Chapter 14 Determination of Zinc Using Carbonic Anhydrase-Based Fluorescence Biosensors

Methods in Enzymology

Volumn 450, Issue , 2008, Pages 287-309

  Bozym, Rebecca ^a,b   Hurst, Tamiika K ^c   Westerberg, Nissa ^a,d   Stoddard, Andrea ^c   Fierke, Carol A ^c   Frederickson, Christopher J ^e   Thompson, Richard B ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Cellumen Inc   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d United States Patent and Trademark Office   (United States)

^e NeuroBioTex Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE; ZINC;

BIOSENSOR; ENZYME ASSAY; ENZYME ISOLATION; FLUORESCENCE ANALYSIS; KINETICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; ARTICLE; CHEMISTRY; GENETIC PROCEDURES; METHODOLOGY; SPECTROFLUOROMETRY;

BIOSENSING TECHNIQUES; CARBONIC ANHYDRASES; SPECTROMETRY, FLUORESCENCE; ZINC;

EID: 58249091560     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(08)03414-9     Document Type: Review

References (55)

1. Aslamkhan A.G., Aslamkhan A., and Ahearn G.A. Preparation of metal ion buffers for biological experimentation: A methods approach with emphasis on iron and zinc. J. Exp. Zool. 292 (2002) 507-522
2. Axelrod D. Fluorescence polarization microscopy. In: Taylor D.L., and Wang Y.-L. (Eds). Methods in Cell Biology: Fluorescence Microscopy of Living Cells in Culture. Part B. Quantitative Fluorescence Microscopy-Imaging and Spectroscopy Vol. 30 (1989), Academic Press, New York 333-352
3. Baker J.O. Metal-buffered systems. Methods Enzymol. 158 (1988) 33-55
4. Berkow R. Merck Manual of Diagnosis and Therapy (1992), Merck Research Laboratories, Rahway, NJ 2844
5. Bozym R.A., Thompson R.B., Stoddard A.K., and Fierke C.A. Measuring picomolar intracellular exchangeable zinc in PC-12 cells using a ratiometric fluorescence biosensor. ACS Chem. Biol. 1 (2006) 103-111
6. Chen R.F., and Kernohan J. Combination of bovine carbonic anhydrase with a fluorescent sulfonamide. J. Biol. Chem. 242 (1967) 5813-5823
7. Christianson D.W., and Fierke C.A. Carbonic anhydrase-Evolution of the zinc binding site by nature and by design. Acc. Chem. Res. 29 (1996) 331-339
8. Cotton F.A., and Wilkinson G. Advanced Inorganic Chemistry (1988), Wiley-Interscience, New York
9. DiTusa C.A., McCall K.A., Christensen T., Mahapatro M., Fierke C.A., and Toone E.J. Thermodynamics of metal ion binding. II. Metal ion binding by carbonic anhydrase variants. Biochemistry 40 (2001) 5345-5351
10. Dix J.A., and Verkman A.S. Mapping of fluorescence anisotropy in living cells by ratio imaging: Application to cytoplasmic viscosity. Biophys. J. 57 (1990) 231-240
11. Eftink M.R. Fluorescence methods for studying equilibrium macromolecule-Ligand interactions. In: Brand L., and Johnson M.L. (Eds). Fluorescence Spectroscopy Vol. 278 (1997), Academic Press, New York 221-257
12. Elbaum D., Nair S.K., Patchan M.W., Thompson R.B., and Christianson D.W. Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J. Am. Chem. Soc. 118 (1996) 8381-8387
13. Eriksson A.E., and Jones T.A. Refined structure of human carbonic anhydrase II at 2.0A resolution. Proteins 4 (1988) 274-282
14. Fierke C.A., and Thompson R.B. Fluorescence-based biosensing of zinc using carbonic anhydrase. BioMetals 14 (2001) 205-222
15. Forster T. Intermolecular energy migration and fluorescence (Ger.). Ann. Phys. 2 (1948) 55-75
16. Frederickson C.J., Giblin L.J., Krezel A., McAdoo D.J., Muelle R.N., Zeng Y., Balaji R.V., Masalha R., Thompson R.B., Fierke C.A., Sarvey J.M., Valdenebro M.d., Prough D.S., and Zornow M.H. Concentrations of extracellular free zinc (pZn)e in the central nervous system during simple anesthetization, ischemia, and reperfusion. Exp. Neurol. 198 (2006) 285-293
17. Huang C.-c., Lesburg C.A., Kiefer L.L., Fierke C.A., and Christianson D.W. Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry 35 (1996) 3439-3446
18. Hunt J.B., Rhee M.J., and Storm C.B. A rapid and convenient preparation of apocarbonic anhydrase. Anal. Biochem. 79 (1977) 614-617
19. Hunt J.A., Ahmed M., and Fierke C.A. Metal binding specificity in carbonic anhydrase is influenced by conserved hydrophobic amino acids. Biochemistry 38 (1999) 9054-9060
20. Ippolito J.A., Baird T.T., McGee S.A., Christianson D.W., and Fierke C.A. Structure-assisted redesign of a protein-zinc binding site with femtomolar affinity. Proc. Natl Acad. Sci. USA 92 (1995) 5017-5021
21. Kiefer L.L., and Fierke C.A. Functional characterization of human carbonic anhydrase II variants with altered zinc binding sites. Biochemistry 33 (1994) 15233-15240
22. Kiefer L.L., Paterno S.A., and Fierke C.A. Hydrogen bond network in the metal binding site of carbonic anhydrase enhances zinc affinity and catalytic efficiency. J. Am. Chem. Soc. 117 (1995) 6831-6837
23. Lesburg C.A., Huang C.-c., Christianson D.W., and Fierke C.A. Histidine to carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry 36 (1997) 15780-15791
24. Lindskog S., Henderson L.E., Kannan K.K., Liljas A., Nyman P.O., and Strandberg B. Carbonic anhydrase. In: Boyer P.D. (Ed). The Enzymes Vol. 5 (1971), Academic Press, New York 587-665
25. Maren T.H. Use of inhibitors in physiological studies of carbonic anhydrase. Am. J. Physiol. 232 (1977) F291-F297
26. McCall K.A. Department of Biochemistry (2000), Duke University, Durham, NC 190
27. McCall K.A., and Fierke C.A. Probing determinants of the metal ion selectivity in carbonic anhydrase using mutagenesis. Biochemistry 43 (2004) 3979-3986
28. Moffett J.W., Brand L.E., Croot P.L., and Barbeau K.A. Cu speciation and cyanobacterial distribution in harbors subject to anthropogenic Cu inputs. Limnol. Oceanogr. 42 (1997) 789-799
29. Nolan E.M., Jaworski J., Okamoto K.-I., Hayashi Y., Sheng M., and Lippard S.J. Qz1 and Qz2: Rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). J. Am. Chem. Soc. 127 (2005) 16812-16823
30. Nuccitelli R. A practical guide to the study of calcium in living cells. In: Wilson L., and Matsudaira P. (Eds). Methods in Cell Biology Vol. 40 (1994), Academic Press, New York 364
31. Price P.J., and Brewer G.J. Serum-free media for neural cell cultures. In: Federoff S., and Richardson A. (Eds). Protocols for Neural Cell Culture (2001), Humana Press, Totowa, NJ 255-264
32. Rizzuto R., Nakase H., Darras B., Francke U., Fabrizi G.M., Mengel T., Walsh F., Kadenbach B., DiMauro S., and Schon E.A. A gene specifying subunit VIII of human cytochrome c oxidase is localized to chromosome 11 and is expressed in both muscle and non-muscle tissues. J. Biol. Chem. 264 (1989) 10595-10600
33. Rizzuto R., Brini M., Pizzo P., Murgia M., and Pozzan T. Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells. Curr. Biol. 5 (1995) 635-642
34. Schwarze S.R., Ho A., Vocero-Akbani A., and Dowdy S.F. In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 285 (1999) 1569-1572
35. Stumm W., and Morgan J.J. Aquatic Chemistry: Chemical Equilibria and Rates in Natural Waters (1996), Wiley-Interscience, New York
36. Supuran C.T., and Scozzafava A. Carbonic anhydrase inhibitors and their therapeutic potential. Exp. Opin. Ther. Patents 10 (2000) 575-600
37. Szmacinski H., and Lakowicz J.R. Optical measurements of pH using fluorescence lifetimes and phase-modulation fluorometry. Anal. Chem. 65 (1993) 1668-1674
38. Szmacinski H., and Lakowicz J.R. Lifetime-based sensing. In: Lakowicz J.R. (Ed). Topics in Fluorescence Spectroscopy, Vol. 4: Probe Design and Chemical Sensing (1994), Plenum, New York 295-334
39. Thompson R.B., and Jones E.R. Enzyme-based fiber optic zinc biosensor. Anal. Chem. 65 (1993) 730-734
40. Thompson R.B., and Patchan M.W. Fluorescence lifetime-based biosensing of zinc: Origin of the broad dynamic range. J. Fluorescence 5 (1995) 123-130
41. Thompson R.B., and Patchan M.W. Lifetime-based fluorescence energy transfer biosensing of zinc. Anal. Biochem. 227 (1995) 123-128
42. Thompson R.B., Maliwal B.P., Feliccia V.L., Fierke C.A., and McCall K. Determination of picomolar concentrations of metal ions using fluorescence anisotropy: Biosensing with a "reagentless" enzyme transducer. Anal. Chem. 70 (1998) 4717-4723
43. Thompson R.B., Maliwal B.P., and Fierke C.A. Expanded dynamic range of free zinc ion determination by fluorescence anisotropy. Anal. Chem. 70 (1998) 1749-1754
44. Thompson R.B., Maliwal B.P., and Fierke C.A. Fluorescence-based sensing of transition metal ions by a carbonic anhydrase transducer with a tethered fluorophore. In: Lakowicz J.R., Soper S.A., and Thompson R.B. (Eds). SPIE Conference on Advances in Fluorescence Sensing Technology IV Vol. 3602 (1999), SPIE, Bellingham, WA 85-92
45. Thompson R.B., Whetsell Jr. W.O., Maliwal B.P., Fierke C.A., and Frederickson C.J. Fluorescence microscopy of stimulated Zn(II) release from organotypic cultures of mammalian hippocampus using a carbonic anhydrase-based biosensor system. J. Neurosci. Methods 96 (2000) 35-45
46. Thompson R.B., Maliwal B.P., and Zeng H.H. Zinc biosensing with multiphoton excitation using carbonic anhydrase and improved fluorophores. J. Biomed. Opt. 5 (2000) 17-22
47. Thompson R.B., Cramer M.L., Bozym R., and Fierke C.A. Excitation ratiometric fluorescent biosensor for zinc ion at picomolar levels. J. Biomed. Opt. 7 (2002) 555-560
48. Thompson R.B., Peterson D., Mahoney W., Cramer M., Maliwal B.P., Suh S.W., and Frederickson C.J. Fluorescent zinc indicators for neurobiology. J. Neurosci. Methods 118 (2002) 63-75
49. Thompson R.B., Frederickson C.J., Fierke C.A., Westerberg N.M., Bozym R.A., Cramer M.L., and Hershfinkel M. Practical aspects of fluorescence analysis of free zinc ion in biological systems: pZn for the biologist. In: Thompson R.B. (Ed). Fluorescence Sensors and Biosensors (2006), CRC Press, Boca Raton, FL 351-376
50. van den Berg C. Determining the copper complexing capacity and conditional stability constants of complexes of copper (II) with natural organic ligands in seawater by cathodic stripping voltammetry of copper-catechol complex ions. Mar. Chem. 15 (1984) 1-18
51. Weber G. Photoelectric method for the measurement of the polarization of the fluorescence of solutions. J. Opt. Soc. Am. 46 (1956) 962-970
52. Weber G. Protein Interactions (1992), Chapman & Hall, New York
53. Zeng H.H., Thompson R.B., Maliwal B.P., Fones G.R., Moffett J.W., and Fierke C.A. Real-time determination of picomolar free Cu(II) in seawater using a fluorescence-based fiber optic biosensor. Anal. Chem. 75 (2003) 6807-6812
54. Zeng H.-H., Bozym R.A., Rosenthal R.E., Fiskum G., Cotto-Cumba C., Westerberg N., Fierke C.A., Stoddard A., Cramer M.L., Frederickson C.J., and Thompson R.B. In situ measurement of free zinc in an ischemia model and cell culture using a ratiometric fluorescence-based biosensor. In: Vo-Dinh T., Grundfest W.S., Benaron D.A., and Cohn G.E. (Eds). SPIE Conference on Advanced Biomedical and Clinical Diagnostic Systems III Vol. 5692 (2005), SPIE, San Jose, CA 51-59
55. Zirino A., and Yamamoto S. A pH-dependent model for the chemical speciation of copper, zinc, cadmium, and lead in seawater. Limnol. Oceanogr. 17 (1972) 661-671