Mechanism of NS2B-mediated activation of NS3pro in dengue virus: Molecular dynamics simulations and bioassays

Journal of Virology

Volumn 83, Issue 2, 2009, Pages 1060-1070

  Zuo, Zhili ^a   Oi, Wah Liew ^a   Chen, Gang ^a   Chong, Pek Ching Jenny ^a   Siew, Hui Lee ^a   Chen, Kaixian ^b   Jiang, Hualiang ^b   Chum, Mok Puah ^a   Zhu, Weiliang ^b  

^a SINGAPORE POLYTECHNIC   (Singapore)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; GLUTAMIC ACID; HYDROGEN; NS2B COFACTOR; NS3 PROTEASE; PROTEINASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BIOASSAY; DENGUE VIRUS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; HYDROGEN BOND; HYDROPHOBICITY; KINETICS; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MUTAGENESIS; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN VARIANT; SIMULATION; WILD TYPE;

AMINO ACID SEQUENCE; DENGUE VIRUS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SERINE ENDOPEPTIDASES; VIRAL NONSTRUCTURAL PROTEINS;

DENGUE VIRUS; FLAVIVIRUS;

EID: 58149487623     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01325-08     Document Type: Article

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