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Volumn 50, Issue 9, 2009, Pages 1020-1022

Cross-metathesis of α-methylene-β-lactams: the first tetrasubstituted alkenes by CM

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE DERIVATIVE; ALKYL GROUP; BETA LACTAM DERIVATIVE; CARBENE;

EID: 58149520216     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.12.060     Document Type: Article
Times cited : (37)

References (30)
  • 2
    • 3042617004 scopus 로고    scopus 로고
    • and references therein
    • Buynak J.D. Curr. Med. Chem. 11 (2004) 1951 and references therein
    • (2004) Curr. Med. Chem. , vol.11 , pp. 1951
    • Buynak, J.D.1
  • 12
    • 0038215596 scopus 로고    scopus 로고
    • For recent reviews on cross metathesis, see:
    • For recent reviews on cross metathesis, see:. Connor S.J., and Blechert S. Angew. Chem., Int. Ed. 42 (2003) 1900
    • (2003) Angew. Chem., Int. Ed. , vol.42 , pp. 1900
    • Connor, S.J.1    Blechert, S.2
  • 20
    • 58149482272 scopus 로고    scopus 로고
    • note
    • 1H NMR. Resonances for the exocyclic alkene proton, for all β-lactam cross products, were consistent with our NOE based E/Z assignments of α-alkylidene-β-lactones.
  • 27
    • 58149494863 scopus 로고    scopus 로고
    • note
    • Interestingly, during the silica gel chromatographic purification of entry 4 (Table 2), there was significant isomerization of the exocyclic alkenes to the corresponding α,β-unsaturated esters (see Supplementary data).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.