Histopathologic Observations on Early Oral Implant Failures

International Journal of Oral and Maxillofacial Implants

Volumn 14, Issue 6, 1999, Pages 798-810

  Esposito, Marco ^a   Thomsen, Peter ^a   Ericson, Lars E ^a   Lekholm, Ulf ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Dental implant; Early failures; Morphology; Titanium; Ultrastructure

Indexed keywords

ADULT; AGED; ARTICLE; BONE REGENERATION; DENTAL SURGERY; DESMOSOME; FEMALE; HUMAN; INFECTION; MALE; MIDDLE AGED; OSTEOLYSIS; PATHOLOGY; PERIODONTITIS; PERIODONTIUM; SURGICAL INFECTION; TOOTH IMPLANTATION; WOUND DEHISCENCE;

ADULT; AGED; ALVEOLAR BONE LOSS; DENTAL IMPLANTATION, ENDOSSEOUS; DENTAL IMPLANTS; DENTAL RESTORATION FAILURE; DESMOSOMES; FEMALE; HUMANS; MALE; MIDDLE AGED; OSSEOINTEGRATION; PERIODONTITIS; PERIODONTIUM; PROSTHESIS-RELATED INFECTIONS; SURGICAL WOUND DEHISCENCE; SURGICAL WOUND INFECTION;

EID: 0033216801     PISSN: 08822786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Albrektsson T, Brånemark P-I, Hansson H-A, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand 1981;52:155-170.
2. Lekholm U, van Steenberghe D, Herrmann I, Bolender C, Folmer T, Gunne J, et al. Osseointegrated implants in the treatment of partially edentulous jaws: A prospective 5-year multicenter study. Int J Oral Maxillofac Implants 1994;9:627-635.
3. Jemt T, Chai J, Harnet J, Heath MR, Hutton JE, Johns RB, et al. A 5-year prospective multicenter follow-up report on overdentures supported by Osseointegrated implants. Int J Oral Maxillofac Implants 1996;11:291-298.
4. Henry PJ, Laney WR, Jemt T, Harris D, Krogh PHJ, Polizzi G, et al. Osseointegrated implants for single-tooth replacement: A prospective 5-year multicenter study. Int J Oral Maxillofac Implants 1996;11:450-455.
5. Friberg B, Nilson H, Olsson M, Palmquist C. Mark II: The self-tapping Brånemark implant: 5-year results of a prospective 3-center study. Clin Oral Implants Res 1997;8: 279-285.
6. Esposito M, Hirsch J-M, Lekholm U, Thomsen P. Biological factors contributing to failures of osseointegrated oral implants. (I) Success criteria and epidemiology. Eur J Oral Sci 1998;106:527-551.
7. Esposito M, Hirsch J-M, Lekholm U, Thomsen P. Biological factors contributing to failures of osseointegrated oral implants. (II) Etiopathogenesis. Eur J Oral Sci 1998;106: 721-764.
8. Friberg B, Jemt T, Lekholm U. Early failures in 4,641 consecutively placed Brånemark dental implants: A study from stage 1 surgery to the connection of completed prostheses. Int J Oral Maxillofac Implants 1991;6:142-146.
9. Brånemark P-I, Breine U, Adell R, Hansson BO, Lindström J, Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg 1969; 3:81-100.
10. Meenaghan MA, Natiella JR, Armitage JE, Greene GWJ, Lipani CS. The crypt surface of blade-vent implants in clinical failure: An electron microscopic study. J Prosthet Dent 1974;31:681-690.
11. Brunski JB, Moccia AFJ, Pollack SR, Korostoff E, Trachtenberg DI. The influence of functional use of endosseous dental implants on the tissue-implant interface. I. Histological aspects. J Dent Res 1979;58:1953-1969.
12. Takeshita F, Kuroki H, Yamasaki A, Suetsugu T. Histopathologic observation of seven removed endosseous dental implants. Int J Oral Maxillofac Implants 1995;10: 367-372.
13. Takeshita F, Suetsugu T, Higuchi Y, Oishi M. Histologic study of failed hollow implants. Int J Oral Maxillofac Implants 1996;11:245-250.
14. Piattelli A, Scarano A, Piattelli M. Microscopical aspects of failure in osseointegrated dental implants: A report of five cases. Biomaterials 1996;17:1235-1241.
15. Takeshita F, Iyama S, Ayukawa Y, Suetsugu T, Oishi M. Abscess formation around a hydroxyapatite-coated implant placed into the extraction socket with autogenous bone graft. A histological study using light microscopy, image processing, and confocal laser scanning microscopy. J Periodontol 1997;68:299-305.
16. Piattelli A, Scarano A, Piattelli M, Podda G. Implant periapical lesions: Clinical, histologic, and histochemical aspects. A case report. Int J Periodontics Restorative Dent 1998;18:181-187.
17. Piattelli A, Piattelli M, Mangano C, Scarano A. A histologic evaluation of eight cases of failed dental implants: Is bone overheating the most probable cause? Biomaterials 1998;19:683-690.
18. Piattelli A, Scarano A, Dalla Nora A, De Bona G, Favero GA. Microscopical features in retrieved human Brånemark implants: A report of 19 cases. Biomaterials 1998;19: 643-649.
19. Esposito M, Hirsch J-M, Lekholm U, Thomsen P. Failure patterns of four osseointegrated oral implant systems. J Mater Sci Mater Med 1997;8:843-847.
20. Truhlar RS, Farish SE, Scheitler LE, Morris HF, Ochi S. Bone quality and implant design-related outcomes through stage II surgical uncovering of Spectra System root form implants. J Oral Maxillofac Surg 1997;55(suppl 5):46-54.
21. Dent CD, Olson JW, Farish SE, Bellome J, Casino AJ, Morris HF, Ochi S. The influence of preoperative antibiotics on success of endosseous implants up to and including stage II surgery: A study of 2,641 implants. J Oral Maxillofac Surg 1997;55(suppl 5):19-24.
22. Morris HF, Manz MC, Tarolli JH. Success of multiple endosseous dental implant designs to second-stage surgery across study sites. J Oral Maxillofac Surg 1997;55 (suppl 5):76-82.
23. Lambert PM, Morris HF, Ochi S. Positive effect of surgical experience with implants on second-stage implant survival. J Oral Maxillofac Surg 1997;55(suppl 5):12-18.
24. Lekholm U, Zarb GA. Patient selection and preparation. In: Brånemark P-I, Zarb GA, Albrektsson T (eds). Tissue-Integrated Prostheses. Chicago: Quintessence, 1985: 199-209.
25. Adell R, Lekholm U, Brånemark P-I. Surgical procedures. In: Brånemark P-I, Zarb GA, Albrektsson T (eds). Tissue-Integrated Prostheses. Chicago: Quintessence, 1985: 211-232.
26. Esposito M. Thomsen P, Mölne J, Gretzer C, Ericson LE, Lekholm U. Immunohistochemistry of soft tissues surrounding late failures of Brånemark implants. Clin Oral Implants Res 1997;8:352-366.
27. Bjursten LM, Emanuelsson L, Ericson LE, Thomsen P, Lausmaa J, Mattson L, et al. A new method for ultrastructural studies of the intact tissue-metal interface. Biomaterials 1990;11:569-601.
28. Donath K, Breuner G. A method for the study of undecalcified bones and teeth with attached soft tissues. The Sage-Schliff (sawing and grinding) technique. J Oral Pathol 1982;11:318-326.
29. Thomsen P, Ericson LE. Light and transmission electron microscopy used to study the tissue morphology close to implants. Biomaterials 1985;6:421-424.
30. Dougherty SH, Simmons RL. Infections in bionic man: The pathobiology of infections in prosthetic devices - Part II. Curr Probl Surg 1982;19:269-318.
31. Nishioka GJ, Jones J, Triplett RG, Aufdemorte TB. The role of bacterial-laden biofilms in infections of maxillofacial biomaterials. J Oral Maxillofac Surg 1988;46:19-25.
32. Van Steenberghe D, Lekholm U, Bolender C, Folmer T, Henry P, Herrmann I, et al. The applicability of osseointegrated oral implants in the rehabilitation of partial edentulism: A prospective multicenter study on 558 fixtures. Int J Oral Maxillofac Implants 1990,5:272-281.
33. Quirynen M, Naert I, van Steenberghe D, Dekeyser C, Callens A. Periodontal aspects of osseointegrated fixtures supporting a partial bridge. An up to 6-years retrospective study. J Clin Periodontol 1992;19:118-126.
34. Lambert PM, Morris HF, Ochi S. The influence of 0.12% chlorhexidine digluconate rinses on the incidence of infectious complications and implant success. J Oral Maxillofac Surg 1997;55(suppl 5):25-30.
35. Sussman HI, Moss SS. Localized osteomyelitis secondary to endodontic-implant pathosis. A case report. J Periodontol 1993;64:306-310.
36. Isidor F. Mobility assessment with the Periotest system in relation to histologic findings of oral implants. Int J Oral Maxillofac Implants 1998;13:377-383.
37. Aspenberg P, Herbertsson P. Periprosthetic bone resorption. J Bone Joint Surg [Br] 1996;78:641-646.
38. Eriksson AS, Bjursten LM, Ericson LE, Thomsen P. Hollow implants in soft tissues allowing quantitative studies of cells and fluid at the implant interface. Biomaterials 1988; 9:86-90.
39. Ericson LE, Johansson BR, Rosengren A, Sennerby L, Thomsen P. Ultrastructural investigation and analysis of the interface of retrieved metal implants. In: Davies JE (ed). The Bone-Biomaterial Interface. Toronto: Univ of Toronto Press, 1991:425-437.
40. Cameron HU, Pilliar RM, Macnab I. The effect of movement on the bonding of porous metal to bone. J Biomed Mater Res 1973;7:301-311.
41. Aspenberg P, Goodman S, Toksvig-Larsen S, Ryd L, Albrektsson T. Intermittent micromotion inhibits bone ingrowth. Titanium implants in rabbits. Acta Orthop Scand 1992;63:141-145.
42. Goodman S, Wang J-S, Doshi A, Aspenberg P. Difference in bone ingrowth after one versus two daily episodes of micromotion: Experiments with titanium chambers in rabbits. J Biomed Mater Res 1993;27:1419-1424.
43. Takata T, Miyauchi M, Ogawa I, Ito H, Kobayashi J, Nikai H. Reactive change in proliferative activity of the junctional epithelium after topical application of lipopolysaccharide. J Periodontol 1997;68:531-535.
44. Ristow H-J. A major factor contributing to epidermal proliferation in inflammatory skin diseases appears to be interleukin-1 or a related protein. Proc Natl Acad Sci USA 1987;84:1940-1944.
45. Lee SW, Morhenn VB, Ilnicka M, Eugui EM, Allison AC. Autocrine stimulation of interleukin-1 alpha and transforming growth factor alpha production in human keratinocytes and its antagonism by glucocorticoids. J Invest Dermatol 1991;97:106-110.
46. Jansen JA, de Groot K. Guinea pig and rabbit model for the histological evaluation of permanent percutaneous implants. Biomaterials 1988;9:268-272.
47. Petty W, Spanier S, Shuster JJ, Silverthrone C. The influence of skeletal implants on incidence of infection. J Bone Joint Surg [Am] 1985;67:1236-1244.
48. Gould TRL, Westbury L, Brunette DM. Ultrastructural study of the attachment of human gingiva to titanium in vivo. J Prosthet Dent 1984;52:418-420.
49. Engquist B, Nilson H, Åstrand P. Single-tooth replacement by osseointegrated Brånemark implants. A retrospective study of 82 implants. Clin Oral Implants Res 1995;6: 238-245.
50. Ivanoff C-J, Sennerby L, Lekholm U. Reintegration of mobilized titanium implants. An experimental study in rabbit tibia. Int J Oral Maxillofac Surg 1997;26:310-315.
51. Nyström E, Kahnberg K-E, Albrektsson T. Treatment of the severely resorbed maxillae with bone graft and titanium implants: Histologic review of autopsy specimens. Int J Oral Maxillofac Implants 1993;8:167-172.