Synthesis and evaluation of [14C]-labelled and fluorescent-tagged paclitaxel derivatives as new biological probes

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 11, 1998, Pages 2193-2204

  Rao, Ch Srinivasa ^a   Chu, Jao Jia ^a   Liu, Rai Shung ^a   Lai, Yiu Kay ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Antitumor compds; Chemotherapy; Fluorescence; Labelling; Substituent effects

Indexed keywords

DOCETAXEL; FLUORESCEIN ISOTHIOCYANATE; PACLITAXEL; PACLITAXEL DERIVATIVE; ANTINEOPLASTIC AGENT; CARBON; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; FLUORESCENT DYE; RHODAMINE;

ARTICLE; CYTOTOXICITY; DRUG ACCUMULATION; DRUG SYNTHESIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; ACETYLATION; CELL CULTURE; CELL CYCLE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; ISOTOPE LABELING; LUNG TUMOR; METHODOLOGY; SYNTHESIS; TRANSPORT AT THE CELLULAR LEVEL;

ACETYLATION; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CARBON RADIOISOTOPES; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; CELL SURVIVAL; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HUMANS; INDICATORS AND REAGENTS; ISOTOPE LABELING; LUNG NEOPLASMS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PACLITAXEL; RHODAMINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0031593584     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00158-8     Document Type: Article

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