Chemotherapeutic sensitization by endoplasmic reticulum stress: Increasing the efficacy of taxane against prostate cancer

Cancer Biology and Therapy

Volumn 8, Issue 2, 2009, Pages 146-152

  Wu, Yue ^a   Fabritius, Melissa ^a   Ip, Clement ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Chemosensitization; Endoplasmic reticulum stress; Prostate cancer; Selenium; Taxanes

Indexed keywords

CALCIUM; CASPASE 8; CASPASE 9; DOCETAXEL; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; METHYLSELENINIC ACID; PACLITAXEL; SELENIUM DERIVATIVE; SMALL INTERFERING RNA; TAUROURSODEOXYCHOLIC ACID; TAXANE DERIVATIVE; THAPSIGARGIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CELL KILLING; CHEMICAL STRESS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG SENSITIZATION; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; PROSTATE CANCER; UPREGULATION;

EID: 58749113252     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.8.2.7087     Document Type: Article

References (50)

1. Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007; 8:519-29.
2. Lee AS, Hendershot LM. ER stress and cancer. Cancer Biol Ther 2006; 5:721-2.
3. Ma Y, Hendershot LM. The role of the unfolded protein response in tumour development: friend or foe? Nat Rev Cancer 2004; 4:966-77.
4. Mann MJ, Hendershot LM. UPR activation alters chemosensitivity of tumor cells. Cancer Biol Ther 2006; 5:736-40.
5. Scriven P, Brown NJ, Pockley AG, Wyld L. The unfolded protein response and cancer: a brighter future unfolding? J Mol Med 2007; 85:331-41.
6. Jiang CC, Chen LH, Gillespie S, et al. Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by upregulation of TRAIL-R2 via the unfolded protein response. Cancer Res 2007; 67:5880-8.
7. Shiraishi T, Yoshida T, Nakata S, et al. Tunicamycin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human prostate cancer cells. Cancer Res 2005; 65:6364-70.
8. Ledoux S, Yang R, Friedlander G, Laouari D. Glucose depletion enhances P-glycoprotein expression in hepatoma cells: role of endoplasmic reticulum stress response. Cancer Res 2003; 63:7284-90.
9. Ranganathan AC, Zhang L, Adam AP, Aguirre-Ghiso JA. Functional coupling of p38-induced upregulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells. Cancer Res 2006; 66:1702-11.
10. He Q, Lee DI, Rong R, et al. Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway. Oncogene 2002; 21:2623-33.
11. Isaacs JT. New strategies for the medical treatment of prostate cancer. BJU Int 2005; 96:35-40.
12. Park HJ, Makepeace CM, Lyons JC, Song CW. Effect of intracellular acidity and ionomycin on apoptosis in HL-60 cells. Eur J Cancer 1996; 32:540-6.
13. Yoshida T, Shiraishi T, Horinaka M, Wakada M, Sakai T. Glycosylation modulates TRAIL-R1/death receptor 4 protein: different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin. Oncol Rep 2007; 18:1239-42.
14. Wu Y, Zhang H, Dong Y, Park YM, Ip C. Endoplasmic reticulum stress signal mediators are targets of selenium action. Cancer Res 2005; 65:9073-9.
15. Zu K, Bihani T, Lin A, Park YM, Mori K, Ip C. Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells. Oncogene 2006; 25:546-54.
16. Cao S, Durrani FA, Rustum YM. Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts. Clin Cancer Res 2004; 10:2561-9.
17. Hu H, Jiang C, Ip C, Rustum YM, Lu J. Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells. Clin Cancer Res 2005; 11:2379-88.
18. Azrak RG, Frank CL, Ling X, Li F, Foster BA, Rustum YM. The mechanism of methylselenocysteine (MSeC) and docetaxel synergistic activity in prostate cancer cells. Mol Cancer Ther 2006; 5:2540-8.
19. Vadgama JV, Wu Y, Shen D, Hsia S, Block J. Effect of selenium in combination with Adriamycin or Taxol on several different cancer cells. Anticancer Res 2000; 20:1391-414.
20. Ryan CJ, Eisenberger M. Chemotherapy for hormone-refractory prostate cancer: now it's a question of "when?". J Clin Oncol 2005; 23:8242-6.
21. Kibel AS. An interdisciplinary approach to treating prostate cancer. Urology 2005; 65:13-8.
22. Lee JS, Ma YB, Choi KS, et al. Neural network-based analysis of thiol proteomics data in identifying potential selenium targets. Prep Biochem Biotechnol 2006; 36:37-64.
23. Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 2006; 313:1137-40.
24. Wu Y, Zu K, Warren MA, Wallace PK, Ip C. Delineating the mechanism by which selenium deactivates Akt in prostate cancer cells. Mol Cancer Ther 2006; 5:246-52.
25. Rao RV, Ellerby HM, Bredesen DE. Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 2004; 11:372-80.
26. Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004; 11:381-9.
27. Fakih MG, Pendyala L, Smith PF, et al. A phase I and pharmacokinetic study of fixed-dose selenomethionine and irinotecan in solid tumors. Clin Cancer Res 2006; 12:1237-44.
28. Hitomi J, Katayama T, Eguchi Y, et al. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol 2004; 165:347-56.
29. Rao RV, Hermel E, Castro-Obregon S, et al. Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation. J Biol Chem 2001; 276:33869-74.
30. 2+ signals, mitochondrial fission and sensitization to apoptosis. Cell Death Differ 2003; 10:1287-9.
31. Kidd VJ, Lahti JM, Teitz T. Proteolytic regulation of apoptosis. Semin Cell Dev Biol 2000; 11:191-201.
32. Gil-Parrado S, Fernandez-Montalvan A, Assfalg-Machleidt I, et al. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem 2002; 277:27217-26.
33. Mandic A, Viktorsson K, Strandberg L, et al. Calpain-mediated Bid cleavage and calpain-independent Bak modulation: two separate pathways in cisplatin-induced apoptosis. Mol Cell Biol 2002; 22:3003-13.
34. Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002; 296:1655-7.
35. Downward J. How BAD phosphorylation is good for survival. Nat Cell Biol 1999; 1:33-5.
36. Huang H, Tindall DJ. Dynamic FoxO transcription factors. J Cell Sci 2007; 120:2479-87.
37. McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ. Gadd153 sensitizes cells to endoplasmic reticulum stress by downregulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 2001; 21:1249-59.
38. He Q, Luo X, Jin W, et al. Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP. Oncogene 2007.
39. Yamaguchi H, Wang HG. CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells. J Biol Chem 2004; 279:45495-502.
40. Lee AS. GRP78 induction in cancer: therapeutic and prognostic implications. Cancer Res 2007; 67:3496-9.
41. Li J, Lee AS. Stress induction of GRP78/BiP and its role in cancer. Curr Mol Med 2006; 6:45-54.
42. Fu Y, Lee AS. Glucose regulated proteins in cancer progression, drug resistance and immunotherapy. Cancer Biol Ther 2006; 5:741-4.
43. Fu Y, Li J, Lee AS. GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis. Cancer Res 2007; 67:3734-40.
44. Lee E, Nichols P, Spicer D, Groshen S, Yu MC, Lee AS. GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer. Cancer Res 2006; 66:7849-53.
45. Ermakova SP, Kang BS, Choi BY, et al. (-)-Epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78. Cancer Res 2006; 66:9260-9.
46. Pyrko P, Schönthal AH, Hofman FM, Chen TC, Lee AS. The unfolded protein response regulator GRP78/BIP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res 2007; 67:9809-16.
47. Ip C, Thompson HJ, Zhu Z, Ganther HE. In vitro and in vivo studies of methylseleninic acid: evidence that a monomethylated selenium metabolite is critical for cancer chemoprevention. Cancer Res 2000; 60:2882-6.
48. Ip C, Dong Y, Ganther HE. New concepts in selenium chemoprevention. Cancer Metastasis Rev 2002; 21:281-9.
49. Li S, Zhou Y, Wang R, Zhang H, Dong Y, Ip C. Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. Mol Cancer Ther 2007; 6:1031-8.
50. Werstuck GH, Lentz SR, Dayal S, et al. Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 2001; 107:1263-73.