Control of oxidative reactions of hemoglobin in the design of blood substitutes: Role of the ascorbate-glutathione antioxidant system

Artificial Organs

Volumn 33, Issue 2, 2009, Pages 115-126

  Simoni, Jan ^a   Villanueva Meyer, Javier ^a   Simoni, Grace ^a   Moeller, John F ^a   Wesson, Donald E ^b  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Ascorbate; Blood substitute; Glutathione; Hemoglobin; Oxidative reactions

Indexed keywords

ANTIOXIDANTS; BLOOD; DEGRADATION; FREE RADICAL REACTIONS; FREE RADICALS; GENE EXPRESSION; HEMOGLOBIN; HYDROGEN PEROXIDE; IONS; IRON COMPOUNDS; OXIDATION; PORPHYRINS; REACTION INTERMEDIATES; REDOX REACTIONS; SIGNAL TRANSDUCTION;

ANTIOXIDANT SYSTEMS; ASCORBATE; DEGRADATION PRODUCTS; DISMUTATION; FENTON REACTIONS; GLUTHATHIONE; HAEMOGLOBINS; HEME DEGRADATION; OXIDATIVE REACTION; SUPEROXIDE ANIONS;

PEPTIDES;

ANGIOTENSIN DERIVATIVE; ASCORBIC ACID; BLOOD SUBSTITUTE; CD163 ANTIGEN; FERROUS GLUCONATE; FERROUS HEMOGLOBIN; FERRYL HEMOGLOBIN; GLUTATHIONE; HAPTOGLOBIN; HEME; HEME OXYGENASE 1; HEMOGLOBIN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; ISOPROSTANE DERIVATIVE; METHEMOGLOBIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ERYTHROCYTE MEMBRANE; FENTON REACTION; GENE EXPRESSION; LIPID PEROXIDATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 58849097270     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2008.00695.x     Document Type: Article

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