TGF-α expression as a potential biomarker of risk within the normal-appearing colorectal mucosa of patients with and without incident sporadic adenoma

Cancer Epidemiology Biomarkers and Prevention

Volumn 18, Issue 1, 2009, Pages 65-73

  Daniel, Carrie R ^a   Bostick, Roberd M ^a,c   Flanders, William Dana ^a   Long, Qi ^a   Fedirko, Veronika ^a   Sidelnikov, Eduard ^a   Seabrook, March E ^b  

^a EMORY UNIVERSITY   (United States)

^b Consultants in Gastroenterology ^*  (United States)

^c Department of Epidemiology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NONSTEROID ANTIINFLAMMATORY AGENT; TRANSFORMING GROWTH FACTOR ALPHA;

ADULT; AGED; ANAMNESIS; ARTICLE; CANCER INCIDENCE; CANCER RISK; CLINICAL ARTICLE; COLON BIOPSY; COLON MUCOSA; COLONOSCOPY; COLORECTAL ADENOMA; CONTROLLED STUDY; DIETARY INTAKE; FAMILY HISTORY; FEMALE; HORMONE SUBSTITUTION; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; LIFESTYLE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; QUESTIONNAIRE; RECTUM BIOPSY; RECTUM MUCOSA;

ADENOMA; ADULT; AGED; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; COLONOSCOPY; COLORECTAL NEOPLASMS; DIET; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INCIDENCE; INTESTINAL MUCOSA; MALE; MIDDLE AGED; PHENOTYPE; QUESTIONNAIRES; REGRESSION ANALYSIS; RISK FACTORS; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR MARKERS, BIOLOGICAL;

EID: 58349086769     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-08-0732     Document Type: Article

References (54)

1. Church J, Casey G. Molecular genetics and colorectal neoplasia. Kluwer Academic Publishers; 2004.
2. Srivastava S, Lippman SM, Hong WK, Mulshine JL, editors. Early detection of cancer: molecular markers. Armonk (NY): Futura Publishing Company, Inc.; 1994.
3. Schatzkin A, Gail M. The promise and peril of surrogate end points in cancer research. Nat Rev Cancer 2002;2:19-27.
4. Curry S, Byers T, Hewitt M, editors. Fulfilling the potential of cancer prevention and early detection. Institute of Medicine National Research Council. Washington (DC): National Academy of Sciences; 2003.
5. Branca F, Hanley AB, Pool-Zobel B, Verhagen H. Biomarkers in disease and health. Br J Nutr 2001;86 Suppl 1:S55-92.
6. Ponz de Leon M. Colorectal cancer. New York: Springer-Verlag Berlin Heidelberg; 2002.
7. Bostick RM, Fosdick L, Grandits GA, et al. Colorectal epithelial cell proliferative kinetics and risk factors for colon cancer in sporadic adenoma patients. Cancer Epidemiol Biomarkers Prev 1997;6:1011-9.
8. Cameron IL, Hardman WE. Paracrine action of transforming growth factor-α in rectal crypt epithelium of humans. Cell Biol Int 2002;26:1029-34.
9. Awwad RA, Sergina N, Yang H, et al. The role of transforming growth factor α in determining growth factor independence. Cancer Res 2003;63:4731-8.
10. Srivastava S, Henson DE, Gazdar AF. Molecular pathology of early cancer. Amsterdam: IOS Press; 1998.
11. Markowitz SD, Molkentin K, Gerbic C, Jackson J, Stellato T, Willson JK. Growth stimulation by coexpression of transforming growth factor-α and epidermal growth factor-receptor in normal and adenomatous human colon epithelium. J Clin Invest 1990;86:356-62.
12. Riese DJ, Kim ED, Elenius K, et al. The epidermal growth factor receptor couples transforming growth factor-α, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4. J Biol Chem 1996;271:20047-52.
13. Tanaka S, Imanishi K, Haruma K, et al. Immunoreactive transforming growth factor-α and epidermal growth factor in colorectal adenomas and carcinomas. Oncology 1992;49:381-5.
14. Herlyn M, Kath R, Williams N, Valyi-Nagy I, Rodeck U. Growth-regulatory factors for normal, premalignant, and malignant human cells in vitro. Adv Cancer Res 1990;54:213-34.
15. Wilcox JN, Derynck R. Localization of cells synthesizing transforming growth factor-α mRNA in the mouse brain. J Neurosci 1988;8:1901-4.
16. Lipkin M, Deschner E. Early proliferative changes in intestinal cells. Cancer Res 1976;36:2665-8.
17. Cameron IL, Hardman WE, Heitman DW, Carter JW. Dietary fibre on cell proliferation in large bowel mucosal crypts near or away from lymphoid nodules and on mineral bioavailability. Cell Prolif 2000;33:367-79.
18. Egger B, Carey HV, Procaccino F, et al. Reduced susceptibility of mice overexpressing transforming growth factor α to dextran sodium sulphate induced colitis. Gut 1998;43:64-70.
19. Chapkin RS, Davidson LA, Ly L, Weeks BR, Lupton JR, McMurray DN. Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancer. J Nutr 2007;137:200-4S.
20. Caderni G, Palli D, Lancioni L, et al. Dietary determinants of colorectal proliferation in the normal mucosa of subjects with previous colon adenomas. Cancer Epidemiol Biomarkers Prev 1999;8:219-25.
21. Cameron IL, Ord VA, Hunter KE, Van Nguyen M, Padilla GM, Heitman DW. Quantitative contribution of factors regulating rat colonic crypt epithelium: role of parenteral and enteral feeding, caloric intake, dietary cellulose level and the colon carcinogen DMH. Cell Tissue Kinet 1990;23:227-35.
22. Deschner EE, Lytle JS, Wong G, Ruperto JF, Newmark HL. The effect of dietary omega-3 fatty acids (fish oil) on azoxymethanol-induced focal areas of dysplasia and colon tumor incidence. Cancer 1990;66:2350-6.
23. Tanaka S, Imanishi K, Yoshihara M, et al. Immunoreactive transforming growth factor a is commonly present in colorectal neoplasia. Am J Pathol 1991;139:123-9.
24. Hardman WE, Cameron IL, Beer WH, Speeg KV, Kadakia SC, Lang KA. Transforming growth factor a distribution in rectal crypts as a biomarker of decreased colon cancer risk in patients consuming cellulose. Cancer Epidemiol Biomarkers Prev 1997;6:633-7.
25. Barnes CJ, Hamby-Mason RL, Hardman WE, Cameron IL, Speeg KV, Lee M. Effect of aspirin on prostaglandin E2 formation and transforming growth factor a expression in human rectal mucosa from individuals with a history of adenomatous polyps of the colon. Cancer Epidemiol Biomarkers Prev 1999;8:311-5.
26. Kushi L, Kaye S, Folsom A, Soler J, Prineas R. Accuracy and reliability of self-measurement of body girths. Am J Epidemiol 1988;128:740-8.
27. Pereira M, FitzerGerald SJ, Gregg EW, et al. A collection of physical activity questionnaires for health related research. Med Sci Sports Exerc 1997;29:S5-88.
28. Willett W, Sampson L, Stampfer MJ, et al. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 1985;122:51-65.
29. Willett W, Sampson L, Browne ML, et al. The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol 1988;127.
30. O'Brien M, Winawer S, Zauber A, et al.; The National Polyp Study Workgroup. The National Polyp Study: patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterology 1990;98:371-9.
31. Bostick RM, Kong KY, Ahearn TU, Chaudry Q, Cohen V, Wang MD. Detecting and quantifying biomarkers of risk for colorectal cancer using quantum dots and novel image analysis algorithms. Conf Proc IEEE Eng Med Biol Soc 2006;1:3313-6.
32. Willett W, Stampfer MJ. Total energy intake: implications for epidemiologic analyses. Am J Epidemiol 1986;124:17-27.
33. Neter J, Kutner M, Nachtsheim C, Wasserman W. Applied linear statistical models. Chicago: Times Mirror Higher Education Group, Inc.; 1996.
34. Akedo I, Ishikawa H, Ioka T, et al. Evaluation of epithelial cell proliferation rate in normal-appearing colonic mucosa as a high-risk marker for colorectal cancer. Cancer Epidemiol Biomarkers Prev 2001;10:925-30.
35. Bostick RM, Fosdick L, Wood JR, et al. Calcium and colorectal epithelial cell proliferation in sporadic adenoma patients: a randomized, double-blinded, placebo-controlled clinical trial. J Natl Cancer Inst 1995;87:1307-15.
36. Einspahr JG, Alberts DS, Gapstur SM, Bostick RM, Emerson SS, Gerner EW. Surrogate end-point biomarkers as measures of colon cancer risk and their use in cancer chemoprevention trials. Cancer Epidemiol Biomarkers Prev 1997;6:37-48.
37. Chen LC, Hao CY, Chiu YS, et al. Alteration of gene expression in normal-appearing colon mucosa of APC(min) mice and human cancer patients. Cancer Res 2004;64:3694-700.
38. Hao CY, Moore DH, Chiu YS, et al. Altered gene expression in normal colonic mucosa of individuals with polyps of the colon. Dis Colon Rectum 2005;48:2329-35.
39. Hao CY, Moore DH, Wong P, Bennington JL, Lee NM, Chen LC. Alteration of gene expression in macroscopically normal colonic mucosa from individuals with a family history of sporadic colon cancer. Clin Cancer Res 2005;11:1400-7.
40. Thomas DM, Nasim MM, Gullick WJ, Alison MR. Immunoreactivity of transforming growth factor α in the normal adult gastrointestinal tract. Gut 1992;33:628-31.
41. Lieberman DA, Prindiville S, Weiss DG, Willett W. Risk factors for advanced colonic neoplasia and hyperplastic polyps in asymptomatic individuals. JAMA 2003;290:2959-67.
42. Giovannucci E. Modifiable risk factors for colon cancer. Gastroenterol Clin North Am 2002;31:925-43.
43. Hawk ET, Levin B. Colorectal cancer prevention. J Clin Oncol 2005;23:378-91.
44. Caderni G, Luceri C, Lancioni L, Dolara P. Dietary sucrose, glucose, fructose, and starches affect colonic functions in rats. Nutr Cancer 1996;25:179-86.
45. Luceri C, Caderni G, Lancioni L, et al. Effects of repeated boluses of sucrose on proliferation and on AOM-induced aberrant crypt foci in rat colon. Nutr Cancer 1996;25:187-96.
46. Stamp D, Zhang XM, Medline A, Bruce WR, Archer MC. Sucrose enhancement of the early steps of colon carcinogenesis in mice. Carcinogenesis 1993;14:777-9.
47. Wang D, Patil S, Li W, Humphrey LE, Brattain MG, Howell GM. Activation of the TGFα autocrine loop is downstream of IGF-I receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells. Oncogene 2002;21:2785-96.
48. Yee YK, Chintalacharuvu SR, Lu J, Nagpal S. Vitamin D receptor modulators for inflammation and cancer. Mini Rev Med Chem 2005;5:761-78.
49. Arber N, Eagle CJ, Spicak J, et al.; the PreSAP Trial Investigators. Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med 2006;355:885-95.
50. Bertagnolli MM, Eagle CJ, Zauber AG, et al.; the APC Study Investigators. Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med 2006;355:873-84.
51. Baron JA, Cole BF, Mott L, et al. Neoplastic and antineoplastic effects of β-carotene on colorectal adenoma recurrence: results of a randomized trial. J Natl Cancer Inst 2003;95:717-22.
52. Weindruch R, Albanes D, Kritchevsky D. The role of calories and caloric restriction in carcinogenesis. Hematol Oncol Clin North Am 1991;5:79-89.
53. Albanes D, Salbe AD, Levander OA, Taylor PR, Nixon DW, Winick M. The effect of early caloric restriction on colonic cellular growth in rats. Nutr Cancer 1990;13:73-80.
54. Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med 2003;54:131-52.