The expression of cyclins D1 and E in predicting short-term survival in squamous cell carcinoma of the lung

Modern Pathology

Volumn 13, Issue 11, 2000, Pages 1167-1172

  Anton, Rose C ^a   Coffey, Donna M ^a   Gondo, Margaret M ^a   Stephenson, Mark A ^a   Brown, Richard W ^a   Cagle, Philip T ^a  

^a HOUSTON METHODIST HOSPITAL   (United States)

Author keywords

Cyclin D1; Cyclin E; Immunohistochemistry; Lung; Non small cell carcinoma; Prognostic factors

Indexed keywords

CYCLIN D1; CYCLIN E; TUMOR MARKER; BIOCHEMICAL MARKER;

ADULT; AGED; ARTICLE; CANCER STAGING; ENZYME IMMUNOASSAY; FEMALE; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL; SURVIVAL RATE; CANCER SURVIVAL; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DISEASE COURSE; DISEASE MARKER; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG SQUAMOUS CELL CARCINOMA; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CYCLIN D1; CYCLIN E; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; SURVIVAL ANALYSIS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 0033626036     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880215     Document Type: Article

References (31)

1. Cancer statistics, 1998
2. Mammalian G1 cyclins
3. 1 phase in rodent fibroblasts
4. 1/S phase transition by expression of cyclins D1 and E with an inducible system
5. A novel cyclin encoded by a bcl1-linked candidate oncogene
6. Cyclins and cancer II: Cyclin D1 and CDK inhibitors come of age
7. Altered expression of the cyclin D1 and retinoblastoma genes in human esophageal cancer
8. Cyclin D1 amplification in human laryngeal squamous cell carcinomas: Prognostic significance and clinical implications
9. Frequent amplification of the bcl-1 locus in head and neck squamous cell carcinomas
10. Amplification and overexpression of cyclin D1 in human hepatocellular carcinoma
11. Amplification and overexpression of the cyclin D1 gene in aggressive human hepatocellular carcinoma
12. Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis
13. Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions
14. Redundant cyclin overexpression and gene amplification in breast cancer cells
15. Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer
16. The prognostic value of NCAM, p53 and cyclin D1 in resected non-small cell lung cancer
17. A clinicopathological study on overexpression of cyclin D1 and of p53 in a series of 248 patients with operable breast cancer
18. Different expression patterns of cyclins A, D1 and E in human colorectal cancer
19. Cyclin E, a potential prognostic marker for breast cancer
20. A common path to tumor growth: Deregulation of Rb-dependent restriction point control
21. Cyclin D1 expression is regulated by the retinoblastoma protein
22. Regulation of cyclin E transcription by E2Fs and retinoblastoma protein
23. Cyclin D1 is a nuclear protein required for cell cycle progression in G1
24. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
25. Loss of Rb and Myc activation co-operate to suppress cyclin D1 and contribute to transformation
26. Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumor cell lines
27. Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity
28. Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts
29. Cyclin D1 as a cellular proto-oncogene
30. 1 cyclins
31. Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle