Adenosine, oxidative stress and cytoprotection

Japanese Journal of Pharmacology

Volumn 86, Issue 3, 2001, Pages 265-274

  Ramkumar, V ^a   Hallam, D M ^a   Nie, Z ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine; Adenosine receptor; Cytoprotection; Nuclear factor kappa B; Oxidative stress

Indexed keywords

ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ALPHA INTERFERON; CISPLATIN; CYCLIC AMP; CYCLOHEXIMIDE; DACTINOMYCIN; DAUNORUBICIN; DOXORUBICIN; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOXANTRONE; NEUROTRANSMITTER; PROTEIN; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

BRADYCARDIA; CARDIOVASCULAR SYSTEM; CELL DAMAGE; CELL PROTECTION; CENTRAL NERVOUS SYSTEM; DEPHOSPHORYLATION; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; HEART INFARCTION PREVENTION; HEART PROTECTION; HUMAN; IMMUNOREGULATION; LIPOLYSIS; METABOLIC INHIBITION; METABOLIC REGULATION; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATIVE STRESS; PARACRINE SIGNALING; PHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; REPERFUSION; REVIEW; SEDATION; VASODILATATION;

EID: 0034897510     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.86.265     Document Type: Review

References (103)

1. The physiological activity of adenine compounds with special reference to their action upon mammalian heart
2. Cardiac nucleotides in hypoxia: Possible role in regulation of coronary blood flow
3. Purinergic systems
4. Cardiovascular purinoceptors
5. Ischemic preconditioning increases adenosine release and 5'-nucleotidase activity during myocardial ischemia and reperfusion in dogs. Implications for myocardial salvage
6. Effect of ischemic preconditioning on interstitial purine metabolite and lactate accumulation during myocardial ischemia
7. Extracellular adenosine levels and cellular energy metabolism in ischemically preconditioned rat heart
8. A basis for distinguishing two types of purinergic receptor
9. Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells
10. 3 adenosine receptor
11. 1 adenosine receptor in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum and basal ganglia
12. iα-3
13. Neuromodulatory roles of adenosine receptors coupling to the calcium channel and adenylyl cyclase
14. Differential effects of adenosine on pre- and postsynaptic calcium fluxes
15. Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by adenosine analogue
16. On the mechanism of activation of muscarinic K channels by adenosine in isolated atrial cells: Involvement of GTP-binding proteins
17. 1 adenosine receptor of rat testis membranes. Purification and partial characterization
18. 1 adenosine receptor
19. 1 adenosine receptor-adenylate cyclase system
20. The role of adenosine in preconditioning
21. Flow thresholds for extracellular purine catabolite elevation in rat focal ischemia
22. Mechanism of adenosine inhibition of catecholamine-induced responses in heart
23. Cardiac effects of adenosine and adenosine analogs in guinea pig atrial and ventricular preparations: Evidence against a role of cyclic AMP and cyclic GMP
24. Adenosine: A physiological modulator of superoxide anion generation by human neutrophils
25. The effect of an intracoronary infusion of adenosine on cardiac performance, blood supply and on myocardial metabolism in dogs
26. Effects of dipyridamole on myocardial glucose uptake in the newborn lamb
27. Myocardial glucose uptake and breakdown during adenosine-induced vasodilation
28. Adenosine modulates β-adrenergic signal transduction in guinea pig heart ventricular membranes
29. Regulation of calcium slow channels of cardiac and smooth muscles by adenine nucleotides
30. Relationship between adenosine concentration and oxygen supply in rat brain
31. Increases in cerebral interstitial fluid adenosine concentration during hypoxia, local potassium infusion, and ischemia
32. An adenosine analogue, 2-chloroadenosine, protects against long term development of ischemic cell loss in the rat hippocampus
33. Neuroprotective effect of cyclohexyl adenosine in treatment of cerebral ischemia in gerbils
34. Neuroprotective role of adenosine in cerebral ischaemia
35. 1) receptors by caffeine treatment
36. 1 receptor agonist or antagonist in cerebral ischemia
37. 2A adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice
38. An adenosine agonist inhibits and cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus
39. Adenosine decreases aspartate and glutamate release from rat hippocampal slices
40. 3H]-glutamate release from rat hippocampal slices by L-isopropyladenosine
41. How does adenosine inhibit neurotransmitter release?
42. + channels in cerebral ischemic preconditioning
43. Purinergic depression of neurons in different areas of the brain
44. Adenosine modulates a voltage-dependent chloride conductance in cultured neurons
45. 2+ influx in hippocampal neurons by adenosine and its blockade by LTP or ischemia
46. Electrophysiological evidence for adenosine receptors on astrocytes of cultured rat central nervous system
47. Comparative effects of caffeine and L-phenylisopropyladenosine on local cerebral glucose utilization in the rat
48. The effect of cyclohexyladenosine on local cerebral blood flow and glucose utilization in the conscious rat
49. Adenosine in the control of the cerebral circulation
50. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
51. ATP channel
52. Infarct limitation of the second window of protection in a conscious rabbit model
53. Blockade of ischemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate
54. 1 adenosine receptors in rabbit heart
55. Ischemic preconditioning reduces infarct size in swine myocardium
56. Adaptation to ischemia during percutaneous transluminal coronary angioplasty. Clinical, hemodynamic, and metabolic features
57. Effect of angina pectoris on myocardial protection in patients with reperfused anterior wall myocardial infarction: Retrospective clinical evidence of preconditioning
58. Chelerythine, a highly selective protein kinase C inhibitor, blocks the antiinfarct effect of ischemic preconditioning in rabbit hearts
59. Effect of adenosine receptor blockade: Preventing protective preconditioning depends on time of initiation
60. 3 receptors
61. 3 receptors in protection of isolated human atrial muscle against stimulated ischaemia
62. 3 receptor
63. Preconditioning protects ischemic rabbit heart by protein kinase C activation
64. Protection of ischemic preconditioning is dependent upon a critical timing sequence of protein kinase C activation
65. Direct evidence that ischemic preconditioning does not cause protein kinase C translocation in rabbit heart
66. 1-receptor-independent activation of protein kinase C in acute myocardial ischemia: Mechanisms for sensitization of the adenylyl cyclase system
67. Tumor-promoting phorbol esters inhibit cardiac functions and induce redistribution of protein kinase C in perfused beating rat heart
68. Ischemic preconditioning induces selective translocation of protein kinase C isoforms epsilon and eta in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity
69. ATP channel
70. ATP channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs
71. ATP opener cromakalim is not correlated with ischemic myocardial action potential duration
72. Potassium channels and preconditioning of isolated rabbit cardiomyocytes: Effects of glyburide and pinacidil
73. + channels: Possible mechanism of cardio-protection
74. + channels in insulinoma cells: Activation by somatostatin and protein kinase C and the role of camp
75. ATP channel
76. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts
77. Protein tyrosine kinase is downstream of protein kinase C for ischemic preconditioning's anti-infarct effect in the rabbit heart
78. Activation of MAPKAP kinase-2 by adenosine in rat heart
79. Activation of mitogen activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by adenosine in the perfused rat heart
80. Activation of phospholipase C via adenosine receptors provide synergistic signals for secretion in antigen-stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor
81. 3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells
82. 3 receptor involvement
83. In vitro ischaemic preconditioning of isolated rabbit cardiomyocytes: Effects of selective adenosine receptor blockade and calphostin C
84. Oxygen-derived free radicals and myocardial reperfusion injury: An overview
85. Adenosine acts as an endogenous activator of the cellular antioxidant defense system
86. Adenosine, antioxidant enzymes and cytoprotection
87. Expression and function of adenosine receptors in the chinchilla cochlea
88. Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damage to the auditory hair cells
89. R-phenylisopropyladenosine attenuates noise-induced hearing loss in the chinchilla
90. Age-related reductions in the activities of antioxidant enzymes in the rat inferior colliculus
91. 1 adenosine receptor expression by activating nuclear factor κB
92. TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NFkB
93. Upregulation of adenosine receptors in the cochlea by cisplatin
94. 1 receptors in rat testes
95. 1 adenosine receptor expression in porcine proximal tubular epithelial (LLC-PK1) cells
96. 2A adenosine receptors in PC12 cells
97. 2AAR adenosine receptor gene
98. Regulation of androgen action by receptor gene inhibition
99. Distinct NF-kappa B/Rel transcription factors are responsible for tissue-specific and inducible gene activation
100. Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invarient chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits
101. 2B receptors: A novel therapeutic target in asthma?
102. 3 receptor expression and function in eosinophils
103. 3 adenosine receptor expression in RBL-2H3 cells by inflammatory mediators