Expression of genes involved in GAB Aergic neurotransmission in anoxic crucian carp brain (Carassius carassius)

Physiological Genomics

Volumn 36, Issue 2, 2009, Pages 61-68

  Ellefsen, Stian ^a,b   Stensløkken, Kåre Olav ^c   Fagernes, Cathrine E ^a   Kristensen, Tom A ^a   Nilsson, Göran E ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b INLAND NORWAY UNIVERSITY OF APPLIED SCIENCES   (Norway)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

External RNA control; GABA; GABA receptor; GABA transporter

Indexed keywords

4 AMINOBUTYRIC ACID A ALPHA1 RECEPTOR; 4 AMINOBUTYRIC ACID A ALPHA2 RECEPTOR; 4 AMINOBUTYRIC ACID A ALPHA3 RECEPTOR; 4 AMINOBUTYRIC ACID A ALPHA4 RECEPTOR; 4 AMINOBUTYRIC ACID A ALPHA5 RECEPTOR; 4 AMINOBUTYRIC ACID A ALPHA6 RECEPTOR; 4 AMINOBUTYRIC ACID A BETA2 RECEPTOR; 4 AMINOBUTYRIC ACID A DELTA RECEPTOR; 4 AMINOBUTYRIC ACID A GAMMA2 RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B 1A RECEPTOR; 4 AMINOBUTYRIC ACID B 1B RECEPTOR; 4 AMINOBUTYRIC ACID B 2 RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID CARRIER; 4 AMINOBUTYRIC ACID RECEPTOR; ADENOSINE TRIPHOSPHATE; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER 2; PROTEIN GABARAP 1; PROTEIN GABARAP 2; PROTEIN GAT1; PROTEIN GAT2A; PROTEIN GAT2B; PROTEIN GAT3; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID BRAIN LEVEL; 4 AMINOBUTYRIC ACID METABOLISM; 4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HYPOXIA; CARASSIUS CARASSIUS; CARP; CONTROLLED STUDY; ENZYME ACTIVITY; GABAERGIC TRANSMISSION; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; BRAIN; CARPS; CELL HYPOXIA; FISH PROTEINS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; RECEPTORS, GABA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYNAPTIC TRANSMISSION;

CARASSIUS; CARASSIUS CARASSIUS; MAMMALIA;

EID: 58649103992     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.90301.2008     Document Type: Article

References (44)

1. Bettler B, Kaupmann K, Mosbacher J, Gassmann M. Molecular structure and physiological functions of GABA(B) receptors. Physiol Rev 84: 835-867, 2004.
2. Bianchi MT, Macdonald RL. Slow phases of GABAA receptor desensitization: structural determinants and possible relevance for synaptic function. J Physiol 544: 3-18, 2002.
3. Borden LA, Smith KE, Hartig PR, Branchek TA, Weinshank RL. Molecular heterogeneity of the gamma-aminobutyric acid (GABA) transport system. Cloning of two novel high affinity GABA transporters from rat brain. J Biol Chem 267: 21098-21104, 1992.
4. Brown N, Kerby J, Bonnert TP, Whiting PJ, Wafford KA. Pharmacological characterization of a novel cell line expressing human alpha4-beta3-delta GABAA receptors. Br J Pharmacol 136: 965-974, 2002.
5. Clark JA, Deutch AY, Gallipoli PZ, Amara SG. Functional expression and CNS distribution of a [beta]-alanine-sensitive neuronal GABA transporter. Neuron 9: 337-348, 1992.
6. Conti F, Minelli A, Melone M. GABA transporters in the mammalian cerebral cortex: localization, development and pathological implications. Brain Res Rev 45: 196-212, 2004.
7. Dalby NO. Inhibition of gamma-aminobutyric acid uptake: anatomy, physiology and effects against epileptic seizures. Eur J Pharmacol 479: 127-137, 2003.
8. Ellefsen S, Sandvik GK, Larsen HK, Stensl0kken KO, Hov DAS, Kristensen TA, Nilsson GE. Expression of genes involved in excitatory neurotransmission in anoxic crucian carp brain (Carassius carassius). Physiol Genomics 35: 5-17, 2008.
9. Ellefsen S, Stenslokken KO, Sandvik GK, Kristensen TA, Nilsson GE. Improved normalization of real time RT PCR data using an external RNA control. Anal Biochem 376: 83-93, 2008.
10. Esclapez M, Houser CR. Up-regulation of GAD65 and GAD67 in remaining hippocampal GABA neurons in a model of temporal lobe epilepsy. J Comp Neurol 412: 488-505, 1999.
11. Everitt AB, Luu T, Cromer B, Tierney ML, Birnir B, Olsen RW, Gage PW. Conductance of recombinant GABA channels is increased in cells co-expressing GABAA A receptor-associated protein. J Biol Chem 279: 21701-21706, 2004.
12. Farrant M, Nusser Z. Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors. Nat Rev Neurosci 6: 215-229, 2005.
13. Feng HJ, Macdonald RL. Multiple actions of propofol on alpha-beta-gamma and alpha-beta-delta GABAA receptors. Mol Pharmacol 66: 1517-1524, 2004.
14. Furtinger S, Bettler B, Sperk G. Altered expression of GABA(B) receptors in the hippocampus after kainic-acid-induced seizures in rats. Mol Brain Res 113: 107-115, 2003.
15. Glykys J, Mody I. The main source of ambient GABA responsible for tonic inhibition in the mouse hippocampus. J Physiol 582: 1163-1178, 2007.
16. Greenbaum D, Colangelo C, Williams K, Gerstein M. Comparing protein abundance and mRNA expression levels on a genomic scale. Genome Biol 4: 117, 2003.
17. Guastella J, Nelson N, Nelson H, Czyzyk L, Keynan S, Miedel MC, Davidson N, Lester HA, Kanner BI. Cloning and expression of a rat brain GABA transporter. Science 249: 1303-1306, 1990.
18. Hirao T, Morimoto K, Yamamoto Y, Watanabe T, Sato H, Sato K, Sato S, Yamada N, Tanaka K, Suwaki H. Time-dependent and regional expression of GABA transporter mRNAs following amygdala-kindled seizures in rats. Mol Brain Res 54: 49 -55, 1998.
19. Hylland P, Nilsson GE. Extracellular levels of amino acid neurotransmitters during anoxia and forced energy deficiency in crucian carp brain. Brain Res 823: 49-58, 1999.
20. Hyvärinen H, Holopainen IJ, Piironen J. Anaerobic wintering of crucian carp (Carassius carassius L.) - 1. Annual dynamics of glycogen reserves in nature. Comp Biochem Physiol A 82A: 797-803, 1985.
21. Jansen R, Greenbaum D, Gerstein M. Relating whole-genome expression data with protein-protein interactions. Genome Res 12: 37-46, 2002.
22. Jursky F, Nelson N. Developmental expression of the neurotransmitter transporter GAT3. J Neuroscience Res 55: 394-399, 1999.
23. Liu Q, Mandiyan S, Nelson H, Nelson N. A family of genes encoding neurotransmitter transporters. Proc Natl Acad Sci USA 89: 6639 -6643, 1992.
24. Liu QR, Lopez-Corcuera B, Mandiyan S, Nelson H, Nelson N. Molecular characterization of four pharmacologically distinct gamma-ami-nobutyric acid transporters in mouse brain [corrected]. J Biol Chem 268: 2106-2112, 1993.
25. Lutz PL, Leone-Kabler SL. Upregulation of the GABAA/benzodiazepine receptor during anoxia in the freshwater turtle brain. Am J Physiol Regul Integr Comp Physiol 268: R1332-R1335, 1995.
26. Lutz PL, Nilsson GE, Prentice HM. The Brain Without Oxygen: Causes of Failure - Molecular and Physiological Mechanisms for Survival. Dordrecht, The Netherlands: Kluwer Academic, 2003.
27. Melone M, Cozzi A, Pellegrini-Giampietro DE, Conti F. Transient focal ischemia triggers neuronal expression of GAT-3 in the rat perilesional cortex. Neurobiol Dis 14: 120-132, 2003.
28. Minelli A, Barbaresi P, Conti F. Postnatal development of high-affinity plasma membrane GABA transporters GAT-2 and GAT-3 in the rat cerebral cortex. Dev Brain Res 142: 7-18, 2003.
29. Minelli A, Brecha NC, Karschin C, DeBiasi S, Conti F. GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex. J Neurosci 15: 7734 -7746, 1995.
30. Minelli A, DeBiasi S, Brecha NC, Vitellaro Zuccarello L, Conti F. GAT-3, a high-affinity GABA plasma membrane transporter, is localized to astrocytic processes, and it is not confined to the vicinity of GABAergic synapses in the cerebral cortex. J Neurosci 16: 6255-6264, 1996.
31. Nilsson GE. Evidence for a role of GABA in metabolic depression during anoxia in crucian carp (Carassius carassius). J Exp Biol 164: 243-259, 1992.
32. Nilsson GE. Long-term anoxia in crucian carp: changes in the levels of amino acid and monoamine neurotransmitters in the brain, catecholamines in chromaffin tissue, and liver glycogen. J Exp Biol 150: 295-320, 1990.
33. Nilsson GE, Lutz PL. Anoxia tolerant brains. J Cereb Blood Flow Metab 24: 475-486, 2004.
34. Nilsson GE, Lutz PL. Release of inhibitory neurotransmitters in response to anoxia in turtle brain. Am J Physiol Regul Integr Comp Physiol 261: R32-R37, 1991.
35. Park JB, Skalska S, Stern JE. Characterization of a novel tonic gammaaminobutyric acid A receptor-mediated inhibition in magnocellular neurosecretory neurons and its modulation by glia. Endocrinology 147: 3746-3760, 2006.
36. Pierce KL, Premont RT, Lefkowitz RJ. Seven-transmembrane receptors. Nature Rev Mol Cell Biol 3: 639-650, 2002.
37. Ramakers C, Ruijter JM, Deprez RH, Moorman AF. Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci Lett 339: 62-66, 2003.
38. Redecker C, Wang W, Fritschy JM, Witte OW. Widespread and long-lasting alterations in GABAA-receptor subtypes after focal cortical infarcts in rats: mediation by NMDA-dependent processes. J Cereb Blood Flow Metab 22: 1463-1475, 2002.
39. Rivera C, Li H, Thomas-Crusells J, Lahtinen H, Viitanen T, Nanobashvili A, Kokaia Z, Airaksinen MS, Voipio J, Kaila K, Saarma M. BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion. J Cell Biol 159: 747-752, 2002.
40. Rivera C, Voipio J, Payne JA, Ruusuvuori E, Lahtinen H, Lamsa K, Pirvola U, Saarma M, Kaila K. The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. Nature 397: 251-255, 1999.
41. Schwartz-Bloom RD, Sah R. -γ-Aminobutyric acidA neurotransmission and cerebral ischemia. J Neurochem 77: 353-371, 2001.
42. Sperk G, Schwarzer C, Tsunashima K, Kandlhofer S. Expression of GABAA receptor subunits in the hippocampus of the rat after kainic acid-induced seizures. Epilepsy Res 32: 129-139, 1998.
43. Thompson JW, Prentice HM, Lutz PL. Regulation of extracellular glutamate levels in the long-term anoxic turtle striatum: coordinated activity of glutamate transporters, adenosine, K-ATP channels and GABA. J Biomed Sci 14: 809-817, 2007.
44. Zhu XM, Ong WY. Changes in GABA transporters in the rat hippocampus after kainate-induced neuronal injury: decrease in GAT-1 and GAT-3 but upregulation of betaine/GABA transporter BGT-1. JNeurosci Res 77: 402-409, 2004.