Synthesis and biological activities of high affinity taxane-based fluorescent probes

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 3, 2009, Pages 751-754

  Li, Xuan ^a,b   Barasoain, Isabel ^c   Matesanz, Ruth ^c   Fernando Diaz J ^c   Fang, Wei Shuo ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Cephalomannine; Difluorescein; Fluorescein; Fluorescence; High affinity taxanes; Paclitaxel

Indexed keywords

CEPHALOMANNINE; DOCETAXEL; FLUORESCEIN; FLUORESCENT DYE; PACLITAXEL; TAXANE DERIVATIVE; TUBULIN;

ARTICLE; BINDING AFFINITY; CELL KILLING; CONJUGATION; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; MICROTUBULE; THERMODYNAMICS; TUMOR CELL;

ANISOTROPY; BRIDGED COMPOUNDS; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; FLUORESCEIN; FLUORESCENT DYES; LIGANDS; MICROTUBULES; MODELS, CHEMICAL; PLANT EXTRACTS; TAXOIDS; TEMPERATURE; THERMODYNAMICS; TUBULIN;

EID: 58549096682     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.12.018     Document Type: Article

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