Biophysical characteristics of anti-Galα1-3Gal IgM binding to cell surfaces: Implications for xenotransplantation

Transplantation

Volumn 71, Issue 3, 2001, Pages 440-446

  Parker, William ^a   Stitzenberg, Karyn B ^a   Yu, Paul B ^a   Pratt, Valerie S W ^a   Nakamura, Yuko C ^a   Farel, Lily S ^a   Ward, Catherine M ^a   Lin, Shu S ^a   Everett, Mary Lou ^a   Platt, Jeffrey L ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; EPITOPE; IMMUNOGLOBULIN M ANTIBODY;

ANIMAL CELL; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; BLOOD GROUP ABO INCOMPATIBILITY; CELL SURFACE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DENATURATION; DISSOCIATION; DISULFIDE BOND; ENDOTHELIUM CELL; GRAFT REJECTION; HOST RESISTANCE; NONHUMAN; PRIORITY JOURNAL; SWINE; TEMPERATURE; VISCOSITY; XENOTRANSPLANTATION;

EID: 0035865120     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200102150-00018     Document Type: Article

References (33)

1. Origin of anti-human blood group B agglutinins in white leghorn chicks
2. Natural antibodies and the immune response
3. Blood-group substances
4. Isohemagglutinins and xenoreactive antibodies are members of a distinct family of natural antibodies
5. Specificity and function of "natural" antibodies in immunodeficient subjects: Clues to B-cell lineage and development
6. Xenoreactive natural antibodies: Isolation and initial characterization
7. The functional activities of IgG and IgM anti-A and anti-B
8. Fate of antigen in xenotransplantation: Implications for acute vascular rejection and accommodation
9. 4, isolated from Bandeiraea simplicifolia
10. An α-D-galactosyl-binding lectin from Bandeiraea simplicifolia seeds
11. An ELISA assay for xenoreactive natural antibodies
12. Specificity of xenoreactive anti-galα1-3 gal IgM for α-galactosyl ligands
13. Characterization of porcine endothelial cell determinants recognized by human natural antibodies
14. Ultrastructural demonstration of endothelial glycocalyx disruption in the reperfused rat heart: Involvement of oxygen free radicals
15. The structure and properties of the cell surface coat
16. Release of heparan sulfate from endothelial cells: Implications for the pathogenesis of hyperacute rejection
17. Shedding of heparan sulfate proteoglycan by stimulated endothelial cells: Evidence for proteolysis of cell surface molecules
18. Differential recognition by proteins of α-galactosyl residues on endothelial cell surfaces
19. The fate of antibodies bound to the surface of tumor cells in vitro
20. Re-evaluation of the concept of functional affinity as applied to bivalent antibody binding to cell surface antigens
21. Why is it so hard to dissociate multivalent antigens from cell-surface antibodies?
22. Extracorporeal (ex vivo) connection of pig kidneys to humans. II. The anti-pig antibody response
23. The humoral immune response in humans following cross-perfusion of porcine organs
24. Immunochemical properties of anti-Galα1-3Gal after sensitization with xenogeneic tissues
25. Limited specificity of xenoantibodies in diabetic patients transplanted with fetal porcine islet cell clusters: Main antibody reactivity against α-linked galactose-containing epitopes
26. Identification of porcine endothelial cell membrane antigens recognized by human xenoreactive antibodies
27. Focal adhesion proteins associated with apical stress fibers of human fibroblasts
28. Quantitative evaluation of porcine endothelial cell antigens recognized by human natural antibodies: An analysis by Western blotting
29. The human natural anti-Gal IgG. III. The subtlety of immune tolerance in man as demonstrated by crossreactivity between natural anti-Gal and anti-B antibodies
30. Specificities of human IgM and IgG anticarbohydrate xenoantibodies found in the sera of diabetic patients grafted with fetal pig islets
31. High-affinity anti-Gal immunoglobulin G in chronic rejection of xenografts
32. Mechanisms of injury in porcine livers perfused with blood of humans with fulminant hepatic failure
33. The role of antibodies in acute vascular rejection of pig-to-baboon cardiac transplants