-
1
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993 ; 75 : 843-54.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
2
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005 ; 120 : 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
3
-
-
0347444723
-
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004 ; 116 : 281-97.
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004 ; 116 : 281-97.
-
-
-
-
4
-
-
37648998629
-
Getting to the root of miRNA-mediated gene silencing
-
Eulalio A, Huntzinger E, Izaurralde E. Getting to the root of miRNA-mediated gene silencing. Cell 2008 ; 132 : 9-14.
-
(2008)
Cell
, vol.132
, pp. 9-14
-
-
Eulalio, A.1
Huntzinger, E.2
Izaurralde, E.3
-
5
-
-
36749026906
-
Switching from repression to activation: MicroRNAs can up-regulate translation
-
Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science 2007 ; 318 : 1931-4.
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
6
-
-
43449090367
-
MicroRNA-10a binds the 5′UTR of ribosomol protein mRNAs and enhances their translation
-
Ørom UA, Nielsen FC, Lund AH. MicroRNA-10a binds the 5′UTR of ribosomol protein mRNAs and enhances their translation. Mol Cell 2008 ; 30 : 460-71.
-
(2008)
Mol Cell
, vol.30
, pp. 460-471
-
-
Ørom, U.A.1
Nielsen, F.C.2
Lund, A.H.3
-
7
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006 ; 6 : 857-66.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
8
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004 ; 101 : 2999-3004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
-
9
-
-
20444467290
-
A microRNA polycistron as a potential human oncogene
-
He L, Thomson JM, Hemann MT, et al. A microRNA polycistron as a potential human oncogene. Nature 2005 ; 435 : 828-33.
-
(2005)
Nature
, vol.435
, pp. 828-833
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
-
10
-
-
2342450524
-
Molecular evolution of a microRNA cluster
-
Tanzer A, Stadler PF. Molecular evolution of a microRNA cluster. J Mol Biol 2004 ; 339 : 327-35.
-
(2004)
J Mol Biol
, vol.339
, pp. 327-335
-
-
Tanzer, A.1
Stadler, P.F.2
-
11
-
-
41949102707
-
-
Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell 2008 ; 133 : 217-22.
-
Mendell JT. miRiad roles for the miR-17-92 cluster in development and disease. Cell 2008 ; 133 : 217-22.
-
-
-
-
12
-
-
39749143354
-
Targeted deletion reveals essential and overlapping functions of the miR-17-92 family of miRNA clusters
-
Ventura A, Young AG, Winslow MM, et al. Targeted deletion reveals essential and overlapping functions of the miR-17-92 family of miRNA clusters. Cell 2008 ; 132 : 875-86.
-
(2008)
Cell
, vol.132
, pp. 875-886
-
-
Ventura, A.1
Young, A.G.2
Winslow, M.M.3
-
13
-
-
39749163245
-
Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes
-
Xiao C, Srinivasan L, Calado DP, et al. Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 2008 ; 9 : 405-14.
-
(2008)
Nat Immunol
, vol.9
, pp. 405-414
-
-
Xiao, C.1
Srinivasan, L.2
Calado, D.P.3
-
14
-
-
27544495514
-
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
-
Hayashita Y, Osada H, Tatematsu Y, et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005 ; 65 : 9628-32.
-
(2005)
Cancer Res
, vol.65
, pp. 9628-9632
-
-
Hayashita, Y.1
Osada, H.2
Tatematsu, Y.3
-
15
-
-
2342449399
-
Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
-
Ota A, Tagawa H, Karnan S, et al. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res 2004 ; 64 : 3087-95.
-
(2004)
Cancer Res
, vol.64
, pp. 3087-3095
-
-
Ota, A.1
Tagawa, H.2
Karnan, S.3
-
16
-
-
34748900267
-
Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells
-
Lu Y, Thomson JM, Wong HYF, et al. Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol 2007 ; 310 : 442-53.
-
(2007)
Dev Biol
, vol.310
, pp. 442-453
-
-
Lu, Y.1
Thomson, J.M.2
Wong, H.Y.F.3
-
17
-
-
20444479428
-
c-Myc-regulated microRNAs modulate E2F1 expression
-
O'Donnell KA, Wentzel EA, Zeller KI, et al. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005 ; 435 : 839-43.
-
(2005)
Nature
, vol.435
, pp. 839-843
-
-
O'Donnell, K.A.1
Wentzel, E.A.2
Zeller, K.I.3
-
18
-
-
34047267329
-
An E2F/miR-20a autoregulatory feedback loop
-
Sylvestre Y, De Guire V, Querido E, et al. An E2F/miR-20a autoregulatory feedback loop. J Biol Chem 2007 ; 282 : 2135-43.
-
(2007)
J Biol Chem
, vol.282
, pp. 2135-2143
-
-
Sylvestre, Y.1
De Guire, V.2
Querido, E.3
-
19
-
-
34047264639
-
Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
-
Woods K, Thomson JM, Hammond SM. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 2007 ; 282 : 2130-4.
-
(2007)
J Biol Chem
, vol.282
, pp. 2130-2134
-
-
Woods, K.1
Thomson, J.M.2
Hammond, S.M.3
-
20
-
-
39849095077
-
E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer
-
Petrocca F, Visone R, Onelli MR, et al. E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 2008 ; 13 : 272-86.
-
(2008)
Cancer Cell
, vol.13
, pp. 272-286
-
-
Petrocca, F.1
Visone, R.2
Onelli, M.R.3
-
21
-
-
42949093218
-
miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130
-
Wang Q, Li YC, Wang J, et al. miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130. Proc Natl Acad Sci USA 2008 ; 105 : 2889-94.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2889-2894
-
-
Wang, Q.1
Li, Y.C.2
Wang, J.3
-
22
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997 ; 275 : 1943-7.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
-
23
-
-
34447101200
-
Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92
-
Matsubara H, Takeuchi T, Nishikawa E, et al. Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92. Oncogene 2007 ; 26 : 6099-105.
-
(2007)
Oncogene
, vol.26
, pp. 6099-6105
-
-
Matsubara, H.1
Takeuchi, T.2
Nishikawa, E.3
-
24
-
-
39749101294
-
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage
-
Koralov SB, Muljo SA, Galler GR, et al. Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage. Cell 2008 ; 132 : 860-74.
-
(2008)
Cell
, vol.132
, pp. 860-874
-
-
Koralov, S.B.1
Muljo, S.A.2
Galler, G.R.3
-
25
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet P, Metcalf D, Huang DC, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999 ; 286 : 1735-8.
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.3
-
27
-
-
33745168962
-
microRNAs exhibit high frequency genomic alterations in human cancer
-
Zhang L, Huang J, Yang N, et al. microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci USA 2006 ; 103 : 9136-41.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 9136-9141
-
-
Zhang, L.1
Huang, J.2
Yang, N.3
-
28
-
-
33750376591
-
Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AlB1 mRNA
-
Hossain A, Kuo MT, Saunders GF. Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AlB1 mRNA. Mol Cell Biol 2006 ; 26 : 8191-201.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8191-8201
-
-
Hossain, A.1
Kuo, M.T.2
Saunders, G.F.3
-
29
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, et al. RAS is regulated by the let-7 microRNA family. Cell 2005 ; 120 : 635-47.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
-
30
-
-
0034597777
-
Conservation of the sequence and temporal expression of let-7 heterochrony regulatory RNA
-
Pasquinelli AE, Reinhart BJ, Slack F, et al. Conservation of the sequence and temporal expression of let-7 heterochrony regulatory RNA. Nature 2000 ; 408 : 86-9.
-
(2000)
Nature
, vol.408
, pp. 86-89
-
-
Pasquinelli, A.E.1
Reinhart, B.J.2
Slack, F.3
-
31
-
-
2542626605
-
Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
-
Takamizawa J, Konishi H, Yanagisawa K, et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004 ; 64 : 3753-6.
-
(2004)
Cancer Res
, vol.64
, pp. 3753-3756
-
-
Takamizawa, J.1
Konishi, H.2
Yanagisawa, K.3
-
32
-
-
34548012848
-
The let-7 microRNA represses cell proliferation pathways in human cells
-
Johnson CD, Esquela-Kerscher A, Stefani G, et al. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res 2007 ; 67 : 7713-22.
-
(2007)
Cancer Res
, vol.67
, pp. 7713-7722
-
-
Johnson, C.D.1
Esquela-Kerscher, A.2
Stefani, G.3
-
33
-
-
4444288119
-
Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer
-
Sgarra R, Rustighi A, Tessari MA, et al. Nuclear phosphoproteins HMGA and their relationship with chromatin structure and cancer. FEBS Lett 2004 ; 574 : 1-8.
-
(2004)
FEBS Lett
, vol.574
, pp. 1-8
-
-
Sgarra, R.1
Rustighi, A.2
Tessari, M.A.3
-
34
-
-
34247565615
-
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
-
Lee YS, Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 2007 ; 21 : 1025-30.
-
(2007)
Genes Dev
, vol.21
, pp. 1025-1030
-
-
Lee, Y.S.1
Dutta, A.2
-
35
-
-
33947431322
-
Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
-
Mayr C, Hemann MT, Bartel DP. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 2007 ; 315 : 1576-9.
-
(2007)
Science
, vol.315
, pp. 1576-1579
-
-
Mayr, C.1
Hemann, M.T.2
Bartel, D.P.3
-
36
-
-
35449003175
-
MicroRNA Let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma Cells
-
Sampson VB, Rong NH, Han J, et al. MicroRNA Let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma Cells. Cancer Res 2007 ; 67 : 9762-70.
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
-
37
-
-
37549008310
-
Widespread microRNA repression by Myc contributes to tumorigenesis
-
Chang TC, Yu D, Lee YS, et al. Widespread microRNA repression by Myc contributes to tumorigenesis. Nat Genet 2008 ; 40 : 43-50.
-
(2008)
Nat Genet
, vol.40
, pp. 43-50
-
-
Chang, T.C.1
Yu, D.2
Lee, Y.S.3
-
38
-
-
41649114199
-
Suppression of non-small cell lung tumor development by the let-7 microRNA family
-
Kumar MS, Erkeland SJ, Pester RE, et al. Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci USA 2008 ; 105 : 3903-8.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3903-3908
-
-
Kumar, M.S.1
Erkeland, S.J.2
Pester, R.E.3
-
39
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006 ; 103 : 2257-61.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
-
40
-
-
36849078711
-
let-7 regulates self renewal and tumongenicity of breast cancer cells
-
Yu F, Yao H, Zhu P, et al. let-7 regulates self renewal and tumongenicity of breast cancer cells. Cell 2007 ; 131 : 1109-23.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
|