Binding of the long pentraxin PTX3 to factor H: Interacting domains and function in the regulation of complement activation

Journal of Immunology

Volumn 181, Issue 12, 2008, Pages 8433-8440

  Deban, Livija ^a   Jarva, Hanna ^b,c   Lehtinen, Markus J ^b   Bottazzi, Barbara ^a   Bastone, Antonio ^d   Doni, Andrea ^a   Jokiranta, T Sakari ^b   Mantovani, Alberto ^a,e   Meri, Seppo ^b,c  

^a HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^b UNIVERSITY OF HELSINKI   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C3B; COMPLEMENT FACTOR H; FIBRINOGEN; PENTRAXIN 3; ACUTE PHASE PROTEIN; C REACTIVE PROTEIN; COMPLEMENT FACTOR H, HUMAN; SERUM AMYLOID P; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; CHO CELL; COMPLEMENT ALTERNATIVE PATHWAY; CONSENSUS SEQUENCE; CRICETULUS; HAMSTER; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

ACUTE-PHASE PROTEINS; ANIMALS; BINDING, COMPETITIVE; C-REACTIVE PROTEIN; CHO CELLS; COMPLEMENT FACTOR H; COMPLEMENT PATHWAY, ALTERNATIVE; CONSENSUS SEQUENCE; CRICETINAE; CRICETULUS; HUMANS; JURKAT CELLS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; REPETITIVE SEQUENCES, AMINO ACID; SERUM AMYLOID P-COMPONENT;

EID: 58849092356     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.12.8433     Document Type: Article

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