Alcohol feeding blocks methacholine-induced airway responsiveness in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 296, Issue 1, 2009, Pages

  Oldenburg, P J ^a   Wyatt, T A ^a,b   Factor, P H ^c   Sisson, J H ^a,d  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

^c Columbia University ^*

^d UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

Author keywords

Bronchodilator effect; Enhanced pause; Penh

Indexed keywords

ALCOHOL; METHACHOLINE; SODIUM CHLORIDE;

AIR CONDITIONING; ALCOHOL BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ARTIFICIAL VENTILATION; BREATHING; BRONCHODILATATION; CONTROLLED STUDY; LUNG FUNCTION; LUNG RESISTANCE; MALE; MOUSE; NONHUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; AIRWAY RESISTANCE; ANIMALS; BRONCHOCONSTRICTOR AGENTS; BRONCHODILATOR AGENTS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DRINKING; DRUG INTERACTIONS; ETHANOL; INJECTIONS, INTRAVENOUS; LUNG; MALE; METHACHOLINE CHLORIDE; MICE; MICE, INBRED C57BL; PLETHYSMOGRAPHY, WHOLE BODY;

EID: 58149484170     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00487.2007     Document Type: Article

References (42)

1. Agrawa] DK, Hopfenspirger MT, Chavez J, Talmadge JE. Flt3 ligand: a novel cytokine prevents allergic asthma in a mouse model. Int Immunopharmacol 1: 2081-2089, 2001.
2. Ayres J, Ancic P, Clark TJ. Airways responses to oral ethanol in normal subjects and in patients with asthma. J R Soc Med 75: 699-704, 1982.
3. Ayres JG, Clark TJ. Intravenous ethanol can provide bronchodilatation in asthma. Clin Sci (Lond) 64: 555-557, 1983.
4. Ballenger JJ. Experimental effect of cigarette smoke on human respiratory cilia. N Engl J Med 263: 832-835, 1960.
5. Boe DM, Nelson S, Zhang P, Bagby GJ. Acute ethanol intoxication suppresses lung chemokine production following infection with Streptococcus pneumoniae. J Infect Dis 184: 1134 -1142, 2001.
6. Brown EA. The use of intravenous ethyl alcohol in the treatment of status asthmaticus. Ann Allergy 5: 193-195, 1947.
7. Carvalho EM, Brito GA, Pessoa BB, Ribeiro RA, Capaz FR. Long-term ethanol intoxication reduces inflammatory responses in rats. Braz J Med Biol Res 38: 81-89, 2005.
8. Chong BT, Agrawal DK, Romero FA, Townley RG. Measurement of bronchoconstriction using whole-body plethysmograph: comparison of freely moving versus restrained guinea pigs. J Pharmacol Toxicol Methods 39: 163-168, 1998.
9. Cuddy R, Li G. The role of alcohol in asthma: a review of clinical and experimental studies. Am J Emerg Med 19: 501-503, 2001.
10. Elliott MK, Sisson JH, West WW, Wyatt TA. Differential in vivo effects of whole cigarette smoke exposure versus cigarette smoke extract on mouse ciliated tracheal epithelium. Exp Lung Res 32: 99 -118, 2006.
11. Elliott MK, Sisson JH, Wyatt TA. Effects of cigarette smoke and alcohol on ciliated tracheal epithelium and inflammatory cell recruitment. Am J Respir Cell Mol Biol 36: 452-459, 2007.
12. Fredberg JJ. Bronchospasm and its biophysical basis in airway smooth muscle. Respir Res 5: 2, 2004.
13. Grant BF. Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States: results of the National Longitudinal Alcohol Epidemiologic Survey. J Stud Alcohol 58: 464-473, 1997.
14. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 156: 766-775, 1997.
15. 2+ sensitivity in airway smooth muscle. Anesth Analg 92: 767-774, 2001.
16. Happel KI, Odden AR, Zhang P, Shellito JE, Bagby GJ, Nelson S. Acute alcohol intoxication suppresses the interleukin 23 response to Klebsiella pneumoniae infection. Alcohol Clin Exp Res 30: 1200-1207, 2006.
17. Herxheimer H, Stresemann E. Ethanol and lung function in bronchial asthma. Arch Int Pharmacodyn Ther 144: 310-314, 1963.
18. Hogman M, Frostell C, Arnberg H, Hedenstierna G. Inhalation of nitric oxide modulates methacholine-induced bronchoconstriction in the rabbit. Eur Respir J 6: 177-180, 1993.
19. Humbles AA, Lloyd CM, McMillan SJ, Friend DS, Xanthou G, McKenna EE, Ghiran S, Gerard NP, Yu C, Orkin SH, Gerard C. A critical role for eosinophils in allergic airways remodeling. Science 305: 1776 -1779, 2004.
20. Joshi PC, Guidot DM. The alcoholic lung: epidemiology, pathophysiology, and potential therapies. Am J Physiol Lung Cell Mol Physiol 292: L813-L823, 2007.
21. Justice JP, Shibata Y, Sur S, Mustafa J, Fan M, Van Scott MR. IL-10 gene knockout attenuates allergen-induced airway hyperresponsiveness in C57BL/6 mice. Am J Physiol Lung Cell Mol Physiol 280: L363-L368, 2001.
22. King GG, Pare PD, Seow CY. The mechanics of exaggerated airway narrowing in asthma: the role of smooth muscle. Respir Physiol 118: 1-13, 1999.
23. Leake C. The Old Egyptian Medical Papyri. Lawrence, KS: University of Kansas Press, 1952.
24. Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA. Increased pulmonary responses to acute ozone exposure in obese db/db mice. Am J Physiol Lung Cell Mol Physiol 290: L856-L865, 2006.
25. Ma X, Cheng Z, Kong H, Wang Y, Unruh H, Stephens NL, Laviolette M. Changes in biophysical and biochemical properties of single bronchial smooth muscle cells from asthmatic subjects. Am J Physiol Lung Cell Mol Physiol 283: L1181-L1189, 2002.
26. Oldenburg PJ, Mustafa SJ. Involvement of mast cells in adenosine- mediated bronchoconstriction and inflammation in an allergic mouse model. J Pharmacol Exp Ther 313: 319-324, 2005.
27. Richards IS, Kulkarni AP, Brooks SM. Ethanol-induced bronchodila-tation in TEA-treated canine tracheal smooth muscle is mediated by a beta-adrenoceptor-dependent mechanism. Eur J Pharmacol 167: 155-160, 1989.
28. Rivera-Sanchez YM, Johnston RA, Schwartzman IN, Valone J, Sil-verman ES, Fredberg JJ, Shore SA. Differential effects of ozone on airway and tissue mechanics in obese mice. J Appl Physiol 96: 2200- 2206, 2004.
29. Salter H. On the treatment of asthmatic paroxysm by fulkl doses of alcohol. Lancet ii: 558 -559, 1863.
30. Shore SA, Rivera-Sanchez YM, Schwartzman IN, Johnston RA. Responses to ozone are increased in obese mice. J Appl Physiol 95: 938 -945, 2003.
31. Sisson JH. Alcohol and airways function in health and disease. Alcohol 41: 293-307, 2007.
32. Solway J, Fredberg JJ. Perhaps airway smooth muscle dysfunction contributes to asthmatic bronchial hyperresponsiveness after all. Am J Respir Cell Mol Biol 17: 144-146, 1997.
33. Song K, Coleman RA, Zhu X, Alber C, Ballas ZK, Waldschmidt TJ, Cook RT. Chronic ethanol consumption by mice results in activated splenic T cells. J Leukoc Biol 72: 1109-1116, 2002.
34. Sterk PJ, Bel EH. Bronchial hyperresponsiveness: the need for a distinction between hypersensitivity and excessive airway narrowing. Eur Respir J 2: 267-274, 1989.
35. Swartz MH, Repke DI, Katz AM, Rubin E. Effects of ethanol on calcium binding and calcium uptake by cardiac microsomes. Biochem Pharmacol 23: 2369-2376, 1974.
36. Tabakoff B, Nelson E, Yoshimura M, Hellevuo K, Hoffman PL. Phosphorylation cascades control the actions of ethanol on cell cAMP signalling. J Biomed Sci 8: 44-51, 2001.
37. Trevisani M, Gazzieri D, Benvenuti F, Campi B, Dinh QT, Groneberg DA, Rigoni M, Emonds-Alt X, Creminon C, Fischer A, Geppetti P, Harrison S. Ethanol causes inflammation in the airways by a neurogenic and TRPV1-dependent mechanism. J Pharmacol Exp Ther 309: 1167-1173, 2004.
38. Woolcock AJ, Peat JK. Epidemiology of bronchial hyperresponsiveness. Clin Rev Allergy 7: 245-256, 1989.
39. Wyatt TA, Forget MA, Sisson JH. Ethanol stimulates ciliary beating by dual cyclic nucleotide kinase activation in bovine bronchial epithelial cells. Am J Pathol 163: 1157-1166, 2003.
40. Wyatt TA, Gentry-Nielsen MJ, Pavlik JA, Sisson JH. Desensitization of PKA-stimulated ciliary beat frequency in an ethanol-fed rat model of cigarette smoke exposure. Alcohol Clin Exp Res 28: 998 -1004, 2004.
41. Wyatt TA, Sisson JH. Chronic ethanol downregulates PKA activation and ciliary beating in bovine bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 281: L575-L581, 2001.
42. Yao L, Asai K, Jiang Z, Ishii A, Fan P, Gordon AS, Diamond I. Dopamine D2 receptor inhibition of adenylyl cyclase is abolished by acute ethanol but restored after chronic ethanol exposure (tolerance). J Pharmacol Exp Ther 298: 833-839, 2001.