxicology: a review. Toxicol Sci 2005 ; 85 : 809-22.
-
-
-
-
16
-
-
0032694577
-
Metabonomics: Understanding the metabolic responses of living systems to pathophysiological stimuli via multovariate statistical analysis of biological NMR spectroscopic data
-
Nicholson JK, Lindon JC, Holmes E. Metabonomics: understanding the metabolic responses of living systems to pathophysiological stimuli via multovariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999 ; 29 : 1181-9.
-
(1999)
Xenobiotica
, vol.29
, pp. 1181-1189
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
17
-
-
24644447094
-
Drug-induced oxidative stress in rat liver from a toxicogenomic perspective
-
McMillian M, Nie A, Parker B, et al. Drug-induced oxidative stress in rat liver from a toxicogenomic perspective. Toxicol Appl Pharmacol 2005 ; 207 : 171-8.
-
(2005)
Toxicol Appl Pharmacol
, vol.207
, pp. 171-178
-
-
McMillian, M.1
Nie, A.2
Parker, B.3
-
18
-
-
40649086615
-
Validation of putative biomarkers of nephrotoxicity in rats
-
Wang EJ, Snyder RD, Fielden MR, et al. Validation of putative biomarkers of nephrotoxicity in rats. Toxicology 2008 ; 246 : 91-100.
-
(2008)
Toxicology
, vol.246
, pp. 91-100
-
-
Wang, E.J.1
Snyder, R.D.2
Fielden, M.R.3
-
19
-
-
37149025669
-
Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies
-
Ellinger-Ziegelbauer H, Gmuender H, Badenburg A, Ahr HJ. Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies. Mutat Res 2008 ; 637 : 23-39.
-
(2008)
Mutat Res
, vol.637
, pp. 23-39
-
-
Ellinger-Ziegelbauer, H.1
Gmuender, H.2
Badenburg, A.3
Ahr, H.J.4
-
20
-
-
18844458022
-
Use of two-dimensional gel electrophoresis in predictive toxicology: Identification of potential early protein bimarkers in chemically induced hepatocarcinogenesis
-
Fella K, Gluckmann M, Hellmann J, et al. Use of two-dimensional gel electrophoresis in predictive toxicology: Identification of potential early protein bimarkers in chemically induced hepatocarcinogenesis. Proteomics 2005 ; 5 : 1914-27.
-
(2005)
Proteomics
, vol.5
, pp. 1914-1927
-
-
Fella, K.1
Gluckmann, M.2
Hellmann, J.3
-
21
-
-
13644258653
-
A toxicogenomic approach to drug-induced phospholipidosis: Analysis of its induction mechanism and establishment of a novel in vitro screening system
-
Sawada H, Takami K, Asahi S. A toxicogenomic approach to drug-induced phospholipidosis: analysis of its induction mechanism and establishment of a novel in vitro screening system. Toxicol Sci 2005 ; 83 : 282-92.
-
(2005)
Toxicol Sci
, vol.83
, pp. 282-292
-
-
Sawada, H.1
Takami, K.2
Asahi, S.3
-
23
-
-
33748491517
-
The microarray quality control (MAQC) project shows inter and intraplatform reproducibility of gene expression measurements
-
MAQC Consortium
-
MAQC Consortium. The microarray quality control (MAQC) project shows inter and intraplatform reproducibility of gene expression measurements. Nat Biotechnol 2006 ; 24 : 1151-61.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1151-1161
-
-
|