메뉴 건너뛰기




Volumn 32, Issue 1, 2009, Pages 1-6

The physiopathology of the catastrophic antiphospholipid (Asherson's) syndrome: Compelling evidence

Author keywords

Antiphospholipid antibodies; Catastrophic antiphospholipid syndrome; DIC; HIT; Infection; Microthromboses; Molecular mimicry; SIRS; TTP

Indexed keywords

CROSS REACTING ANTIBODY;

EID: 58849102082     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2008.10.003     Document Type: Review
Times cited : (62)

References (60)
  • 1
    • 0026537186 scopus 로고
    • The catastrophic antiphospholipid syndrome
    • Asherson R.A. The catastrophic antiphospholipid syndrome. J Rheumatol 19 (1992) 508-512
    • (1992) J Rheumatol , vol.19 , pp. 508-512
    • Asherson, R.A.1
  • 3
    • 0031787008 scopus 로고    scopus 로고
    • The catastrophic antiphospholipid syndrome, 1998. A review of the clinical features, possible pathogenesis and treatment
    • Asherson R.A. The catastrophic antiphospholipid syndrome, 1998. A review of the clinical features, possible pathogenesis and treatment. Lupus 7 (1998) S55-S62
    • (1998) Lupus , vol.7
    • Asherson, R.A.1
  • 4
    • 0038376616 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines
    • Asherson R.A., Cervera R., de Groot P.G., Erkan D., Boffa M.C., Piette J.C., et al. Catastrophic antiphospholipid syndrome: international consensus statement on classification criteria and treatment guidelines. Lupus 12 (2003) 530-534
    • (2003) Lupus , vol.12 , pp. 530-534
    • Asherson, R.A.1    Cervera, R.2    de Groot, P.G.3    Erkan, D.4    Boffa, M.C.5    Piette, J.C.6
  • 5
    • 50949114768 scopus 로고    scopus 로고
    • Predictive, protective, orphan autoantibodies: the example of anti-phospholipid antibodies
    • Meroni P.L., and Shoenfeld Y. Predictive, protective, orphan autoantibodies: the example of anti-phospholipid antibodies. Autoimmun Rev 7 (2008) 585-587
    • (2008) Autoimmun Rev , vol.7 , pp. 585-587
    • Meroni, P.L.1    Shoenfeld, Y.2
  • 7
    • 0033958261 scopus 로고    scopus 로고
    • The role of infection in the pathogenesis of catastrophic antiphospholipid syndrome. Molecular mimicry?
    • Asherson R.A., and Shoenfeld Y. The role of infection in the pathogenesis of catastrophic antiphospholipid syndrome. Molecular mimicry?. J Rheumatol 27 (2000) 12-14
    • (2000) J Rheumatol , vol.27 , pp. 12-14
    • Asherson, R.A.1    Shoenfeld, Y.2
  • 8
    • 34247577467 scopus 로고    scopus 로고
    • Antiphospholipid antibodies: lessons from the bench
    • Koike T., Bohgaki M., Amengual O., and Atsumi T. Antiphospholipid antibodies: lessons from the bench. J Autoimmun 28 (2007) 129-133
    • (2007) J Autoimmun , vol.28 , pp. 129-133
    • Koike, T.1    Bohgaki, M.2    Amengual, O.3    Atsumi, T.4
  • 9
    • 38049064823 scopus 로고    scopus 로고
    • Pathogenesis of the antiphospholipid syndrome: an additional example of the mosaic of autoimmunity
    • Meroni P.L. Pathogenesis of the antiphospholipid syndrome: an additional example of the mosaic of autoimmunity. J Autoimmun 30 (2008) 99-103
    • (2008) J Autoimmun , vol.30 , pp. 99-103
    • Meroni, P.L.1
  • 10
    • 34548497139 scopus 로고    scopus 로고
    • Beta2-glycoprotein I and its clinical significance: from gene sequence to protein levels
    • Sodin-Semrl S., and Rozman B. Beta2-glycoprotein I and its clinical significance: from gene sequence to protein levels. Autoimmun Rev 6 (2007) 547-552
    • (2007) Autoimmun Rev , vol.6 , pp. 547-552
    • Sodin-Semrl, S.1    Rozman, B.2
  • 11
    • 33751324826 scopus 로고    scopus 로고
    • Laboratory studies on pathophysiology of the catastrophic antiphospholipid syndrome
    • Espinosa G., Bucciarelli S., Cervera R., Gómez-Puerta J.A., and Font J. Laboratory studies on pathophysiology of the catastrophic antiphospholipid syndrome. Autoimmun Rev 6 (2006) 68-71
    • (2006) Autoimmun Rev , vol.6 , pp. 68-71
    • Espinosa, G.1    Bucciarelli, S.2    Cervera, R.3    Gómez-Puerta, J.A.4    Font, J.5
  • 12
    • 0031947185 scopus 로고    scopus 로고
    • Thrombotic storm: when thrombosis begets thrombosis
    • Kitchens C.S. Thrombotic storm: when thrombosis begets thrombosis. Am J Med 104 (1998) 381-385
    • (1998) Am J Med , vol.104 , pp. 381-385
    • Kitchens, C.S.1
  • 13
    • 0033826480 scopus 로고    scopus 로고
    • Endothelial activation by aPL: a potential pathogenetic mechanism for the clinical manifestations of the syndrome
    • Meroni P.L., Raschi E., Camera M., Testoni C., Nicoletti F., Tincani A., et al. Endothelial activation by aPL: a potential pathogenetic mechanism for the clinical manifestations of the syndrome. J Autoimmun 15 (2000) 237-240
    • (2000) J Autoimmun , vol.15 , pp. 237-240
    • Meroni, P.L.1    Raschi, E.2    Camera, M.3    Testoni, C.4    Nicoletti, F.5    Tincani, A.6
  • 14
    • 0037528699 scopus 로고    scopus 로고
    • Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies
    • Raschi E., Testoni C., Bosisio D., Borghi M.O., Koike T., Mantovani A., et al. Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies. Blood 101 (2003) 3495-3500
    • (2003) Blood , vol.101 , pp. 3495-3500
    • Raschi, E.1    Testoni, C.2    Bosisio, D.3    Borghi, M.O.4    Koike, T.5    Mantovani, A.6
  • 15
    • 34250734572 scopus 로고    scopus 로고
    • Mechanisms of aPL-mediated thrombosis: effects of aPL on endothelium and platelets
    • Vega-Ostertag M.E., and Pierangeli S.S. Mechanisms of aPL-mediated thrombosis: effects of aPL on endothelium and platelets. Curr Rheumatol Rep 9 (2007) 190-197
    • (2007) Curr Rheumatol Rep , vol.9 , pp. 190-197
    • Vega-Ostertag, M.E.1    Pierangeli, S.S.2
  • 16
    • 0031761527 scopus 로고    scopus 로고
    • Origin of antiphospholipid antibodies: induction of aPL by viral peptides
    • Gharavi A.E., and Pierangeli S.S. Origin of antiphospholipid antibodies: induction of aPL by viral peptides. Lupus 7 (1998) S52-S54
    • (1998) Lupus , vol.7
    • Gharavi, A.E.1    Pierangeli, S.S.2
  • 17
    • 34247571341 scopus 로고    scopus 로고
    • Complement activation in anti-phospholipid syndrome: a clue for an inflammatory process?
    • Cavazzana I., Manuela N., Irene C., Barbara A., Sara S., Orietta B.M., et al. Complement activation in anti-phospholipid syndrome: a clue for an inflammatory process?. J Autoimmun 28 (2007) 160-164
    • (2007) J Autoimmun , vol.28 , pp. 160-164
    • Cavazzana, I.1    Manuela, N.2    Irene, C.3    Barbara, A.4    Sara, S.5    Orietta, B.M.6
  • 18
    • 0032847566 scopus 로고    scopus 로고
    • Induction of antiphospholipid antibodies by immunization with synthetic viral and bacterial peptides
    • Gharavi E.E., Chaimovich H., Cucurull E., Celli C.M., Tang H., Wilson W.A., et al. Induction of antiphospholipid antibodies by immunization with synthetic viral and bacterial peptides. Lupus 8 (1999) 449-455
    • (1999) Lupus , vol.8 , pp. 449-455
    • Gharavi, E.E.1    Chaimovich, H.2    Cucurull, E.3    Celli, C.M.4    Tang, H.5    Wilson, W.A.6
  • 19
    • 34548543161 scopus 로고    scopus 로고
    • Intracellular trafficking of beta2-glycoprotein I complexes with lipid vesicles in macrophages: implications on the development of antiphospholipid syndrome
    • Kajiwara T., Yasuda T., and Matsuura E. Intracellular trafficking of beta2-glycoprotein I complexes with lipid vesicles in macrophages: implications on the development of antiphospholipid syndrome. J Autoimmun 29 (2007) 164-173
    • (2007) J Autoimmun , vol.29 , pp. 164-173
    • Kajiwara, T.1    Yasuda, T.2    Matsuura, E.3
  • 20
    • 36649015106 scopus 로고    scopus 로고
    • Antiphospholipid syndrome (APS): where does it come from?
    • Sherer Y., Blank M., and Shoenfeld Y. Antiphospholipid syndrome (APS): where does it come from?. Best Pract Res Clin Rheumatol 21 (2007) 1071-1078
    • (2007) Best Pract Res Clin Rheumatol , vol.21 , pp. 1071-1078
    • Sherer, Y.1    Blank, M.2    Shoenfeld, Y.3
  • 21
    • 0036847630 scopus 로고    scopus 로고
    • NFkappaB is an essential intermediate in the activation of endothelial cells by anti-beta(2)-glycoprotein 1 antibodies
    • Dunoyer-Geindre S., de Moerloose P., Galve-de Rochemonteix B., Reber G., and Kruithof E.K. NFkappaB is an essential intermediate in the activation of endothelial cells by anti-beta(2)-glycoprotein 1 antibodies. Thromb Haemost 88 (2002) 851-857
    • (2002) Thromb Haemost , vol.88 , pp. 851-857
    • Dunoyer-Geindre, S.1    de Moerloose, P.2    Galve-de Rochemonteix, B.3    Reber, G.4    Kruithof, E.K.5
  • 22
    • 0025650954 scopus 로고
    • Increased thromboxane formation in patients with antiphospholipid syndrome
    • Arfors L., Vesterqvist O., Johnsson H., and Gréen K. Increased thromboxane formation in patients with antiphospholipid syndrome. Eur J Clin Invest 20 (1990) 607-612
    • (1990) Eur J Clin Invest , vol.20 , pp. 607-612
    • Arfors, L.1    Vesterqvist, O.2    Johnsson, H.3    Gréen, K.4
  • 23
    • 0030897237 scopus 로고    scopus 로고
    • Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation
    • Del Papa N., Guidali L., Sala A., Buccellati C., Khamashta M.A., Ichikawa K., et al. Endothelial cells as target for antiphospholipid antibodies. Human polyclonal and monoclonal anti-beta 2-glycoprotein I antibodies react in vitro with endothelial cells through adherent beta 2-glycoprotein I and induce endothelial activation. Arthritis Rheum 40 (1997) 551-561
    • (1997) Arthritis Rheum , vol.40 , pp. 551-561
    • Del Papa, N.1    Guidali, L.2    Sala, A.3    Buccellati, C.4    Khamashta, M.A.5    Ichikawa, K.6
  • 24
    • 85047700006 scopus 로고    scopus 로고
    • Role of anti-beta2 glycoprotein I antibodies in antiphospholipid syndrome: in vitro and in vivo studies
    • Meroni P.L., Ronda N., De Angelis V., Grossi C., Raschi E., and Borghi M.O. Role of anti-beta2 glycoprotein I antibodies in antiphospholipid syndrome: in vitro and in vivo studies. Clin Rev Allergy Immunol 32 (2007) 67-74
    • (2007) Clin Rev Allergy Immunol , vol.32 , pp. 67-74
    • Meroni, P.L.1    Ronda, N.2    De Angelis, V.3    Grossi, C.4    Raschi, E.5    Borghi, M.O.6
  • 26
    • 46049120813 scopus 로고    scopus 로고
    • Toll-like receptors, transduction-effector pathways, and disease diversity: evidence of an immunobiological paradigm explaining all human illness?
    • Atkinson T.J. Toll-like receptors, transduction-effector pathways, and disease diversity: evidence of an immunobiological paradigm explaining all human illness?. Int Rev Immunol 27 (2008) 255-281
    • (2008) Int Rev Immunol , vol.27 , pp. 255-281
    • Atkinson, T.J.1
  • 27
    • 0036169798 scopus 로고    scopus 로고
    • Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo
    • Gharavi A.E., Pierangeli S.S., Espinola R.G., Liu X., Colden-Stanfield M., and Harris E.N. Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo. Arthritis Rheum 46 (2002) 545-552
    • (2002) Arthritis Rheum , vol.46 , pp. 545-552
    • Gharavi, A.E.1    Pierangeli, S.S.2    Espinola, R.G.3    Liu, X.4    Colden-Stanfield, M.5    Harris, E.N.6
  • 28
    • 0035673283 scopus 로고    scopus 로고
    • Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: effect on the proadhesive and proinflammatory phenotype
    • Meroni P.L., Raschi E., Testoni C., Tincani A., Balestrieri G., Molteni R., et al. Statins prevent endothelial cell activation induced by antiphospholipid (anti-beta2-glycoprotein I) antibodies: effect on the proadhesive and proinflammatory phenotype. Arthritis Rheum 44 (2001) 2870-2878
    • (2001) Arthritis Rheum , vol.44 , pp. 2870-2878
    • Meroni, P.L.1    Raschi, E.2    Testoni, C.3    Tincani, A.4    Balestrieri, G.5    Molteni, R.6
  • 29
    • 0030589375 scopus 로고    scopus 로고
    • The anti-beta2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species' evolution
    • Tincani A., Spatola L., Prati E., Allegri F., Ferremi P., Cattaneo R., et al. The anti-beta2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species' evolution. J Immunol 157 (1996) 5732-5738
    • (1996) J Immunol , vol.157 , pp. 5732-5738
    • Tincani, A.1    Spatola, L.2    Prati, E.3    Allegri, F.4    Ferremi, P.5    Cattaneo, R.6
  • 31
    • 39649089396 scopus 로고    scopus 로고
    • Antiphospholipid antibodies, antiphospholipid syndrome and infections
    • Sène D., Piette J.C., and Cacoub P. Antiphospholipid antibodies, antiphospholipid syndrome and infections. Autoimmun Rev 7 (2008) 272-277
    • (2008) Autoimmun Rev , vol.7 , pp. 272-277
    • Sène, D.1    Piette, J.C.2    Cacoub, P.3
  • 32
    • 37649022042 scopus 로고    scopus 로고
    • Lessons from the "Euro-Phospholipid" project
    • Cervera R. Lessons from the "Euro-Phospholipid" project. Autoimmun Rev 7 (2008) 174-178
    • (2008) Autoimmun Rev , vol.7 , pp. 174-178
    • Cervera, R.1
  • 34
    • 0033197971 scopus 로고    scopus 로고
    • GDKV-induced antiphospholipid antibodies enhance thrombosis and activate endothelial cells in vivo and in vitro
    • Gharavi A.E., Pierangeli S.S., Colden-Stanfield M., Liu X.W., Espinola R.G., and Harris E.N. GDKV-induced antiphospholipid antibodies enhance thrombosis and activate endothelial cells in vivo and in vitro. J Immunol 163 (1999) 2922-2927
    • (1999) J Immunol , vol.163 , pp. 2922-2927
    • Gharavi, A.E.1    Pierangeli, S.S.2    Colden-Stanfield, M.3    Liu, X.W.4    Espinola, R.G.5    Harris, E.N.6
  • 35
    • 28044458991 scopus 로고    scopus 로고
    • Multiorgan failure and antiphospholipid antibodies: the catastrophic antiphospholipid (Asherson's) syndrome
    • Asherson R.A. Multiorgan failure and antiphospholipid antibodies: the catastrophic antiphospholipid (Asherson's) syndrome. Immunobiology 210 (2005) 727-733
    • (2005) Immunobiology , vol.210 , pp. 727-733
    • Asherson, R.A.1
  • 36
    • 34248656968 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome and sepsis. A common link?
    • Espinosa G., Cervera R., and Asherson R.A. Catastrophic antiphospholipid syndrome and sepsis. A common link?. J Rheumatol 34 (2007) 923-926
    • (2007) J Rheumatol , vol.34 , pp. 923-926
    • Espinosa, G.1    Cervera, R.2    Asherson, R.A.3
  • 37
    • 42149093162 scopus 로고    scopus 로고
    • Endothelial cell activation by immunoglobulins from patients with immune thrombocytopenic purpura or with antiphospholipid syndrome
    • Dunoyer-Geindre S., Boehlen F., Favier R., Wahl D., Musial J., Korte W., et al. Endothelial cell activation by immunoglobulins from patients with immune thrombocytopenic purpura or with antiphospholipid syndrome. Haematologica 93 (2008) 635-636
    • (2008) Haematologica , vol.93 , pp. 635-636
    • Dunoyer-Geindre, S.1    Boehlen, F.2    Favier, R.3    Wahl, D.4    Musial, J.5    Korte, W.6
  • 38
    • 0035793334 scopus 로고    scopus 로고
    • Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin
    • Pierangeli S.S., Espinola R.G., Liu X., and Harris E.N. Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin. Circ Res 88 (2001) 245-250
    • (2001) Circ Res , vol.88 , pp. 245-250
    • Pierangeli, S.S.1    Espinola, R.G.2    Liu, X.3    Harris, E.N.4
  • 39
    • 34948874137 scopus 로고    scopus 로고
    • Peripheral vascular occlusions leading to gangrene and amputations in antiphospholipid antibody positive patients
    • Asherson R.A., Cervera R., and Shoenfeld Y. Peripheral vascular occlusions leading to gangrene and amputations in antiphospholipid antibody positive patients. Ann N Y Acad Sci 1108 (2007) 515-529
    • (2007) Ann N Y Acad Sci , vol.1108 , pp. 515-529
    • Asherson, R.A.1    Cervera, R.2    Shoenfeld, Y.3
  • 40
    • 34547218488 scopus 로고    scopus 로고
    • Anti-beta2GPI-antibody-induced endothelial cell gene expression profiling reveals induction of novel pro-inflammatory genes potentially involved in primary antiphospholipid syndrome
    • Hamid C., Norgate K., D'Cruz D.P., Khamashta M.A., Arno M., Pearson J.D., et al. Anti-beta2GPI-antibody-induced endothelial cell gene expression profiling reveals induction of novel pro-inflammatory genes potentially involved in primary antiphospholipid syndrome. Ann Rheum Dis 66 (2007) 1000-1007
    • (2007) Ann Rheum Dis , vol.66 , pp. 1000-1007
    • Hamid, C.1    Norgate, K.2    D'Cruz, D.P.3    Khamashta, M.A.4    Arno, M.5    Pearson, J.D.6
  • 41
    • 33746993589 scopus 로고    scopus 로고
    • Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors in a series of 250 patients
    • Bucciarelli S., Espinosa G., Cervera R., Erkan D., Gómez-Puerta J.A., Ramos-Casals M., et al. Mortality in the catastrophic antiphospholipid syndrome: causes of death and prognostic factors in a series of 250 patients. Arthritis Rheum 54 (2006) 2568-2576
    • (2006) Arthritis Rheum , vol.54 , pp. 2568-2576
    • Bucciarelli, S.1    Espinosa, G.2    Cervera, R.3    Erkan, D.4    Gómez-Puerta, J.A.5    Ramos-Casals, M.6
  • 42
    • 41149125428 scopus 로고    scopus 로고
    • Pathogenesis, diagnosis, and management of disseminated intravascular coagulation: a literature review
    • Dalainas I. Pathogenesis, diagnosis, and management of disseminated intravascular coagulation: a literature review. Eur Rev Med Pharmacol Sci 12 (2008) 19-31
    • (2008) Eur Rev Med Pharmacol Sci , vol.12 , pp. 19-31
    • Dalainas, I.1
  • 43
    • 0033370808 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation. Clinical and physiopathological mechanisms and manifestations
    • Bick R.L., Arun B., and Frenkel E.P. Disseminated intravascular coagulation. Clinical and physiopathological mechanisms and manifestations. Haemostasis 29 (1999) 111-134
    • (1999) Haemostasis , vol.29 , pp. 111-134
    • Bick, R.L.1    Arun, B.2    Frenkel, E.P.3
  • 44
    • 33751322492 scopus 로고    scopus 로고
    • Pregnancy and puerperium are high susceptibility periods for the development of catastrophic antiphospholipid syndrome
    • Gómez-Puerta J.A., Cervera R., Espinosa G., Bucciarelli S., and Font J. Pregnancy and puerperium are high susceptibility periods for the development of catastrophic antiphospholipid syndrome. Autoimmun Rev 6 (2006) 85-88
    • (2006) Autoimmun Rev , vol.6 , pp. 85-88
    • Gómez-Puerta, J.A.1    Cervera, R.2    Espinosa, G.3    Bucciarelli, S.4    Font, J.5
  • 45
    • 33751336596 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid (Asherson's) syndrome and genetic thrombophilic disorders in obstetrics
    • Makatsariya A., Asherson R.A., Bitsadze V., Baimuradova S., and Akinshina S. Catastrophic antiphospholipid (Asherson's) syndrome and genetic thrombophilic disorders in obstetrics. Autoimmun Rev 6 (2006) 89-93
    • (2006) Autoimmun Rev , vol.6 , pp. 89-93
    • Makatsariya, A.1    Asherson, R.A.2    Bitsadze, V.3    Baimuradova, S.4    Akinshina, S.5
  • 47
    • 0028641308 scopus 로고
    • Lupus anticoagulant autoantibody induces apoptosis in umbilical vein endothelial cells: involvement of annexin V
    • Nakamura N., Shidara Y., Kawaguchi N., Azuma C., Mitsuda N., Onishi S., et al. Lupus anticoagulant autoantibody induces apoptosis in umbilical vein endothelial cells: involvement of annexin V. Biochem Biophys Res Commun 205 (1994) 1488-1493
    • (1994) Biochem Biophys Res Commun , vol.205 , pp. 1488-1493
    • Nakamura, N.1    Shidara, Y.2    Kawaguchi, N.3    Azuma, C.4    Mitsuda, N.5    Onishi, S.6
  • 48
    • 0031756049 scopus 로고    scopus 로고
    • Role of caspases 1 and 3 and Bcl-2-related molecules in endothelial cell apoptosis associated with thrombotic microangiopathies
    • Mitra D., Kim J., MacLow C., Karsan A., and Laurence J. Role of caspases 1 and 3 and Bcl-2-related molecules in endothelial cell apoptosis associated with thrombotic microangiopathies. Am J Hematol 59 (1998) 279-287
    • (1998) Am J Hematol , vol.59 , pp. 279-287
    • Mitra, D.1    Kim, J.2    MacLow, C.3    Karsan, A.4    Laurence, J.5
  • 49
    • 33748499609 scopus 로고    scopus 로고
    • Thrombotic microangiopathies: an update
    • Franchini M. Thrombotic microangiopathies: an update. Hematology 11 (2006) 139-146
    • (2006) Hematology , vol.11 , pp. 139-146
    • Franchini, M.1
  • 50
    • 34249806311 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases
    • Gómez-Puerta J.A., Cervera R., Espinosa G., Asherson R.A., García-Carrasco M., da Costa I.P., et al. Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases. Ann Rheum Dis 66 (2007) 740-746
    • (2007) Ann Rheum Dis , vol.66 , pp. 740-746
    • Gómez-Puerta, J.A.1    Cervera, R.2    Espinosa, G.3    Asherson, R.A.4    García-Carrasco, M.5    da Costa, I.P.6
  • 51
    • 27644434506 scopus 로고    scopus 로고
    • Thrombocytopenic conditions - autoimmunity and hypercoagulability: commonalities and differences in ITP, TTP, HIT, and APS
    • Kravitz M.S., and Shoenfeld Y. Thrombocytopenic conditions - autoimmunity and hypercoagulability: commonalities and differences in ITP, TTP, HIT, and APS. Am J Hematol 80 (2005) 232-242
    • (2005) Am J Hematol , vol.80 , pp. 232-242
    • Kravitz, M.S.1    Shoenfeld, Y.2
  • 52
    • 0030797843 scopus 로고    scopus 로고
    • Quantitation of platelet-specific autoantibodies in platelet eluates of ITP patients measured by a novel ELISA using the purified glycoprotein complexes GPIIb/IIIa and GPIb/IX as antigens
    • Hurlimann-Forster M., Steiner B., and von Felten A. Quantitation of platelet-specific autoantibodies in platelet eluates of ITP patients measured by a novel ELISA using the purified glycoprotein complexes GPIIb/IIIa and GPIb/IX as antigens. Br J Haematol 98 (1997) 328-335
    • (1997) Br J Haematol , vol.98 , pp. 328-335
    • Hurlimann-Forster, M.1    Steiner, B.2    von Felten, A.3
  • 53
    • 0033824676 scopus 로고    scopus 로고
    • Pathophysiology of the catastrophic antiphospholipid syndrome (CAPS)
    • Triplett D.A., and Asherson R.A. Pathophysiology of the catastrophic antiphospholipid syndrome (CAPS). Am J Hematol 66 (2000) 154-159
    • (2000) Am J Hematol , vol.66 , pp. 154-159
    • Triplett, D.A.1    Asherson, R.A.2
  • 54
    • 0029975366 scopus 로고    scopus 로고
    • Thrombotic risk in hereditary antithrombin III, protein C, or protein S deficiency. A cooperative, retrospective study. Gesellschaft fur Thrombose- und Hamostaseforschung (GTH) Study Group on Natural Inhibitors
    • Pabinger I., and Schneider B. Thrombotic risk in hereditary antithrombin III, protein C, or protein S deficiency. A cooperative, retrospective study. Gesellschaft fur Thrombose- und Hamostaseforschung (GTH) Study Group on Natural Inhibitors. Arterioscler Thromb Vasc Biol 16 (1996) 742-748
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 742-748
    • Pabinger, I.1    Schneider, B.2
  • 55
    • 16444373878 scopus 로고    scopus 로고
    • Catastrophic antiphospholipid syndrome: a rare cause of disseminated microvascular thrombotic injury - a case report with pathological and molecular correlative studies
    • Lai S., Walker D.H., and Elghetany M.T. Catastrophic antiphospholipid syndrome: a rare cause of disseminated microvascular thrombotic injury - a case report with pathological and molecular correlative studies. Pathol Int 55 (2005) 144-149
    • (2005) Pathol Int , vol.55 , pp. 144-149
    • Lai, S.1    Walker, D.H.2    Elghetany, M.T.3
  • 56
    • 12344312949 scopus 로고    scopus 로고
    • Significance of valine/leucine247 polymorphism of beta2-glycoprotein I in antiphospholipid syndrome: increased reactivity of anti-beta2-glycoprotein I autoantibodies to the valine247 beta2-glycoprotein I variant
    • Yasuda S., Atsumi T., Matsuura E., Kaihara K., Yamamoto D., Ichikawa K., et al. Significance of valine/leucine247 polymorphism of beta2-glycoprotein I in antiphospholipid syndrome: increased reactivity of anti-beta2-glycoprotein I autoantibodies to the valine247 beta2-glycoprotein I variant. Arthritis Rheum 52 (2005) 212-218
    • (2005) Arthritis Rheum , vol.52 , pp. 212-218
    • Yasuda, S.1    Atsumi, T.2    Matsuura, E.3    Kaihara, K.4    Yamamoto, D.5    Ichikawa, K.6
  • 57
    • 34547771658 scopus 로고    scopus 로고
    • The efficacy of specific IVIG anti-idiotypic antibodies in antiphospholipid syndrome (APS): trophoblast invasiveness and APS animal model
    • Blank M., Anafi L., Zandman-Goddard G., Krause I., Goldman S., Shalev E., et al. The efficacy of specific IVIG anti-idiotypic antibodies in antiphospholipid syndrome (APS): trophoblast invasiveness and APS animal model. Int Immunol 19 (2007) 857-865
    • (2007) Int Immunol , vol.19 , pp. 857-865
    • Blank, M.1    Anafi, L.2    Zandman-Goddard, G.3    Krause, I.4    Goldman, S.5    Shalev, E.6
  • 59
    • 34249292329 scopus 로고    scopus 로고
    • The management of the patient with unexpected autoantibody positivity
    • Bagnasco M., Grassia L., and Pesce G. The management of the patient with unexpected autoantibody positivity. Autoimmun Rev 6 (2007) 347-353
    • (2007) Autoimmun Rev , vol.6 , pp. 347-353
    • Bagnasco, M.1    Grassia, L.2    Pesce, G.3
  • 60
    • 51749095474 scopus 로고    scopus 로고
    • Cryptic natural autoantibodies and co-potentiators
    • Cheng H.M., and Chamley L. Cryptic natural autoantibodies and co-potentiators. Autoimmun Rev 7 (2008) 431-434
    • (2008) Autoimmun Rev , vol.7 , pp. 431-434
    • Cheng, H.M.1    Chamley, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.