The management of the patient with unexpected autoantibody positivity

Autoimmunity Reviews

Volumn 6, Issue 6, 2007, Pages 347-353

  Bagnasco, Marcello ^a   Grassia, Lidia ^a   Pesce, Giampaola ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

Anti nuclear antibodies; Anti phospholipid antibodies; Anti TPO antibodies; Autoantibodies; Autoimmune disease; Celiac disease

Indexed keywords

AMIODARONE; ANTICOAGULANT AGENT; ANTINUCLEAR ANTIBODY; AUTOANTIBODY; LITHIUM CARBONATE; PHOSPHOLIPID ANTIBODY; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; THYROID ANTIBODY;

ANTIBODY DETECTION; AUTOIMMUNE DISEASE; AUTOIMMUNE THYROIDITIS; CELIAC DISEASE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; GLUTEN FREE DIET; HUMAN; IMMUNOFLUORESCENCE TEST; MICROARRAY ANALYSIS; PATIENT CARE; PREVALENCE; REVIEW; STRATEGIC PLANNING; THROMBOSIS; TISSUE SECTION;

ANTIBODIES, ANTINUCLEAR; ANTIBODIES, ANTIPHOSPHOLIPID; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CELIAC DISEASE; DIAGNOSTIC ERRORS; HUMANS; IMMUNOLOGIC TESTS; PROTEIN ARRAY ANALYSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THYROIDITIS, AUTOIMMUNE;

EID: 34249292329     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2007.01.011     Document Type: Review

References (40)

1. Scofield R.H. Autoantibodies as predictors of disease. Lancet 8 363 (2004) 1544-1546
2. Venkatasubbarao S. Microarrays status and prospects. Trends Biotechnol 22 (2004) 630-637
3. Egner W. The use of laboratory tests in the diagnosis of SLE. J Clin Pathol 53 (2000) 424-432
4. Emlen W., and O'Neill L. Clinical significance of antinuclear antibodies: comparison of detection with immunofluorescence and enzyme-linked immunosorbent assays. Arthritis Rheum 40 (1997) 1612-1618
5. Tonutti E., Bassetti D., Piazza A., Visentini D., Poletto M., Bassetto F., et al. Diagnostic accuracy of ELISA methods as an alternative screening test to indirect immunofluorescence for the detection of antinuclear antibodies. Evaluation of five commercial kits. Autoimmunity 37 (2004) 171-176
6. Tan E.M., Feltkamp T.E., Smolen J.S., Butcher B., Dawkins R., Fritzler M.J., et al. Range of antinuclear antibodies in "healthy" individuals. Arthritis Rheum 40 (1997) 1601-1611
7. Bizzaro N., and Wiik A. Appropriateness in anti-nuclear antibody testing: from clinical request to strategic laboratory practice. Clin Exp Rheumatol 22 (2004) 349-355
8. Vaile J.H., Dyke L., Kherani R., Johnston C., Higgins T., and Russell A.S. Is high titre ANA specific for connective tissue disease?. Clin Exp Rheumatol 18 (2000) 433-438
9. Peene I., Meheus L., Veys E.M., and De Keyser F. Detection and identification of antinuclear antibodies (ANA) in a large and consecutive cohort of serum samples referred for ANA testing. Ann Rheum Dis 60 (2001) 1131-1136
10. Dawkins R.L., Martinez O.P., Freitas E.M., and Hollingsworth P.N. Diagnosis of autoimmune disease. In: Rose N.R., and Mackay I.R. (Eds). The autoimmune diseases. 3rd ed. (1998), Academic Press, San Diego 821-831
11. Vlachoyiannopoulos P.G., Tzavara V., Dafni U., Spanos E., and Moutsopoulos H.M. Clinical features and evolution of antinuclear antibody positive individuals in a rheumatology outpatient clinic. J Rheumatol 25 (1998) 886-891
12. Loviselli A., Velluzzi F., Mossa P., Cambosu M.A., Secci G., Atzeni F., et al. Sardinian Schoolchildren Study Group. The Sardinian Autoimmunity Study: 3. Studies on circulating antithyroid antibodies in Sardinian schoolchildren: relationship to goiter prevalence and thyroid function. Thyroid 11 (2001) 849-857
13. Vanderpump M.P.J., Tunbridge W.M.G., French J.M., Appleton D., Bates D., Clark F., et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol 43 (1995) 55-68
14. Baloch Z., Carayon P., Conte-Devolx B., Demers L.M., Feldt-Rasmussen U., Henry J.F., et al. Guidelines Committee, National Academy of Clinical Biochemistry. Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease. Thyroid 13 (2003) 3-126
15. Szyper-Kravitz M., Marai I., and Shoenfeld Y. Coexistence of thyroid autoimmunity with other autoimmune diseases: friend or foe? Additional aspects on the mosaic of autoimmunity. Autoimmunity 38 (2005) 247-255
16. Muller A.F., Drexhage H.A., and Berghout A. Postpartum thyroiditis and autoimmune thyroiditis in women of childbearing age: recent insights and consequences for antenatal and postnatal care. Endocr Rev 22 (2001) 605-630
17. Pedersen I.B., Laurberg P., Knudsen N., Jorgensen T., Perrild H., Ovesen L., et al. A population study of association between thyroid autoantibodies in serum and abnormalities in thyroid function and structure. Clin Endocrinol 62 (2005) 713-720
18. Villalta D., Orunesu E., Tozzoli R., Montagna P., Pesce G., Bizzaro N., et al. Analytical and diagnostic accuracy of "second generation" assays for thyrotrophin receptor antibodies with radioactive and chemiluminescent tracers. J Clin Pathol 57 (2004) 378-382
19. Cervera R., Piette J.C., Font J., Khamashta M.A., Shoenfeld Y., Camps M.T., et al. Euro-Phospholipid Project Group. Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1000 patients. Arthritis Rheum 46 (2002) 1019-1027
20. Uthman I., and Khamashta M. Ethnic and geographical variation in antiphospholipid (Hughes) syndrome. Ann Rheum Dis 64 (2005) 1671-1676
21. 2- glycoprotein 1, prothrombin, protein C, protein S, and annexin V in patients with systemic lupus erythematosus and thrombotic and thrombocytopenic complications. Clin Chem 47 (2001) 1008-1015
22. Bizzaro N., Tonutti E., Villalta D., Tampoia M., and Tozzoli R. Prevalence and clinical correlation of anti-phospholipid-binding protein antibodies in anticardiolipin-negative patients with systemic lupus erythematosus and women with unexplained recurrent miscarriages. Arch Pathol Lab Med 129 (2005) 61-68
23. Palosuo T., Virtamo J., Haukka J., Taylor P.R., Aho K., Puurunen M., et al. High antibody levels to prothrombin imply a risk of deep venous thrombosis and pulmonary embolism in middle-aged men. Thromb Haemost 78 (1997) 1178-1182
24. Lockshin M., Tenedios F., Petri M., McCarty G., Forastiero R., Krilis S., et al. Cardiac disease in the antiphospholipid syndrome: recommendations for treatment. Committee consensus report. Lupus 12 (2003) 518-523
25. Blank M., Cohen J., Toder V., and Shoenfeld Y. Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies. Proc Natl Acad Sci U S A 88 (1991) 3069-3073
26. Alarcon-Segovia D., Boffa M.C., Branch W., Cervera R., Gharavi A., Khamashta M., et al. Prophylaxis of the antiphospholipid syndrome: a consensus report. Lupus 12 (2003) 499-503
27. Matsuura E., Igarashi Y., Fujimoto M., Ichikawa K., Suzuki T., Sumida T., et al. Heterogeneity of anticardiolipin antibodies defined by the anticardiolipin cofactor. J Immunol 148 (1992) 3885-3891
28. Merkel P.A., Chang Y., Pierangeli S.S., Convery K., Harris E.N., and Polisson R.P. The prevalence and clinical associations of anticardiolipin antibodies in a large inception cohort of patients with connective tissue diseases. Am J Med 101 (1996) 576-583
29. Nardo S., Della Guardia M., Santaguida M.G., Virili C., Gargano L., and Centanni M. Recurrent pregnancy loss and thyroid disease: an underestimated aspect of autoimmune polyglandular syndrome. J Endocrinol Investig 28 (2005) 49
30. Rees J.D., Lanca S., Marques P.V., Gomez-Puerta J.A., Moco R., Oliveri C., et al. Prevalence of the antiphospholipid syndrome in primary systemic vasculitis. Ann Rheum Dis 65 (2006) 109-111
31. Lerner A., Kumar V., and Iancu T.C. Immunological diagnosis of childhood coeliac disease: comparison between antigliadin, antireticulin and antiendomysial antibodies. Clin Exp Immunol 95 (1994) 78-82
32. Bagnasco M., Montagna P., De Alessandri A., Castellano E., Pesce G.P., and Gatti R. IgA antiendomysium antibodies in human umbilical cord sections as a screening test in relatives of patients with celiac disease. Allergy 52 (1997) 1017-1021
33. Collin P., Kaukinen K., Vogelsang H., Korponay-Szabo I., Sommer R., Schreier E., et al. Antiendomysial and antihuman recombinant tissue transglutaminase antibodies in the diagnosis of coeliac disease: a biopsy-proven European multicentre study. Eur J Gastroenterol Hepatol 17 (2005) 85-91
34. Mäki M., Mustalahti K., Kokkonen J., Kulmala P., Haapalahti M., Karttunen T., et al. Prevalence of celiac disease among children in Finland. N Engl J Med 348 (2003) 2517-2524
35. Tommasini A., Not T., Kiren V., Baldas V., Santon D., Trevisiol C., et al. Mass screening for coeliac disease using antihuman transglutaminase antibody assay. Arch Dis Child 89 (2004) 512-515
36. Card T.R., West J., and Holmes G.K. Risk of malignancy in diagnosed coeliac disease: a 24-year prospective, population-based, cohort study. Aliment Pharmacol Ther 20 (2004) 769-775
37. Mearin L.M., Catassi C., Brousse N., Brand R., Collin P., Fabiani E., et al. On behalf of the Biomed Study Group on Coeliac Disease and non-Hodgkin Lymphoma. European multi-centre study on coeliac disease and non-Hodgkin lymphoma. Eur J Gastroenterol Hepatol 18 (2006) 187-194
38. Hill I.D., Dirks M.H., Liptak G.S., Colletti R.B., Fasano A., Guandalini S., et al. North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 40 (2005) 1-19
39. Tonutti E., Visentini D., Bizzaro N., Villalta D., Bagnasco M., Tozzoli R., et al. Guidelines for the serological and histopathological diagnosis of celiac disease. Int J Lab Med 2 (2005) 110-122
40. Shoenfeld Y., and Tincani A. Autoantibodies-the smoke and the fire. Autoimmunity 38 (2005) 1-2