-
1
-
-
0028276796
-
A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
-
Burton JD, Bamford RN, Peters C et al. A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells. Proc Natl Acad Sci U S A 1994 91 : 4935 9.
-
(1994)
Proc Natl Acad Sci U S a
, vol.91
, pp. 4935-9
-
-
Burton, J.D.1
Bamford, R.N.2
Peters, C.3
-
2
-
-
0028179054
-
Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor
-
Grabstein KH, Eisenman J, Shanebeck K et al. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 1994 264 : 965 8.
-
(1994)
Science
, vol.264
, pp. 965-8
-
-
Grabstein, K.H.1
Eisenman, J.2
Shanebeck, K.3
-
3
-
-
33746547247
-
The biology of interleukin-2 and interleukin-15: Implications for cancer therapy and vaccine design
-
Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol 2006 6 : 595 601.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 595-601
-
-
Waldmann, T.A.1
-
4
-
-
0035102242
-
Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: Implications for immunotherapy
-
Waldmann TA, Dubois S, Tagaya Y. Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy. Immunity 2001 14 : 105 10.
-
(2001)
Immunity
, vol.14
, pp. 105-10
-
-
Waldmann, T.A.1
Dubois, S.2
Tagaya, Y.3
-
5
-
-
33646186619
-
Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis
-
Ma A, Koka R, Burkett P. Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis. Annu Rev Immunol 2006 24 : 657 79.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 657-79
-
-
Ma, A.1
Koka, R.2
Burkett, P.3
-
6
-
-
0034610970
-
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice
-
Kennedy MK, Glaccum M, Brown SN et al. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J Exp Med 2000 191 : 771 80.
-
(2000)
J Exp Med
, vol.191
, pp. 771-80
-
-
Kennedy, M.K.1
Glaccum, M.2
Brown, S.N.3
-
7
-
-
0032076635
-
Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15
-
Zhang X, Sun S, Hwang I, Tough DF, Sprent J. Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity 1998 8 : 591 9.
-
(1998)
Immunity
, vol.8
, pp. 591-9
-
-
Zhang, X.1
Sun, S.2
Hwang, I.3
Tough, D.F.4
Sprent, J.5
-
8
-
-
0033562382
-
Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15
-
Musso T, Calosso L, Zucca M et al. Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15. Blood 1999 93 : 3531 9.
-
(1999)
Blood
, vol.93
, pp. 3531-9
-
-
Musso, T.1
Calosso, L.2
Zucca, M.3
-
9
-
-
0035138935
-
Dermal fibroblasts sustain proliferation of activated T cells via membrane-bound interleukin-15 upon long-term stimulation with tumor necrosis factor-alpha
-
Rappl G, Kapsokefalou A, Heuser C et al. Dermal fibroblasts sustain proliferation of activated T cells via membrane-bound interleukin-15 upon long-term stimulation with tumor necrosis factor-alpha. J Invest Dermatol 2001 116 : 102 9.
-
(2001)
J Invest Dermatol
, vol.116
, pp. 102-9
-
-
Rappl, G.1
Kapsokefalou, A.2
Heuser, C.3
-
10
-
-
9144269943
-
Follicular dendritic cells produce IL-15 that enhances germinal center B cell proliferation in membrane-bound form
-
Park CS, Yoon SO, Armitage RJ, Choi YS. Follicular dendritic cells produce IL-15 that enhances germinal center B cell proliferation in membrane-bound form. J Immunol 2004 173 : 6676 83.
-
(2004)
J Immunol
, vol.173
, pp. 6676-83
-
-
Park, C.S.1
Yoon, S.O.2
Armitage, R.J.3
Choi, Y.S.4
-
11
-
-
1642344614
-
Monocyte surface-bound IL-15 can function as an activating receptor and participate in reverse signaling
-
Neely GG, Epelman S, Ma LL et al. Monocyte surface-bound IL-15 can function as an activating receptor and participate in reverse signaling. J Immunol 2004 172 : 4225 34.
-
(2004)
J Immunol
, vol.172
, pp. 4225-34
-
-
Neely, G.G.1
Epelman, S.2
Ma, L.L.3
-
12
-
-
24744454147
-
Human T cells constitutively express IL-15 that promotes ex vivo T cell homeostatic proliferation through autocrine/juxtacrine loops
-
Miranda-Carus ME, Benito-Miguel M, Llamas MA, Balsa A, Martin-Mola E. Human T cells constitutively express IL-15 that promotes ex vivo T cell homeostatic proliferation through autocrine/juxtacrine loops. J Immunol 2005 175 : 3656 62.
-
(2005)
J Immunol
, vol.175
, pp. 3656-62
-
-
Miranda-Carus, M.E.1
Benito-Miguel, M.2
Llamas, M.A.3
Balsa, A.4
Martin-Mola, E.5
-
13
-
-
0028221433
-
Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15
-
Giri JG, Ahdieh M, Eisenman J et al. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J 1994 13 : 2822 30.
-
(1994)
EMBO J
, vol.13
, pp. 2822-30
-
-
Giri, J.G.1
Ahdieh, M.2
Eisenman, J.3
-
14
-
-
0029099146
-
Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor
-
Giri JG, Kumaki S, Ahdieh M et al. Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. EMBO J 1995 14 : 3654 63.
-
(1995)
EMBO J
, vol.14
, pp. 3654-63
-
-
Giri, J.G.1
Kumaki, S.2
Ahdieh, M.3
-
15
-
-
13344278015
-
Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes
-
Anderson DM, Kumaki S, Ahdieh M et al. Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes. J Biol Chem 1995 270 : 29862 9.
-
(1995)
J Biol Chem
, vol.270
, pp. 29862-9
-
-
Anderson, D.M.1
Kumaki, S.2
Ahdieh, M.3
-
17
-
-
33646580769
-
The structure of the interleukin-15 alpha receptor and its implications for ligand binding
-
Lorenzen I, Dingley AJ, Jacques Y, Grotzinger J. The structure of the interleukin-15 alpha receptor and its implications for ligand binding. J Biol Chem 2006 281 : 6642 7.
-
(2006)
J Biol Chem
, vol.281
, pp. 6642-7
-
-
Lorenzen, I.1
Dingley, A.J.2
Jacques, Y.3
Grotzinger, J.4
-
18
-
-
0035399559
-
The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo
-
Wei X, Orchardson M, Gracie JA et al. The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. J Immunol 2001 167 : 277 82.
-
(2001)
J Immunol
, vol.167
, pp. 277-82
-
-
Wei, X.1
Orchardson, M.2
Gracie, J.A.3
-
19
-
-
3242776039
-
Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist
-
Mortier E, Bernard J, Plet A, Jacques Y. Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist. J Immunol 2004 173 : 1681 8.
-
(2004)
J Immunol
, vol.173
, pp. 1681-8
-
-
Mortier, E.1
Bernard, J.2
Plet, A.3
Jacques, Y.4
-
20
-
-
33644975335
-
Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 × IL-15R alpha fusion proteins
-
Mortier E, Quemener A, Vusio P et al. Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 × IL-15R alpha fusion proteins. J Biol Chem 2006 281 : 1612 9.
-
(2006)
J Biol Chem
, vol.281
, pp. 1612-9
-
-
Mortier, E.1
Quemener, A.2
Vusio, P.3
-
21
-
-
34548125264
-
Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
-
Chirifu M, Hayashi C, Nakamura T et al. Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans. Nat Immunol 2007 8 : 1001 7.
-
(2007)
Nat Immunol
, vol.8
, pp. 1001-7
-
-
Chirifu, M.1
Hayashi, C.2
Nakamura, T.3
-
22
-
-
0036826914
-
IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells
-
Dubois S, Mariner J, Waldmann TA, Tagaya Y. IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells. Immunity 2002 17 : 537 47.
-
(2002)
Immunity
, vol.17
, pp. 537-47
-
-
Dubois, S.1
Mariner, J.2
Waldmann, T.A.3
Tagaya, Y.4
-
23
-
-
11244255868
-
Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance
-
Kobayashi H, Dubois S, Sato N et al. Role of trans-cellular IL-15 presentation in the activation of NK cell-mediated killing, which leads to enhanced tumor immunosurveillance. Blood 2005 105 : 721 7.
-
(2005)
Blood
, vol.105
, pp. 721-7
-
-
Kobayashi, H.1
Dubois, S.2
Sato, N.3
-
24
-
-
4744366188
-
Reverse signaling through membrane-bound interleukin-15
-
Budagian V, Bulanova E, Orinska Z et al. Reverse signaling through membrane-bound interleukin-15. J Biol Chem 2004 279 : 42192 201.
-
(2004)
J Biol Chem
, vol.279
, pp. 42192-201
-
-
Budagian, V.1
Bulanova, E.2
Orinska, Z.3
-
25
-
-
5444239242
-
Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis
-
Burkett PR, Koka R, Chien M, Chai S, Boone DL, Ma A. Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis. J Exp Med 2004 200 : 825 34.
-
(2004)
J Exp Med
, vol.200
, pp. 825-34
-
-
Burkett, P.R.1
Koka, R.2
Chien, M.3
Chai, S.4
Boone, D.L.5
Ma, A.6
-
26
-
-
0037447075
-
IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory
-
Burkett PR, Koka R, Chien M et al. IL-15R alpha expression on CD8+ T cells is dispensable for T cell memory. Proc Natl Acad Sci U S A 2003 100 : 4724 9.
-
(2003)
Proc Natl Acad Sci U S a
, vol.100
, pp. 4724-9
-
-
Burkett, P.R.1
Koka, R.2
Chien, M.3
-
27
-
-
1642581680
-
Transregulation of memory CD8 T-cell proliferation by IL-15Ralpha+ bone marrow-derived cells
-
Schluns KS, Klonowski KD, Lefrancois L. Transregulation of memory CD8 T-cell proliferation by IL-15Ralpha+ bone marrow-derived cells. Blood 2004 103 : 988 94.
-
(2004)
Blood
, vol.103
, pp. 988-94
-
-
Schluns, K.S.1
Klonowski, K.D.2
Lefrancois, L.3
-
28
-
-
0030639208
-
Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms
-
Onu A, Pohl T, Krause H, Bulfone-Paus S. Regulation of IL-15 secretion via the leader peptide of two IL-15 isoforms. J Immunol 1997 158 : 255 62.
-
(1997)
J Immunol
, vol.158
, pp. 255-62
-
-
Onu, A.1
Pohl, T.2
Krause, H.3
Bulfone-Paus, S.4
-
29
-
-
34347233859
-
Membrane-bound interleukin (IL)-15 on renal tumor cells rescues natural killer cells from IL-2 starvation-induced apoptosis
-
Wittnebel S, Da Rocha S, Giron-Michel J et al. Membrane-bound interleukin (IL)-15 on renal tumor cells rescues natural killer cells from IL-2 starvation-induced apoptosis. Cancer Res 2007 67 : 5594 9.
-
(2007)
Cancer Res
, vol.67
, pp. 5594-9
-
-
Wittnebel, S.1
Da Rocha, S.2
Giron-Michel, J.3
-
30
-
-
3142732829
-
IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: Effect of methotrexate
-
Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. J Immunol 2004 173 : 1463 76.
-
(2004)
J Immunol
, vol.173
, pp. 1463-76
-
-
Miranda-Carus, M.E.1
Balsa, A.2
Benito-Miguel, M.3
Perez De Ayala, C.4
Martin-Mola, E.5
-
31
-
-
0031042456
-
Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis
-
McInnes IB, Leung BP, Sturrock RD, Field M, Liew FY. Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. Nat Med 1997 3 : 189 95.
-
(1997)
Nat Med
, vol.3
, pp. 189-95
-
-
McInnes, I.B.1
Leung, B.P.2
Sturrock, R.D.3
Field, M.4
Liew, F.Y.5
-
32
-
-
0034869941
-
Serum interleukin-15 is elevated in systemic lupus erythematosus
-
Aringer M, Stummvoll GH, Steiner G et al. Serum interleukin-15 is elevated in systemic lupus erythematosus. Rheumatology (Oxford) 2001 40 : 876 81.
-
(2001)
Rheumatology (Oxford)
, vol.40
, pp. 876-81
-
-
Aringer, M.1
Stummvoll, G.H.2
Steiner, G.3
-
33
-
-
0036635843
-
Proinflammatory interferon-gamma - Inducing monokines (interleukin-12, interleukin-18, interleukin-15) - Serum profile in patients with systemic lupus erythematosus
-
Robak E, Robak T, Wozniacka A, Zak-Prelich M, Sysa-Jedrzejowska A, Stepien H. Proinflammatory interferon-gamma - inducing monokines (interleukin-12, interleukin-18, interleukin-15) - serum profile in patients with systemic lupus erythematosus. Eur Cytokine Netw 2002 13 : 364 8.
-
(2002)
Eur Cytokine Netw
, vol.13
, pp. 364-8
-
-
Robak, E.1
Robak, T.2
Wozniacka, A.3
Zak-Prelich, M.4
Sysa-Jedrzejowska, A.5
Stepien, H.6
-
35
-
-
0028990471
-
Inquiry into murine and human lupus
-
Klinman DM, Steinberg AD. Inquiry into murine and human lupus. Immunol Rev 1995 144 : 157 93.
-
(1995)
Immunol Rev
, vol.144
, pp. 157-93
-
-
Klinman, D.M.1
Steinberg, A.D.2
-
36
-
-
0018746027
-
Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes
-
Aotsuka S, Okawa M, Ikebe K, Yokohari R. Measurement of anti-double-stranded DNA antibodies in major immunoglobulin classes. J Immunol Methods 1979 28 : 149 62.
-
(1979)
J Immunol Methods
, vol.28
, pp. 149-62
-
-
Aotsuka, S.1
Okawa, M.2
Ikebe, K.3
Yokohari, R.4
-
37
-
-
0036436131
-
Interleukin-15 interactions with interleukin-15 receptor complexes: Characterization and species specificity
-
Eisenman J, Ahdieh M, Beers C et al. Interleukin-15 interactions with interleukin-15 receptor complexes: characterization and species specificity. Cytokine 2002 20 : 121 9.
-
(2002)
Cytokine
, vol.20
, pp. 121-9
-
-
Eisenman, J.1
Ahdieh, M.2
Beers, C.3
-
38
-
-
0032211699
-
IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation
-
Lodolce JP, Boone DL, Chai S et al. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 1998 9 : 669 76.
-
(1998)
Immunity
, vol.9
, pp. 669-76
-
-
Lodolce, J.P.1
Boone, D.L.2
Chai, S.3
-
39
-
-
0030762744
-
Interleukin-15 protects from lethal apoptosis in vivo
-
Bulfone-Paus S, Ungureanu D, Pohl T et al. Interleukin-15 protects from lethal apoptosis in vivo. Nat Med 1997 3 : 1124 8.
-
(1997)
Nat Med
, vol.3
, pp. 1124-8
-
-
Bulfone-Paus, S.1
Ungureanu, D.2
Pohl, T.3
-
40
-
-
33846277906
-
The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells
-
Sato N, Patel HJ, Waldmann TA, Tagaya Y. The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells. Proc Natl Acad Sci USA 2007 104 : 588 93.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 588-93
-
-
Sato, N.1
Patel, H.J.2
Waldmann, T.A.3
Tagaya, Y.4
-
41
-
-
34250325108
-
Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15
-
Bulanova E, Budagian V, Duitman E et al. Soluble Interleukin IL-15Ralpha is generated by alternative splicing or proteolytic cleavage and forms functional complexes with IL-15. J Biol Chem 2007 282 : 13167 79.
-
(2007)
J Biol Chem
, vol.282
, pp. 13167-79
-
-
Bulanova, E.1
Budagian, V.2
Duitman, E.3
-
42
-
-
0034665543
-
Selective blockade of IL-15 by soluble IL-15 receptor alpha-chain enhances cardiac allograft survival
-
Smith XG, Bolton EM, Ruchatz H, Wei X, Liew FY, Bradley JA. Selective blockade of IL-15 by soluble IL-15 receptor alpha-chain enhances cardiac allograft survival. J Immunol 2000 165 : 3444 50.
-
(2000)
J Immunol
, vol.165
, pp. 3444-50
-
-
Smith, X.G.1
Bolton, E.M.2
Ruchatz, H.3
Wei, X.4
Liew, F.Y.5
Bradley, J.A.6
-
43
-
-
0032103993
-
Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: A role for IL-15 in development of antigen-induced immunopathology
-
Ruchatz H, Leung BP, Wei XQ, McInnes IB, Liew FY. Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology. J Immunol 1998 160 : 5654 60.
-
(1998)
J Immunol
, vol.160
, pp. 5654-60
-
-
Ruchatz, H.1
Leung, B.P.2
Wei, X.Q.3
McInnes, I.B.4
Liew, F.Y.5
|