An expeditious synthesis for γ-carboline analogue 4-aryl-1,3-thiazino[6,5-b]indole derivatives via the trifluoromethanesulfonic acid-promoted isomerization of 3-amidomethylthioindole intermediates to 2-indolyl sulfides

Tetrahedron

Volumn 65, Issue 7, 2009, Pages 1475-1480

  Csomós, Péter ^a,b,c   Fodor, Lajos ^a,b,c   Bernáth, Gábor ^b,c   Csámpai, Antal ^d   Sohár, Pál ^d  

^a Department of Pediatrics   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

1H and 13C NMR; Bischler Napieralski reaction; IR; Isomerization; Thiazino 6,5 b indole; Trifluoromethanesulfonic acid

Indexed keywords

2 INDOLYL SULFIDE; 3 AMIDOMETHYLTHIOINDOLE; 4 ARYL 1,3 THIAZINO[6,5 B] INDOLE DERIVATIVE; GAMMA CARBOLINE DERIVATIVE; INDOLE DERIVATIVE; INDOLIZINE DERIVATIVE; ISOMERASE; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BISCHLER NAPIERALSKI REACTION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL BOND; CHEMICAL REACTION; CHEMICAL STRUCTURE; CROSS COUPLING REACTION; INFRARED SPECTROMETRY; ISOMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 58149483480     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.11.099     Document Type: Article

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