Identification of an antiangiogenic FGF2-binding site in the N terminus of the soluble pattern recognition receptor PTX3

Journal of Biological Chemistry

Volumn 281, Issue 32, 2006, Pages 22605-22613

  Camozzi, Maura ^a   Rusnati, Marco ^a   Bugatti, Antonella ^a   Bottazzi, Barbara ^b   Mantovani, Alberto ^b,c   Bastone, Antonio ^d   Inforzato, Antonio ^e   Vincenti, Silvia ^f   Bracci, Luisa ^g   Mastroianni, Domenico ^h   Presta, Marco ^a,i  

^a UNIVERSITY OF BRESCIA   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

^f Sigma Tau SpA   (Italy)

^g UNIVERSITY OF SIENA   (Italy)

^h Tecnogen SpA   (Italy)

ⁱ General Pathology   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ANTIBODIES; BIOSENSORS; IMMUNOLOGY; PATTERN RECOGNITION;

ENDOTHELIAL CELLS (EC); FIBROBLAST GROWTH FACTOR-2 (FGF2); LONG-PENTRAXIN 3 (PTX3); MITOGENIC ACTIVITY;

CELLS;

FIBROBLAST GROWTH FACTOR 2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MNB4; PATTERN RECOGNITION RECEPTOR; PATTERN RECOGNITION RECEPTOR PTX3; PENTRAXIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ARTICLE; BINDING SITE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVATION; DRUG ANTAGONISM; DRUG PROTEIN BINDING; ENDOTHELIUM CELL; EPITOPE MAPPING; NONHUMAN; PATTERN RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; RETROVIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; C-REACTIVE PROTEIN; CATTLE; COMPLEMENT C1Q; EPITOPES; FIBROBLAST GROWTH FACTOR 2; HUMANS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PATHOLOGIC; SEQUENCE HOMOLOGY, AMINO ACID; SERUM AMYLOID P-COMPONENT;

EID: 33747336999     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M601023200     Document Type: Article

References (26)

1. Garlanda, C., Bottazzi, B., Bastone, A., and Mantovani, A. (2005) Annu. Rev. Immunol. 23, 337-366
2. Steel, D. M., and Whitehead, A. S. (1994) Immunol. Today 15, 81-88
3. Nauta, A. J., Daha, M. R., van Kooten, C., and Roos, A. (2003) Trends Immunol. 24, 148-154
4. Goodman, A. R., Cardozo, T., Abagyan, R., Altmeyer, A., Wisniewski, H. G., and Vilcek, J. (1996) Cytokine Growth Factor Rev. 7, 191-202
5. Breviario, F., d'Aniello, E. M., Golay, J., Peri, G., Bottazzi, B., Bairoch, A., Saccone, S., Marzella, R., Predazzi, V., and Rocchi, M. (1992) J. Biol. Chem. 267, 22190-22197
6. Lee, G. W., Lee, T. H., and Vilcek, J. (1993) J. Immunol. 150, 1804-1812
7. Basile, A., Sica, A., d'Aniello, E., Breviario, F., Garrido, G., Castellano, M., Mantovani, A., and Introna, M. (1997) J. Biol. Chem. 272, 8172-8178
8. Salustri, A., Garlanda, C., Hirsch, E., De Acetis, M., Maccagno, A., Bottazzi, B., Doni, A., Bastone, A., Mantovani, G., Beck Peccoz, P., Salvatori, G., Mahoney, D. J., Day, A. J., Siracusa, G., Romani, L., and Mantovani, A. (2004) Development 131, 1577-1586
9. Garlanda, C., Hirsch, E., Bozza, S., Salustri, A., De Acetis, M., Nota, R., Maccagno, A., Riva, F., Bottazzi, B., Peri, G., Doni, A., Vago, L., Botto, M., De Santis, R., Carminati, P., Siracusa, G., Altruda, F., Vecchi, A., Romani, L., and Mantovani, A. (2002) Nature 420, 182-186
10. Mantovani, A., Garlanda, C., and Bottazzi, B. (2003) Vaccine 21, Suppl. 2, S43-S47
11. Gerwins, P., Skoldenberg, E., and Claesson-Welsh, L. (2000) Crit. Rev. Oncol. Hematol. 34, 185-194
12. Presta, M., Dell'Era, P., Mitola, S., Moroni, E., Ronca, R., and Rusnati, M. (2005) Cytokine Growth Factor Rev. 16, 159-178
13. Rusnati, M., Camozzi, M., Moroni, E., Bottazzi, B., Peri, G., Indraccolo, S., Amadori, A., Mantovani, A., and Presta, M. (2004) Blood 104, 92-99
14. Camozzi, M., Zacchigna, S., Rusnati, M., Coltrini, D., Ramirez-Correa, G., Bottazzi, B., Mantovani, A., Giacca, M., and Presta, M. (2005) Arterioscler. Thromb. Vasc. Biol. 25, 1837-1842
15. Bottazzi, B., Vouret-Craviari, V., Bastone, A., De Gioia, L., Matteucci, C., Peri, G., Spreafico, F., Pausa, M., D'Ettorre, C., Gianazza, E., Tagliabue, A., Salmona, M., Tedesco, F., Introna, M., and Mantovani, A. (1997) J. Biol. Chem. 272, 32817-32823
16. Isacchi, A., Statuto, M., Chiesa, R., Bergonzoni, L., Rusnati, M., Sarmientos, P., Ragnotti, G., and Presta, M. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 2628-2632
17. Peri, G., Introna, M., Corradi, D., Iacuitti, G., Signorini, S., Avanzini, F., Pizzetti, F., Maggioni, A. P., Moccetti, T., Metra, M., Cas, L. D., Ghezzi, P., Sipe, J. D., Re, G., Olivetti, G., Mantovani, A., and Latini, R. (2000) Circulation 102, 636-641
18. Presta, M., Maier, J. A., Rusnati, M., and Ragnotti, G. (1989) J. Cell Physiol. 141, 517-526
19. Frank, R., and Overwin, H. (1996) Methods Mol. Biol. 66, 149-169
20. Knoll, A., Schmidt, S., Chapman, M., Wiley, D., Bulgrin, J., Blank, J., and Kirchner, L. (1999) Microvasc. Res. 58, 1-9
21. Blotnick, S., Peoples, G. E., Freeman, M. R., Eberlein, T. J., and Klagsbrun, M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 2890-2894
22. Peoples, G. E., Blotnick, S., Takahashi, K., Freeman, M. R., Klagsbrun, M., and Eberlein, T. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 6547-6551
23. Reidy, M. A., Fingerle, J., and Lindner, V. (1992) Circulation 86, Suppl. 6, III43-46
24. Logan, A., and Berry, M. (1993) Trends Pharmacol. Sci. 14, 337-342
25. Ravizza, T., Moneta, D., Bottazzi, B., Peri, G., Garlanda, C., Hirsch, E., Richards, G. J., Mantovani, A., and Vezzani, A. (2001) Neuroscience 105, 43-53
26. Rolph, M. S., Zimmer, S., Bottazzi, B., Garlanda, C., Mantovani, A., and Hansson, G. K. (2002) Arterioscler. Thromb. Vasc. Biol. 22, e10-14