Analysis of the association of IL1B (C+3954T) and IL1RN (intron 2) polymorphisms with dental implant loss in a Brazilian population

Clinical Oral Implants Research

Volumn 20, Issue 2, 2009, Pages 208-217

  Montes, Claudia Cristina ^a   Alvim Pereira, Fabiano ^b   De Castilhos, Bruno Borges ^b   Sakurai, Marcos Luciano Lopes ^b   Olandoski, Marcia ^b   Trevilatto, Paula Cristina ^b  

^a Centro de Ensino Superior Dos Campos Gerais (CESCAGE)   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

Author keywords

Dental implant loss; IL 1 genetic polymorphisms; Risk factors

Indexed keywords

CYTOSINE; IL1RN PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; THYMINE;

ADULT; AGED; ARTICLE; BRAZIL; CASE CONTROL STUDY; CLASSIFICATION; COMPARATIVE STUDY; DENTAL SURGERY; DENTITION; EDENTULOUSNESS; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; INTRON; MALE; MIDDLE AGED; PERIODONTICS; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SMOKING; TOOTH IMPLANTATION;

ADULT; AGED; AGED, 80 AND OVER; BRAZIL; CASE-CONTROL STUDIES; CYTOSINE; DENTAL IMPLANTS; DENTAL RESTORATION FAILURE; DENTITION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; INTRONS; JAW, EDENTULOUS; MALE; MIDDLE AGED; PERIODONTAL INDEX; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SMOKING; THYMINE;

EID: 58449131294     PISSN: 09057161     EISSN: 16000501     Source Type: Journal    
DOI: 10.1111/j.1600-0501.2008.01629.x     Document Type: Article

References (68)

1. ABEP (2003).
2. Aboyoussef, H., Carter, C., Jandinski, J.J. Panagakos, F.S. (1998) Detection of prostaglandin E2 and matrix metalloproteinases in implant crevicular fluid. The International Journal of Oral & Maxillofacial Implants 13 : 689 696.
3. Adell, R., Eriksson, B., Lekholm, U., Branemark, P.I. Jemt, T. (1990) Long-term follow-up study of osseointegrated implants in the treatment of totally edentulous jaws. The International Journal of Oral & Maxillofacial Implants 5 : 347 359.
4. Aidar, M. Line, S.R. (2007) A simple and cost-effective protocol for DNA isolation from buccal epithelial cells. Brazilian Dental Journal 18 : 148 152.
5. Albrektsson, T. (1983) Direct bone anchorage of dental implants. Journal of Prosthetyc Dentistry 50 : 255 261.
6. Albrektsson, T., Branemark, P.I., Hansson, H.A. Lindstrom, J. (1981) Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthopaedica Scandinavica 52 : 155 170.
7. Albrektsson, T. Hansson, H.A. (1986) An ultrastructural characterization of the interface between bone and sputtered titanium or stainless steel surfaces. Biomaterials 7 : 201 205.
8. Albrektsson, T., Jansson, T. Lekholm, U. (1986) Osseointegrated dental implants. Dental Clinics of North America 30 : 151 174.
9. Alvim-Pereira, F., Montes, C.C., Mira, M.T. Trevilatto, P.C. (2008a) Genetic susceptibility to dental implant failure: a critical review. The International Journal of Oral & Maxillofacial Implants 23 : 409 416.
10. Alvim-Pereira, F., Montes, C.C., Olandoski, M. Trevilatto, P.C. (2008b) Analysis of association of clinical aspects and VDR gene polymorphism with dental implant loss. Clinical Oral Implants Research 19 : 786 795.
11. Andus, T., Daig, R., Vogl, D., Aschenbrenner, E., Lock, G., Hollerbach, S., Kollinger, M., Scholmerich, J. Gross, V. (1997) Imbalance of the interleukin 1 system in colonic mucosa - association with intestinal inflammation and interleukin 1 receptor antagonist [corrected] genotype 2. Gut 41 : 651 657.
12. Bain, C.A. (1996) Smoking and implant failure - benefits of a smoking cessation protocol. The International Journal of Oral & Maxillofacial Implants 11 : 756 759.
13. Bain, C.A. Moy, P.K. (1993) The association between the failure of dental implants and cigarette smoking. The International Journal of Oral & Maxillofacial Implants 8 : 609 615.
14. Branemark, P.I., Adell, R., Breine, U., Hansson, B.O., Lindstrom, J. Ohlsson, A. (1969) Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scandinavian Journal of Plastic and Reconstructive Surgery 3 : 81 100.
15. Campos, M.I., Santos, M.C., Trevilatto, P.C., Scarel-Caminaga, R.M., Bezerra, F.J. Line, S.R. (2005) Evaluation of the relationship between interleukin-1 gene cluster polymorphisms and early implant failure in non-smoking patients. Clinical oral Implants Research 16 : 194 201.
16. De Sanctis, M. Zucchelli, G. (2000) Interleukin-1 gene polymorphisms and long-term stability following guided tissue regeneration therapy. Journal of Perodontology 71 : 606 613.
17. Dinarello, C.A. (1991) Inflammatory cytokines: interleukin-1 and tumor necrosis factor as effector molecules in autoimmune diseases. Current Opinion in Immunology 3 : 941 948.
18. el Askary, A.S., Meffert, R.M. Griffin, T. (1999) Why do dental implants fail? Part I. Implant Dentistry 8 : 173 185.
19. Ellen, R.P. (1998) Microbial colonization of the peri-implant environment and its relevance to long-term success of osseointegrated implants. The International Journal of Prosthodontics 11 : 433 441.
20. Esposito, M., Coulthard, P., Thomsen, P. Worthington, H.V. (2005a) Interventions for replacing missing teeth: different types of dental implants. Cochrane Database of Systematic Reviews 16 : CD004152.
21. Esposito, M., Coulthard, P., Thomsen, P. Worthington, H.V. (2005b) The role of implant surface modifications, shape and material on the success of osseointegrated dental implants. A Cochrane systematic review. The European Journal of Prosthodontics and Restorative Dentistry 13 : 15 31.
22. Esposito, M., Hirsch, J.M., Lekholm, U. Thomsen, P. (1998a) Biological factors contributing to failures of osseointegrated oral implants. (I). Success criteria and epidemiology. European Journal of Oral Sciences 106 : 527 551.
23. Esposito, M., Hirsch, J.M., Lekholm, U. Thomsen, P. (1998b) Biological factors contributing to failures of osseointegrated oral implants. (II). Etiopathogenesis. European Journal of Oral Sciences 106 : 721 764.
24. Esposito, M., Thomsen, P., Ericson, L.E. Lekholm, U. (1999) Histopathologic observations on early oral implant failures. The International Journal of Oral & Maxillofacial Implants 14 : 798 810.
25. Feloutzis, A., Lang, N.P., Tonetti, M.S., Burgin, W., Bragger, U., Buser, D., Duff, G.W. Kornman, K.S. (2003) IL-1 gene polymorphism and smoking as risk factors for peri-implant bone loss in a well-maintained population. Clinical Oral Implants Research 14 : 10 17.
26. Gainet, J., Chollet-Martin, S., Brion, M., Hakim, J., Gougerot-Pocidalo, M.A. Elbim, C. (1998) Interleukin-8 production by polymorphonuclear neutrophils in patients with rapidly progressive periodontitis: an amplifying loop of polymorphonuclear neutrophil activation. Laboratory Investigation 78 : 755 762.
27. Greene, J.C. Vermillion, J.R. (1964) The simplified oral hygiene index. Journal of the American Dental Association 68 : 7 13.
28. Gruica, B., Wang, H.Y., Lang, N.P. Buser, D. (2004) Impact of IL-1 genotype and smoking status on the prognosis of osseointegrated implants. Clinical Oral Implants Research 15 : 393 400.
29. Harada, Y., Watanabe, S., Yssel, H. Arai, K. (1996) Factors affecting the cytokine production of human T cells stimulated by different modes of activation. The Journal of Allergy and Clinical Immunology 98 : S161 S173.
30. Hu, S., Song, Q.B., Yao, P.F., Hu, Q.L., Hu, P.J., Zeng, Z.R. Pang, R.P. (2005) No relationship between IL-1B gene polymorphism and gastric acid secretion in younger healthy volunteers. World Journal of Gastroenterology 11 : 6549 6553.
31. Jansson, H., Hamberg, K., De Bruyn, H. Bratthall, G. (2005) Clinical consequences of IL-1 genotype on early implant failures in patients under periodontal maintenance. Clinical Implant Dentistry and Related Research 7 : 51 59.
32. Lachmann, S., Kimmerle-Muller, E., Axmann, D., Scheideler, L., Weber, H. Haas, R. (2007) Associations between peri-implant crevicular fluid volume, concentrations of crevicular inflammatory mediators, and composite IL-1A -889 and IL-1B +3954 genotype. A cross-sectional study on implant recall patients with and without clinical signs of peri-implantitis. Clinical Oral Implants Research 18 : 212 223.
33. Laine, M.L., Leonhardt, A., Roos-Jansaker, A.M., Pena, A.S., van Winkelhoff, A.J., Winkel, E.G. Renvert, S. (2006) IL-1RN gene polymorphism is associated with peri-implantitis. Clinical Oral Implants Research 17 : 380 385.
34. Lekholm, U., Gunne, J., Henry, P., Higuchi, K., Linden, U., Bergstrom, C. van Steenberghe, D. (1999) Survival of the Branemark implant in partially edentulous jaws: a 10-year prospective multicenter study. The International Journal of Oral & Maxillofacial Implants 14 : 639 645.
35. Lennard, A.C. (1995) Interleukin-1 receptor antagonist. Critical Reviews in Immunology 15 : 77 105.
36. Loe, H. Silness, J. (1963) Periodontal disease in pregnancy. 1. Prevalence and severity. Acta Odontologica Scandinavica 21 : 533 551.
37. Machtei, E.E., Oved-Peleg, E. Peled, M. (2006) Comparison of clinical, radiographic and immunological parameters of teeth and different dental implant platforms. Clinical Oral Implants Research 17 : 658 665.
38. Montes, C.C., Alvim-Pereira, F., Thome, G., Alves, E.D., Acedo, R.V., de Souza, J.R., Melo, A.C. Trevilatto, P.C. (2007) Failing factors associated with osseointegrated dental implant loss. Implant Dentistry 16 : 404 412.
39. Moreira, P.R., de Sa, A.R., Xavier, G.M., Costa, J.E., Gomez, R.S., Gollob, K.J. Dutra, W.O. (2005) A functional interleukin-1 beta gene polymorphism is associated with chronic periodontitis in a sample of Brazilian individuals. Journal of Periodontal Research 40 : 306 311.
40. Nicklin, M.J., Weith, A. Duff, G.W. (1994) A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes. Genomics 19 : 382 384.
41. Niimi, T., Sato, S., Tomita, H., Yamada, Y., Akita, K., Maeda, H., Kawaguchi, H., Sugiura, Y. Ueda, R. (2000) Lack of association with interleukin 1 receptor antagonist and interleukin-1beta gene polymorphisms in sarcoidosis patients. Respiratory Medicine 94 : 1038 1042.
42. Panagakos, F.S., Aboyoussef, H., Dondero, R. Jandinski, J.J. (1996) Detection and measurement of inflammatory cytokines in implant crevicular fluid: a pilot study. International Journal of Oral & Maxillofacial Implants 11 : 794 799.
43. Parfitt, A.M. (1994) Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. Journal of Cellular Biochemistry 55 : 273 286.
44. Parra, F.C., Amado, R.C., Lambertucci, J.R., Rocha, J., Antunes, C.M. Pena, S.D. (2003) Color and genomic ancestry in Brazilians. Proceedings of the National Academy of Sciences of the United States of America 100 : 177 182.
45. Perala, D.G., Chapman, R.J., Gelfand, J.A., Callahan, M.V., Adams, D.F. Lie, T. (1992) Relative production of IL-1 beta and TNF alpha by mononuclear cells after exposure to dental implants. Journal of Periodontology 63 : 426 430.
46. Piattelli, A., Scarano, A., Favero, L., Iezzi, G., Petrone, G. Favero, G.A. (2003) Clinical and histologic aspects of dental implants removed due to mobility. Journal of Periodontology 74 : 385 390.
47. Pociot, F., Molvig, J., Wogensen, L., Worsaae, H. Nerup, J. (1992) A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretion in vitro. European Journal of Clinical Investigation 22 : 396 402.
48. Porter, J.A. von Fraunhofer, J.A. (2005) Success or failure of dental implants? A literature review with treatment considerations. General Dentistry 53 : 423 432 quiz 433-446.
49. Roberts, F.A., McCaffery, K.A. Michalek, S.M. (1997) Profile of cytokine mRNA expression in chronic adult periodontitis. Journal of Dental Research 76 : 1833 1839.
50. Rogers, M.A., Figliomeni, L., Baluchova, K., Tan, A.E., Davies, G., Henry, P.J. Price, P. (2002) Do interleukin-1 polymorphisms predict the development of periodontitis or the success of dental implants? Journal of Periodontal Research 37 : 37 41.
51. Ruhling, A., Jepsen, S., Kocher, T. Plagmann, H.C. (1999) Longitudinal evaluation of aspartate aminotransferase in the crevicular fluid of implants with bone loss and signs of progressive disease. International Journal of Oral & Maxillofacial Implants 14 : 428 435.
52. Salcetti, J.M., Moriarty, J.D., Cooper, L.F., Smith, F.W., Collins, J.G., Socransky, S.S. Offenbacher, S. (1997) The clinical, microbial, and host response characteristics of the failing implant. International Journal of Oral & Maxillofacial Implants 12 : 32 42.
53. Santos, M.C., Campos, M.I. Line, S.R. (2002) Early dental implant failure: a review of the literature. Brazilian Journal Oral for Sciences 1 : 103 111.
54. Santtila, S., Savinainen, K. Hurme, M. (1998) Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1beta production in vitro. Scandinavian Journal of Immunology 47 : 195 198.
55. Scapoli, C., Trombelli, L., Mamolini, E. Collins, A. (2005) Linkage disequilibrium analysis of case-control data: an application to generalized aggressive periodontitis. Genes and Immunity 6 : 44 52.
56. Seymour, G.J., Gemmell, E., Lenz, L.J., Henry, P., Bower, R. Yamazaki, K. (1989) Immunohistologic analysis of the inflammatory infiltrates associated with osseointegrated implants. International Journal of Oral & Maxillofacial Implants 4 : 191 198.
57. Shimpuku, H., Nosaka, Y., Kawamura, T., Tachi, Y., Shinohara, M. Ohura, K. (2003) Genetic polymorphisms of the interleukin-1 gene and early marginal bone loss around endosseous dental implants. Clinical Oral Implants Research 14 : 423 429.
58. Silness, J. Loe, H. (1964) Periodontal disease in pregnancy. 2. Correlation between oral hygiene and periodontal condition. Acta Odontologica Scandinavica 22 : 121 135.
59. Strietzel, F.P., Reichart, P.A., Kale, A., Kulkarni, M., Wegner, B. Kuchler, I. (2007) Smoking interferes with the prognosis of dental implant treatment: a systematic review and meta-analysis. Journal of Clinical Periodontology 34 : 523 544.
60. Tatakis, D.N. (1993) Interleukin-1 and bone metabolism: a review. Journal of Periodontology 64 : 416 431.
61. Teronen, O., Konttinen, Y.T., Lindqvist, C., Salo, T., Ingman, T., Lauhio, A., Ding, Y., Santavirta, S. Sorsa, T. (1997) Human neutrophil collagenase MMP-8 in peri-implant sulcus fluid and its inhibition by clodronate. Journal of Dental Research 76 : 1529 1537.
62. Tolusso, B., Pietrapertosa, D., Morelli, A., De Santis, M., Gremese, E., Farina, G., Carniello, S.G., Del Frate, M. Ferraccioli, G. (2006) IL-1B and IL-1RN gene polymorphisms in rheumatoid arthritis: relationship with protein plasma levels and response to therapy. Pharmacogenomics 7 : 683 695.
63. Tountas, N.A., Casini-Raggi, V., Yang, H., Di Giovine, F.S., Vecchi, M., Kam, L., Melani, L., Pizarro, T.T., Rotter, J.I. Cominelli, F. (1999) Functional and ethnic association of allele 2 of the interleukin-1 receptor antagonist gene in ulcerative colitis. Gastroenterology 117 : 806 813.
64. Trevilatto, P.C. Line, S.R. (2000) Use of buccal epithelial cells for PCR amplification of large DNA fragments. Journal of Forensic Odonto-stomatology 18 : 6 9.
65. Trevilatto, P.C., Scarel-Caminaga, R.M., de Brito, R.B. Jr., de Souza, A.P. Line, S.R. (2003) Polymorphism at position -174 of IL-6 gene is associated with susceptibility to chronic periodontitis in a Caucasian Brazilian population. Journal of Clinical Periodontology 30 : 438 442.
66. Venter, J.C., Adams, M.D., Myers, E.W., Li, P.W., Mural, R.J., Sutton, G.G., Smith, H.O., Yandell, M., Evans, C.A., Holt, R.A., Gocayne, J.D., Amanatides, P., Ballew, R.M., Huson, D.H., Wortman, J.R., Zhang, Q., Kodira, C.D., Zheng, X.H., Chen, L., Skupski, M., Subramanian, G., Thomas, P.D., Zhang, J., Gabor Miklos, G.L., Nelson, C., Broder, S., Clark, A.G., Nadeau, J., McKusick, V.A., Zinder, N., Levine, A.J., Roberts, R.J., Simon, M., Slayman, C., Hunkapiller, M., Bolanos, R., Delcher, A., Dew, I., Fasulo, D., Flanigan, M., Florea, L., Halpern, A., Hannenhalli, S., Kravitz, S., Levy, S., Mobarry, C., Reinert, K., Remington, K., Abu-Threideh, J., Beasley, E., Biddick, K., Bonazzi, V., Brandon, R., Cargill, M., Chandramouliswaran, I., Charlab, R., Chaturvedi, K., Deng, Z., Di Francesco, V., Dunn, P., Eilbeck, K., Evangelista, C., Gabrielian, A.E., Gan, W., Ge, W., Gong, F., Gu, Z., Guan, P., Heiman, T.J., Higgins, M.E., Ji, R.R., Ke, Z., Ketchum, K.A., Lai, Z., Lei, Y., Li, Z., Li, J., Liang, Y., Lin, X., Lu, F., Merkulov, G.V., Milshina, N., Moore, H.M., Naik, A.K., Narayan, V.A., Neelam, B., Nusskern, D., Rusch, D.B., Salzberg, S., Shao, W., Shue, B., Sun, J., Wang, Z., Wang, A., Wang, X., Wang, J., Wei, M., Wides, R., Xiao, C., Yan, C., Yao, A., Ye, J., Zhan, M., Zhang, W., Zhang, H., Zhao, Q., Zheng, L., Zhong, F., Zhong, W., Zhu, S., Zhao, S., Gilbert, D., Baumhueter, S., Spier, G., Carter, C., Cravchik, A., Woodage, T., Ali, F., An, H., Awe, A., Baldwin, D., Baden, H., Barnstead, M., Barrow, I., Beeson, K., Busam, D., Carver, A., Center, A., Cheng, M.L., Curry, L., Danaher, S., Davenport, L., Desilets, R., Dietz, S., Dodson, K., Doup, L., Ferriera, S., Garg, N., Gluecksmann, A., Hart, B., Haynes, J., Haynes, C., Heiner, C., Hladun, S., Hostin, D., Houck, J., Howland, T., Ibegwam, C., Johnson, J., Kalush, F., Kline, L., Koduru, S., Love, A., Mann, F., May, D., McCawley, S., McIntosh, T., McMullen, I., Moy, M., Moy, L., Murphy, B., Nelson, K., Pfannkoch, C., Pratts, E., Puri, V., Qureshi, H., Reardon, M., Rodriguez, R., Rogers, Y.H., Romblad, D., Ruhfel, B., Scott, R., Sitter, C., Smallwood, M., Stewart, E., Strong, R., Suh, E., Thomas, R., Tint, N.N., Tse, S., Vech, C., Wang, G., Wetter, J., Williams, S., Williams, M., Windsor, S., Winn-Deen, E., Wolfe, K., Zaveri, J., Zaveri, K., Abril, J.F., Guigo, R., Campbell, M.J., Sjolander, K.V., Karlak, B., Kejariwal, A., Mi, H., Lazareva, B., Hatton, T., Narechania, A., Diemer, K., Muruganujan, A., Guo, N., Sato, S., Bafna, V., Istrail, S., Lippert, R., Schwartz, R., Walenz, B., Yooseph, S., Allen, D., Basu, A., Baxendale, J., Blick, L., Caminha, M., Carnes-Stine, J., Caulk, P., Chiang, Y.H., Coyne, M., Dahlke, C., Mays, A., Dombroski, M., Donnelly, M., Ely, D., Esparham, S., Fosler, C., Gire, H., Glanowski, S., Glasser, K., Glodek, A., Gorokhov, M., Graham, K., Gropman, B., Harris, M., Heil, J., Henderson, S., Hoover, J., Jennings, D., Jordan, C., Jordan, J., Kasha, J., Kagan, L., Kraft, C., Levitsky, A., Lewis, M., Liu, X., Lopez, J., Ma, D., Majoros, W., McDaniel, J., Murphy, S., Newman, M., Nguyen, T., Nguyen, N., Nodell, M., Pan, S., Peck, J., Peterson, M., Rowe, W., Sanders, R., Scott, J., Simpson, M., Smith, T., Sprague, A., Stockwell, T., Turner, R., Venter, E., Wang, M., Wen, M., Wu, D., Wu, M., Xia, A., Zandieh, A. Zhu, X. (2001) The sequence of the human genome. Science 291 : 1304 1351.
67. Weyant, R.J. Burt, B.A. (1993) An assessment of survival rates and within-patient clustering of failures for endosseous oral implants. Journal of Dental Research 72 : 2 8.
68. Wilson, T.G. Jr. Nunn, M. (1999) The relationship between the interleukin-1 periodontal genotype and implant loss. Initial data. Journal of Periodontology 70 : 724 729.